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NLVSGFRSFGWPSRMLMINQFGINLGFYMLMPYLAGYLAGPLGLAAWAIGLVLGVRNFSQQGMFIIGGTL ADRLGYKPLIVAGCVLRTVGFGLLVLADSLPAVLIASAATGFAGALFNPAVRAYLAVDAGPRRLEAFALF NVFYQGGILAGPLVGLALMFVDFRATAAAAAMVFAVLTVAQLFALPQRTAAPAEAKTSVLDDWRVVAANR SFLLFAAAMIGSYVLSFQVYLALPLQARDLFPGSDSVVTAMIFVVSGLVAVMGQMRITRWFAKRWGAGRS LMIGMLILAVSFVPLMALPDDTRAGRVAAATALLGATAVLAVGSAAVFPFEMDTVVSLAGNRLVGTHYGF YNTIVGVGILVGNLATGYLMQAAKRVGAPELLWVLLCAIGAVSALALYRLDRRGLLQPAKSTPDRAVAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5855 | - | - | 100% (420) | major facilitator superfamily transporter |
| M. vanbaalenii PYR-1 | Mvan_2778 | - | 9e-10 | 25.57% (348) | major facilitator superfamily transporter |
| M. vanbaalenii PYR-1 | Mvan_1951 | - | 3e-09 | 28.57% (196) | major facilitator superfamily transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0872 | - | 1e-149 | 66.67% (396) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0900 | - | 0.0 | 85.71% (420) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0849 | - | 1e-149 | 66.67% (396) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1274 | - | 1e-145 | 63.79% (417) | ABC transporter permease |
| M. marinum M | MMAR_4767 | - | 1e-152 | 66.83% (404) | integral membrane transport protein |
| M. avium 104 | MAV_0138 | - | 4e-08 | 22.22% (324) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_5167 | - | 4e-13 | 26.60% (282) | major facilitator superfamily protein MFS_1 |
| M. thermoresistible (build 8) | TH_3412 | - | 1e-11 | 26.68% (401) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0338 | - | 1e-150 | 66.34% (404) | integral membrane transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5855|M.vanbaalenii_PYR-1 ----------------MNLVSGFRSFGWPSRMLMINQFGINLGFYMLMPY
Mflv_0900|M.gilvum_PYR-GCK ----------------MTLLSGFGSFGWPSRMLMINQFGINLGFYMLMPY
Mb0872|M.bovis_AF2122/97 ----------------MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPY
Rv0849|M.tuberculosis_H37Rv ----------------MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPY
MMAR_4767|M.marinum_M ----------------MGFLAQFRSFNRPSRVLMINQFGINVGFYMLMPY
MUL_0338|M.ulcerans_Agy99 ----------------MGFLAQFRSFNRPSRVLMINQFGINVGFYMLMPY
MAB_1274|M.abscessus_ATCC_1997 MDQAHPRDRPDREEGVIQTLRQFRSFDRPSQILMVNQFAINVGFYMLMPY
TH_3412|M.thermoresistible__bu ----------------MTQCAVRAGAREWAGLGVLAVPTVLLGLDVTVLY
MSMEG_5167|M.smegmatis_MC2_155 ----------------MPHTRRFS-----FALLAYAFAAIMVGTTLPTPM
MAV_0138|M.avium_104 ----------------MMSSNVRAARNRPGRTDPQPPTGAPLFVGVLGLL
: : :
Mvan_5855|M.vanbaalenii_PYR-1 LAG-YLAGPLG-----------LAAWAIGLVLGVRNFSQQGMFIIGGTLA
Mflv_0900|M.gilvum_PYR-GCK LAG-YLAGPLG-----------LAAWAIGLVLGVRNFSQQGMFIIGGTLA
Mb0872|M.bovis_AF2122/97 LAD-YLAGPLG-----------LAAWAVGLVMGVRNFSQQGMFFVGGTLA
Rv0849|M.tuberculosis_H37Rv LAD-YLAGPLG-----------LAAWAVGLVMGVRNFSQQGMFFVGGTLA
MMAR_4767|M.marinum_M LAD-YLAGPLG-----------LAAWAVGLVMGVRNFSQQGMFFVGGTLA
MUL_0338|M.ulcerans_Agy99 LAD-YLAGPLG-----------LAAWAVGLVMGVRNFSQQGMFFVGGTLA
MAB_1274|M.abscessus_ATCC_1997 LAG-YLAGPLG-----------LAAWMVGLVLGVRNFSQQGMFLVGGTLA
TH_3412|M.thermoresistible__bu LVLPAVAADLA-----------PSPVQTLWIMDAYGFFIAGFLITMGTLG
MSMEG_5167|M.smegmatis_MC2_155 YAL--YAEHMN-----------FAVLTTTVIYATYAGGVLFALLLFGRWS
MAV_0138|M.avium_104 LATGWVANHFVGLMPAISDRDHLATTTLDGIFGIYALGLLPGLLVGGRTS
. * : : : :: * .
Mvan_5855|M.vanbaalenii_PYR-1 DRLGYKPLIVAGCVLRTVGFGLLVLADSLPAVLIASAATGFAGALFNPAV
Mflv_0900|M.gilvum_PYR-GCK DRLGFKPLIVSGCVLRTAGFGLLVFADSLPAVLVASAATGFAGALFNPAV
Mb0872|M.bovis_AF2122/97 DRFGYKPLIIAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNPAV
Rv0849|M.tuberculosis_H37Rv DRFGYKPLIIAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNPAV
MMAR_4767|M.marinum_M DRFGYKPLIVAGCLIRTGGFALLVVAQSLPSVLIASAATGFAGALFNPAV
MUL_0338|M.ulcerans_Agy99 DRFGYKPLIVAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNPAV
MAB_1274|M.abscessus_ATCC_1997 DRFGYKPLIVAGCFLRTAGFAMLAFVGTLPAILIASAATGFAGALFNPAV
TH_3412|M.thermoresistible__bu DRIGRRRLLTIGVTAFAGASVLAALAPSAELLIVARALLGVAGATLMPST
MSMEG_5167|M.smegmatis_MC2_155 DAIGRRPMLLAGVAAALISAGVFLMADSVPVLLIGRIFSGLSAGIFTGTA
MAV_0138|M.avium_104 DALGRRPVALTGSAAALVGTVAMLLSQHSPALFAGRLIVGLGVGLAISAG
* :* : : * . . :: . *.. . :
Mvan_5855|M.vanbaalenii_PYR-1 RAYLA--VDAGPRRLEAFALFNVFYQGGILAGPLVG-----------LAL
Mflv_0900|M.gilvum_PYR-GCK RAYLA--ADAGPRRLEAFALFNVFYQAGILAGPLVG-----------LAL
Mb0872|M.bovis_AF2122/97 RGYLA--AEAGERKIEAFAMFNVFYQSGILLGPLVG-----------LVL
Rv0849|M.tuberculosis_H37Rv RGYLA--AEAGERKIEAFAMFNVFYQSGILLGPLVG-----------LVL
MMAR_4767|M.marinum_M RAYVA--ADSGDRKLEAFAMFNIFYQAGILLGPLVG-----------LAL
MUL_0338|M.ulcerans_Agy99 RAYVA--ADSGDRKLEAFATFNIFYQAGILLGPLVG-----------LAL
MAB_1274|M.abscessus_ATCC_1997 RAYLA--ADSGERRVEAFAVFNVFYQAGILFGPIVG-----------LAL
TH_3412|M.thermoresistible__bu LSLISNMFVDAAQRALAIGVWATMFAVGMAAGPVVGGALVDRFWWGAAFL
MSMEG_5167|M.smegmatis_MC2_155 TAAVIE-AAPPAWRTRAAAVATVANIGGLGTGPLLAG---------LLVE
MAV_0138|M.avium_104 TAWAS-----DLRGPAGAATAGAVLTAGFAVGPFAGG---------VLAW
. . . *: **. .
Mvan_5855|M.vanbaalenii_PYR-1 MFVDFRATAAAAAMVFAVLTVAQLFALPQRTAAPAE--AKTSVLDDWRVV
Mflv_0900|M.gilvum_PYR-GCK MFVDFKITAAAAALVFAVLTVAQLFALPQRAVAPTP--EKTSVLQDWRAV
Mb0872|M.bovis_AF2122/97 LALDFRITVLAAAGVFGLLTVAQLVALPQHRADSER--EKTSILQDWRVV
Rv0849|M.tuberculosis_H37Rv LALDFRITVLAAAGVFGLLTVAQLVALPQHRADSER--EKTSILQDWRVV
MMAR_4767|M.marinum_M LTLDFRMTVLGASAVFAVLTAAQLMALPQHLADPGT--KNESILQGWKAI
MUL_0338|M.ulcerans_Agy99 LTLDFRMTVLGASAVFAVLTAAQLMALPQHLADPDT--KNESILQGWKAI
MAB_1274|M.abscessus_ATCC_1997 TAWDFRITCAVAAAVFAFLTVIQLMALPPNRAESERNADRAPVLTSWRSV
TH_3412|M.thermoresistible__bu LAVPVAAAVLLGARLLPEYADPQAGRLDLRSVALSLLAILAAIYAVKHVA
MSMEG_5167|M.smegmatis_MC2_155 YAPRPLHLSFVVHIVMAVLAGAAVFAVPETSSRSGS-------IGLQRLS
MAV_0138|M.avium_104 AGPSGVRASFALAAAILALAAFAVVAAPQPSPVTAP-------ADPDGEE
: :
Mvan_5855|M.vanbaalenii_PYR-1 AANRSFLLFAAAMIGSYVLSFQVYLALPLQARDLFP---GSDSVVTAMIF
Mflv_0900|M.gilvum_PYR-GCK AANRSFLLFAAAMIGSYVLSFQVYLAMPLQARYLFP---QNDSVVTAMIF
Mb0872|M.bovis_AF2122/97 VRNRPFLTLAAAMTGCYALSFQIYLALPMQASILMP---RNQYLLIAAMF
Rv0849|M.tuberculosis_H37Rv VRNRPFLTLAAAMTGCYALSFQIYLALPMQASILMP---RNQYLLIAAMF
MMAR_4767|M.marinum_M VRNRSFLGFAAAMTGAYVLSFQVYLALPMQASLLAP---GHQSVLVAAMF
MUL_0338|M.ulcerans_Agy99 VCNRSFLGFAAAMTGAYVLSFQVYLALPIQASLLAP---GHQSVLLAAMF
MAB_1274|M.abscessus_ATCC_1997 VSNKAFLLFSGAMIGSYVLTFQVYLALPLQAALLTDDK-KSETALVTSIF
TH_3412|M.thermoresistible__bu VHGVDGVAVAACALAAAAATVFVHRQRRLDAPLLDVTLFADRAFTAALTV
MSMEG_5167|M.smegmatis_MC2_155 VPPEVRTVFVIAAIAAFAGFAVTGMYTAVAPSFLSN-------VIGVDNH
MAV_0138|M.avium_104 TADAAPQGISRALSWAMPLAPWVFASATLGFVTIPG---RLHTALAAPVA
. . . . : : .
Mvan_5855|M.vanbaalenii_PYR-1 VVSGLVAVMG----------------QMRITRWFAKRWGAGRSLMIGMLI
Mflv_0900|M.gilvum_PYR-GCK VVSGVVAVLG----------------QMRITRWFGRRWGSGRSLAIGMLI
Mb0872|M.bovis_AF2122/97 AVSGLVAVGG----------------QLRITRWFAVRWGAERSLVVGATI
Rv0849|M.tuberculosis_H37Rv AVSGLVAVGG----------------QLRITRWFAVRWGAERSLVVGATI
MMAR_4767|M.marinum_M AVSGLIAIAG----------------QLRITRWFAAHWRVSRSLVVGAAI
MUL_0338|M.ulcerans_Agy99 AVSGLIAIAG----------------QLRITRWVAAHWRVSRSLVVGAAI
MAB_1274|M.abscessus_ATCC_1997 VVSGLVAIAG----------------QVRLTGWLSARFGPSRSLVLGMLV
TH_3412|M.thermoresistible__bu LLIGLIGVGGTMYLVTQFLQLVEGLTPVRAGWWMGPPALAMFVAAIGAPL
MSMEG_5167|M.smegmatis_MC2_155 AVAGAVACSIFA--------------ASAVTQVLANRVQPGRAVAVGCAI
MAV_0138|M.avium_104 AGTATLIVNG----------------VSGAVQVLARALRWGPQAGTAGAV
. : .. . :
Mvan_5855|M.vanbaalenii_PYR-1 LAVSFVPLMALPDDT----------RAGRVAAATALLGATAVLAVGSAAV
Mflv_0900|M.gilvum_PYR-GCK LALSFLPLIALPDDE----------RAGRVAAATALLIATAVLAVGSAAV
Mb0872|M.bovis_AF2122/97 LAASFIPVAVIPNGQ----------RFGVAVAVMALVLSASLLAVASAAL
Rv0849|M.tuberculosis_H37Rv LAASFIPVAVIPNGQ----------RFGVAVAVMALVLSASLLAVASAAL
MMAR_4767|M.marinum_M LAIAFVPLAMVPNAQ----------RFGTGAAVAALLVSASLLAVASAAL
MUL_0338|M.ulcerans_Agy99 LAMAFVPLAMVPNAQ----------RFGTGAAVAALLVSASLLAVASAAL
MAB_1274|M.abscessus_ATCC_1997 IGTAFVPLVLLPTAA----------SAGQLAAIAALLFSAALLAVGTIAT
TH_3412|M.thermoresistible__bu IARRVRPGVVMAATLGVSVLGYAVLASAGRGDGPAVVVAFAFVYLGLGAI
MSMEG_5167|M.smegmatis_MC2_155 LIAGMLILTAALLFS----------------SLPALIAAAVVSGVGQGMS
MAV_0138|M.avium_104 LAALGYAVAAAAPST---------------LTPALGVPLFVVLGCASGLC
: : . .
Mvan_5855|M.vanbaalenii_PYR-1 FPFEMDTVVSLAGNRLVGTHYGFYNTIVGVGILVGNLATGYLMQAAKR--
Mflv_0900|M.gilvum_PYR-GCK FPFEMDTVVSLADNRLVGTHYGFYNTIVGVGILVGNLATGSLMQLARE--
Mb0872|M.bovis_AF2122/97 FPFEMRAVVALSGDRLVATHYGFYSTIVGVGVLVGNLAIGSLMSAARR--
Rv0849|M.tuberculosis_H37Rv FPFEMRAVVALSGDRLVATHYGFYSTIVGVGVLVGNLAIGSLMSAARR--
MMAR_4767|M.marinum_M FPFEMRTVVVLAEDKLVATHYGFYSTIVGVGILVGNLVVGSLMSVAHR--
MUL_0338|M.ulcerans_Agy99 FPFEMRTVVVLAEDKLVATNYGFYSTIVGVGILVGNLAVGSLMSVAHR--
MAB_1274|M.abscessus_ATCC_1997 FPFEMDTVVRLADNRLVATQYGLYNTIVGIGILAGNLLTGSVFGYSQR--
TH_3412|M.thermoresistible__bu AALGTDIVVGAAPAAKSGSAAAMSETVQELGIAVGVALLGSVTAAVYRSR
MSMEG_5167|M.smegmatis_MC2_155 FSRGLAAIAEKTPPDRRAEVSSTYFVVAYVAISLPVVGEG-LSAQHWG--
MAV_0138|M.avium_104 LREGLIDLEAAAPQRLRGGLTGLFYVVTYIGFGLP------LILASVR--
: : . . .: :.. :
Mvan_5855|M.vanbaalenii_PYR-1 ----------VGAPELLWVLLCAIGAVSALALYRLDRRGLLQPAKSTPDR
Mflv_0900|M.gilvum_PYR-GCK ----------LGRPEFLWVLLTVIGMLSAAALYRLDQRGRLGSTPKAVDD
Mb0872|M.bovis_AF2122/97 ----------LNTDEIVWGGLILVGIVAVAGLRRLDTFT-SGSQNMTGRW
Rv0849|M.tuberculosis_H37Rv ----------LNTDEIVWGGLILVGIVAVAGLRRLDTFT-SGSQNMTGRW
MMAR_4767|M.marinum_M ----------FGADEIVWGGLILIGLATVAGLYQLDRQA-TRADRLSRRH
MUL_0338|M.ulcerans_Agy99 ----------FGADEIVWGGLILIGLATVAGLYQLDRQA-TRAERLSRRH
MAB_1274|M.abscessus_ATCC_1997 ----------RGVPSLLWVSLVVVGLVCAAALFALRRAGLLDRGREVAPA
TH_3412|M.thermoresistible__bu MTGPEGVAEGVGGPDAERLAESLPAAVSVADRVPGEAVRLAQDAFAAGVN
MSMEG_5167|M.smegmatis_MC2_155 ---------LRPAGIAFALAVCVLAVICLVAILVEESRQRRAESAELSAS
MAV_0138|M.avium_104 ----------PGVATAILSGMAVLAVTAAVGRAARLRRDDHRQN------
.
Mvan_5855|M.vanbaalenii_PYR-1 AVAR------------------------
Mflv_0900|M.gilvum_PYR-GCK ATPR------------------------
Mb0872|M.bovis_AF2122/97 AAPR------------------------
Rv0849|M.tuberculosis_H37Rv AAPR------------------------
MMAR_4767|M.marinum_M PPAQLCQQAA------------------
MUL_0338|M.ulcerans_Agy99 PPAQLCQQAA------------------
MAB_1274|M.abscessus_ATCC_1997 ARA-------------------------
TH_3412|M.thermoresistible__bu IAALIGGAAVVVVAVVCATALRHLRPLD
MSMEG_5167|M.smegmatis_MC2_155 T---------------------------
MAV_0138|M.avium_104 ----------------------------