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GFLAQFRSFNRPSRVLMINQFGINVGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTL ADRFGYKPLIVAGCLIRTGGFALLVVAQSLPSVLIAAAATGFAGALFNPAVRAYVAADSGDRKLEAFATF NIFYQAGILLGPLVGLALLTLDFRMTVLGASAVFAVLTAAQLMALPQHLADPDTKNESILQGWKAIVCNR SFLGFAAAMTGAYVLSFQVYLALPIQASLLAPGHQSVLLAAMFAVSGLIAIAGQLRITRWVAAHWRVSRS LVVGAAILAMAFVPLAMVPNAQRFGTGAAVAALLVSASLLAVASAALFPFEMRTVVVLAEDKLVATNYGF YSTIVGVGILVGNLAVGSLMSVAHRFGADEIVWGGLILIGLATVAGLYQLDRQATRAERLSRRHPPAQLC QQAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0338 | - | - | 100% (425) | integral membrane transport protein |
| M. ulcerans Agy99 | MUL_4961 | - | 1e-08 | 25.46% (381) | intergral membrane protein |
| M. ulcerans Agy99 | MUL_3727 | - | 2e-06 | 22.38% (411) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0872 | - | 1e-178 | 74.88% (414) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0900 | - | 1e-150 | 64.60% (404) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0849 | - | 1e-178 | 74.88% (414) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1274 | - | 1e-141 | 62.13% (404) | ABC transporter permease |
| M. marinum M | MMAR_4767 | - | 0.0 | 97.41% (425) | integral membrane transport protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5464 | - | 7e-08 | 23.29% (322) | integral membrane transport protein |
| M. thermoresistible (build 8) | TH_3412 | - | 4e-09 | 29.07% (172) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. vanbaalenii PYR-1 | Mvan_5855 | - | 1e-150 | 66.34% (404) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0338|M.ulcerans_Agy99 ----------------MGFLAQFRSFNRPSRVLMINQFGINVGFYMLMPY
MMAR_4767|M.marinum_M ----------------MGFLAQFRSFNRPSRVLMINQFGINVGFYMLMPY
Mb0872|M.bovis_AF2122/97 ----------------MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPY
Rv0849|M.tuberculosis_H37Rv ----------------MGARAIFRGFNRPSRVLMINQFGINIGFYMLMPY
Mflv_0900|M.gilvum_PYR-GCK ----------------MTLLSGFGSFGWPSRMLMINQFGINLGFYMLMPY
Mvan_5855|M.vanbaalenii_PYR-1 ----------------MNLVSGFRSFGWPSRMLMINQFGINLGFYMLMPY
MAB_1274|M.abscessus_ATCC_1997 MDQAHPRDRPDREEGVIQTLRQFRSFDRPSQILMVNQFAINVGFYMLMPY
TH_3412|M.thermoresistible__bu ----------------MTQCAVRAGAREWAGLGVLAVPTVLLGLDVTVLY
MSMEG_5464|M.smegmatis_MC2_155 --------------------MRTRSPAPLVGLCVFEFLSWGILYYTLPVI
. : :. :
MUL_0338|M.ulcerans_Agy99 LAD-YLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLIVA
MMAR_4767|M.marinum_M LAD-YLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLIVA
Mb0872|M.bovis_AF2122/97 LAD-YLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLIIA
Rv0849|M.tuberculosis_H37Rv LAD-YLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLIIA
Mflv_0900|M.gilvum_PYR-GCK LAG-YLAGPLGLAAWAIGLVLGVRNFSQQGMFIIGGTLADRLGFKPLIVS
Mvan_5855|M.vanbaalenii_PYR-1 LAG-YLAGPLGLAAWAIGLVLGVRNFSQQGMFIIGGTLADRLGYKPLIVA
MAB_1274|M.abscessus_ATCC_1997 LAG-YLAGPLGLAAWMVGLVLGVRNFSQQGMFLVGGTLADRFGYKPLIVA
TH_3412|M.thermoresistible__bu LVLPAVAADLAPSPVQTLWIMDAYGFFIAGFLITMGTLGDRIGRRRLLTI
MSMEG_5464|M.smegmatis_MC2_155 GVR--ITAATGWPPLVVPVVYTTSLLCAAFATPWAGRMVDRHGPRPVMTL
. ::. . .. : . : * : ** * : ::
MUL_0338|M.ulcerans_Agy99 GCLIRTGGFALLVVAQSLPSVLIAAAATGFAGA--LFNPAVRAYVA--AD
MMAR_4767|M.marinum_M GCLIRTGGFALLVVAQSLPSVLIASAATGFAGA--LFNPAVRAYVA--AD
Mb0872|M.bovis_AF2122/97 GCLIRTGGFALLVVAQSLPSVLIAAAATGFAGA--LFNPAVRGYLA--AE
Rv0849|M.tuberculosis_H37Rv GCLIRTGGFALLVVAQSLPSVLIAAAATGFAGA--LFNPAVRGYLA--AE
Mflv_0900|M.gilvum_PYR-GCK GCVLRTAGFGLLVFADSLPAVLVASAATGFAGA--LFNPAVRAYLA--AD
Mvan_5855|M.vanbaalenii_PYR-1 GCVLRTVGFGLLVLADSLPAVLIASAATGFAGA--LFNPAVRAYLA--VD
MAB_1274|M.abscessus_ATCC_1997 GCFLRTAGFAMLAFVGTLPAILIASAATGFAGA--LFNPAVRAYLA--AD
TH_3412|M.thermoresistible__bu GVTAFAGASVLAALAPSAELLIVARALLGVAGA--TLMPSTLSLISNMFV
MSMEG_5464|M.smegmatis_MC2_155 GSLVGAGALVLAGVTGWLPLFAVAWLVVGVAQAGTLYPPAFAAATQWFGT
* : . : .. . :* *.* * *: .
MUL_0338|M.ulcerans_Agy99 SGDRKLEAFATFNIFYQAGILLGPLVG-----------LALLTLDFRMTV
MMAR_4767|M.marinum_M SGDRKLEAFAMFNIFYQAGILLGPLVG-----------LALLTLDFRMTV
Mb0872|M.bovis_AF2122/97 AGERKIEAFAMFNVFYQSGILLGPLVG-----------LVLLALDFRITV
Rv0849|M.tuberculosis_H37Rv AGERKIEAFAMFNVFYQSGILLGPLVG-----------LVLLALDFRITV
Mflv_0900|M.gilvum_PYR-GCK AGPRRLEAFALFNVFYQAGILAGPLVG-----------LALMFVDFKITA
Mvan_5855|M.vanbaalenii_PYR-1 AGPRRLEAFALFNVFYQGGILAGPLVG-----------LALMFVDFRATA
MAB_1274|M.abscessus_ATCC_1997 SGERRVEAFAVFNVFYQAGILFGPIVG-----------LALTAWDFRITC
TH_3412|M.thermoresistible__bu DAAQRALAIGVWATMFAVGMAAGPVVGGALVDRFWWGAAFLLAVPVAAAV
MSMEG_5464|M.smegmatis_MC2_155 VRAWPLTAITLAGGVSSTAFAPLTAALN----------EKLGWQTTLVVL
*: . .: . . * .
MUL_0338|M.ulcerans_Agy99 LGASAVFAVLTAAQLMALPQHLADP--DTKNESILQGWKAIVCNRSFLGF
MMAR_4767|M.marinum_M LGASAVFAVLTAAQLMALPQHLADP--GTKNESILQGWKAIVRNRSFLGF
Mb0872|M.bovis_AF2122/97 LAAAGVFGLLTVAQLVALPQHRADS--EREKTSILQDWRVVVRNRPFLTL
Rv0849|M.tuberculosis_H37Rv LAAAGVFGLLTVAQLVALPQHRADS--EREKTSILQDWRVVVRNRPFLTL
Mflv_0900|M.gilvum_PYR-GCK AAAALVFAVLTVAQLFALPQRAVAP--TPEKTSVLQDWRAVAANRSFLLF
Mvan_5855|M.vanbaalenii_PYR-1 AAAAMVFAVLTVAQLFALPQRTAAP--AEAKTSVLDDWRVVAANRSFLLF
MAB_1274|M.abscessus_ATCC_1997 AVAAAVFAFLTVIQLMALPPNRAESERNADRAPVLTSWRSVVSNKAFLLF
TH_3412|M.thermoresistible__bu LLGARLLPEYADPQAGRLDLRSVALSLLAILAAIYAVKHVAVHGVDGVAV
MSMEG_5464|M.smegmatis_MC2_155 GTGYGVVSTAAAALMLTSRWRRPVREGAEHAEYVTQIVRSAPFRRSRLAL
. :. : . : : : .
MUL_0338|M.ulcerans_Agy99 AAAMTGAYVLSFQVYLALPIQASLLAP---GHQSVLLAAMFAVSGLIAIA
MMAR_4767|M.marinum_M AAAMTGAYVLSFQVYLALPMQASLLAP---GHQSVLVAAMFAVSGLIAIA
Mb0872|M.bovis_AF2122/97 AAAMTGCYALSFQIYLALPMQASILMP---RNQYLLIAAMFAVSGLVAVG
Rv0849|M.tuberculosis_H37Rv AAAMTGCYALSFQIYLALPMQASILMP---RNQYLLIAAMFAVSGLVAVG
Mflv_0900|M.gilvum_PYR-GCK AAAMIGSYVLSFQVYLAMPLQARYLFP---QNDSVVTAMIFVVSGVVAVL
Mvan_5855|M.vanbaalenii_PYR-1 AAAMIGSYVLSFQVYLALPLQARDLFP---GSDSVVTAMIFVVSGLVAVM
MAB_1274|M.abscessus_ATCC_1997 SGAMIGSYVLTFQVYLALPLQAALLTDDK-KSETALVTSIFVVSGLVAIA
TH_3412|M.thermoresistible__bu AACALAAAAATVFVHRQRRLDAPLLDVTLFADRAFTAALTVLLIGLIGVG
MSMEG_5464|M.smegmatis_MC2_155 AMTALGLYAVTLNVIPLLTELGFGYHS---------AAIVFGLIGVGQVF
: . . :. : . : . : *: :
MUL_0338|M.ulcerans_Agy99 G----------------QLRITRWVAAHWRVSRSLVVGAAILAMAFVPLA
MMAR_4767|M.marinum_M G----------------QLRITRWFAAHWRVSRSLVVGAAILAIAFVPLA
Mb0872|M.bovis_AF2122/97 G----------------QLRITRWFAVRWGAERSLVVGATILAASFIPVA
Rv0849|M.tuberculosis_H37Rv G----------------QLRITRWFAVRWGAERSLVVGATILAASFIPVA
Mflv_0900|M.gilvum_PYR-GCK G----------------QMRITRWFGRRWGSGRSLAIGMLILALSFLPLI
Mvan_5855|M.vanbaalenii_PYR-1 G----------------QMRITRWFAKRWGAGRSLMIGMLILAVSFVPLM
MAB_1274|M.abscessus_ATCC_1997 G----------------QVRLTGWLSARFGPSRSLVLGMLVIGTAFVPLV
TH_3412|M.thermoresistible__bu GTMYLVTQFLQLVEGLTPVRAGWWMGPPALAMFVAAIGAPLIARRVRPGV
MSMEG_5464|M.smegmatis_MC2_155 G------------------RVLYLPLRRLGTPRARTTAQVAASTAGMGIL
* * . .
MUL_0338|M.ulcerans_Agy99 MVPNAQ----------RFGTGAAVAALLVSASLLAVASAALFPFEMR-TV
MMAR_4767|M.marinum_M MVPNAQ----------RFGTGAAVAALLVSASLLAVASAALFPFEMR-TV
Mb0872|M.bovis_AF2122/97 VIPNGQ----------RFGVAVAVMALVLSASLLAVASAALFPFEMR-AV
Rv0849|M.tuberculosis_H37Rv VIPNGQ----------RFGVAVAVMALVLSASLLAVASAALFPFEMR-AV
Mflv_0900|M.gilvum_PYR-GCK ALPDDE----------RAGRVAAATALLIATAVLAVGSAAVFPFEMD-TV
Mvan_5855|M.vanbaalenii_PYR-1 ALPDDT----------RAGRVAAATALLGATAVLAVGSAAVFPFEMD-TV
MAB_1274|M.abscessus_ATCC_1997 LLPTAA----------SAGQLAAIAALLFSAALLAVGTIATFPFEMD-TV
TH_3412|M.thermoresistible__bu VMAATLGVSVLGYAVLASAGRGDGPAVVVAFAFVYLGLGAIAALGTD-IV
MSMEG_5464|M.smegmatis_MC2_155 AVVTAP------------------LALAASAAMFAGAARGTHTLSVANAV
: *: : :.. . . .: *
MUL_0338|M.ulcerans_Agy99 VVLAEDKLVATNYGFYSTIVGVGILVGNLAVGSLMSVAHR----------
MMAR_4767|M.marinum_M VVLAEDKLVATHYGFYSTIVGVGILVGNLVVGSLMSVAHR----------
Mb0872|M.bovis_AF2122/97 VALSGDRLVATHYGFYSTIVGVGVLVGNLAIGSLMSAARR----------
Rv0849|M.tuberculosis_H37Rv VALSGDRLVATHYGFYSTIVGVGVLVGNLAIGSLMSAARR----------
Mflv_0900|M.gilvum_PYR-GCK VSLADNRLVGTHYGFYNTIVGVGILVGNLATGSLMQLARE----------
Mvan_5855|M.vanbaalenii_PYR-1 VSLAGNRLVGTHYGFYNTIVGVGILVGNLATGYLMQAAKR----------
MAB_1274|M.abscessus_ATCC_1997 VRLADNRLVATQYGLYNTIVGIGILAGNLLTGSVFGYSQR----------
TH_3412|M.thermoresistible__bu VGAAPAAKSGSAAAMSETVQELGIAVGVALLGSVTAAVYRSRMTGPEGVA
MSMEG_5464|M.smegmatis_MC2_155 TDRWGAESYATILGRFHRPVAIAMALG-PATGSAIAAALG----------
. .: . :.: * *
MUL_0338|M.ulcerans_Agy99 --FGADEIVWGGLILIGLATVAGLYQLDRQATRAERLSRRHPPAQLCQQA
MMAR_4767|M.marinum_M --FGADEIVWGGLILIGLATVAGLYQLDRQATRADRLSRRHPPAQLCQQA
Mb0872|M.bovis_AF2122/97 --LNTDEIVWGGLILVGIVAVAGLRRLDTFTSGSQNMTGRWAAPR-----
Rv0849|M.tuberculosis_H37Rv --LNTDEIVWGGLILVGIVAVAGLRRLDTFTSGSQNMTGRWAAPR-----
Mflv_0900|M.gilvum_PYR-GCK --LGRPEFLWVLLTVIGMLSAAALYRLDQRGRLGSTPKAVDDATPR----
Mvan_5855|M.vanbaalenii_PYR-1 --VGAPELLWVLLCAIGAVSALALYRLDRRGLLQPAKSTPDRAVAR----
MAB_1274|M.abscessus_ATCC_1997 --RGVPSLLWVSLVVVGLVCAAALFALRRAGLLDRGREVAPAARA-----
TH_3412|M.thermoresistible__bu EGVGGPDAERLAESLPAAVSVADRVPGEAVRLAQDAFAAGVNIAALIGGA
MSMEG_5464|M.smegmatis_MC2_155 -------SYRTAAALFAVLGGLAILTARRS--------------------
.
MUL_0338|M.ulcerans_Agy99 A-------------------
MMAR_4767|M.marinum_M A-------------------
Mb0872|M.bovis_AF2122/97 --------------------
Rv0849|M.tuberculosis_H37Rv --------------------
Mflv_0900|M.gilvum_PYR-GCK --------------------
Mvan_5855|M.vanbaalenii_PYR-1 --------------------
MAB_1274|M.abscessus_ATCC_1997 --------------------
TH_3412|M.thermoresistible__bu AVVVVAVVCATALRHLRPLD
MSMEG_5464|M.smegmatis_MC2_155 --------------------