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MDQAHPRDRPDREEGVIQTLRQFRSFDRPSQILMVNQFAINVGFYMLMPYLAGYLAGPLGLAAWMVGLVL GVRNFSQQGMFLVGGTLADRFGYKPLIVAGCFLRTAGFAMLAFVGTLPAILIASAATGFAGALFNPAVRA YLAADSGERRVEAFAVFNVFYQAGILFGPIVGLALTAWDFRITCAVAAAVFAFLTVIQLMALPPNRAESE RNADRAPVLTSWRSVVSNKAFLLFSGAMIGSYVLTFQVYLALPLQAALLTDDKKSETALVTSIFVVSGLV AIAGQVRLTGWLSARFGPSRSLVLGMLVIGTAFVPLVLLPTAASAGQLAAIAALLFSAALLAVGTIATFP FEMDTVVRLADNRLVATQYGLYNTIVGIGILAGNLLTGSVFGYSQRRGVPSLLWVSLVVVGLVCAAALFA LRRAGLLDRGREVAPAARA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1274 | - | - | 100% (439) | ABC transporter permease |
| M. abscessus ATCC 19977 | MAB_0450c | - | 0.0 | 96.44% (421) | ABC transporter |
| M. abscessus ATCC 19977 | MAB_4615 | - | 2e-11 | 28.04% (403) | major facilitator transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0872 | - | 1e-137 | 59.09% (396) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0900 | - | 1e-145 | 63.48% (408) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0849 | - | 1e-137 | 59.09% (396) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01562 | - | 6e-07 | 28.03% (132) | putative transmembrane efflux protein |
| M. marinum M | MMAR_4767 | - | 1e-142 | 61.43% (420) | integral membrane transport protein |
| M. avium 104 | MAV_3974 | - | 8e-07 | 19.55% (358) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_6225 | - | 1e-08 | 21.82% (385) | proton antiporter efflux pump |
| M. thermoresistible (build 8) | TH_3412 | - | 1e-09 | 23.14% (389) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0338 | - | 1e-141 | 62.13% (404) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_5855 | - | 1e-144 | 63.79% (417) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0872|M.bovis_AF2122/97 --------------------------------------------MGARAI
Rv0849|M.tuberculosis_H37Rv --------------------------------------------MGARAI
MMAR_4767|M.marinum_M --------------------------------------------MGFLAQ
MUL_0338|M.ulcerans_Agy99 --------------------------------------------MGFLAQ
Mflv_0900|M.gilvum_PYR-GCK --------------------------------------------MTLLSG
Mvan_5855|M.vanbaalenii_PYR-1 --------------------------------------------MNLVSG
MAB_1274|M.abscessus_ATCC_1997 ----------------------------MDQAHPRDRPDREEGVIQTLRQ
MSMEG_6225|M.smegmatis_MC2_155 -------------------------------------MSTCIEGTPSTTR
TH_3412|M.thermoresistible__bu -------------------------------------------MTQCAVR
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
MAV_3974|M.avium_104 --------------------------------------------------
Mb0872|M.bovis_AF2122/97 FRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGV
Rv0849|M.tuberculosis_H37Rv FRGFNRPSRVLMINQFGINIGFYMLMPYLADYLAGPLGLAAWAVGLVMGV
MMAR_4767|M.marinum_M FRSFNRPSRVLMINQFGINVGFYMLMPYLADYLAGPLGLAAWAVGLVMGV
MUL_0338|M.ulcerans_Agy99 FRSFNRPSRVLMINQFGINVGFYMLMPYLADYLAGPLGLAAWAVGLVMGV
Mflv_0900|M.gilvum_PYR-GCK FGSFGWPSRMLMINQFGINLGFYMLMPYLAGYLAGPLGLAAWAIGLVLGV
Mvan_5855|M.vanbaalenii_PYR-1 FRSFGWPSRMLMINQFGINLGFYMLMPYLAGYLAGPLGLAAWAIGLVLGV
MAB_1274|M.abscessus_ATCC_1997 FRSFDRPSQILMVNQFAINVGFYMLMPYLAGYLAGPLGLAAWMVGLVLGV
MSMEG_6225|M.smegmatis_MC2_155 TPTRAWVALAVLALPVLLIAIDNTVLAFALPLIAEDFRPSATTQLWIVDV
TH_3412|M.thermoresistible__bu AGAREWAGLGVLAVPTVLLGLDVTVLYLVLPAVAADLAPSPVQTLWIMDA
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
MAV_3974|M.avium_104 -----------------MVALGYGVISPALPTFARSFGVSIKAVTFLVTV
: : . : : : .
Mb0872|M.bovis_AF2122/97 RNFSQQGMFFVGGTLADRFGYKPLIIAGCLIRTGGFALLVVAQSLPSVLI
Rv0849|M.tuberculosis_H37Rv RNFSQQGMFFVGGTLADRFGYKPLIIAGCLIRTGGFALLVVAQSLPSVLI
MMAR_4767|M.marinum_M RNFSQQGMFFVGGTLADRFGYKPLIVAGCLIRTGGFALLVVAQSLPSVLI
MUL_0338|M.ulcerans_Agy99 RNFSQQGMFFVGGTLADRFGYKPLIVAGCLIRTGGFALLVVAQSLPSVLI
Mflv_0900|M.gilvum_PYR-GCK RNFSQQGMFIIGGTLADRLGFKPLIVSGCVLRTAGFGLLVFADSLPAVLV
Mvan_5855|M.vanbaalenii_PYR-1 RNFSQQGMFIIGGTLADRLGYKPLIVAGCVLRTVGFGLLVLADSLPAVLI
MAB_1274|M.abscessus_ATCC_1997 RNFSQQGMFLVGGTLADRFGYKPLIVAGCFLRTAGFAMLAFVGTLPAILI
MSMEG_6225|M.smegmatis_MC2_155 YSLVLAALLVAMGSLGDRLGRRRLLLIGGAGFAVVSALAAFAPSAELLVG
TH_3412|M.thermoresistible__bu YGFFIAGFLITMGTLGDRIGRRRLLTIGVTAFAGASVLAALAPSAELLIV
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
MAV_3974|M.avium_104 FSLSRLCFAPISGLLTERLGERRIYIGGLLIVAVSTAACAFSQAYWQLML
: : * * : :* : * : .. ::
Mb0872|M.bovis_AF2122/97 AAAATGFAGALFNPAVRGYLA--AEAGERKIEAFAMFNVFYQSGILLGPL
Rv0849|M.tuberculosis_H37Rv AAAATGFAGALFNPAVRGYLA--AEAGERKIEAFAMFNVFYQSGILLGPL
MMAR_4767|M.marinum_M ASAATGFAGALFNPAVRAYVA--ADSGDRKLEAFAMFNIFYQAGILLGPL
MUL_0338|M.ulcerans_Agy99 AAAATGFAGALFNPAVRAYVA--ADSGDRKLEAFATFNIFYQAGILLGPL
Mflv_0900|M.gilvum_PYR-GCK ASAATGFAGALFNPAVRAYLA--ADAGPRRLEAFALFNVFYQAGILAGPL
Mvan_5855|M.vanbaalenii_PYR-1 ASAATGFAGALFNPAVRAYLA--VDAGPRRLEAFALFNVFYQGGILAGPL
MAB_1274|M.abscessus_ATCC_1997 ASAATGFAGALFNPAVRAYLA--ADSGERRVEAFAVFNVFYQAGILFGPI
MSMEG_6225|M.smegmatis_MC2_155 ARALLGVFGAMLMPSTLSLIRNIFTDASARRLAIAIWASCFTAGSALGPI
TH_3412|M.thermoresistible__bu ARALLGVAGATLMPSTLSLISNMFVDAAQRALAIGVWATMFAVGMAAGPV
MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
MAV_3974|M.avium_104 CRVFSGVGSTMFYVSALGLMIH-ISPADARGRIAGLFTTSFMVGAVGGPA
. *. .: : . : . : . : * *
Mb0872|M.bovis_AF2122/97 VG-LVLLALDFRITVLAAAGVFGLLTVAQLVALPQHRADSER--EKTSIL
Rv0849|M.tuberculosis_H37Rv VG-LVLLALDFRITVLAAAGVFGLLTVAQLVALPQHRADSER--EKTSIL
MMAR_4767|M.marinum_M VG-LALLTLDFRMTVLGASAVFAVLTAAQLMALPQHLADPGT--KNESIL
MUL_0338|M.ulcerans_Agy99 VG-LALLTLDFRMTVLGASAVFAVLTAAQLMALPQHLADPDT--KNESIL
Mflv_0900|M.gilvum_PYR-GCK VG-LALMFVDFKITAAAAALVFAVLTVAQLFALPQRAVAPTP--EKTSVL
Mvan_5855|M.vanbaalenii_PYR-1 VG-LALMFVDFRATAAAAAMVFAVLTVAQLFALPQRTAAPAE--AKTSVL
MAB_1274|M.abscessus_ATCC_1997 VG-LALTAWDFRITCAVAAAVFAFLTVIQLMALPPNRAESERNADRAPVL
MSMEG_6225|M.smegmatis_MC2_155 VGGALLEHFHWGAVFLVAVPILLPLLVLGPRLVPESRDPNPGPFDPVSIV
TH_3412|M.thermoresistible__bu VGGALVDRFWWGAAFLLAVPVAA-AVLLGARLLPEYADPQAGRLDLRSVA
MLBr_01562|M.leprae_Br4923 VG-GALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAIL
MAV_3974|M.avium_104 VG-GLAAGWGLTAPFVVYGVAMLGVALVLFLGLRNSALAAPPPPTRSTVT
** : .:
Mb0872|M.bovis_AF2122/97 QDWRVVVR--------------------------NRPFLTLAAAMTGCYA
Rv0849|M.tuberculosis_H37Rv QDWRVVVR--------------------------NRPFLTLAAAMTGCYA
MMAR_4767|M.marinum_M QGWKAIVR--------------------------NRSFLGFAAAMTGAYV
MUL_0338|M.ulcerans_Agy99 QGWKAIVC--------------------------NRSFLGFAAAMTGAYV
Mflv_0900|M.gilvum_PYR-GCK QDWRAVAA--------------------------NRSFLLFAAAMIGSYV
Mvan_5855|M.vanbaalenii_PYR-1 DDWRVVAA--------------------------NRSFLLFAAAMIGSYV
MAB_1274|M.abscessus_ATCC_1997 TSWRSVVS--------------------------NKAFLLFSGAMIGSYV
MSMEG_6225|M.smegmatis_MC2_155 LSFTTMLPIVWAVKTAAHDGLSAAAAAAFAVGIVSGALFVRRQNRSATPM
TH_3412|M.thermoresistible__bu LSLLAILAAIYAVKHVAVHGVDGVAVAACALAAAAATVFVHRQRRLDAPL
MLBr_01562|M.leprae_Br4923 ATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPV
MAV_3974|M.avium_104 MREALRVR-------------------------------AYQSALLSNFA
Mb0872|M.bovis_AF2122/97 LSFQIYLALPMQASILMP--RNQYLLIAAMFAVSGLVAVGGQLRITR--W
Rv0849|M.tuberculosis_H37Rv LSFQIYLALPMQASILMP--RNQYLLIAAMFAVSGLVAVGGQLRITR--W
MMAR_4767|M.marinum_M LSFQVYLALPMQASLLAP--GHQSVLVAAMFAVSGLIAIAGQLRITR--W
MUL_0338|M.ulcerans_Agy99 LSFQVYLALPIQASLLAP--GHQSVLLAAMFAVSGLIAIAGQLRITR--W
Mflv_0900|M.gilvum_PYR-GCK LSFQVYLAMPLQARYLFP--QNDSVVTAMIFVVSGVVAVLGQMRITR--W
Mvan_5855|M.vanbaalenii_PYR-1 LSFQVYLALPLQARDLFP--GSDSVVTAMIFVVSGLVAVMGQMRITR--W
MAB_1274|M.abscessus_ATCC_1997 LTFQVYLALPLQAALLTDDKKSETALVTSIFVVSGLVAIAGQVRLTG--W
MSMEG_6225|M.smegmatis_MC2_155 LDIGLFKVMPFTSSILANFLSIIGLIGFIFFISQHLQLVLGLSPLTAGLV
TH_3412|M.thermoresistible__bu LDVTLFADRAFTAALTVLLIGLIGVGGTMYLVTQFLQLVEGLTPVRAGWW
MLBr_01562|M.leprae_Br4923 VPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAGIG
MAV_3974|M.avium_104 TGWSAFGLRMALVPLFVS----DVMGRGIGTIGVVLAAFAGGNALAV---
: : . * :
Mb0872|M.bovis_AF2122/97 FAVRWGAERSLVVGATILAASFIPVAVIPNGQ-------------RFGVA
Rv0849|M.tuberculosis_H37Rv FAVRWGAERSLVVGATILAASFIPVAVIPNGQ-------------RFGVA
MMAR_4767|M.marinum_M FAAHWRVSRSLVVGAAILAIAFVPLAMVPNAQ-------------RFGTG
MUL_0338|M.ulcerans_Agy99 VAAHWRVSRSLVVGAAILAMAFVPLAMVPNAQ-------------RFGTG
Mflv_0900|M.gilvum_PYR-GCK FGRRWGSGRSLAIGMLILALSFLPLIALPDDE-------------RAGRV
Mvan_5855|M.vanbaalenii_PYR-1 FAKRWGAGRSLMIGMLILAVSFVPLMALPDDT-------------RAGRV
MAB_1274|M.abscessus_ATCC_1997 LSARFGPSRSLVLGMLVIGTAFVPLVLLPTAA-------------SAGQL
MSMEG_6225|M.smegmatis_MC2_155 TLPGAVVSMIAGLAVVKAAKRFAPDTLMVTGLVFVAVGFLM--ILLFRHN
TH_3412|M.thermoresistible__bu MGPPALAMFVAAIGAPLIARRVRPGVVMAATLGVSVLGYAV--LASAGR-
MLBr_01562|M.leprae_Br4923 FIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRGV
MAV_3974|M.avium_104 -VPSGYLSDRMGRRTLLIVGLVTSGAATVWLG----------------FV
. .
Mb0872|M.bovis_AF2122/97 VAVMALVLSASLLAVASAALFPFEMRAVVALSG-DRLVATHYGFYSTIVG
Rv0849|M.tuberculosis_H37Rv VAVMALVLSASLLAVASAALFPFEMRAVVALSG-DRLVATHYGFYSTIVG
MMAR_4767|M.marinum_M AAVAALLVSASLLAVASAALFPFEMRTVVVLAE-DKLVATHYGFYSTIVG
MUL_0338|M.ulcerans_Agy99 AAVAALLVSASLLAVASAALFPFEMRTVVVLAE-DKLVATNYGFYSTIVG
Mflv_0900|M.gilvum_PYR-GCK AAATALLIATAVLAVGSAAVFPFEMDTVVSLAD-NRLVGTHYGFYNTIVG
Mvan_5855|M.vanbaalenii_PYR-1 AAATALLGATAVLAVGSAAVFPFEMDTVVSLAG-NRLVGTHYGFYNTIVG
MAB_1274|M.abscessus_ATCC_1997 AAIAALLFSAALLAVGTIATFPFEMDTVVRLAD-NRLVATQYGLYNTIVG
MSMEG_6225|M.smegmatis_MC2_155 LTVAAIIASFVVLELGVGVSQTVSNDTIVASVP-AAKSGAASAVSETAYE
TH_3412|M.thermoresistible__bu GDGPAVVVAFAFVYLGLGAIAALGTDIVVGAAP-AAKSGSAAAMSETVQE
MLBr_01562|M.leprae_Br4923 PYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVG-FDRIGPVSAIALMLQS
MAV_3974|M.avium_104 ASLPVFLVAAGVVGVVTGIYMSPLQAAVADILGNEARAGLPVATVQMMSD
.: . . : . .
Mb0872|M.bovis_AF2122/97 VGVLVGNLAIGSLMSAARRL---------------NTDEIVWGGLILVGI
Rv0849|M.tuberculosis_H37Rv VGVLVGNLAIGSLMSAARRL---------------NTDEIVWGGLILVGI
MMAR_4767|M.marinum_M VGILVGNLVVGSLMSVAHRF---------------GADEIVWGGLILIGL
MUL_0338|M.ulcerans_Agy99 VGILVGNLAVGSLMSVAHRF---------------GADEIVWGGLILIGL
Mflv_0900|M.gilvum_PYR-GCK VGILVGNLATGSLMQLAREL---------------GRPEFLWVLLTVIGM
Mvan_5855|M.vanbaalenii_PYR-1 VGILVGNLATGYLMQAAKRV---------------GAPELLWVLLCAIGA
MAB_1274|M.abscessus_ATCC_1997 IGILAGNLLTGSVFGYSQRR---------------GVPSLLWVSLVVVGL
MSMEG_6225|M.smegmatis_MC2_155 LGAVVGTATLGTIFTAFYRSNVDVPAGLTPEQTGAAAESIGGAAAVAADL
TH_3412|M.thermoresistible__bu LGIAVGVALLGSVTAAVYRSRMTGPEGVAEGVGGPDAERLAESLPAAVSV
MLBr_01562|M.leprae_Br4923 LGGPLVLAVIQAVITSRTLYLGG---------TTGPVKFMNDAQLRALDH
MAV_3974|M.avium_104 LGAIVGSMAVGWAAEQIGYG----------------WGFFISGVVLLIAA
:* :
Mb0872|M.bovis_AF2122/97 VAVAGLRRLDTFT-SGSQNMTGRWAAPR---------------------
Rv0849|M.tuberculosis_H37Rv VAVAGLRRLDTFT-SGSQNMTGRWAAPR---------------------
MMAR_4767|M.marinum_M ATVAGLYQLDRQA-TRADRLSRRHPPAQLCQQAA---------------
MUL_0338|M.ulcerans_Agy99 ATVAGLYQLDRQA-TRAERLSRRHPPAQLCQQAA---------------
Mflv_0900|M.gilvum_PYR-GCK LSAAALYRLDQRGRLGSTPKAVDDATPR---------------------
Mvan_5855|M.vanbaalenii_PYR-1 VSALALYRLDRRGLLQPAKSTPDRAVAR---------------------
MAB_1274|M.abscessus_ATCC_1997 VCAAALFALRRAGLLDRGREVAPAARA----------------------
MSMEG_6225|M.smegmatis_MC2_155 PAATATQLLDSARAAFDSGIAPTAVIAAMLVLAAAAVVGVAFRR-----
TH_3412|M.thermoresistible__bu ADRVPGEAVRLAQDAFAAGVNIAALIGGAAVVVVAVVCATALRHLRPLD
MLBr_01562|M.leprae_Br4923 GYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL----
MAV_3974|M.avium_104 VGWVMAPETRTATELEADLMAASRTSSRCEQQL----------------