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M. smegmatis MC2 155 MSMEG_5167 (-)

annotation: major facilitator superfamily protein MFS_1
coordinates: 5268527 - 5269732
length: 401

VPHTRRFSFALLAYAFAAIMVGTTLPTPMYALYAEHMNFAVLTTTVIYATYAGGVLFALLLFGRWSDAIG
RRPMLLAGVAAALISAGVFLMADSVPVLLIGRIFSGLSAGIFTGTATAAVIEAAPPAWRTRAAAVATVAN
IGGLGTGPLLAGLLVEYAPRPLHLSFVVHIVMAVLAGAAVFAVPETSSRSGSIGLQRLSVPPEVRTVFVI
AAIAAFAGFAVTGMYTAVAPSFLSNVIGVDNHAVAGAVACSIFAASAVTQVLANRVQPGRAVAVGCAILI
AGMLILTAALLFSSLPALIAAAVVSGVGQGMSFSRGLAAIAEKTPPDRRAEVSSTYFVVAYVAISLPVVG
EGLSAQHWGLRPAGIAFALAVCVLAVICLVAILVEESRQRRAESAELSAST
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5167--100% (401)major facilitator superfamily protein MFS_1
M. smegmatis MC2 155MSMEG_3373-1e-4932.14% (392) major facilitator superfamily protein MFS_1
M. smegmatis MC2 155MSMEG_0534-1e-2927.47% (364) permease, major facilitator family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3755-1e-1125.48% (361) hypothetical protein Mb3755
M. gilvum PYR-GCKMflv_1450-6e-5230.98% (397) major facilitator transporter
M. tuberculosis H37RvRv3728-1e-1125.48% (361) hypothetical protein Rv3728
M. leprae Br4923MLBr_01562-1e-0725.61% (285) putative transmembrane efflux protein
M. abscessus ATCC 19977MAB_1299c-1e-14061.68% (394) multidrug ABC transporter
M. marinum MMMAR_1306-6e-1329.86% (278) transmembrane transport protein
M. avium 104MAV_0138-3e-2728.69% (359) transporter, major facilitator family protein
M. thermoresistible (build 8)TH_0476-1e-15872.16% (388) major facilitator superfamily protein MFS_1
M. ulcerans Agy99MUL_3590-8e-1026.26% (396) transmembrane transport protein
M. vanbaalenii PYR-1Mvan_5329-7e-5231.14% (395) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------MPHTRR
TH_0476|M.thermoresistible__bu      -----------------------------------------------VRR
MAB_1299c|M.abscessus_ATCC_199      -------------------------------------------MIARLRR
Mflv_1450|M.gilvum_PYR-GCK          -------------------------------------MVAIDRSIGETQR
Mvan_5329|M.vanbaalenii_PYR-1       -------------------------------------MVAFDRSIPDTQR
Mb3755|M.bovis_AF2122/97            --------------MHTVATNNAAPVIAAGPVGPSRRRRRVHAPLTRRRQ
Rv3728|M.tuberculosis_H37Rv         --------------MHTVATNNAAPVIAAGPVGPSRRRRRVHAPLTRRRQ
MMAR_1306|M.marinum_M               -----MSGVSISSFEKVTSRHSKRPGATPARTHLAGHARKGFANLTHRRQ
MUL_3590|M.ulcerans_Agy99           -------------------------------MHLSAPAER--SALTSRRQ
MLBr_01562|M.leprae_Br4923          MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
MAV_0138|M.avium_104                ------------------------------MMSSNVRAARNRPGRTDPQP
                                                                                    : 

MSMEG_5167|M.smegmatis_MC2_155      -FSFALLAYAFA------AIMVGTTLPTPMYALYAEHMNFAVLTTTVIYA
TH_0476|M.thermoresistible__bu      -FAFPLLAYAFA------AVMVGTTVPTPMYAVYAERLGFGVLTTTVVFA
MAB_1299c|M.abscessus_ATCC_199      SAAFVLLAFSFS------AVMIGTTMPTPMYALYSQQMHFSVLTTTVVYA
Mflv_1450|M.gilvum_PYR-GCK          -WAYPLLLVLSG------VALGVSGLPAPLYGIYETNWHLSPLATTIVFA
Mvan_5329|M.vanbaalenii_PYR-1       -WAYPLLLVLSG------VALGVSGLPAPLYGIYETNWHLSPLATTVVFA
Mb3755|M.bovis_AF2122/97            PSSSAVLLVAAFG--AFLAFLDSTIVNVAFPDIQRHFHS-DISDLSWMLN
Rv3728|M.tuberculosis_H37Rv         PSSSAVLLVAAFG--AFLAFLDSTIVNVAFPDIQRHFHS-DISDLSWMLN
MMAR_1306|M.marinum_M               PSSAAVLLVAAFG--AFLAFLDSTIVNIAFPDIQKSFPSYDLGSLSWILN
MUL_3590|M.ulcerans_Agy99           PSATAVLLVASFG--AFLAFLDSTIVNIAFPHIQRSFPSYDISSLSWILN
MLBr_01562|M.leprae_Br4923          PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQN-ELSLSDAGRSWGIT
MAV_0138|M.avium_104                PTGAPLFVGVLG---LLLATGWVANHFVGLMPAISDRDHLATTTLDGIFG
                                      .  :            .    :     :                    

MSMEG_5167|M.smegmatis_MC2_155      TYAGGVLFALLLFGRWSDAIGRRPMLLAGVAAALISAGVFLMADSVPVLL
TH_0476|M.thermoresistible__bu      GYTAGVLFALVVFGRWSDALGRRPMLLAGVGCAIVSALVFLIAGSVPQLI
MAB_1299c|M.abscessus_ATCC_199      TYAAGVLFALLMFGGWSDVLGRRPLLLTGAGFAILSSVIFLFVDSVPLLL
Mflv_1450|M.gilvum_PYR-GCK          VYAVAALAAVLVSGRISDVVGRKPVLLGALVALLIGLGVFLIADSMAMLL
Mvan_5329|M.vanbaalenii_PYR-1       VYAVAALAAVLVSGRISDVVGRKPVLVGALVALLIGLGVFLIADSMAMLL
Mb3755|M.bovis_AF2122/97            AYNIVFAAFLVAAGRLADLMGRKRVFILGVALFTVASGLCAIAESVGELV
Rv3728|M.tuberculosis_H37Rv         AYNIVFAAFLVAAGRLADLMGRKRVFILGVALFTVASGLCAIAESVGELV
MMAR_1306|M.marinum_M               AYNIVFAAFLVAAGRMADLLGRRRTFTFGVVIFTIASGLCAVAGSVEWLV
MUL_3590|M.ulcerans_Agy99           GYNIVFAAFLVASGRLADVLGRKRMFVFGVVLFTIASGLCAVAGDVEQLV
MLBr_01562|M.leprae_Br4923          AYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLV
MAV_0138|M.avium_104                IYALGLLPGLLVGGRTSDALGRRPVALTGSAAALVGTVAMLLSQHSPALF
                                     *       ::  *  .* :**:     .     :.     .      *.

MSMEG_5167|M.smegmatis_MC2_155      IGRIFSGLSAGIFTGTATAAVIEAAP-PAWRTRAAAVATVANIGGLGTGP
TH_0476|M.thermoresistible__bu      AARFVSGMSAGIFTGTATAAVIEAAP-ERRRSRAAAVATVANIGGLGAGP
MAB_1299c|M.abscessus_ATCC_199      VARIVSGLSAGFFTGAATVAVIESAP-ETWRGRAAAVATVANTGGLGLGP
Mflv_1450|M.gilvum_PYR-GCK          LARAIHGVAVGSIVVAGAAALLDLRP-DHG-VRVGQLSGVAFNIGMTIAI
Mvan_5329|M.vanbaalenii_PYR-1       LARTIHGAAVGSIVVAGAAALLDLRP-DHG-VRAGQLSGVSFNIGMTVAI
Mb3755|M.bovis_AF2122/97            AFRVLQGIGAAVLVPASLGLVVEAFP-AERRAHGVNLWGAAGAIAAGLGP
Rv3728|M.tuberculosis_H37Rv         AFRVLQGIGAAVLVPASLGLVVEAFP-AERRAHGVNLWGAAGAIAAGLGP
MMAR_1306|M.marinum_M               AFRVLQGIGAAVLVPASLALVVEGFE-PARRAHAVGLWGAAAAIASGLGP
MUL_3590|M.ulcerans_Agy99           GFRVLQGIGAAVLVPASLALVVEGFD-ASHRAHAVGLWGAAAAVASGLGP
MLBr_01562|M.leprae_Br4923          IARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGL
MAV_0138|M.avium_104                AGRLIVGLGVGLAISAGTAWASDLRG-----PAGAATAGAVLTAGFAVGP
                                      * . * . .    :.                      .    .   . 

MSMEG_5167|M.smegmatis_MC2_155      LLAGLLVEYAPRPLHLSFVVHIVMAVLAGAAVFAV--PETSSRSGS----
TH_0476|M.thermoresistible__bu      LLAGILVQYAPWPLHLTFWVHIVLMVLAAAAIAVA--PETSPRTGR----
MAB_1299c|M.abscessus_ATCC_199      LLAGVLVQYAPWPTHLAFVVHIGLVSIAVAALLFV--PETAPKHGK----
Mflv_1450|M.gilvum_PYR-GCK          FGSALLAQYAPHPLRTPYAVVAVICLIVGVGVLALREPHTARTRGP----
Mvan_5329|M.vanbaalenii_PYR-1       LGSALLAQYAPHPLRTPYAVVAVICLVVGVGVLALREPHTARTRGP----
Mb3755|M.bovis_AF2122/97            PIGGALIEADGWRWVFLVNLPLGVFAVLAARRALVENRAAGRRRVPDVRG
Rv3728|M.tuberculosis_H37Rv         PIGGALIEADGWRWVFLVNLPLGVFAVLAARRALVENRAAGRRRVPDVRG
MMAR_1306|M.marinum_M               PIGGMLVDWASWRWVFLVNIPLGVVAVLATSRALVESRAAGRRRKPDLRG
MUL_3590|M.ulcerans_Agy99           PVGGMLVEASSWRLVFLVNIPLGIVAVLVAGRVLTESRASGRRRVPDLRG
MLBr_01562|M.leprae_Br4923          VVGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAG--
MAV_0138|M.avium_104                FAGGVLAWAGPSGVRASFALAAAILALAAFAVVAAPQPSPVTAPADPD--
                                      .. *             :   :  :                       

MSMEG_5167|M.smegmatis_MC2_155      -------IGLQRLSVP--------PEVRTVFVIAAIAAFAGFAVTG----
TH_0476|M.thermoresistible__bu      -------LGVQRLSLP--------PQVRKVFAIASLAAFAGFAVTG----
MAB_1299c|M.abscessus_ATCC_199      -------LGRQRLSLP--------PQVRATFAAAATAGFAGFAALG----
Mflv_1450|M.gilvum_PYR-GCK          -------IRIARPAVP--------AEIRADFWFSALGAMASWSVLG----
Mvan_5329|M.vanbaalenii_PYR-1       -------IRIARPAVP--------AEIRADFWFSALGAMASWSVLG----
Mb3755|M.bovis_AF2122/97            AVLLAFALGLLTLGLIKGPDWGWASLPTSGSLLAAAVAMVGFVMSSRHHP
Rv3728|M.tuberculosis_H37Rv         AVLLAFALGLLTLGLIKGPDWGWASLPTSGSLLAAAVAMVGFVMSSRHHP
MMAR_1306|M.marinum_M               ATLLAGALGLLTLALVKGPDWGWVSVPTLAVFAASAITLVGFVLSSMAAP
MUL_3590|M.ulcerans_Agy99           AMLLGVALGLMTLGLVKGPEWGWISTATIGSFVASSVALVAFVASSRSHP
MLBr_01562|M.leprae_Br4923          AILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAE
MAV_0138|M.avium_104                --------GEETADAAP-------QGISRALSWAMPLAPWVFASAT----
                                                                             :        

MSMEG_5167|M.smegmatis_MC2_155      ------------------MYTAVAPS-----------FLSNVIGVDNHAV
TH_0476|M.thermoresistible__bu      ------------------LFTAVAPS-----------FLAEVIGVRNHAV
MAB_1299c|M.abscessus_ATCC_199      ------------------SFTAVAPG-----------FLSGVLGIDNHAV
Mflv_1450|M.gilvum_PYR-GCK          ------------------VLLSLYPS-----------LAAHHTHIDNLVF
Mvan_5329|M.vanbaalenii_PYR-1       ------------------VLLSLYPS-----------LAARQTHIDNLVF
Mb3755|M.bovis_AF2122/97            APMVEPTLLRIQSFVAGTGLTAVASAGFYAYLLTHVLFLNYVWGYTLLEA
Rv3728|M.tuberculosis_H37Rv         APMVEPTLLRIQSFVAGTGLTAVASAGFYAYLLTHVLFLNYVWGYTLLEA
MMAR_1306|M.marinum_M               VPLVEPAYLRSRPFVVGNVLTLVAAAGFYCYVLTHVLYLNYVWGYSLLKA
MUL_3590|M.ulcerans_Agy99           TPLIDPAFLRVRSFVAGNLLTLVAAAGFYCYVLTHVLYLNYVWHYSLLKA
MLBr_01562|M.leprae_Br4923          NPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRA
MAV_0138|M.avium_104                ------------------LGFVTIPG-------------RLHTALAAPVA
                                                             .                        

MSMEG_5167|M.smegmatis_MC2_155      AGAVACSIFAASAVTQVLANRVQP---GRAVAVGCAILIAGMLILTAALL
TH_0476|M.thermoresistible__bu      AGAVAASIFAASAVTQVLGASVSP---RRAVAVGCALLIVGMVFLAAALV
MAB_1299c|M.abscessus_ATCC_199      AGASVFLTFGSSCVAQILTRRVAA---AKALLIGCTILLTGMLLVVLALH
Mflv_1450|M.gilvum_PYR-GCK          GGAVVATTAFAAALAQLAATRVPA---RYAAIIGDAGMAAALLLTIPVLL
Mvan_5329|M.vanbaalenii_PYR-1       GGAVVGTTAFAAALAQLAATRVPA---RYSAILGDAGMAAALLLTIPVLL
Mb3755|M.bovis_AF2122/97            GMAVAPAALVAAVVAAVLGRVADRHGYRFIVGIGALIWAASLLWYLKVVG
Rv3728|M.tuberculosis_H37Rv         GMAVAPAALVAAVVAAVLGRVADRHGYRFIVGIGALIWAASLLWYLKVVG
MMAR_1306|M.marinum_M               GFAIAPAALVAAVVAALLGRVADRHGHRLIVTLGALVWAGSLFWYLQRVG
MUL_3590|M.ulcerans_Agy99           GFAIAPAALIAAVVAAVLGRIADQRGHRLVVMAGAIIWAGSLVWYLQRVG
MLBr_01562|M.leprae_Br4923          GIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMN
MAV_0138|M.avium_104                AGTATLIVNGVSGAVQVLARALRWG--PQAGTAGAVLAALGYAVAAAAPS
                                    .          .    :                *      .         

MSMEG_5167|M.smegmatis_MC2_155      FSS------LPALIAAAVVSGVGQGMSFSRGLAAIAEKTPPDRRAEVSST
TH_0476|M.thermoresistible__bu      WSS------LPALIATAVVAGAGQGLSFSRGLAAVSARTPSDQRGEVSST
MAB_1299c|M.abscessus_ATCC_199      TSS------LPWYLASAVVVGIGQGISFSRGLAAIADRTPEDNRAEVTSS
Mflv_1450|M.gilvum_PYR-GCK          THQ------WQLVFVAAALLGATFGLGFGGSLRHLSNVVPPARRGETMSA
Mvan_5329|M.vanbaalenii_PYR-1       THQ------WQLVFVAAALLGATFGLGFGGSLRHLSDVVPAGRRGETMSA
Mb3755|M.bovis_AF2122/97            SQPDFLGEWLPGQILQGIGVGATFPLLGSAALARLAKGGSYATASAVTGT
Rv3728|M.tuberculosis_H37Rv         SQPDFLGEWLPGQILQGIGVGATFPLLGSAALARLAKGGSYATASAVTGT
MMAR_1306|M.marinum_M               TEPDFLRRWLPGQLLQGIGVGATLPVLSSAALTGVAKGGSYATTSAVVST
MUL_3590|M.ulcerans_Agy99           TEPNFLREWLPGQLLQGIGVGATLPVLGSAALAGLTKGGSYATASAVVST
MLBr_01562|M.leprae_Br4923          RGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVG-FDRIGPVSAIALM
MAV_0138|M.avium_104                TLTP------ALGVPLFVVLGCASGLCLREGLIDLEAAAPQRLRGGLTGL
                                                 .      *         .:  :         .     

MSMEG_5167|M.smegmatis_MC2_155      YFVV-AYVAISLPVVGEGLSAQHWGLRPAGIAFALAVCVLAVICLVAILV
TH_0476|M.thermoresistible__bu      YFVV-AYVALLVPVIGEGWAAHHWGLRTAGISFAVGVAVLAIGCLIAILI
MAB_1299c|M.abscessus_ATCC_199      YFVV-AYIGIALPVIGEGLAAQAWGLRTAGVTFALAVAALAALCLIAVIW
Mflv_1450|M.gilvum_PYR-GCK          FYLL-AYSAMAVPTLVAGWAATRWELASVFPWFAGIVSAACLGAAVAGLR
Mvan_5329|M.vanbaalenii_PYR-1       FYLL-AYSAMAVPTLIAGWAATRWDLAAVFPWFAGVVAAACMGAAIAGVR
Mb3755|M.bovis_AF2122/97            IRQVGAVIGVAVLVILVGTPAPGAAEEALRHRWALAAICFVAVGIGALSL
Rv3728|M.tuberculosis_H37Rv         IRQVGAVIGVAVLVILVGTPAPGAAEEALRHGWALAAICFVAVGIGALSL
MMAR_1306|M.marinum_M               TRQLGAVIGVAALVILIGKPEHGAAADALRRGWAMAAICFVVVAIAAVLL
MUL_3590|M.ulcerans_Agy99           TRQLGAVIGVALLVILIGKPAPGTGVEALRHGWVLAAVCFAAVAVLAGFL
MLBr_01562|M.leprae_Br4923          LQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYTYGL
MAV_0138|M.avium_104                FYVV-TYIGFGLPLILASVRPG--VATAILSGMAVLAVTAAVGRAARLRR
                                       :     .                 .        .             

MSMEG_5167|M.smegmatis_MC2_155      EESRQRRAESAELSAST---------------------------------
TH_0476|M.thermoresistible__bu      QESRDPQAI-----------------------------------------
MAB_1299c|M.abscessus_ATCC_199      QERPSRTEALAPVSTG----------------------------------
Mflv_1450|M.gilvum_PYR-GCK          SIRVARAA------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       SVRLAQ--------------------------------------------
Mb3755|M.bovis_AF2122/97            GRIRPVPAAVEPPPGPPVAPLGARRPPRPAPVASPAAAVAPTPKTSREVN
Rv3728|M.tuberculosis_H37Rv         GRIRPVPAAVEPPPGPPVAPLGARRPPRPAPVASPAAAVAPTPKTSREVN
MMAR_1306|M.marinum_M               GRTNSK-PGQELEPEP---AAAARAAP---TTTEPAAALIAN-RATDEAD
MUL_3590|M.ulcerans_Agy99           GRTQQG-ADVAGAPESGVARAPARPQP---VTPRPAAAPARPPQTTADGD
MLBr_01562|M.leprae_Br4923          LWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL-----------
MAV_0138|M.avium_104                DDHRQN--------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            LLEALRFAR-----------PDTQQIELQAGSYLFHAGDVSDALYVVRSG
Rv3728|M.tuberculosis_H37Rv         LLEALRFAR-----------PDTQQIELQAGSYLFHAGDVSDALYVVRSG
MMAR_1306|M.marinum_M               LLGNLPLFAGLDAAALAELADRVEEVELQAGSYLFLAGDASDSLYVIRRG
MUL_3590|M.ulcerans_Agy99           LLRQLPLFAGLPAATMAELRHHTDEIELQAGSYLFHEVDPSDALYVVRSG
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            RLQVLAGDGAKDEVVAELGRGQVVGELGVLLDAPRSASVRAVRDSSLMRV
Rv3728|M.tuberculosis_H37Rv         RLQVLAGDGAKDEVVAELGRGQVVGELGVLLDAPRSASVRAVRDSSLMRV
MMAR_1306|M.marinum_M               RVQVLHGD----IVIKELGRGEVLGELGLLIDAPRSASVRALRDSRLVRL
MUL_3590|M.ulcerans_Agy99           RLRVVQRD----LVLRELGRGEVVGELGLLIDAPRSASVQAMRDFVLIRL
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            TKAEFAKIADAGVLGALAGVLAKRQHQTR--VASQRTTPEVVVAVVGVDA
Rv3728|M.tuberculosis_H37Rv         TKAEFAKIADAGVLGALAGVLAKRQHQTR--VASQRTTPEVVVAVVGVDA
MMAR_1306|M.marinum_M               TKAQFDQIANRGVLAALVRVLATRLREAPPPAVHT-TSPGVVVSVVGVGA
MUL_3590|M.ulcerans_Agy99           SKAQFNRIADRGVLAALVGTLATRLHTAPPPTVDRPASPEAVIAVIGLGA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            NAPVAMVATELCRALSTRLRAVAPGRVDCDGLERAEQTADRVVLHAAVGD
Rv3728|M.tuberculosis_H37Rv         NAPVAMVATELCRALSTRLRAVAPGRVDCDGLERAEQTADRVVLHAAVGD
MMAR_1306|M.marinum_M               DAPVQSVAAGLLTALSKQLRVVDPGRVDIDGLDRAERGADKVLLHAGAQD
MUL_3590|M.ulcerans_Agy99           AVPVRPVALALLNALSARVTAVDPGRVDRAGLERAEASADKVVLDASAND
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            ARWREFCLRVADRVVLVASNPAVPVAPLPTRATGADLVLAGRPAGREHRR
Rv3728|M.tuberculosis_H37Rv         ARWREFCLRVADRVVLVASNPAVPVAPLPTRATGADLVLAGRPAGREHRR
MMAR_1306|M.marinum_M               ADWRDFCLRVADRIVLVTGDPDPGAAALPARAQGADLVLAGPTASREQRR
MUL_3590|M.ulcerans_Agy99           TGWRDFCLRAADRIVLVSEGPAPRDTQLPARAVGADLVLIGAPASQEDRS
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            AWEQLITPRSMHVVRREFVADDLRVLATRIAGRSVGLVLSGGAARACAHL
Rv3728|M.tuberculosis_H37Rv         AWEQLITPRSMHVVRREFVADDLRVLATRIAGRSVGLVLSGGAARACAHL
MMAR_1306|M.marinum_M               SWEELITPRSVHAVHYRRVVQDLRPLAARLAGRSIGLVLGGGGARGFAHL
MUL_3590|M.ulcerans_Agy99           RWEELIPPRSVHSVSYRSLKDDVRPLAARITGGSIGLVLGGGGARAFAHL
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            GVLEELEAAGVTVDRFAGTSMGAIIAALAASGLDAAGVDAQIYEHFVRKS
Rv3728|M.tuberculosis_H37Rv         GVLEELEAAGVTVDRFAGTSMGAIIAALAASGLDAAGVDAQIYEHFVRKS
MMAR_1306|M.marinum_M               GILEELEQAGVAIDRFAGTSMGAVIASLGASGLDAATADAYAYEYFIRNN
MUL_3590|M.ulcerans_Agy99           GVLDELEAAGIVVDRFAGTSMGAVIAALAASGLDAAGVDAHVFEYLVRHN
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            -HGDYTLPSKGLIRGKRTQSTLRTIFGDHLVEELPKHFRCVSVDLLARRP
Rv3728|M.tuberculosis_H37Rv         -HGDYTLPSKGLIRGKRTQSTLRTIFGDHLVEELPKHFRCVSVDLLARRP
MMAR_1306|M.marinum_M               PLRDYAVPIKGLVRGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLIARQP
MUL_3590|M.ulcerans_Agy99           PLGDYTLPSKGLVRGRRTMGLLREAYSGRMVEELPKEFRCVSVDLLARQA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            VVHRQGPLADVVGCSMRLPFLYAPLPYGGTLHVDGGVLDNVPVTTLVGKD
Rv3728|M.tuberculosis_H37Rv         VVHRQGPLADVVGCSMRLPFLYAPLPYGGTLHVDGGVLDNVPVTTLVGKD
MMAR_1306|M.marinum_M               VVHRRGRLVDVVGCSLRLPGIYPPQVYQGRLHVDGGVLDNLPVSTLATSD
MUL_3590|M.ulcerans_Agy99           VVHRRGPVAEVVGCSLRVPGLYPPQIYNGQLHVDGGVLNNLPVTALTRAE
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            GPLIAVNVASGGNPSPASGGHRRGKPRVPGLTDTLLRTMTISSAMASEKV
Rv3728|M.tuberculosis_H37Rv         GPLIAVNVASGGNPSPASGGHRRGKPRVPGLTDTLLRTMTISSAMASEKV
MMAR_1306|M.marinum_M               GPLIAVSLASGEVP--GAPLQPDGPPRVPGIGDTLIRTMTIGSQRGADVA
MUL_3590|M.ulcerans_Agy99           GPMIAVSVGFGGNPS-GGQPRRSGPIQVPGIGDTLMRTMMMGSRTVADAA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      --------------------------------------------------
TH_0476|M.thermoresistible__bu      --------------------------------------------------
MAB_1299c|M.abscessus_ATCC_199      --------------------------------------------------
Mflv_1450|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5329|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3755|M.bovis_AF2122/97            LAQADLVIKPNPIGVGLMEYHQIDRAREAGRIAAREALPQIMELVHG---
Rv3728|M.tuberculosis_H37Rv         LAQADLVIKPNPIGVGLMEYHQIDRAREAGRIAAREALPQIMELVHG---
MMAR_1306|M.marinum_M               LGLAQVVIRPDTSAVGLLEFHQIDAAREAGRAAARESMPQIMALLNQ---
MUL_3590|M.ulcerans_Agy99           QAEALVVIRPDTRAVGLLEFHQIDAAREAGRAAARAALPQIIPLLRSGPA
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
MAV_0138|M.avium_104                --------------------------------------------------
                                                                                      

MSMEG_5167|M.smegmatis_MC2_155      -----------------------
TH_0476|M.thermoresistible__bu      -----------------------
MAB_1299c|M.abscessus_ATCC_199      -----------------------
Mflv_1450|M.gilvum_PYR-GCK          -----------------------
Mvan_5329|M.vanbaalenii_PYR-1       -----------------------
Mb3755|M.bovis_AF2122/97            -----------------------
Rv3728|M.tuberculosis_H37Rv         -----------------------
MMAR_1306|M.marinum_M               -------------------RR--
MUL_3590|M.ulcerans_Agy99           GQTTGRAIDRSARALRTDARRPA
MLBr_01562|M.leprae_Br4923          -----------------------
MAV_0138|M.avium_104                -----------------------