For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3412 | - | - | 100% (502) | putative major facilitator superfamily MFS_1 |
| M. thermoresistible (build 8) | TH_2682 | - | 2e-44 | 27.51% (498) | PUTATIVE transmembrane efflux protein |
| M. thermoresistible (build 8) | TH_3965 | - | 7e-40 | 29.37% (463) | PUTATIVE drug transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2361c | - | 8e-52 | 29.86% (489) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0241 | - | 8e-99 | 39.56% (503) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2333c | - | 1e-51 | 29.86% (489) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01562 | - | 1e-34 | 29.20% (435) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_2958 | - | 3e-90 | 39.63% (492) | putative transmembrane-transport protein |
| M. marinum M | MMAR_1146 | - | 6e-74 | 34.44% (482) | integral membrane transport protein |
| M. avium 104 | MAV_1387 | - | 4e-37 | 28.71% (418) | drug transporter |
| M. smegmatis MC2 155 | MSMEG_6225 | - | 1e-103 | 41.73% (496) | proton antiporter efflux pump |
| M. ulcerans Agy99 | MUL_0911 | - | 2e-73 | 33.82% (482) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_0664 | - | 2e-97 | 40.16% (493) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0241|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0664|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6225|M.smegmatis_MC2_155 -------------------------------MSTCIEGTPS------TTR
MAB_2958|M.abscessus_ATCC_1997 -------------------------------MTSCKSTAPENATAPEGAR
TH_3412|M.thermoresistible__bu -------------------------------MTQC------------AVR
MMAR_1146|M.marinum_M --------------------------------------------MRIQPV
MUL_0911|M.ulcerans_Agy99 --------------------------------------------MRIQPV
Mb2361c|M.bovis_AF2122/97 --------------------------------------------------
Rv2333c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1387|M.avium_104 --------------------------------------------------
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mflv_0241|M.gilvum_PYR-GCK -MSRRWLALGVLTLAVLLIGVDGTVLALATPFISADLGATGTELLWIGDI
Mvan_0664|M.vanbaalenii_PYR-1 -MTRRWSALAVLTLAVLLIGIDGTVLALATPFISADLGATGTQILWIGDI
MSMEG_6225|M.smegmatis_MC2_155 TPTRAWVALAVLALPVLLIAIDNTVLAFALPLIAEDFRPSATTQLWIVDV
MAB_2958|M.abscessus_ATCC_1997 VGRRTWFGLASLLLPVFLVSMDVSVLFLAMPRLSESLNPSAAEQLWILDV
TH_3412|M.thermoresistible__bu AGAREWAGLGVLAVPTVLLGLDVTVLYLVLPAVAADLAPSPVQTLWIMDA
MMAR_1146|M.marinum_M FRDHPIPALAVICLSVFVISVDATIVNVALPTLSRQLGADTAQLQWIVDA
MUL_0911|M.ulcerans_Agy99 FRDHPILALAVICLSVFVISVDATIVNVALPTLSRELGADTAQLQWIVDA
Mb2361c|M.bovis_AF2122/97 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVAS
Rv2333c|M.tuberculosis_H37Rv MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVAS
MAV_1387|M.avium_104 -----------MMIGFFMIMVDSTIVAIANPTIMADLHIGYDTVVWVTSA
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
.: :* : .. * : .: *
Mflv_0241|M.gilvum_PYR-GCK YSFVLAALLVTMGSLGDRVGHRKLLLCGATAFSAVSALTAYSTSPEMLIG
Mvan_0664|M.vanbaalenii_PYR-1 YSFVLAALLISMGSLGDRIGHRKLLLCGATAFAVISAVTAYSTSPQMLIL
MSMEG_6225|M.smegmatis_MC2_155 YSLVLAALLVAMGSLGDRLGRRRLLLIGGAGFAVVSALAAFAPSAELLVG
MAB_2958|M.abscessus_ATCC_1997 YGFLLAGLLITMGNLGDRWGRRRLMLWGATLFAAASVLAAFAPTPLALIG
TH_3412|M.thermoresistible__bu YGFFIAGFLITMGTLGDRIGRRRLLTIGVTAFAGASVLAALAPSAELLIV
MMAR_1146|M.marinum_M YTLVMSGLLLSAGSLSDRYGRRGWLSAGLILFALTSALAAQVNSADTLIA
MUL_0911|M.ulcerans_Agy99 YTLVMSGLLLSAGSLSDRYGRRGWLSAGLILFALTSALAAQVNSADTLVA
Mb2361c|M.bovis_AF2122/97 YSLGMAVFIMSAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTT
Rv2333c|M.tuberculosis_H37Rv YSLGMAVFIMSAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTT
MAV_1387|M.avium_104 YLLGYAVVLLVAGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLIA
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
* : . .:: . *.* * : * *: * . *
Mflv_0241|M.gilvum_PYR-GCK TRALLGMAGATLAPATLALIRGLFPDSRERSIAVGIWASAFSAGAALGPV
Mvan_0664|M.vanbaalenii_PYR-1 TRALLGMAGATLTPATLALIRGLFPDQRERSIAVGIWASAFSAGAALGPV
MSMEG_6225|M.smegmatis_MC2_155 ARALLGVFGAMLMPSTLSLIRNIFTDASARRLAIAIWASCFTAGSALGPI
MAB_2958|M.abscessus_ATCC_1997 ARALMGVGGATLLPASLALIGVMFPNPRQKALAIGIWSAAFSFGAAVGPV
TH_3412|M.thermoresistible__bu ARALLGVAGATLMPSTLSLISNMFVDAAQRALAIGVWATMFAVGMAAGPV
MMAR_1146|M.marinum_M ARAAMGVGAAVIFPTTLGLITNIFTDPVPRAKAIGLWTAMVGVGVAVGPI
MUL_0911|M.ulcerans_Agy99 ARAAMGVGAAVIFPTTLGLITNIFTDPVPRAKAIGLWTAMVGVGVAVGPI
Mb2361c|M.bovis_AF2122/97 ARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIGIWTAIASIGTTTGPT
Rv2333c|M.tuberculosis_H37Rv ARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIGIWTAIASIGTTTGPT
MAV_1387|M.avium_104 ARVVQGVGAGVMTPQTLSTITRIFP-AERRGVAVSVWSATAGAASLAGPL
MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
:* *: .. *. : * : * .:::: . *
Mflv_0241|M.gilvum_PYR-GCK VGGVLLEHFWWGSVFLINIPVMVILLVGGLVLLPEHRDPDPGPWDLPSVA
Mvan_0664|M.vanbaalenii_PYR-1 VGGVLLEHFWWGSVFLINIPVMVILLVGGVLLLPEHRNPDPGPWDLPSVA
MSMEG_6225|M.smegmatis_MC2_155 VGGALLEHFHWGAVFLVAVPILLPLLVLGPRLVPESRDPNPGPFDPVSIV
MAB_2958|M.abscessus_ATCC_1997 IGGVLLHHFWWGSVFLINVPVLIVLLLTADALIPEYRNPIRAPFDLVGVA
TH_3412|M.thermoresistible__bu VGGALVDRFWWGAAFLLAVPVAAAVLLG-ARLLPEYADPQAGRLDLRSVA
MMAR_1146|M.marinum_M TGGWLLEHFSWGSIFLVNVPIAVAAMAGAILFVPTSRDPAAPRVDVPGLM
MUL_0911|M.ulcerans_Agy99 TGGWLLEHFSWGSIFLVNVPIAVAAMAGAILFVPTSRDPAAPRVDVPGLM
Mb2361c|M.bovis_AF2122/97 LGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFDLSGQL
Rv2333c|M.tuberculosis_H37Rv LGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFDLSGQL
MAV_1387|M.avium_104 AGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVP-VLPTQSHRFDLVGVG
MLBr_01562|M.leprae_Br4923 VGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETHKER-MKLDAAGAI
** * . * * : :*: : : * .
Mflv_0241|M.gilvum_PYR-GCK LSMVGMLGIVYAIKEGFTGLVHGLGAEVVIAAAVGVAALTLFVRRQLRLP
Mvan_0664|M.vanbaalenii_PYR-1 LSMVGMLAVVYAVKEGFAGLAHGVGPDVAVAGLVGAAALTMFVRRQLRLP
MSMEG_6225|M.smegmatis_MC2_155 LSFTTMLPIVWAVKT---AAHDGLSAAAAAAFAVGIVSGALFVRRQNRSA
MAB_2958|M.abscessus_ATCC_1997 LSMVGIMTLVYSVKA---MATHGFSAAVAITGAVGVLTLALFVRQQVRNP
TH_3412|M.thermoresistible__bu LSLLAILAAIYAVKH---VAVHGVDGVAVAACALAAAAATVFVHRQRRLD
MMAR_1146|M.marinum_M LSAVGITALVYTIIEAP--NWGWTSTRASGGFIAAAIVLVGFALWERRSS
MUL_0911|M.ulcerans_Agy99 LSAVGITALVYTIIEAP--NWGWTSTRASGGFIAAAIVLVGFALWERRSS
Mb2361c|M.bovis_AF2122/97 LFIVAVGALVYAVIEGP--QIGWTSVQTIVMLWTAAVGCALFVWLERRSS
Rv2333c|M.tuberculosis_H37Rv LFIVAVGALVYAVIEGP--QIGWTSVQTIVMLWTAAVGCALFVWLERRSS
MAV_1387|M.avium_104 LSGVGMLLIVFGLQQGQ--AAHWQPWIWALIVAGVGFVTVFVFWQSVNVR
MLBr_01562|M.leprae_Br4923 LATLACTAAVFAFSMGP--EKGWISLTTIGSGLVALVAAIAFAVVERTAE
* :: . . .
Mflv_0241|M.gilvum_PYR-GCK HPLIDVRLFANPRFSGVVGANLFSVLGLSGLVFFLSQYFQLVHGYGPLKA
Mvan_0664|M.vanbaalenii_PYR-1 APLIDVRLFANPRFSGVVAANLLSVLGLSGLVFFLSQYFQLVHGYGPLKA
MSMEG_6225|M.smegmatis_MC2_155 TPMLDIGLFKVMPFTSSILANFLSIIGLIGFIFFISQHLQLVLGLSPLTA
MAB_2958|M.abscessus_ATCC_1997 HPLLALDLFRNRTFTVAIVGTVGAMATFGATTYLTGLYVQSVLGFDVLAA
TH_3412|M.thermoresistible__bu APLLDVTLFADRAFTAALTVLLIGLIGVGGTMYLVTQFLQLVEGLTPVRA
MMAR_1146|M.marinum_M HPMLDVSVFANRRFSGGSLAVTAGFLTLFGFIFVITQYFQFIKDYTALQT
MUL_0911|M.ulcerans_Agy99 HPMLDVSVFANRRFSGGSLAVTAGFLTLFGFIFVITQYFQFIKDYTALQT
Mb2361c|M.bovis_AF2122/97 NPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVT
Rv2333c|M.tuberculosis_H37Rv NPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVT
MAV_1387|M.avium_104 EPLIPLVIFSDRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRS
MLBr_01562|M.leprae_Br4923 NPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRA
*:: . :* . . * : . :
Mflv_0241|M.gilvum_PYR-GCK GLAELPAAVTATVFGVLAGVAVRYFSHRSVLTTGLALVGTAMAALMASLL
Mvan_0664|M.vanbaalenii_PYR-1 GLAELPAAVTATVFGVLAGVAVRYVSHRAVLATGLALVGVAMAAMTTSLL
MSMEG_6225|M.smegmatis_MC2_155 GLVTLPGAVVSMIAGLAVVKAAKRFAPDTLMVTGLVFVAVG----FLMIL
MAB_2958|M.abscessus_ATCC_1997 AFLGLPMAVVVAYFSMDAPRIERVLGERWTFVTSLLAMALG----NAVLL
TH_3412|M.thermoresistible__bu GWWMGPPALAMFVAAIGAPLIARRVRPGVVMAATLGVSVLG-----YAVL
MMAR_1146|M.marinum_M GVRLLPVALSIALAAILGPRLVERVGTTAVVAAGLAVFAAA----LAWAS
MUL_0911|M.ulcerans_Agy99 GVRLLPVAFSIALAAILGPRLVERVGTTAVVAAGLAVFAAA----LAWAS
Mb2361c|M.bovis_AF2122/97 GLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLG-----LLML
Rv2333c|M.tuberculosis_H37Rv GLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLG-----LLML
MAV_1387|M.avium_104 ALLIAPMAIANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALT---WLTF
MLBr_01562|M.leprae_Br4923 GIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLY--GWAF
. * .
Mflv_0241|M.gilvum_PYR-GCK IFRPLTPYLPLGISLFVVGVGLGLAFTVASDVILASVPKERAGAAAAVSE
Mvan_0664|M.vanbaalenii_PYR-1 VFTPVAPYLPLGVALFVVGVGLGLAFTVASDVILASVPRERAGAAAAVSE
MSMEG_6225|M.smegmatis_MC2_155 LFRHNLTVAAIIASFVVLELGVGVSQTVSNDTIVASVPAAKSGAASAVSE
MAB_2958|M.abscessus_ATCC_1997 ALGPHGPVAVYIAATVIVGAGAGVMFTFVSAVALGAAPTERAGQATGISE
TH_3412|M.thermoresistible__bu ASAGRGDGPAVVVAFAFVYLGLGAIAALGTDIVVGAAPAAKSGSAAAMSE
MMAR_1146|M.marinum_M TADATTPYTQIALQMLLLGGGLGLTTAPATEAIMGSLPADRAGVGSAVND
MUL_0911|M.ulcerans_Agy99 TADATTPYTQITLQMLLLGGGLGLTTAPATEAIMGSLPADRAGVGSAVND
Mb2361c|M.bovis_AF2122/97 IFSEHRSSALVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMS
Rv2333c|M.tuberculosis_H37Rv IFSEHRSSALVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMS
MAV_1387|M.avium_104 EMSPATPIWRLVLPFFAMGVGMAFVWSPLTATATRNLSAQLAGAGSAVYN
MLBr_01562|M.leprae_Br4923 MNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIAL
* . . * :.:
Mflv_0241|M.gilvum_PYR-GCK TAYELGMALGIAVLGSILTAVYRT-V---TIPAGVPAD------------
Mvan_0664|M.vanbaalenii_PYR-1 TAYELGMALGIAMLGSIVTAVYRT-V---VIAPEIPSA------------
MSMEG_6225|M.smegmatis_MC2_155 TAYELGAVVGTATLGTIFTAFYRSNV---DVPAGLTPE------------
MAB_2958|M.abscessus_ATCC_1997 MSFELGTAFGLALFGALASAVFAA--------------------------
TH_3412|M.thermoresistible__bu TVQELGIAVGVALLGSVTAAVYRSRM---TGPEGVAEG------------
MMAR_1146|M.marinum_M TTRELGGTLGVAIAGSVFASVYSGQLGSASTLATLPSD------------
MUL_0911|M.ulcerans_Agy99 TTRELGGTLGVAIAGSVFASVYSGQLGSASALATLPSD------------
Mb2361c|M.bovis_AF2122/97 AQRAIGSTIGFAVLGSVLAAWLSATLEPHLERAVPDPV------------
Rv2333c|M.tuberculosis_H37Rv AQRAIGSTIGFAVLGSVLAAWLSATLEPHLERAVPDPV------------
MAV_1387|M.avium_104 SVRQLGAVLGSAGMAAFMTWRIGAEMPGQPGGGGEDSAGPVLPEFLRGPF
MLBr_01562|M.leprae_Br4923 MLQSLGGPLVLAVIQAVITSRTLYLG------------------------
:* . * :. :
Mflv_0241|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0664|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6225|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2958|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3412|M.thermoresistible__bu --------------------------------------------------
MMAR_1146|M.marinum_M --------------------------------------------------
MUL_0911|M.ulcerans_Agy99 --------------------------------------------------
Mb2361c|M.bovis_AF2122/97 --------------------------------------------------
Rv2333c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1387|M.avium_104 AAAMSQSVLLPAFIALFGIVAALFLVGFRPWAHRDGGTDAFGPDDYGGDY
MLBr_01562|M.leprae_Br4923 --------------------------------------------------
Mflv_0241|M.gilvum_PYR-GCK ---------------AAAQARDSLPKAIDAARGLPDAAQS------ALLE
Mvan_0664|M.vanbaalenii_PYR-1 ---------------AADLARDSLPGAIHAAHSLPADQQS------TLLD
MSMEG_6225|M.smegmatis_MC2_155 ---------------QTGAAAESIGGAAAVAADLPAATAT------QLLD
MAB_2958|M.abscessus_ATCC_1997 ----------------RTHVHETLGQAMANAKELGGDAGA------AAAE
TH_3412|M.thermoresistible__bu ---------------VGGPDAERLAESLPAAVSVADRVPG------EAVR
MMAR_1146|M.marinum_M ---------------VRSAMKGSMAVAHKVIDQLPAGPAA------GVRD
MUL_0911|M.ulcerans_Agy99 ---------------VRSAMKGSMAVAHKVIDQLPAGPAA------GVRD
Mb2361c|M.bovis_AF2122/97 ---------------QRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVA
Rv2333c|M.tuberculosis_H37Rv ---------------QRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVA
MAV_1387|M.avium_104 HDDYDDDDAYVELILVREPEPEAQQRAGQPRRPQPTPAPPADVRRRDPVE
MLBr_01562|M.leprae_Br4923 ----------------GTTGPVKFMNDAQLRALDHGYTYG-------LLW
Mflv_0241|M.gilvum_PYR-GCK SAKESFTLG---LSVSAGVGAALLLTSAVAVWWLLR--SPGPAEVGVLPD
Mvan_0664|M.vanbaalenii_PYR-1 AARASFTHG---LASASAAGAVLLLTAAVAVWWLLRPGSPGAAEVGVLAD
MSMEG_6225|M.smegmatis_MC2_155 SARAAFDSG---IAPTAVIAAMLVLAAAAVVGVAFRR-------------
MAB_2958|M.abscessus_ATCC_1997 LARTGWADG---IHAVASVSTLLLVAIAVAAAVVMRRTQD----------
TH_3412|M.thermoresistible__bu LAQDAFAAG---VNIAALIGGAAVVVVAVVCATALRHLRPLD--------
MMAR_1146|M.marinum_M AVNHAFLDG---LQVATLVCAGIALAAAIVVGWLLPARAGQPTPAQTEPA
MUL_0911|M.ulcerans_Agy99 AVNHAFLDG---LQVATLVCAGIALAAAIVVGWLLPARAGQPTPAQTEPA
Mb2361c|M.bovis_AF2122/97 IAEEDFIEG---IRVALLVATATLAVVFLAGWRWFPRDVQTAGSDAKR--
Rv2333c|M.tuberculosis_H37Rv IAEEDFIEG---IRVALLVATATLAVVFLAGWRWFPRDVHTAGSDLSERL
MAV_1387|M.avium_104 SRRSVLDERPAQVQPIGFAHNGSHVDGGKRLRQVAVRRAPKPGPPADRFT
MLBr_01562|M.leprae_Br4923 VAGAVVIVG---VAALFIGYTPEQVAYAQEVKEAVDAGEL----------
:
Mflv_0241|M.gilvum_PYR-GCK PGVHHDARGDGGVDTAGGAELGNRHS------------------
Mvan_0664|M.vanbaalenii_PYR-1 PGVHRDPGRDARVDAPGGAELGDRNS------------------
MSMEG_6225|M.smegmatis_MC2_155 --------------------------------------------
MAB_2958|M.abscessus_ATCC_1997 --------------------------------------------
TH_3412|M.thermoresistible__bu --------------------------------------------
MMAR_1146|M.marinum_M LAQA----------------------------------------
MUL_0911|M.ulcerans_Agy99 LAQV----------------------------------------
Mb2361c|M.bovis_AF2122/97 EAAYSDDRRVRG--------------------------------
Rv2333c|M.tuberculosis_H37Rv PTAMTVECAVSHMPGATWCRLWPA--------------------
MAV_1387|M.avium_104 RPPRRHHPGPAGHHLGEGESLRGQHHRPDPDDDPTGYGRHSSGN
MLBr_01562|M.leprae_Br4923 --------------------------------------------