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GFLAQFRSFNRPSRVLMINQFGINVGFYMLMPYLADYLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTL ADRFGYKPLIVAGCLIRTGGFALLVVAQSLPSVLIASAATGFAGALFNPAVRAYVAADSGDRKLEAFAMF NIFYQAGILLGPLVGLALLTLDFRMTVLGASAVFAVLTAAQLMALPQHLADPGTKNESILQGWKAIVRNR SFLGFAAAMTGAYVLSFQVYLALPMQASLLAPGHQSVLVAAMFAVSGLIAIAGQLRITRWFAAHWRVSRS LVVGAAILAIAFVPLAMVPNAQRFGTGAAVAALLVSASLLAVASAALFPFEMRTVVVLAEDKLVATHYGF YSTIVGVGILVGNLVVGSLMSVAHRFGADEIVWGGLILIGLATVAGLYQLDRQATRADRLSRRHPPAQLC QQAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4767 | - | - | 100% (425) | integral membrane transport protein |
| M. marinum M | MMAR_0136 | - | 2e-07 | 28.78% (205) | intergral membrane protein |
| M. marinum M | MMAR_1887 | efpA | 1e-05 | 28.44% (109) | integral membrane efflux protein EfpA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0872 | - | 1e-180 | 75.60% (414) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0900 | - | 1e-151 | 65.10% (404) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0849 | - | 1e-180 | 75.60% (414) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01562 | - | 3e-06 | 29.36% (109) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_1274 | - | 1e-142 | 61.43% (420) | ABC transporter permease |
| M. avium 104 | MAV_3702 | - | 1e-05 | 29.36% (109) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_5464 | - | 1e-08 | 23.60% (322) | integral membrane transport protein |
| M. thermoresistible (build 8) | TH_3412 | - | 5e-10 | 23.88% (402) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0338 | - | 0.0 | 97.41% (425) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_5855 | - | 1e-152 | 66.83% (404) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4767|M.marinum_M ------------------------------------------MGFLAQFR
MUL_0338|M.ulcerans_Agy99 ------------------------------------------MGFLAQFR
Mb0872|M.bovis_AF2122/97 ------------------------------------------MGARAIFR
Rv0849|M.tuberculosis_H37Rv ------------------------------------------MGARAIFR
Mflv_0900|M.gilvum_PYR-GCK ------------------------------------------MTLLSGFG
Mvan_5855|M.vanbaalenii_PYR-1 ------------------------------------------MNLVSGFR
MAB_1274|M.abscessus_ATCC_1997 --------------------------MDQAHPRDRPDREEGVIQTLRQFR
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVE----PASERTSKYPTLLP
MAV_3702|M.avium_104 MTALNDSERAVQNWTSARPDRPAPVRSTPPAETAPKPAAETAVKRTSKYY
TH_3412|M.thermoresistible__bu --------------------------------------MTQCAVRAGARE
MSMEG_5464|M.smegmatis_MC2_155 ----------------------------------------------MRTR
MMAR_4767|M.marinum_M SFNRPSRVLMINQFGIN-VGFYMLMPYLADYLAGP-----LGLAAWAVGL
MUL_0338|M.ulcerans_Agy99 SFNRPSRVLMINQFGIN-VGFYMLMPYLADYLAGP-----LGLAAWAVGL
Mb0872|M.bovis_AF2122/97 GFNRPSRVLMINQFGIN-IGFYMLMPYLADYLAGP-----LGLAAWAVGL
Rv0849|M.tuberculosis_H37Rv GFNRPSRVLMINQFGIN-IGFYMLMPYLADYLAGP-----LGLAAWAVGL
Mflv_0900|M.gilvum_PYR-GCK SFGWPSRMLMINQFGIN-LGFYMLMPYLAGYLAGP-----LGLAAWAIGL
Mvan_5855|M.vanbaalenii_PYR-1 SFGWPSRMLMINQFGIN-LGFYMLMPYLAGYLAGP-----LGLAAWAIGL
MAB_1274|M.abscessus_ATCC_1997 SFDRPSQILMVNQFAIN-VGFYMLMPYLAGYLAGP-----LGLAAWMVGL
MLBr_01562|M.leprae_Br4923 SGRFPSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSW
MAV_3702|M.avium_104 PAWLPSRRFIAAVIAIGGMQLLATMDSTVAIVALPRIQNELSLSDAGRSW
TH_3412|M.thermoresistible__bu WAGLGVLAVPTVLLGLDVTVLYLVLPAVAADLAPS---------PVQTLW
MSMEG_5464|M.smegmatis_MC2_155 SPAPLVGLCVFEFLSWG--ILYYTLPVIGVRITAAT-----GWPPLVVPV
: . : : :: .
MMAR_4767|M.marinum_M VMGVRNFSQQGMFFVGGTLADRFGYKPLIVAGCLIRTGGFALLVVAQSLP
MUL_0338|M.ulcerans_Agy99 VMGVRNFSQQGMFFVGGTLADRFGYKPLIVAGCLIRTGGFALLVVAQSLP
Mb0872|M.bovis_AF2122/97 VMGVRNFSQQGMFFVGGTLADRFGYKPLIIAGCLIRTGGFALLVVAQSLP
Rv0849|M.tuberculosis_H37Rv VMGVRNFSQQGMFFVGGTLADRFGYKPLIIAGCLIRTGGFALLVVAQSLP
Mflv_0900|M.gilvum_PYR-GCK VLGVRNFSQQGMFIIGGTLADRLGFKPLIVSGCVLRTAGFGLLVFADSLP
Mvan_5855|M.vanbaalenii_PYR-1 VLGVRNFSQQGMFIIGGTLADRLGYKPLIVAGCVLRTVGFGLLVLADSLP
MAB_1274|M.abscessus_ATCC_1997 VLGVRNFSQQGMFLVGGTLADRFGYKPLIVAGCFLRTAGFAMLAFVGTLP
MLBr_01562|M.leprae_Br4923 GITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEV
MAV_3702|M.avium_104 VITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEA
TH_3412|M.thermoresistible__bu IMDAYGFFIAGFLITMGTLGDRIGRRRLLTIGVTAFAGASVLAALAPSAE
MSMEG_5464|M.smegmatis_MC2_155 VYTTSLLCAAFATPWAGRMVDRHGPRPVMTLGSLVGAGALVLAGVTGWLP
. : * : * * : : * : . : ..
MMAR_4767|M.marinum_M SVLIASAATGFAGALFNPAVRAYVAADS--GDRKLEAFAMFNIFYQAGIL
MUL_0338|M.ulcerans_Agy99 SVLIAAAATGFAGALFNPAVRAYVAADS--GDRKLEAFATFNIFYQAGIL
Mb0872|M.bovis_AF2122/97 SVLIAAAATGFAGALFNPAVRGYLAAEA--GERKIEAFAMFNVFYQSGIL
Rv0849|M.tuberculosis_H37Rv SVLIAAAATGFAGALFNPAVRGYLAAEA--GERKIEAFAMFNVFYQSGIL
Mflv_0900|M.gilvum_PYR-GCK AVLVASAATGFAGALFNPAVRAYLAADA--GPRRLEAFALFNVFYQAGIL
Mvan_5855|M.vanbaalenii_PYR-1 AVLIASAATGFAGALFNPAVRAYLAVDA--GPRRLEAFALFNVFYQGGIL
MAB_1274|M.abscessus_ATCC_1997 AILIASAATGFAGALFNPAVRAYLAADS--GERRVEAFAVFNVFYQAGIL
MLBr_01562|M.leprae_Br4923 TLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSV
MAV_3702|M.avium_104 TMVIARLSQGVGSAIASPTGLALVATTFPKGPARNFATAVFAAMTAVGSV
TH_3412|M.thermoresistible__bu LLIVARALLGVAGATLMPSTLSLISNMFVDAAQRALAIGVWATMFAVGMA
MSMEG_5464|M.smegmatis_MC2_155 LFAVAWLVVGVAQAGTLYPPAFAAATQWFGTVRAWPLTAITLAGGVSSTA
. :* *.. * . : . .
MMAR_4767|M.marinum_M LGPLVGLALLTLDFR-MTVLGASAVFAVLTAAQLMALPQHLADPGT--KN
MUL_0338|M.ulcerans_Agy99 LGPLVGLALLTLDFR-MTVLGASAVFAVLTAAQLMALPQHLADPDT--KN
Mb0872|M.bovis_AF2122/97 LGPLVGLVLLALDFR-ITVLAAAGVFGLLTVAQLVALPQHRADSER--EK
Rv0849|M.tuberculosis_H37Rv LGPLVGLVLLALDFR-ITVLAAAGVFGLLTVAQLVALPQHRADSER--EK
Mflv_0900|M.gilvum_PYR-GCK AGPLVGLALMFVDFK-ITAAAAALVFAVLTVAQLFALPQRAVAPTP--EK
Mvan_5855|M.vanbaalenii_PYR-1 AGPLVGLALMFVDFR-ATAAAAAMVFAVLTVAQLFALPQRTAAPAE--AK
MAB_1274|M.abscessus_ATCC_1997 FGPIVGLALTAWDFR-ITCAVAAAVFAFLTVIQLMALPPNRAESERNADR
MLBr_01562|M.leprae_Br4923 MGLVVGGALTEVSWR-LAFLVNVPIGLVMIYLARTALHETHKERMKLDAA
MAV_3702|M.avium_104 MGLVVGGALTEVSWR-LAFLVNVPIGLVMMYLARTALRETNRERMKLDAT
TH_3412|M.thermoresistible__bu AGPVVGGALVDRFWWGAAFLLAVPVAAAVLLGARLLPEYADPQAGRLDLR
MSMEG_5464|M.smegmatis_MC2_155 FAPLTAALNEKLGWQTTLVVLGTGYGVVSTAAAALMLTSRWRRPVREGAE
. :.. :
MMAR_4767|M.marinum_M ESILQGWKAIVRNRSFLG------FAAAMTGAYVLSFQVYLALPMQASLL
MUL_0338|M.ulcerans_Agy99 ESILQGWKAIVCNRSFLG------FAAAMTGAYVLSFQVYLALPIQASLL
Mb0872|M.bovis_AF2122/97 TSILQDWRVVVRNRPFLT------LAAAMTGCYALSFQIYLALPMQASIL
Rv0849|M.tuberculosis_H37Rv TSILQDWRVVVRNRPFLT------LAAAMTGCYALSFQIYLALPMQASIL
Mflv_0900|M.gilvum_PYR-GCK TSVLQDWRAVAANRSFLL------FAAAMIGSYVLSFQVYLAMPLQARYL
Mvan_5855|M.vanbaalenii_PYR-1 TSVLDDWRVVAANRSFLL------FAAAMIGSYVLSFQVYLALPLQARDL
MAB_1274|M.abscessus_ATCC_1997 APVLTSWRSVVSNKAFLL------FSGAMIGSYVLTFQVYLALPLQAALL
MLBr_01562|M.leprae_Br4923 GAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTA
MAV_3702|M.avium_104 GAVLATLACTAAVFAFSMGPEKGWISLTTISSGVVALGAALAFVIVERTA
TH_3412|M.thermoresistible__bu SVALSLLAILAAIYAVKHVAVHG-VDGVAVAACALAAAAATVFVHRQRRL
MSMEG_5464|M.smegmatis_MC2_155 HAEYVTQIVRSAPFRRSR----LALAMTALGLYAVTLNVIPLLTELGFGY
. . . :: :
MMAR_4767|M.marinum_M AP--------------GHQSVLVAAMFAVSG-------------------
MUL_0338|M.ulcerans_Agy99 AP--------------GHQSVLLAAMFAVSG-------------------
Mb0872|M.bovis_AF2122/97 MP--------------RNQYLLIAAMFAVSG-------------------
Rv0849|M.tuberculosis_H37Rv MP--------------RNQYLLIAAMFAVSG-------------------
Mflv_0900|M.gilvum_PYR-GCK FP--------------QNDSVVTAMIFVVSG-------------------
Mvan_5855|M.vanbaalenii_PYR-1 FP--------------GSDSVVTAMIFVVSG-------------------
MAB_1274|M.abscessus_ATCC_1997 TDD--------K----KSETALVTSIFVVSG-------------------
MLBr_01562|M.leprae_Br4923 ENPVVPFDLFRD----RNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGY
MAV_3702|M.avium_104 ENPVVPFDLFRD----RNRLVTFIAIFLAGGVMFTLTVCIGLYVQDILGY
TH_3412|M.thermoresistible__bu DAPLLDVTLFADRAFTAALTVLLIGLIGVGG-------------------
MSMEG_5464|M.smegmatis_MC2_155 HS--------------AAIVFGLIGVGQVFG-------------------
: . *
MMAR_4767|M.marinum_M ------------LIAIAGQLRITRWFAAHWRVSRSLVVGAAILAIAFVP-
MUL_0338|M.ulcerans_Agy99 ------------LIAIAGQLRITRWVAAHWRVSRSLVVGAAILAMAFVP-
Mb0872|M.bovis_AF2122/97 ------------LVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIP-
Rv0849|M.tuberculosis_H37Rv ------------LVAVGGQLRITRWFAVRWGAERSLVVGATILAASFIP-
Mflv_0900|M.gilvum_PYR-GCK ------------VVAVLGQMRITRWFGRRWGSGRSLAIGMLILALSFLP-
Mvan_5855|M.vanbaalenii_PYR-1 ------------LVAVMGQMRITRWFAKRWGAGRSLMIGMLILAVSFVP-
MAB_1274|M.abscessus_ATCC_1997 ------------LVAIAGQVRLTGWLSARFGPSRSLVLGMLVIGTAFVP-
MLBr_01562|M.leprae_Br4923 SALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYG
MAV_3702|M.avium_104 SALRAGVGFIPFVIAMGIGLGVSSQLVARFSPRVLTIAGGYLLVLAMLYG
TH_3412|M.thermoresistible__bu --TMYLVTQFLQLVEGLTPVRAGWWMGPPALAMFVAAIGAPLIARRVRPG
MSMEG_5464|M.smegmatis_MC2_155 ------------RVLYLPLRRLGTPRARTTAQVAASTAGMGILAVVTAP-
: * ::
MMAR_4767|M.marinum_M ----LAMVPNAQRFGTGAAVAALLVSASLLAVASAALFPFEMRTVVVLAE
MUL_0338|M.ulcerans_Agy99 ----LAMVPNAQRFGTGAAVAALLVSASLLAVASAALFPFEMRTVVVLAE
Mb0872|M.bovis_AF2122/97 ----VAVIPNGQRFGVAVAVMALVLSASLLAVASAALFPFEMRAVVALSG
Rv0849|M.tuberculosis_H37Rv ----VAVIPNGQRFGVAVAVMALVLSASLLAVASAALFPFEMRAVVALSG
Mflv_0900|M.gilvum_PYR-GCK ----LIALPDDERAGRVAAATALLIATAVLAVGSAAVFPFEMDTVVSLAD
Mvan_5855|M.vanbaalenii_PYR-1 ----LMALPDDTRAGRVAAATALLGATAVLAVGSAAVFPFEMDTVVSLAG
MAB_1274|M.abscessus_ATCC_1997 ----LVLLPTAASAGQLAAIAALLFSAALLAVGTIATFPFEMDTVVRLAD
MLBr_01562|M.leprae_Br4923 WAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSA
MAV_3702|M.avium_104 WWCMHRGVPYFPNLVLPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSA
TH_3412|M.thermoresistible__bu ---VVMAATLGVSVLGYAVLASAGRGDGPAVVVAFAFVYLGLGAIAALGT
MSMEG_5464|M.smegmatis_MC2_155 ----------LALAASAAMFAGAARGTHTLSVANAVTDRWGAESYATILG
. . : . :
MMAR_4767|M.marinum_M DKLVATHYG--------FYSTIVGVGILVGNLVVG------SLMSVAHRF
MUL_0338|M.ulcerans_Agy99 DKLVATNYG--------FYSTIVGVGILVGNLAVG------SLMSVAHRF
Mb0872|M.bovis_AF2122/97 DRLVATHYG--------FYSTIVGVGVLVGNLAIG------SLMSAARRL
Rv0849|M.tuberculosis_H37Rv DRLVATHYG--------FYSTIVGVGVLVGNLAIG------SLMSAARRL
Mflv_0900|M.gilvum_PYR-GCK NRLVGTHYG--------FYNTIVGVGILVGNLATG------SLMQLAREL
Mvan_5855|M.vanbaalenii_PYR-1 NRLVGTHYG--------FYNTIVGVGILVGNLATG------YLMQAAKRV
MAB_1274|M.abscessus_ATCC_1997 NRLVATQYG--------LYNTIVGIGILAGNLLTG------SVFGYSQRR
MLBr_01562|M.leprae_Br4923 IALMLQSLGG------PLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLR
MAV_3702|M.avium_104 VTLMLQSLGG------PLVLAVIQAVITSRTLYLGGTTGPVKTMNDAQLQ
TH_3412|M.thermoresistible__bu DIVVGAAPAAKSGSAAAMSETVQELGIAVGVALLGSVTAAVYRSRMTGPE
MSMEG_5464|M.smegmatis_MC2_155 R-----------------FHRPVAIAMALGPATGS---------------
: .
MMAR_4767|M.marinum_M GADE---------IVWGG--LILIGLATVAGLYQLDRQA-TRADRLSRRH
MUL_0338|M.ulcerans_Agy99 GADE---------IVWGG--LILIGLATVAGLYQLDRQA-TRAERLSRRH
Mb0872|M.bovis_AF2122/97 NTDE---------IVWGG--LILVGIVAVAGLRRLDTFT-SGSQNMTGRW
Rv0849|M.tuberculosis_H37Rv NTDE---------IVWGG--LILVGIVAVAGLRRLDTFT-SGSQNMTGRW
Mflv_0900|M.gilvum_PYR-GCK GRPE---------FLWVL--LTVIGMLSAAALYRLDQRGRLGSTPKAVDD
Mvan_5855|M.vanbaalenii_PYR-1 GAPE---------LLWVL--LCAIGAVSALALYRLDRRGLLQPAKSTPDR
MAB_1274|M.abscessus_ATCC_1997 GVPS---------LLWVS--LVVVGLVCAAALFALRRAGLLDRGREVAPA
MLBr_01562|M.leprae_Br4923 ALDHGY----TYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDA
MAV_3702|M.avium_104 ALDHGY----TYGLLWVAGAAVIVGAAALFIGYTPEQVAHAQEVKEAMDA
TH_3412|M.thermoresistible__bu GVAEGVGGPDAERLAESLPAAVSVADRVPGEAVRLAQDAFAAGVNIAALI
MSMEG_5464|M.smegmatis_MC2_155 ------------------------AIAAALGSYRTAAALFAVLGGLAILT
.
MMAR_4767|M.marinum_M PPAQLCQQAA-------------
MUL_0338|M.ulcerans_Agy99 PPAQLCQQAA-------------
Mb0872|M.bovis_AF2122/97 AAPR-------------------
Rv0849|M.tuberculosis_H37Rv AAPR-------------------
Mflv_0900|M.gilvum_PYR-GCK ATPR-------------------
Mvan_5855|M.vanbaalenii_PYR-1 AVAR-------------------
MAB_1274|M.abscessus_ATCC_1997 ARA--------------------
MLBr_01562|M.leprae_Br4923 GEL--------------------
MAV_3702|M.avium_104 GEL--------------------
TH_3412|M.thermoresistible__bu GGAAVVVVAVVCATALRHLRPLD
MSMEG_5464|M.smegmatis_MC2_155 ARRS-------------------