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VGMPTTHEDPPPGVLKKAISASAIGNATEWFDYGIYAYGVSYISAAIFPGDAANATLLALMTFAVSFLVR PLGGFVWGPLGDRLGRKRVLAITIVLMAGATFCVALVPTYDMIGMWAPFLLVLLRMIQGFSTGGEYGGAA TFMAEYAPNRRRGLLGSFLEFGTLGGFSLGALLMLGCSLVLGDEQMHAWGWRLPFLVAAPLGLIGLYLRS RLEDTPVFRELEAKGGTEPETTTQFRDLLGRYWRPILQLGGLVVALNVVNYTLLSYMPTYLENRIGLSPD QSLIVPVIGMLSMMVFVPFAGLLSDRVGRKPLWWFSLIGLFVAGVPMFLLMGTNLWGAVIGFAVLGLLYV PQLATISATFPAMFPTQVRYAGFAIAYNVSTSLFGGTAPAINQWLTGETGDLLFPAYYMMGACVIGAIAL IKVPETARCPIGGTVTPGTEEAADPVPFEKQNA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5839 | - | - | 100% (453) | general substrate transporter |
| M. vanbaalenii PYR-1 | Mvan_4266 | - | 1e-99 | 43.84% (422) | general substrate transporter |
| M. vanbaalenii PYR-1 | Mvan_5748 | - | 1e-89 | 38.07% (415) | general substrate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3503c | kgtP | 1e-57 | 32.58% (399) | dicarboxylic acid transport integral membrane protein KgtP |
| M. gilvum PYR-GCK | Mflv_0953 | - | 0.0 | 86.22% (450) | general substrate transporter |
| M. tuberculosis H37Rv | Rv3476c | kgtP | 1e-57 | 32.83% (399) | dicarboxylic acid transport integral membrane protein KgtP |
| M. leprae Br4923 | MLBr_01562 | - | 3e-08 | 26.79% (209) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_2263c | - | 1e-145 | 59.44% (429) | major facilitator transporter |
| M. marinum M | MMAR_4238 | - | 9e-56 | 33.64% (431) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 4e-62 | 34.95% (412) | major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2486 | - | 0.0 | 82.92% (439) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_3400 | - | 0.0 | 76.91% (446) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_0949 | - | 4e-56 | 33.64% (431) | integral membrane transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3503c|M.bovis_AF2122/97 -----------------MTVSIAP--------PSRPSQAETRRAI---WN
Rv3476c|M.tuberculosis_H37Rv -----------------MTVSIAP--------PSRPSQAETRRAI---WN
Mvan_5839|M.vanbaalenii_PYR-1 ----------------------MG-------MPTTHEDPPPGVLK---KA
Mflv_0953|M.gilvum_PYR-GCK -----------------MDSRDAR-------PPTIEKEQPPAVLK---KA
MSMEG_2486|M.smegmatis_MC2_155 -----------------MGSRNGSENGSEHTSPPAVGDQPPAVVR---KA
TH_3400|M.thermoresistible__bu -----------------LTTERTDP----PQDPSVEQEQPPGVLR---KA
MAB_2263c|M.abscessus_ATCC_199 --------------MSSAGPREGETEPPPVPRPDFQSPEGRRQLH---RA
MMAR_4238|M.marinum_M -------------------------------------------MS---RV
MUL_0949|M.ulcerans_Agy99 -------------------------------------------MS---RV
MAV_4627|M.avium_104 --------------MAATLPAPAPAGLADGHPLDESAEQQRRRLR---IV
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mb3503c|M.bovis_AF2122/97 TIRGSSGNLVEWYDVYVYTVFATYFEDQFFDR--ADRNSTVYVYAIFAVT
Rv3476c|M.tuberculosis_H37Rv TIRGSSGNLVEWYDVYVYTVFATYFEDQFFDR--ADRNSTVYVYAIFAVT
Mvan_5839|M.vanbaalenii_PYR-1 ISASAIGNATEWFDYGIYAYGVSYISAAIFPG--DAANATLLALMTFAVS
Mflv_0953|M.gilvum_PYR-GCK IAASAIGNATEWFDYGIYAYGVTYISAAIFPG--DAANATLLALMTFAVS
MSMEG_2486|M.smegmatis_MC2_155 VAASAIGNATEWFDYGIYAYGVTYISAAIFPG--DAGTATLLALMTFAVS
TH_3400|M.thermoresistible__bu IAASAVGNATEWFDYGLYAYGVTYISVAIFPG--DGATATLLALMTFAVS
MAB_2263c|M.abscessus_ATCC_199 IAASAMGNATEWYDYGVYAATTTFLTQAFFP-----TLGTAFTMLGYAIS
MMAR_4238|M.marinum_M ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MUL_0949|M.ulcerans_Agy99 ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MAV_4627|M.avium_104 VAASLLGTTVEWYDFFLYATAAGLVFNKVFFPNESSLVGTLLAFATFAVG
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
. . : . : :
Mb3503c|M.bovis_AF2122/97 FVTRPVGSWFFG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRSSIGV
Rv3476c|M.tuberculosis_H37Rv FVTRPVGSWFLG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRSSIGV
Mvan_5839|M.vanbaalenii_PYR-1 FLVRPLGGFVWG-PLGDRLGRKRVLAITIVLMAGATFCVALVPTYDMIGM
Mflv_0953|M.gilvum_PYR-GCK FLVRPLGGFVWG-PLGDRLGRKRVLAMTILLMAGATFCVGLVPTYAAIGM
MSMEG_2486|M.smegmatis_MC2_155 FLVRPLGGFVWG-PLGDRLGRKRVLAITILMMAGATLCVGLVPTYASIGI
TH_3400|M.thermoresistible__bu FLVRPLGGFVWG-PLGDRLGRRQVLAITILLMAGATFCVGLVPSYDSIGL
MAB_2263c|M.abscessus_ATCC_199 FLLRPLGGMVWG-PLGDRLGRKSVMAITIVLMALSTTLIGILPSWATIGM
MMAR_4238|M.marinum_M FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGV
MUL_0949|M.ulcerans_Agy99 FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGV
MAV_4627|M.avium_104 FVMRPIGGLVFG-HIGDRIGRKRSLALTMLIMGGATALIGVLPTAAQIGA
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVA--------
:: * . * :.* **: : : :: .: .:
Mb3503c|M.bovis_AF2122/97 AAPILLILCRLVQGFATGGEYGT-----SVTYMSEAATRERRGYFSSFQY
Rv3476c|M.tuberculosis_H37Rv AAPILLILCRLVQGFATGGEYGT-----SATYMSEAATRERRGYFSSFQY
Mvan_5839|M.vanbaalenii_PYR-1 WAPFLLVLLRMIQGFSTGGEYGG-----AATFMAEYAPNRRRGLLGSFLE
Mflv_0953|M.gilvum_PYR-GCK WAPFLLVLLRMIQGFSTGGEYGG-----AATFMAEYSPSRRRGLLGSFLE
MSMEG_2486|M.smegmatis_MC2_155 WAPITLVVLRMIQGFSTGGEYGG-----AATFMAEYAPTRKRGFLGSFLE
TH_3400|M.thermoresistible__bu WAPVLMVILRMIQGFSTGGEYGG-----AATFMAEYAPSRRRGLLGSFLE
MAB_2263c|M.abscessus_ATCC_199 AAPALLILLRVIQGFSTGGEYGG-----AATFMAEFAPDKKRGKYGSFLE
MMAR_4238|M.marinum_M SAPLILVALRLLQGFAVGGEWAG-----SALLSIESAPAHKRGYYGMFTV
MUL_0949|M.ulcerans_Agy99 SAPLILVALRLLQGFAVGGEWAG-----SALLSIESAPAHKRGYYGMFTV
MAV_4627|M.avium_104 WAPVLLLVLRVLQGFALGGEWGG-----AVLLAVEHSPGDRRGRYGAVPQ
MLBr_01562|M.leprae_Br4923 WDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTA
:: *::**:. . :. : . . .
Mb3503c|M.bovis_AF2122/97 VTLVGGHVLAQFTLLV-------ILAVFT--REQVHEFGWRIGFAVGGGA
Rv3476c|M.tuberculosis_H37Rv VTLVGGHVLAQFTLLV-------ILAVFT--REQVHEFGWRIGFAVGGGA
Mvan_5839|M.vanbaalenii_PYR-1 FGTLGGFSLGALLMLG-------CSLVLG--DEQMHAWGWRLPFLVAAPL
Mflv_0953|M.gilvum_PYR-GCK FGTLAGFSCGALLMLG-------CSLVLG--DEDMQAWGWRLPFLVAAPL
MSMEG_2486|M.smegmatis_MC2_155 FGTLAGFSLGALLMLG-------CSLVLG--ENDMQAWGWRLPFLVAAPL
TH_3400|M.thermoresistible__bu FGTLAGFSLGALMMLG-------VSLMLS--DDQMNTWGWRVPFLIAAPL
MAB_2263c|M.abscessus_ATCC_199 FGTLGGFAVGAAFVLV-------LDATLS--DDAMHTWGWRIPFLVALPM
MMAR_4238|M.marinum_M LGGGVALVVSGLTFLG-------VNYTIGESSSAFLQWGWRVPFLLSALL
MUL_0949|M.ulcerans_Agy99 LGGGVALVVSGLTFLG-------VNYTIGESSSALLQWGWRVPFLLSALL
MAV_4627|M.avium_104 VGLALGLALGTGIFAF-------LQIVLG--PARFLSYGWRIGFLLSVLL
MLBr_01562|M.leprae_Br4923 IGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKL
. . . : . . : .
Mb3503c|M.bovis_AF2122/97 AIVVFWLRRTMDESLSQER--LTAIKAG-RDHDSGSLRELAT--------
Rv3476c|M.tuberculosis_H37Rv AIVVFWLRRTMDESLSQER--LTAIKAG-RDHDSGSLRELAT--------
Mvan_5839|M.vanbaalenii_PYR-1 GLIGLYLRSRLEDTPVFRE--LEAKGGT-EPETTTQFRDLLG--------
Mflv_0953|M.gilvum_PYR-GCK GLIGVYLRSRLEDTPVYRE--LEQEGRT-EESTSMQFRDLVV--------
MSMEG_2486|M.smegmatis_MC2_155 GLVGIYLRTRLEDTPVFRE--LAEKGGT-EEQATKAFRDLIV--------
TH_3400|M.thermoresistible__bu GLIGLYLRSRLDDTPIFRE--LQESDRE-EKSIWTEFKDLLV--------
MAB_2263c|M.abscessus_ATCC_199 GLIGWYLRSRLDDPPLFKE--MQEQEPEGRETAFERLRDLVR--------
MMAR_4238|M.marinum_M IAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC--------
MUL_0949|M.ulcerans_Agy99 IAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC--------
MAV_4627|M.avium_104 VAIGIVVRLRVEETPAFR------ELQDLQAASTVPIRDILRER------
MLBr_01562|M.leprae_Br4923 DAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVE
: . : :
Mb3503c|M.bovis_AF2122/97 ------------HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQ
Rv3476c|M.tuberculosis_H37Rv ------------HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQ
Mvan_5839|M.vanbaalenii_PYR-1 ------------RYWRPILQLGGLVVALNVVNYTLLSYMPTYLENRIGLS
Mflv_0953|M.gilvum_PYR-GCK ------------RYWRPILQMGGLVVALNVVNYTLLTYMPTYLENSIGLS
MSMEG_2486|M.smegmatis_MC2_155 ------------EYWRPILRLAGLVVALNVVNYTLLSYMPTYLENEIGLS
TH_3400|M.thermoresistible__bu ------------EYRGQILRLGGLVVALNVVNYTLLSYMPTYLQTSIGLS
MAB_2263c|M.abscessus_ATCC_199 ------------DYRRPMVVMMLLVIALNITNYTLLSYQPTYLKTRLGMS
MMAR_4238|M.marinum_M ------------RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYS
MUL_0949|M.ulcerans_Agy99 ------------RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYS
MAV_4627|M.avium_104 ------------RSRRNTVLGLLSRWAEGSAFNTWGVFAISYATGALGLN
MLBr_01562|M.leprae_Br4923 RTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYS
: * .
Mb3503c|M.bovis_AF2122/97 AMTATWINLVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLV
Rv3476c|M.tuberculosis_H37Rv AMTATWINLVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLV
Mvan_5839|M.vanbaalenii_PYR-1 PDQSLIVPVIGMLSMMVFVPFAGLLSDRVGRKP-LWWFSLIGLFVAGVPM
Mflv_0953|M.gilvum_PYR-GCK ADQSLMVPIIGMLAMMVFVPFAGLLSDRVGRKP-LWWFSLIGLFVAGIPA
MSMEG_2486|M.smegmatis_MC2_155 TDSSLVVPIIGMLTMMVFLPFAGRLSDRVGRKP-LWWFSLAGLFVAGLPM
TH_3400|M.thermoresistible__bu TDTALVVPIIGMLSMMVFLPFAGLLSDRFGRKP-MWWISLGGLLALVVPM
MAB_2263c|M.abscessus_ATCC_199 ETQGQIVILIGEVAMMAFLPFCGALSDRVGRKP-MWAFSLTGLLVLSLPM
MMAR_4238|M.marinum_M RNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVM
MUL_0949|M.ulcerans_Agy99 RNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVM
MAV_4627|M.avium_104 RVSVLIAVTIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFPAF
MLBr_01562|M.leprae_Br4923 ALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGW
: . . : .:.. : .
Mb3503c|M.bovis_AF2122/97 TYLPE------TRSPTMSFLLVAVGYVILTGYCSINA-------------
Rv3476c|M.tuberculosis_H37Rv TYLPE------TRSPTMSFLLVAVGYVILTGYCSINA-------------
Mvan_5839|M.vanbaalenii_PYR-1 FLLMG------TNLWGAVIGFAVLGLLYVPQLATISA-------------
Mflv_0953|M.gilvum_PYR-GCK FLLMG------TNLAGAVIGFAILGLLYVPQLATISA-------------
MSMEG_2486|M.smegmatis_MC2_155 FMLMG------TGMAGAVIGFAVLGLLYVPQLATISA-------------
TH_3400|M.thermoresistible__bu FMLMS------TSVPGAIIGFAVLGLLYVPQLATISA-------------
MAB_2263c|M.abscessus_ATCC_199 FWLMG------QGFGWAIVGFAVLGLLYIPQLSTITA-------------
MMAR_4238|M.marinum_M PLIGS------GDTVGFTVALLGLY-AVAASGFGPAA-------------
MUL_0949|M.ulcerans_Agy99 PLIGS------GDTVGFTVALLGLY-AVAASGFGPAA-------------
MAV_4627|M.avium_104 ALFGT------KKLLWFGLAMVIVFGVVHALFYGAQG-------------
MLBr_01562|M.leprae_Br4923 AFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAI
: . : . .
Mb3503c|M.bovis_AF2122/97 LVKSELFPAHVRALGVGVGYALANSVFGGTAP----LIYQALKERDQVPM
Rv3476c|M.tuberculosis_H37Rv LVKSELFPAHVRALGVGVGYALANSVFGGTAP----LIYQALKERDQVPM
Mvan_5839|M.vanbaalenii_PYR-1 TFP-AMFPTQVRYAGFAIAYNVSTSLFGGTAP----AINQWLTGETGDLL
Mflv_0953|M.gilvum_PYR-GCK TFP-AMFPTQVRYAGFAIAYNVSTSIFGGTAP----AVNDWLVGATGDNL
MSMEG_2486|M.smegmatis_MC2_155 TFP-AMFPTHVRYAGFAIAYNVSTSLFGGTAP----AVNEWLIGRTGDGL
TH_3400|M.thermoresistible__bu TFP-AMFPTHVRYAGFAIAYNVSTSLFGGTAP----AANDWLIQQTGNNL
MAB_2263c|M.abscessus_ATCC_199 TFP-CMFPTQVRYAGFAISYNLSTAAFGGTAP----LVNDLVVARTGWDL
MMAR_4238|M.marinum_M SLIPELFATRYRYTGTALALNVAGIVGGAAPP----LIAGTLLASYGSSA
MUL_0949|M.ulcerans_Agy99 SLIPELFATRYRYTGTALALNVAGIVGGAAPP----LIAGTLLASYGSSA
MAV_4627|M.avium_104 TLYSALYPTNTRYTGLSFVYQFSGVYASGVTP----MILTALIAALGG-A
MLBr_01562|M.leprae_Br4923 ALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYT
. .... :
Mb3503c|M.bovis_AF2122/97 FIAYVTACIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA----------
Rv3476c|M.tuberculosis_H37Rv FIAYVTACIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA----------
Mvan_5839|M.vanbaalenii_PYR-1 FPAYYMMGACVIGAIALIKVPETARCPIGGTVTPGTEEAADPVPFEKQNA
Mflv_0953|M.gilvum_PYR-GCK VPAYYMMGACVIGALALIRIPETTRCPLNGTATPGTDEAPAPVEYEKSSA
MSMEG_2486|M.smegmatis_MC2_155 IPAYYMMAACVVGAIALISVPETSRCPINGTHIPGTAEAPRALSYHARPT
TH_3400|M.thermoresistible__bu MPAFYMMAACLVGMLALVKLPETARCPIGGTEIPGTEDAPPPVEYDLVGN
MAB_2263c|M.abscessus_ATCC_199 FPAAYLMVACVVGLCALPFLIETAGASIAGTEIP-CNEAAVPTDTVRA--
MMAR_4238|M.marinum_M VGLMMTALVAAS-LLCTYLLPETAGAPLTAA-------------------
MUL_0949|M.ulcerans_Agy99 VGLMMTALVAAS-LLCTYLLPETAGAPLTAA-------------------
MAV_4627|M.avium_104 PWLACGYLVATA-VISVLATALIRDRDLYL--------------------
MLBr_01562|M.leprae_Br4923 YGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL--------
Mb3503c|M.bovis_AF2122/97 ---
Rv3476c|M.tuberculosis_H37Rv ---
Mvan_5839|M.vanbaalenii_PYR-1 ---
Mflv_0953|M.gilvum_PYR-GCK ---
MSMEG_2486|M.smegmatis_MC2_155 APA
TH_3400|M.thermoresistible__bu R--
MAB_2263c|M.abscessus_ATCC_199 ---
MMAR_4238|M.marinum_M ---
MUL_0949|M.ulcerans_Agy99 ---
MAV_4627|M.avium_104 ---
MLBr_01562|M.leprae_Br4923 ---