For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3400 | - | - | 100% (463) | General substrate transporter |
| M. thermoresistible (build 8) | TH_3722 | - | e-100 | 43.67% (442) | PUTATIVE General substrate transporter |
| M. thermoresistible (build 8) | TH_4243 | - | 8e-69 | 32.95% (440) | PUTATIVE General substrate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1232 | - | 4e-56 | 33.25% (424) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_0953 | - | 0.0 | 76.46% (446) | general substrate transporter |
| M. tuberculosis H37Rv | Rv1200 | - | 4e-56 | 33.25% (424) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01562 | - | 6e-06 | 25.48% (157) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_2263c | - | 1e-151 | 58.67% (450) | major facilitator transporter |
| M. marinum M | MMAR_4238 | - | 1e-59 | 33.41% (431) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 3e-63 | 33.80% (429) | major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_1477 | - | 0.0 | 77.46% (448) | major facilitator superfamily protein |
| M. ulcerans Agy99 | MUL_0949 | - | 4e-60 | 33.41% (431) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_5839 | - | 0.0 | 76.91% (446) | general substrate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1232|M.bovis_AF2122/97 ---------------------------------------MKRVALACLVG
Rv1200|M.tuberculosis_H37Rv ---------------------------------------MKRVALACLVG
MMAR_4238|M.marinum_M ---------------------------------------MSRVALACVVG
MUL_0949|M.ulcerans_Agy99 ---------------------------------------MSRVALACVVG
MAV_4627|M.avium_104 ---MAATLPAP-------APAGLADGHPLDESAEQQRRRLRIVVAASLLG
Mflv_0953|M.gilvum_PYR-GCK ---MDSR------------DARPPTIEKEQ-----PPAVLKKAIAASAIG
Mvan_5839|M.vanbaalenii_PYR-1 --------------------MGMPTTHEDP-----PPGVLKKAISASAIG
MSMEG_1477|M.smegmatis_MC2_155 ---MDSKEADASKPSQADADQQAPTAHAEEVKA--PPEVVKRAVAASAVG
TH_3400|M.thermoresistible__bu ---LTTERTD---------PPQDPSVEQEQ-----PPGVLRKAIAASAVG
MAB_2263c|M.abscessus_ATCC_199 ---MSSAGPR-------EGETEPPPVPRPDFQSPEGRRQLHRAIAASAMG
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
. ..
Mb1232|M.bovis_AF2122/97 SAIEFYDFLIYGTAAALVF------PTVFFPHLDPTVAAVASMGTFAVAF
Rv1200|M.tuberculosis_H37Rv SAIEFYDFLIYGTAAALVF------PTVFFPHLDPTVAAVASMGTFAVAF
MMAR_4238|M.marinum_M STVEYYDFCIYGTAAALVF------PAVFYPGLSPALATIASMGTFATAF
MUL_0949|M.ulcerans_Agy99 STVEYYDFCIYGTAAALVF------PAVFYPGLSPALATIASMGTFATAF
MAV_4627|M.avium_104 TTVEWYDFFLYATAAGLVF------NKVFFPNESSLVGTLLAFATFAVGF
Mflv_0953|M.gilvum_PYR-GCK NATEWFDYGIYAYGVTYIS------AAIFPG--DAANATLLALMTFAVSF
Mvan_5839|M.vanbaalenii_PYR-1 NATEWFDYGIYAYGVSYIS------AAIFPG--DAANATLLALMTFAVSF
MSMEG_1477|M.smegmatis_MC2_155 NFTEWFDYGIYAYGVSYIS------AAIFPG--DGKSATLLALMTFAVSF
TH_3400|M.thermoresistible__bu NATEWFDYGLYAYGVTYIS------VAIFPG--DGATATLLALMTFAVSF
MAB_2263c|M.abscessus_ATCC_199 NATEWYDYGVYAATTTFLT------QAFFP-----TLGTAFTMLGYAISF
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
.: : : . . : :.
Mb1232|M.bovis_AF2122/97 LSRPFGAAVFG--YFGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIGA
Rv1200|M.tuberculosis_H37Rv LSRPFGAAVFG--YFGDRLGRKKTLVATLLIMGLATVTVGLVPTTVAIGA
MMAR_4238|M.marinum_M LSRPLGAAVFG--HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGV
MUL_0949|M.ulcerans_Agy99 LSRPLGAAVFG--HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTATIGV
MAV_4627|M.avium_104 VMRPIGGLVFG--HIGDRIGRKRSLALTMLIMGGATALIGVLPTAAQIGA
Mflv_0953|M.gilvum_PYR-GCK LVRPLGGFVWG--PLGDRLGRKRVLAMTILLMAGATFCVGLVPTYAAIGM
Mvan_5839|M.vanbaalenii_PYR-1 LVRPLGGFVWG--PLGDRLGRKRVLAITIVLMAGATFCVALVPTYDMIGM
MSMEG_1477|M.smegmatis_MC2_155 LVRPLGGLVWG--PLGDRIGRKQVLAITILLMAGATLCVGLVPPYATIGV
TH_3400|M.thermoresistible__bu LVRPLGGFVWG--PLGDRLGRRQVLAITILLMAGATFCVGLVPSYDSIGL
MAB_2263c|M.abscessus_ATCC_199 LLRPLGGMVWG--PLGDRLGRKSVMAITIVLMALSTTLIGILPSWATIGM
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVA--------
.:*. : :** :**: : : :: :: .:
Mb1232|M.bovis_AF2122/97 AAPLILTTMRLLQGFAVGGEWAG-----SALLSAEYAPASKRGWYGMFTV
Rv1200|M.tuberculosis_H37Rv AAPLILTTMRLLQGFAVGGEWAG-----SALLSAEYAPASKRGWYGMFTV
MMAR_4238|M.marinum_M SAPLILVALRLLQGFAVGGEWAG-----SALLSIESAPAHKRGYYGMFTV
MUL_0949|M.ulcerans_Agy99 SAPLILVALRLLQGFAVGGEWAG-----SALLSIESAPAHKRGYYGMFTV
MAV_4627|M.avium_104 WAPVLLLVLRVLQGFALGGEWGG-----AVLLAVEHSPGDRRGRYGAVPQ
Mflv_0953|M.gilvum_PYR-GCK WAPFLLVLLRMIQGFSTGGEYGG-----AATFMAEYSPSRRRGLLGSFLE
Mvan_5839|M.vanbaalenii_PYR-1 WAPFLLVLLRMIQGFSTGGEYGG-----AATFMAEYAPNRRRGLLGSFLE
MSMEG_1477|M.smegmatis_MC2_155 AAPILMVVLRMIQGFSTGGEYGG-----AATFMAEYSPSRRRGLFGSFLE
TH_3400|M.thermoresistible__bu WAPVLMVILRMIQGFSTGGEYGG-----AATFMAEYAPSRRRGLLGSFLE
MAB_2263c|M.abscessus_ATCC_199 AAPALLILLRVIQGFSTGGEYGG-----AATFMAEFAPDKKRGKYGSFLE
MLBr_01562|M.leprae_Br4923 WDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTA
: *::**:. . :. : : . . .
Mb1232|M.bovis_AF2122/97 VGGGIALVLTSLTFLG-------VNYTIGESSPTFMQWGWRIPFLVSAAL
Rv1200|M.tuberculosis_H37Rv VGGGIALVLTSLTFLG-------VNYTIGESSPTFMQWGWRIPFLVSAAL
MMAR_4238|M.marinum_M LGGGVALVVSGLTFLG-------VNYTIGESSSAFLQWGWRVPFLLSALL
MUL_0949|M.ulcerans_Agy99 LGGGVALVVSGLTFLG-------VNYTIGESSSALLQWGWRVPFLLSALL
MAV_4627|M.avium_104 VGLALGLALGTGIFAF-------LQIVLG--PARFLSYGWRIGFLLSVLL
Mflv_0953|M.gilvum_PYR-GCK FGTLAGFSCGALLMLG-------CSLVLG--DEDMQAWGWRLPFLVAAPL
Mvan_5839|M.vanbaalenii_PYR-1 FGTLGGFSLGALLMLG-------CSLVLG--DEQMHAWGWRLPFLVAAPL
MSMEG_1477|M.smegmatis_MC2_155 FGTLAGFSFGALLMLG-------FSLLLS--DDQMGSWGWRLPFLVAAPL
TH_3400|M.thermoresistible__bu FGTLAGFSLGALMMLG-------VSLMLS--DDQMNTWGWRVPFLIAAPL
MAB_2263c|M.abscessus_ATCC_199 FGTLGGFAVGAAFVLV-------LDATLS--DDAMHTWGWRIPFLVALPM
MLBr_01562|M.leprae_Br4923 IGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKL
.* .: . :. : . : . :
Mb1232|M.bovis_AF2122/97 IAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLR--------
Rv1200|M.tuberculosis_H37Rv IAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLR--------
MMAR_4238|M.marinum_M IAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC--------
MUL_0949|M.ulcerans_Agy99 IAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC--------
MAV_4627|M.avium_104 VAIGIVVRLRVEETPAFREL------QDLQAASTVPIRDILRER------
Mflv_0953|M.gilvum_PYR-GCK GLIGVYLRSRLEDTPVYREL--EQEGRT-EESTSMQFRDLVV--------
Mvan_5839|M.vanbaalenii_PYR-1 GLIGLYLRSRLEDTPVFREL--EAKGGT-EPETTTQFRDLLG--------
MSMEG_1477|M.smegmatis_MC2_155 GLIGVYLRSRLEDTPIYREL--EESGES-EEHPTGEFKALVV--------
TH_3400|M.thermoresistible__bu GLIGLYLRSRLDDTPIFREL--QESDRE-EKSIWTEFKDLLV--------
MAB_2263c|M.abscessus_ATCC_199 GLIGWYLRSRLDDPPLFKEM--QEQEPEGRETAFERLRDLVR--------
MLBr_01562|M.leprae_Br4923 DAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVE
. : .. : : ::
Mb1232|M.bovis_AF2122/97 ------------RQRREIVLAAGSAVCCFGFVYLASTYLASYAQTRLGYS
Rv1200|M.tuberculosis_H37Rv ------------RQRREIVLAAGSAVCCFGFVYLASTYLASYAQTRLGYS
MMAR_4238|M.marinum_M ------------RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYS
MUL_0949|M.ulcerans_Agy99 ------------RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYS
MAV_4627|M.avium_104 ------------RSRRNTVLGLLSRWAEGSAFNTWGVFAISYATGALGLN
Mflv_0953|M.gilvum_PYR-GCK ------------RYWRPILQMGGLVVALNVVNYTLLTYMPTYLENSIGLS
Mvan_5839|M.vanbaalenii_PYR-1 ------------RYWRPILQLGGLVVALNVVNYTLLSYMPTYLENRIGLS
MSMEG_1477|M.smegmatis_MC2_155 ------------DYWSPILRLGGLVVALNVVNYTLLTYMPTYLESAIGLS
TH_3400|M.thermoresistible__bu ------------EYRGQILRLGGLVVALNVVNYTLLSYMPTYLQTSIGLS
MAB_2263c|M.abscessus_ATCC_199 ------------DYRRPMVVMMLLVIALNITNYTLLSYQPTYLKTRLGMS
MLBr_01562|M.leprae_Br4923 RTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYS
: * :* .
Mb1232|M.bovis_AF2122/97 RGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLVM
Rv1200|M.tuberculosis_H37Rv RGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLVM
MMAR_4238|M.marinum_M RNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVM
MUL_0949|M.ulcerans_Agy99 RNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVM
MAV_4627|M.avium_104 RVSVLIAVTIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFPAF
Mflv_0953|M.gilvum_PYR-GCK ADQSLMVPIIGMLAMMVFVPFAGLLSDRVGRKPLWWFSLIGLFVAGIPAF
Mvan_5839|M.vanbaalenii_PYR-1 PDQSLIVPVIGMLSMMVFVPFAGLLSDRVGRKPLWWFSLIGLFVAGVPMF
MSMEG_1477|M.smegmatis_MC2_155 TDQSLVVPIIGMLSMMVFLPFAGRISDRVGRKPMWWFSVVGLFVAGVPMF
TH_3400|M.thermoresistible__bu TDTALVVPIIGMLSMMVFLPFAGLLSDRFGRKPMWWISLGGLLALVVPMF
MAB_2263c|M.abscessus_ATCC_199 ETQGQIVILIGEVAMMAFLPFCGALSDRVGRKPMWAFSLTGLLVLSLPMF
MLBr_01562|M.leprae_Br4923 ALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGW
. : ... : .:.. : : .
Mb1232|M.bovis_AF2122/97 PLIDSGSPSLFAVAVVGMY-AIGGFGFGPTASFIPELFATSYRYTGSALA
Rv1200|M.tuberculosis_H37Rv PLIDSGSPSLFAVAVVGMY-AIGGFGFGPTASFIPELFATSYRYTGSALA
MMAR_4238|M.marinum_M PLIGSGDTVGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALA
MUL_0949|M.ulcerans_Agy99 PLIGSGDTVGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALA
MAV_4627|M.avium_104 ALFGTKKLLWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTGLSFV
Mflv_0953|M.gilvum_PYR-GCK LLMGTN--LAGAVIGFAILGLLYVPQLATISATFPAMFPTQVRYAGFAIA
Mvan_5839|M.vanbaalenii_PYR-1 LLMGTN--LWGAVIGFAVLGLLYVPQLATISATFPAMFPTQVRYAGFAIA
MSMEG_1477|M.smegmatis_MC2_155 MLMSTN--LVGAIIGFAVLGLLYVPQLATISATFPAMFPTQVRFAGFAIA
TH_3400|M.thermoresistible__bu MLMSTS--VPGAIIGFAVLGLLYVPQLATISATFPAMFPTHVRYAGFAIA
MAB_2263c|M.abscessus_ATCC_199 WLMGQG--FGWAIVGFAVLGLLYIPQLSTITATFPCMFPTQVRYAGFAIS
MLBr_01562|M.leprae_Br4923 AFMNRGVPYFPNLLAPIVVGGIGIG-MAVVPLTLSAIAGVGFDRIGPVSA
::. : : : . . : . *
Mb1232|M.bovis_AF2122/97 ANLAGVAGG-----------------------ALPPVIAGALVATYG--S
Rv1200|M.tuberculosis_H37Rv ANLAGVAGG-----------------------ALPPVIAGALVATYG--S
MMAR_4238|M.marinum_M LNVAGIVGG-----------------------AAPPLIAGTLLASYG--S
MUL_0949|M.ulcerans_Agy99 LNVAGIVGG-----------------------AAPPLIAGTLLASYG--S
MAV_4627|M.avium_104 YQFSGVYAS-----------------------GVTPMILTALIAALGGAP
Mflv_0953|M.gilvum_PYR-GCK YNVSTSIFG-----------------------GTAPAVNDWLVGATG-DN
Mvan_5839|M.vanbaalenii_PYR-1 YNVSTSLFG-----------------------GTAPAINQWLTGETG-DL
MSMEG_1477|M.smegmatis_MC2_155 YNVSTSIFG-----------------------GTAPAINDWLVNLTG-DN
TH_3400|M.thermoresistible__bu YNVSTSLFG-----------------------GTAPAANDWLIQQTG-NN
MAB_2263c|M.abscessus_ATCC_199 YNLSTAAFG-----------------------GTAPLVNDLVVARTG-WD
MLBr_01562|M.leprae_Br4923 IALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGY
. . . .
Mb1232|M.bovis_AF2122/97 WAIGVMLAILALISLVCTYRLPETAGSALVSR------------------
Rv1200|M.tuberculosis_H37Rv WAIGVMLAILALISLVCTYRLPETAGSALVSR------------------
MMAR_4238|M.marinum_M SAVGLMMTALVAASLLCTYLLPETAGAPLTAA------------------
MUL_0949|M.ulcerans_Agy99 SAVGLMMTALVAASLLCTYLLPETAGAPLTAA------------------
MAV_4627|M.avium_104 WLACGYLVATAVISVLATALIRDRD---LYL-------------------
Mflv_0953|M.gilvum_PYR-GCK LVPAYYMMGACVIGALALIRIPETTRCPLNGTATPGTDEAPAPVEYEKSS
Mvan_5839|M.vanbaalenii_PYR-1 LFPAYYMMGACVIGAIALIKVPETARCPIGGTVTPGTEEAADPVPFEKQN
MSMEG_1477|M.smegmatis_MC2_155 LVPAYYMMVACVIGAISLVRMPETARCPINGTEIPGTPEAPPQLDYKEPA
TH_3400|M.thermoresistible__bu LMPAFYMMAACLVGMLALVKLPETARCPIGGTEIPGTEDAPPPVEYDLVG
MAB_2263c|M.abscessus_ATCC_199 LFPAAYLMVACVVGLCALPFLIETAGASIAGTEIP-CNEAAVPTDTVRA-
MLBr_01562|M.leprae_Br4923 TYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL-------
: . :
Mb1232|M.bovis_AF2122/97 ---
Rv1200|M.tuberculosis_H37Rv ---
MMAR_4238|M.marinum_M ---
MUL_0949|M.ulcerans_Agy99 ---
MAV_4627|M.avium_104 ---
Mflv_0953|M.gilvum_PYR-GCK A--
Mvan_5839|M.vanbaalenii_PYR-1 A--
MSMEG_1477|M.smegmatis_MC2_155 HAS
TH_3400|M.thermoresistible__bu NR-
MAB_2263c|M.abscessus_ATCC_199 ---
MLBr_01562|M.leprae_Br4923 ---