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PAGTPLYMTIAADVRDRIATEQLGPHTLLPSERELAEQHGVSRMTARQALSLLESEGVVYRKPPRGTFVA EPRVRFHVGSFSEEVARMGRRPAARQLWAEHQLASPAVRRALGLAEGAAVHVFHRLRSVDDVPFALETTY LPADLTPGILEITDEGSLWAVLRSRYGVELARSTAVLESIVLDDASSMQLGVRAGSAGTLLTRTTVDTAG RCVEYARDVYRADRASFEVSEELRTPRLSAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3927 | - | - | 100% (242) | UbiC transcription regulator-associated domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2288 | - | 1e-26 | 35.65% (230) | UbiC transcription regulator-associated domain-containing |
| M. vanbaalenii PYR-1 | Mvan_5574 | - | 3e-24 | 34.33% (233) | UbiC transcription regulator-associated domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 3e-18 | 28.99% (238) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2652 | - | 1e-120 | 88.02% (242) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0792c | - | 3e-18 | 28.99% (238) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 2e-27 | 37.50% (224) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 3e-18 | 29.91% (234) | GntR family transcriptional regulator |
| M. avium 104 | MAV_5032 | - | 1e-16 | 31.86% (204) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0268 | - | 3e-24 | 33.49% (215) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3932 | - | 2e-18 | 29.91% (234) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 1e-17 | 29.49% (234) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
Mvan_3927|M.vanbaalenii_PYR-1 ------------------MPAG-TPLYMTIAADVRDRIATEQLGPHTLLP
Mflv_2652|M.gilvum_PYR-GCK ----MSTTEADLRGYSAKMPAG-TPLYMSIASDVRDLIASEALGPHTLLP
MAB_0953|M.abscessus_ATCC_1997 ----------------MEESEG-GPVAEDVRRRILSMLAQGTLHPGSRLG
MSMEG_0268|M.smegmatis_MC2_155 ----------------MPVQ------SEELRRRLVADINAGT--PGAKLG
MAV_5032|M.avium_104 ----------------------------MLRSQILEGAYGGLAAARPALP
TH_3932|M.thermoresistible__bu ------MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERARPGDRLP
: *
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVR--RQGLGTFVADPVEQELS
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVR--RQGLGTFVADPVEQELS
MMAR_2560|M.marinum_M TEQELIARSGVSRSTVRAAVGILEDEGWLVR--RQGLGTFVAEPVKQDLE
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVR--RQGLGTFVAEPVEQDLE
Mvan_3927|M.vanbaalenii_PYR-1 SERELAEQHGVSRMTARQALSLLESEGVVYRKPPR--GTFVAEPRVRFHV
Mflv_2652|M.gilvum_PYR-GCK SERELAEQHGVSRMTARQALSLLESEGVVYRKPPR--GTFVAEPRVRFHI
MAB_0953|M.abscessus_ATCC_1997 SEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRNV
MSMEG_0268|M.smegmatis_MC2_155 SERDLAEKYGTSRSSLRQVLAALEEAGLVHRVIGRSGGIFISHGQVERNL
MAV_5032|M.avium_104 SESALAAELGVSRNAIREALELLRGEGLITR--VQGSGTFVTGAKLRQDL
TH_3932|M.thermoresistible__bu SEAELSGQFGVNRLTVRRALHELAQRGIIET--VHGRGSFVARQPVRYRL
:* : . . .* : * .: * * : : * *: .
Mb0816c|M.bovis_AF2122/97 CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
Rv0792c|M.tuberculosis_H37Rv CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
MMAR_2560|M.marinum_M SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRSE---VLRIQR
MUL_3201|M.ulcerans_Agy99 SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRSE---VLRIQR
Mvan_3927|M.vanbaalenii_PYR-1 GSFS---EEVARMGRRPAARQLWAEHQLASPAVRRALGLAEGAAVHVFHR
Mflv_2652|M.gilvum_PYR-GCK GSFS---EEVARMGRRPAAQLLWAEHQAATPAVRRALGLDEGAAVHVFHR
MAB_0953|M.abscessus_ATCC_1997 AELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVRR
MSMEG_0268|M.smegmatis_MC2_155 SDVVGVPAFLANQGYVAGTRILSTRITTPDQTTRTALRLGPGEYVVEIQR
MAV_5032|M.avium_104 NRLKGLAESLAGHRLPVENKVLSIRESTATPFVAAKLQLPENAPILFIER
TH_3932|M.thermoresistible__bu SATRDASFTRGMRELGHPVRIEVLG-AETTRCRRLRTELHTAGEVLTTTT
. :
Mb0816c|M.bovis_AF2122/97 RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
Rv0792c|M.tuberculosis_H37Rv RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
MMAR_2560|M.marinum_M RYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATATTYTMWEQRLGVRI
MUL_3201|M.ulcerans_Agy99 RYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTATTYTMWEQRLGVRI
Mvan_3927|M.vanbaalenii_PYR-1 LRSVDDVPFALETTYLPADLTPGILEITDEG-----SLWAVLRSRYGVEL
Mflv_2652|M.gilvum_PYR-GCK LRSVDEVPFALETTFLPAELTPGILDMTEDG-----SLWAVLRSKYAIEL
MAB_0953|M.abscessus_ATCC_1997 LRYADGVPLSVDTAYFPAELVPDLLEQPLGG-----SLYELCQVRYGLQA
MSMEG_0268|M.smegmatis_MC2_155 VRLADGSPISLEQAQFPAEKFPGLLEQQLGG-----SLYEVLESQYGLVP
MAV_5032|M.avium_104 LRSVGGLPLSLDTTSLRIGAIRIDADLDKQD------VFALIEQELGERL
TH_3932|M.thermoresistible__bu LRHVDGQPWSVSVTSIALDRFPGIAQQWSGS----TSLFDFLWQTFGVRM
. * :: : : : . .
Mb0816c|M.bovis_AF2122/97 AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
Rv0792c|M.tuberculosis_H37Rv AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
MMAR_2560|M.marinum_M SSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
MUL_3201|M.ulcerans_Agy99 SSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
Mvan_3927|M.vanbaalenii_PYR-1 ARSTAVLESIVLDDASSMQLGVRAGSAGTLLTRTTVDTAGRCVEYARDVY
Mflv_2652|M.gilvum_PYR-GCK ARTTAVLESIVLDDASSVQLGVRAGSAGTLLTRTTYDSADRCVEYARDVY
MAB_0953|M.abscessus_ATCC_1997 DSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRPFEFSYDLF
MSMEG_0268|M.smegmatis_MC2_155 GRADERIEAVNATSNEATLLGIKPKAALLLITRVTFDQTGTPYEFSRDLF
MAV_5032|M.avium_104 GWAEITVESVLADPNTATLLQIRTGAPLLLLHRLTHLRDGTPFDLETVRY
TH_3932|M.thermoresistible__bu RRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHGAPVAVVRHRF
: . : * : . : . . .
Mb0816c|M.bovis_AF2122/97 RPERYQFSVTLPRTLPGSGAGIIEKRDFA-----------------
Rv0792c|M.tuberculosis_H37Rv RPERYQFSVTLPRTLPGSGAGIIEKRDFA-----------------
MMAR_2560|M.marinum_M RPERYEFCVTLPRTMPGQRAGMTER---------------------
MUL_3201|M.ulcerans_Agy99 RPERYEFCVTLPRTMPGQRAGMTER---------------------
Mvan_3927|M.vanbaalenii_PYR-1 RADRASFEVSEELRTPRLSAV-------------------------
Mflv_2652|M.gilvum_PYR-GCK RADRAAFEVSEELRSQRLSAV-------------------------
MAB_0953|M.abscessus_ATCC_1997 RADRVRLTATMTS-AVAQESRGVDGKVERVVSRLAAHRRPDDTLLA
MSMEG_0268|M.smegmatis_MC2_155 RGDRTALAVTAKGRGIAAASN--SGTDNRTAS-VTLHRQVG-----
MAV_5032|M.avium_104 RGDRCSLVTTATREDAPPQ---------------------------
TH_3932|M.thermoresistible__bu RGDRVELTVDLA----------------------------------
* :* : .