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LRSQILEGAYGGLAAARPALPSESALAAELGVSRNAIREALELLRGEGLITRVQGSGTFVTGAKLRQDLN RLKGLAESLAGHRLPVENKVLSIRESTATPFVAAKLQLPENAPILFIERLRSVGGLPLSLDTTSLRIGAI RIDADLDKQDVFALIEQELGERLGWAEITVESVLADPNTATLLQIRTGAPLLLLHRLTHLRDGTPFDLET VRYRGDRCSLVTTATREDAPPQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5032 | - | - | 100% (233) | GntR-family protein transcriptional regulator |
| M. avium 104 | MAV_3402 | - | 8e-41 | 47.53% (223) | GntR-family protein transcriptional regulator |
| M. avium 104 | MAV_0738 | - | 8e-12 | 27.40% (219) | mercuric reductase/transcriptional regulator, fusion |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 2e-16 | 28.77% (212) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1234 | - | 4e-17 | 28.82% (229) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 2e-16 | 28.77% (212) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2239 | - | 7e-48 | 50.00% (230) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 1e-16 | 30.77% (234) | GntR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1227 | - | 1e-103 | 80.77% (234) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3932 | - | 2e-16 | 31.42% (226) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 7e-17 | 31.20% (234) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5574 | - | 7e-18 | 28.82% (229) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5032|M.avium_104 ----------------------------MLRSQILEGAYGGLAA--ARPA
MSMEG_1227|M.smegmatis_MC2_155 ----------------------------MLRGKILDGVYGGLAA--ARPM
MAB_2239|M.abscessus_ATCC_1997 -----------MAAAEPTPLRRPRADQARLVADVLRHQIHAGGY--AEGG
Mb0816c|M.bovis_AF2122/97 MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLP--RGGR
Rv0792c|M.tuberculosis_H37Rv MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLP--RGGR
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALS--PGSR
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALS--PGSR
Mflv_1234|M.gilvum_PYR-GCK --------------MVEPIWRRRGGPVPTQTEDLRRRIVADINAGKPGTK
Mvan_5574|M.vanbaalenii_PYR-1 --------------------------MPTQTEDLRRRIVSDINAGVPGTK
TH_3932|M.thermoresistible__bu ------MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERAR--PGDR
:
MAV_5032|M.avium_104 LPSESALAAELGVSRNAIREALELLRGEGLITRVQGS--GTFVTGAKLRQ
MSMEG_1227|M.smegmatis_MC2_155 LPPENELAAEFGVSRNAIREALELLRGEGLITRVQGA--GTFVTGAKLSQ
MAB_2239|M.abscessus_ATCC_1997 LPSEHALAAEFFVSRNTVREALTTLKDEGLIERGPRT--GTHVALRKYEH
Mb0816c|M.bovis_AF2122/97 LPSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGL--GTFVADPVEQE
Rv0792c|M.tuberculosis_H37Rv LPSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGL--GTFVADPVEQE
MMAR_2560|M.marinum_M LPTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGL--GTFVAEPVKQD
MUL_3201|M.ulcerans_Agy99 LPTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGL--GTFVAEPVEQD
Mflv_1234|M.gilvum_PYR-GCK LGSERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRSGGIFISHAQVQR
Mvan_5574|M.vanbaalenii_PYR-1 LGSERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRAGGIFISHAQVQR
TH_3932|M.thermoresistible__bu LPSEAELSGQFGVNRLTVRRALHELAQRGIIETVHGR--GSFVARQPVRY
* .* * . .* ::* .: * * : * .::
MAV_5032|M.avium_104 DLNRLK--GLAESLAGHRLPVENKVLSIRESTATPFVAAKLQLPENAPIL
MSMEG_1227|M.smegmatis_MC2_155 RIDRLE--GLAESLAGHQLPVENTVLSVRESVASPFVAAKLQLPEGAPIL
MAB_2239|M.abscessus_ATCC_1997 GLDALL--GLKETFKGYG-EVRNEVRVIQEVNAPPAVAHRLRLDPGARVI
Mb0816c|M.bovis_AF2122/97 LSCGVR--TITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VL
Rv0792c|M.tuberculosis_H37Rv LSCGVR--TITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VL
MMAR_2560|M.marinum_M LESGVR--TITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRSE---VL
MUL_3201|M.ulcerans_Agy99 LESGVR--TITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRSE---VL
Mflv_1234|M.gilvum_PYR-GCK SLTDVV--GVPAFLASQGYVAGTRVLSTKMTAPDATTQQALGIAADDFVI
Mvan_5574|M.vanbaalenii_PYR-1 SLTDVV--GVPAFLASQGYVAGTRVLSTKICAPDSATQQALKIGADDFVI
TH_3932|M.thermoresistible__bu RLSATRDASFTRGMRELGHPVRIEVLGAETTRCRRLRTELHTAGE---VL
. : * ::
MAV_5032|M.avium_104 FIERLRSVGGLPLSLDTTSLR--IGAIRIDADLD----KQDVFALIEQEL
MSMEG_1227|M.smegmatis_MC2_155 FIERLRSVGGVPLSLDTTSLR--LGAVSVDDNLD----RQDVFALIEREL
MAB_2239|M.abscessus_ATCC_1997 FIERLRYLGDLPLSLDKTYLTPDVGEAVIEHQLE----TNDVFALIERVT
Mb0816c|M.bovis_AF2122/97 CIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRL
Rv0792c|M.tuberculosis_H37Rv CIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRL
MMAR_2560|M.marinum_M RIQRRYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATATTYTMWEQRL
MUL_3201|M.ulcerans_Agy99 RIQRRYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTATTYTMWEQRL
Mflv_1234|M.gilvum_PYR-GCK EIQRLRLADGSPISLELAQFPAEAFPGLLEQQLG-----GSLYEILESEY
Mvan_5574|M.vanbaalenii_PYR-1 EIQRLRLADGSPISLELAQFPADAFPGLLEQQLG-----GSLYEILESQY
TH_3932|M.thermoresistible__bu TTTTLRHVDGQPWSVSVTSIALDRFPGIAQQWSG----STSLFDFLWQTF
.. * :: : : : :
MAV_5032|M.avium_104 GERLGWAEITVESVLADPNTATLLQIRTGAPLLLLHRLTHLRDGTPFDLE
MSMEG_1227|M.smegmatis_MC2_155 GMRLGWAEMTVESVSADADTAKLLQIRSGAPLLLLHRLTHLEDGTPFDFE
MAB_2239|M.abscessus_ATCC_1997 GRRLGSANLALEAVAADSHSAATLQVPDSAPLLLLERLTHLDDGTPVDLE
Mb0816c|M.bovis_AF2122/97 GVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVV
Rv0792c|M.tuberculosis_H37Rv GVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVV
MMAR_2560|M.marinum_M GVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPLEVV
MUL_3201|M.ulcerans_Agy99 GVRISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPLEVV
Mflv_1234|M.gilvum_PYR-GCK GLVTARADERIEAVNATPEEANLLGIKPRSALLLITRIAYDQHDTPCEFS
Mvan_5574|M.vanbaalenii_PYR-1 GLVTARADERIEAVNATPEEANLLGIKAKSALLLITRITYDQHDTPCEFS
TH_3932|M.thermoresistible__bu GVRMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHGAPVAVV
* * . :. * * * : :.:* : . * .
MAV_5032|M.avium_104 TVRYRGDRCSLVTTATR-EDAPPQ-------------------
MSMEG_1227|M.smegmatis_MC2_155 TVRYRGDRCTLMTTAARGVDDPPQAPQEPPQ------------
MAB_2239|M.abscessus_ATCC_1997 YIRMRGDRITLRSNLLRDI------------------------
Mb0816c|M.bovis_AF2122/97 VFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA----------
Rv0792c|M.tuberculosis_H37Rv VFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA----------
MMAR_2560|M.marinum_M LFHHRPERYEFCVTLPRTMPGQRAGMTER--------------
MUL_3201|M.ulcerans_Agy99 LFHHRPERYEFCVTLPRTMPGQRAGMTER--------------
Mflv_1234|M.gilvum_PYR-GCK RDLFRGDRTRLAVTAQGRGVGASPSVAAASVALHGPLAKAPSA
Mvan_5574|M.vanbaalenii_PYR-1 RDLFRGDRTRLAVTAQGRGVGVQPSVAAASVALQSPPI-----
TH_3932|M.thermoresistible__bu RHRFRGDRVELTVDLA---------------------------
* :* :