For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VARTRRAGAALPYGALDRDHLVKHLLELARRVGVENVTMRALATEAGTSASSVYYHVKDKAALLDLLAES VIESIEVPTEGDWEQRTRALYTNAWKVMIAIPGIAAMLQQRPLTGAADAVDRTVKAIMAESGWTADEVAA AHVVLYIHLLGSVQLEHHLRHSGIEIKSDDGAESVFQHGLRVILAGLRSCHTETSTPTT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5480 | - | - | 100% (199) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1989 | - | 2e-08 | 22.22% (153) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3167 | - | 8e-06 | 32.23% (121) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 4e-07 | 20.67% (179) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1322 | - | 5e-71 | 77.25% (167) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 4e-07 | 20.67% (179) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4320c | - | 1e-09 | 28.39% (155) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 1e-09 | 28.36% (134) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 2e-07 | 24.48% (143) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2583 | - | 6e-10 | 24.49% (196) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_1116 | - | 1e-07 | 23.57% (157) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_3622 | - | 1e-09 | 28.36% (134) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5480|M.vanbaalenii_PYR-1 -------------MARTRRAGAALPYGALDRDHLVKHLLELARRVGVENV
Mflv_1322|M.gilvum_PYR-GCK ----------------------------------MKHLLELARRVGVDHV
MMAR_3679|M.marinum_M --------MFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MUL_3622|M.ulcerans_Agy99 MISIRTSYVFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MSMEG_2583|M.smegmatis_MC2_155 ----------------------MPRQRSLTRPQIAAAALEVVDTDGLGSL
Mb1388c|M.bovis_AF2122/97 -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
Rv1353c|M.tuberculosis_H37Rv -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
TH_1116|M.thermoresistible__bu -----------VAKQATADKRRRRERGSINPDDIVAGAFELAEEVGIDNL
MAB_4320c|M.abscessus_ATCC_199 ------MQRDRESDDTARRGRGRPSVGVLNRDRIVDAALAELRASGLRKL
MAV_5055|M.avium_104 -----------------------MRRAGLKREAVVRAAVKIADAEGIEAI
. .: :
Mvan_5480|M.vanbaalenii_PYR-1 TMRALATEAGTSASSVYYHVKDKAALLDLLAESVIESIEVPT----EGDW
Mflv_1322|M.gilvum_PYR-GCK TMRGLAAEAGTSASSVYYHVKDKAALMDLLAESVIESIEVPA----DGDW
MMAR_3679|M.marinum_M SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAP---TDDW
MUL_3622|M.ulcerans_Agy99 SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAP---IDDW
MSMEG_2583|M.smegmatis_MC2_155 SMRTVARRLGMGTMSLYRYVADRDELEAMVVELVLESVDLRPP---AGSA
Mb1388c|M.bovis_AF2122/97 SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
Rv1353c|M.tuberculosis_H37Rv SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
TH_1116|M.thermoresistible__bu SMPLLGKHLGVGVTSIYWYFRKKDDLLNEMTNRALRQYVFETPYVEAGNW
MAB_4320c|M.abscessus_ATCC_199 TMRAVAVRLGVTVAALYNHVPSRAGLLVAVQERFTAGLDVSGFG--VVPL
MAV_5055|M.avium_104 SMRRVSQALGVTPMALYRYLPDKDALIDVVVDESLAVVPVPDP---SGSV
:* :. * ::* :. .: * : : .
Mvan_5480|M.vanbaalenii_PYR-1 EQRTRALYTNAWKVMIAIP-GIAAMLQQRPLTGAADAVD----RTVKAIM
Mflv_1322|M.gilvum_PYR-GCK RRRISALYTNAWTVMYDIP-GVAAMLQQRPLAGAAHAMD----RTARAIM
MMAR_3679|M.marinum_M RADVHAIATAMWETMRQHPNAIPLVLTRRTVSASSYMVA----DRLIAAL
MUL_3622|M.ulcerans_Agy99 RADVHAIATAMWETMRQHPNAIPLVLTRRTVWASSYMVA----DRLIAAL
MSMEG_2583|M.smegmatis_MC2_155 RHRILVLAERVRDATARHPAVVPLLLAHRHRLPASLRWG----EAVLGVL
Mb1388c|M.bovis_AF2122/97 RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
Rv1353c|M.tuberculosis_H37Rv RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
TH_1116|M.thermoresistible__bu RESLRNHARNMRKTFLSSPILTDLVLIRGALNTKIRKLGLQQMEAAIDSL
MAB_4320c|M.abscessus_ATCC_199 REALSRWAWSYLDQLRRRPELVPLIVEVP-LAQAPLTSG--MYQRVTAGF
MAV_5055|M.avium_104 TAELLRCFGGLYDLLLDHPGLARAAGERPLEGPFATRLG----NNVLTLL
* :
Mvan_5480|M.vanbaalenii_PYR-1 AESGWTADEVAAAHVVLYIHLLGSVQLEHHLRHSGIE-------------
Mflv_1322|M.gilvum_PYR-GCK AEAGWDGEQISRAHAVLYIHLLGSIQLAHHLRDSGID-------------
MMAR_3679|M.marinum_M GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
MUL_3622|M.ulcerans_Agy99 GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
MSMEG_2583|M.smegmatis_MC2_155 AEAGYAGKRRVYAFRALLACTFGALEIQHHSALSGPG--------TRALA
Mb1388c|M.bovis_AF2122/97 VTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAI
Rv1353c|M.tuberculosis_H37Rv VTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAI
TH_1116|M.thermoresistible__bu VQAGLSPEDAFDTYSAVSVHVRGSVVLERLHEKTQDLFNGG---DEPSAV
MAB_4320c|M.abscessus_ATCC_199 AAAGWPEESIIASMSILETFIFGAAVDSPGPTDVYAP-------YDPANA
MAV_5055|M.avium_104 QHNKIDEADAANLLVSAFSLTLGCALYRTSRSGRTAS---------SRLS
*.
Mvan_5480|M.vanbaalenii_PYR-1 ---------------IKSDDGAESVFQHGLRVILAGLRSCHTETSTPTT-
Mflv_1322|M.gilvum_PYR-GCK ---------------GGSDDGAHSVFQHGLRVILTGLQ--HTSPLP----
MMAR_3679|M.marinum_M GLAGAEHPHIAALAQASQRSTPAADFERALDILLAGIESFERRRDRR---
MUL_3622|M.ulcerans_Agy99 GLAGAEHPHIAALAQASQRSTPAADFERALDILLAGIESFERRRDRR---
MSMEG_2583|M.smegmatis_MC2_155 ELPADEFPRLSETAAAARGIGAGDEFRHGLEILLRGLQI-----------
Mb1388c|M.bovis_AF2122/97 DPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGE
Rv1353c|M.tuberculosis_H37Rv DPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGE
TH_1116|M.thermoresistible__bu DPASTPIIAELLAKGHRLAEADERNFEYTLECILDHAERLIEER--AAG-
MAB_4320c|M.abscessus_ATCC_199 PQMGRVYEAFARSVRERQTRAHDLVFTMGLDAALIGLHHIWGTGRGWAGV
MAV_5055|M.avium_104 QVGDEAPAVRRLRGRLTVASADDTVFRDALTRLIAGYVTTAAKTGGRRR-
* * :
Mvan_5480|M.vanbaalenii_PYR-1 ------------------------
Mflv_1322|M.gilvum_PYR-GCK ------------------------
MMAR_3679|M.marinum_M ------------------------
MUL_3622|M.ulcerans_Agy99 ------------------------
MSMEG_2583|M.smegmatis_MC2_155 ------------------------
Mb1388c|M.bovis_AF2122/97 VAVRRPTATADAPTPGARAKAVAR
Rv1353c|M.tuberculosis_H37Rv VAVRRPTATADAPTPGARAKAVAR
TH_1116|M.thermoresistible__bu ---------------GTRK-----
MAB_4320c|M.abscessus_ATCC_199 RLPVQRQ-----------------
MAV_5055|M.avium_104 ------------------------