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QRDRESDDTARRGRGRPSVGVLNRDRIVDAALAELRASGLRKLTMRAVAVRLGVTVAALYNHVPSRAGLL VAVQERFTAGLDVSGFGVVPLREALSRWAWSYLDQLRRRPELVPLIVEVPLAQAPLTSGMYQRVTAGFAA AGWPEESIIASMSILETFIFGAAVDSPGPTDVYAPYDPANAPQMGRVYEAFARSVRERQTRAHDLVFTMG LDAALIGLHHIWGTGRGWAGVRLPVQRQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4320c | - | - | 100% (239) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4687 | - | 3e-07 | 33.64% (110) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3852c | - | 2e-06 | 46.55% (58) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 4e-05 | 40.68% (59) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_4581 | - | 3e-08 | 36.00% (100) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 4e-05 | 40.68% (59) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2639 | - | 3e-08 | 32.19% (146) | hypothetical protein MMAR_2639 |
| M. avium 104 | MAV_2958 | - | 2e-09 | 34.27% (143) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0442 | - | 3e-12 | 25.85% (205) | tetracycline repressor domain-containing protein |
| M. thermoresistible (build 8) | TH_1893 | - | 4e-06 | 27.85% (158) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_3114 | - | 9e-07 | 33.60% (125) | hypothetical protein MUL_3114 |
| M. vanbaalenii PYR-1 | Mvan_5480 | - | 2e-09 | 28.39% (155) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3605|M.bovis_AF2122/97 -----------------------MAVLAESELG----SEAQRERRKRILD
Rv3574|M.tuberculosis_H37Rv -----------------------MAVLAESELG----SEAQRERRKRILD
Mflv_4581|M.gilvum_PYR-GCK ------MTFPQARSHGKTLPSEANSVATEKRAANASRSRASARRRETILD
MMAR_2639|M.marinum_M MTLSGEPGYSYTGLVSSDNADPPDAGTGAPVPAGRRSDRRPAQTIRKVLE
MUL_3114|M.ulcerans_Agy99 --------------------------------------------------
MAV_2958|M.avium_104 ---------------MPEDASSPVIAGGAPTGPARRSDRRPGQTIRKVLD
MAB_4320c|M.abscessus_ATCC_199 --------------------MQRDRESDDTARRGRGRPSVGVLNRDRIVD
MSMEG_0442|M.smegmatis_MC2_155 ----------------------------------MGRPSTPILSTDRIAT
Mvan_5480|M.vanbaalenii_PYR-1 ---------------------------MARTRRAGAALPYGALDRDHLVK
TH_1893|M.thermoresistible__bu -----------------VNTQMSAGPGGAPGARTKSPARAGRLSRDTIVN
Mb3605|M.bovis_AF2122/97 ATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFS
Rv3574|M.tuberculosis_H37Rv ATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFS
Mflv_4581|M.gilvum_PYR-GCK AALTVAAAGGYEAVQMRTVAERVGIAVGTLYRYFPAKTHLLVAALTREFR
MMAR_2639|M.marinum_M AGLDELRATSFANLTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLLR
MUL_3114|M.ulcerans_Agy99 --MDELRATSFANLTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLLR
MAV_2958|M.avium_104 AGLQELRESSYAGLTMRAVATRAGVSPASAYTYFPSKSALVAAVYLRFLR
MAB_4320c|M.abscessus_ATCC_199 AALAELRASGLRKLTMRAVAVRLGVTVAALYNHVPSRAGLLVAVQERFTA
MSMEG_0442|M.smegmatis_MC2_155 AALDLVNSTG--GFTIPGLARRLKVSPSSLYNHVAGREQIVELLRERAMS
Mvan_5480|M.vanbaalenii_PYR-1 HLLELARRVGVENVTMRALATEAGTSASSVYYHVKDKAALLDLLAESVIE
TH_1893|M.thermoresistible__bu AALTFLDREGWDALTINALATQLGTKGPSLYNHVQSLDDLRRSVRMRVVD
: . . : :* . : * :. :
Mb3605|M.bovis_AF2122/97 RIDAK-----------TDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLT-
Rv3574|M.tuberculosis_H37Rv RIDAK-----------TDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLT-
Mflv_4581|M.gilvum_PYR-GCK RLDSA-----------GDWASGEGP-PLERLERLTAHLHDRWQRDPRLT-
MMAR_2639|M.marinum_M DLPLH-----------TDVN----DTTKTRVSATMRDMAMVVADEPELT-
MUL_3114|M.ulcerans_Agy99 DLPLH-----------TDVN----DTTKTRVSATMRDMAMVVADEPELT-
MAV_2958|M.avium_104 DLPVH-----------TDVN----ETAQRRVSATLRDMAVVVADEPELT-
MAB_4320c|M.abscessus_ATCC_199 GLDVSGFGVVPLREALSRWAWSYLDQLRRRPELVPLIVEVPLAQAPLTSG
MSMEG_0442|M.smegmatis_MC2_155 EVNLPDLDTDRPWSDVVADIMRSYRRSFARYPRLIPLLTIHAVNSTQAFR
Mvan_5480|M.vanbaalenii_PYR-1 SIEVPTEG-------DWEQRTRALYTNAWKVMIAIPGIAAMLQQRPLTGA
TH_1893|M.thermoresistible__bu DIIGMLNAAGQGR--TRDDAVLAMASAYRSYAHHHPGRYSAFTRMPLGGD
: .
Mb3605|M.bovis_AF2122/97 -----EAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHI
Rv3574|M.tuberculosis_H37Rv -----EAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHI
Mflv_4581|M.gilvum_PYR-GCK -----TAMTRAFAVADTRAAAELDRAADEIQILLARTLRGGEPTPTDLHV
MMAR_2639|M.marinum_M -----AACGTALMADDPAVQPLRAQIGEEVARRIGAALGPGWPRSVKSTL
MUL_3114|M.ulcerans_Agy99 -----AACGTALMADDPAVQPLRTQIGEEVARRIGAALGPGWPRSVKSTL
MAV_2958|M.avium_104 -----AACGAALMADDPAVKPLREQIGEEVSRRIAAALGPGWPRAVKSTL
MAB_4320c|M.abscessus_ATCC_199 M---YQRVTAGFAAAGWPEESIIASMSILETFIFGAAVDSPGPTDVYAPY
MSMEG_0442|M.smegmatis_MC2_155 M---YNALAVTLGRAGFSAADSLRIITLIDNYVLGSALDLAAPDEPWESG
Mvan_5480|M.vanbaalenii_PYR-1 ADAVDRTVKAIMAESGWTADEVAAAHVVLYIHLLGSVQLEHHLRHSGIEI
TH_1893|M.thermoresistible__bu D----PEFSAAARAAAGPVIAVLGSYGLEGEEAFYAALEFWSALHGFVLL
: .
Mb3605|M.bovis_AF2122/97 ARV----ISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA---
Rv3574|M.tuberculosis_H37Rv ARV----ISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA---
Mflv_4581|M.gilvum_PYR-GCK AGV----ISDIWLANLVAFSGHRATAADTRERIDRATRRVVTSAARPTAN
MMAR_2639|M.marinum_M QMT----FSGALMT------ARFLSYEEIAGQLDEAVNLILGAAVA----
MUL_3114|M.ulcerans_Agy99 QMT----FSGALMT------ARFLSYEEIAGQLDEAVNLILGAAVA----
MAV_2958|M.avium_104 QMT----FSGALMT------ARFVSFAEISGQLDEAVDLILGAARAS---
MAB_4320c|M.abscessus_ATCC_199 DPANAPQMGRVYEAFARSVRERQTRAHDLVFTMGLDAALIGLHHIWGTGR
MSMEG_0442|M.smegmatis_MC2_155 TEVG-PELAAALATG-----APKPARADDAFEFGLAVLLRGLTNP-----
Mvan_5480|M.vanbaalenii_PYR-1 KSD---------------------DGAESVFQHGLRVILAGLRSCHTETS
TH_1893|M.thermoresistible__bu EMTG----------------VMDDVDSDKVFTDMVLRLAAGMEKRS----
:
Mb3605|M.bovis_AF2122/97 ------------
Rv3574|M.tuberculosis_H37Rv ------------
Mflv_4581|M.gilvum_PYR-GCK R-----------
MMAR_2639|M.marinum_M ------------
MUL_3114|M.ulcerans_Agy99 ------------
MAV_2958|M.avium_104 ------------
MAB_4320c|M.abscessus_ATCC_199 GWAGVRLPVQRQ
MSMEG_0442|M.smegmatis_MC2_155 ------------
Mvan_5480|M.vanbaalenii_PYR-1 TPTT--------
TH_1893|M.thermoresistible__bu ------------