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ISIRTSYVFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVR DRRELEALVADAVVADVKVPAPIDDWRADVHAIATAMWETMRQHPNAIPLVLTRRTVWASSYMVADRLIA ALGRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIGGLAGAEHPHIAALAQASQ RSTPAADFERALDILLAGIESFERRRDRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3622 | - | - | 100% (240) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_3884 | - | 3e-07 | 26.17% (149) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 6e-06 | 25.50% (149) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2560 | - | 2e-14 | 29.17% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 6e-06 | 25.50% (149) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4687 | - | 1e-13 | 26.42% (212) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 1e-125 | 99.14% (232) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 6e-10 | 25.87% (143) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2583 | - | 3e-23 | 31.19% (202) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_0654 | - | 5e-10 | 25.87% (201) | transcriptional regulator, TetR family protein |
| M. vanbaalenii PYR-1 | Mvan_4078 | - | 5e-16 | 29.73% (222) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3622|M.ulcerans_Agy99 ----------------MISIRTSYVFTLRTMYLSTVWEGDVR------AR
MMAR_3679|M.marinum_M ------------------------MFTLRTMYLSTVWEGDVR------AR
MSMEG_2583|M.smegmatis_MC2_155 --------------------------------------MPRQ------RS
Mflv_2560|M.gilvum_PYR-GCK MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQR
Mvan_4078|M.vanbaalenii_PYR-1 -----------MVTRGAGPERSSAGDPVRTLKLLWRTPGEARTSRGPRQR
Mb1388c|M.bovis_AF2122/97 ---------------------------------MQTTPGKRQ--RRQRGS
Rv1353c|M.tuberculosis_H37Rv ---------------------------------MQTTPGKRQ--RRQRGS
MAB_4687|M.abscessus_ATCC_1997 --------------------------------MTDERRMRGR------PP
TH_0654|M.thermoresistible__bu ------------------------------------------------VQ
MAV_5055|M.avium_104 ---------------------------------------MRR------AG
MUL_3622|M.ulcerans_Agy99 FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MMAR_3679|M.marinum_M FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MSMEG_2583|M.smegmatis_MC2_155 LTRPQIAAAALEVVDTDGLGSLSMRTVARRLGMGTMSLYRYVADRDELEA
Mflv_2560|M.gilvum_PYR-GCK TSVDAVVAAAVGIADTQGLSAVTIRAVAGVLGLAPMAIYTYVPGKAELLD
Mvan_4078|M.vanbaalenii_PYR-1 TTVDAVVAAAIEIADADGLGAVTIRAVATRLGIATMATYTYVPGKAELLD
Mb1388c|M.bovis_AF2122/97 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
Rv1353c|M.tuberculosis_H37Rv INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
MAB_4687|M.abscessus_ATCC_1997 LPMETIVDAALQIVDEEGGEALSMRALARRLDSGTATIYRHFANRTEVVA
TH_0654|M.thermoresistible__bu LRKSDVVDAATAILDNYGIADLTTRRLARELGVTAGALYWHFANKQELLG
MAV_5055|M.avium_104 LKREAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPDKDALID
: .* : : . :: :. *. : * :. : :
MUL_3622|M.ulcerans_Agy99 LVADAVVADVKVPAPIDD---WRADVHAIATAMWETMRQHPNAIPLVLTR
MMAR_3679|M.marinum_M LVADAVVADVKVPAPTDD---WRADVHAIATAMWETMRQHPNAIPLVLTR
MSMEG_2583|M.smegmatis_MC2_155 MVVELVLESVDLRPPAGS---ARHRILVLAERVRDATARHPAVVPLLLAH
Mflv_2560|M.gilvum_PYR-GCK LMLDSVYGQMSRGDLSGLP--WRHRVTAIADENRALLDEHPWVTQLATTR
Mvan_4078|M.vanbaalenii_PYR-1 LMLDTVYRQMPRRDLSGMA--WRDRVSAIAGENRELLEQHPWVAQLATTR
Mb1388c|M.bovis_AF2122/97 AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
Rv1353c|M.tuberculosis_H37Rv AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
MAB_4687|M.abscessus_ATCC_1997 HVVDRVFGEVQLDDPALARMPWQDACIVSSRALFDALRRHPNVAMLLADQ
TH_0654|M.thermoresistible__bu AVADRILTPVPAGEPEPG---WAERISSTAGRLRDALLSHTDGAELVSAT
MAV_5055|M.avium_104 VVVDESLAVVPVPDPSGS---VTAELLRCFGGLYDLLLDHPGLARAAGER
: : :.
MUL_3622|M.ulcerans_Agy99 RTVWASSYMVADRLIA-ALGRSGVGDADLLASFRGVLGLVMGSAQAELAG
MMAR_3679|M.marinum_M RTVSASSYMVADRLIA-ALGRSGVGDADLLASFRGVLGLVMGSAQAELAG
MSMEG_2583|M.smegmatis_MC2_155 RHRLPASLRWGEAVLG-VLAEAGYAGKRRVYAFRALLACTFGALEIQHHS
Mflv_2560|M.gilvum_PYR-GCK PPLGPGTAAKYDHELR-AFDGLGLSDLDMDSALTYVLGFVTSVARIADDA
Mvan_4078|M.vanbaalenii_PYR-1 PPLGPGMIAKYEHELC-AFDGLGLSDLDMDSALTYVLGFVMSVARIAIDT
Mb1388c|M.bovis_AF2122/97 AALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLD
Rv1353c|M.tuberculosis_H37Rv AALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLD
MAB_4687|M.abscessus_ATCC_1997 IPVGPNVFMIREHTLTLCLQAG----FSPAEAIRIYMTLGRYVLGFANQI
TH_0654|M.thermoresistible__bu FAAGQS--RVLDEILARFAAAAAAAGLEGSRAVLAARTIVHYVLGFTGDE
MAV_5055|M.avium_104 PLEGPFATRLGNNVLT-LLQHNKIDEADAANLLVSAFSLTLGCALYRTSR
: .
MUL_3622|M.ulcerans_Agy99 PLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQAS-----QRST
MMAR_3679|M.marinum_M PLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQAS-----QRST
MSMEG_2583|M.smegmatis_MC2_155 ALSGPG--------TRALA-----ELPADEFPRLSETAAAA-----RGIG
Mflv_2560|M.gilvum_PYR-GCK REARRDSGVSDQAWWDRAGPLLAEVFDDEKFPLAARIGAAAGQAFGSAYD
Mvan_4078|M.vanbaalenii_PYR-1 NAARADSGVTDDTWWEQAGPVLATVFDADEFPLAARVGEAAGRALGGAYN
Mb1388c|M.bovis_AF2122/97 RLSRKSQSAGSGPSAIEHP----VAIDPATTPLLAHATGRG---HRIGAP
Rv1353c|M.tuberculosis_H37Rv RLSRKSQSAGSGPSAIEHP----VAIDPATTPLLAHATGRG---HRIGAP
MAB_4687|M.abscessus_ATCC_1997 GAEHRASEADIAMLTRLVEN-----IDLASYPSTLATAGVT------LVP
TH_0654|M.thermoresistible__bu QS----------------------RLQWDAAGAEVAEPPAD-------DN
MAV_5055|M.avium_104 SGRTASSRLS---------------QVGDEAPAVRRLRGRLT----VASA
MUL_3622|M.ulcerans_Agy99 PAADFERALDILLAGIESFERRRDRR------------------------
MMAR_3679|M.marinum_M PAADFERALDILLAGIESFERRRDRR------------------------
MSMEG_2583|M.smegmatis_MC2_155 AGDEFRHGLEILLRGLQI--------------------------------
Mflv_2560|M.gilvum_PYR-GCK ADHAYRFGLARVLDGLEPVINRTAR-------------------------
Mvan_4078|M.vanbaalenii_PYR-1 AEHAYRFGLARVLDGLAPVIGDRARGSGRSPAN-----------------
Mb1388c|M.bovis_AF2122/97 DETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKA
Rv1353c|M.tuberculosis_H37Rv DETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKA
MAB_4687|M.abscessus_ATCC_1997 LDEEFDFGLGLIVAGLEGLRHGE---------------------------
TH_0654|M.thermoresistible__bu PSARFAFGLNLLINGIAAEIDAAARKSE----------------------
MAV_5055|M.avium_104 DDTVFRDALTRLIAGYVTTAAKTGGRRR----------------------
: .* ::
MUL_3622|M.ulcerans_Agy99 ---
MMAR_3679|M.marinum_M ---
MSMEG_2583|M.smegmatis_MC2_155 ---
Mflv_2560|M.gilvum_PYR-GCK ---
Mvan_4078|M.vanbaalenii_PYR-1 ---
Mb1388c|M.bovis_AF2122/97 VAR
Rv1353c|M.tuberculosis_H37Rv VAR
MAB_4687|M.abscessus_ATCC_1997 ---
TH_0654|M.thermoresistible__bu ---
MAV_5055|M.avium_104 ---