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RRAGLKREAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPDKDALIDVVVDESLAVVPVPDPS GSVTAELLRCFGGLYDLLLDHPGLARAAGERPLEGPFATRLGNNVLTLLQHNKIDEADAANLLVSAFSLT LGCALYRTSRSGRTASSRLSQVGDEAPAVRRLRGRLTVASADDTVFRDALTRLIAGYVTTAAKTGGRRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5055 | - | - | 100% (210) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5169 | - | 2e-05 | 33.33% (54) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5267 | - | 6e-05 | 27.08% (96) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2560 | - | 6e-12 | 38.00% (100) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2957c | - | 2e-10 | 30.43% (184) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 2e-10 | 25.87% (143) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3332 | - | 3e-13 | 31.97% (147) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0654 | - | 8e-09 | 36.78% (87) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3622 | - | 4e-10 | 25.87% (143) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4078 | - | 2e-13 | 39.00% (100) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3679|M.marinum_M ------------------------MFTLRTMYLSTVWEGDVR------AR
MUL_3622|M.ulcerans_Agy99 ----------------MISIRTSYVFTLRTMYLSTVWEGDVR------AR
Mflv_2560|M.gilvum_PYR-GCK MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQR
Mvan_4078|M.vanbaalenii_PYR-1 -----------MVTRGAGPERSSAGDPVRTLKLLWRTPGEARTSRGPRQR
TH_0654|M.thermoresistible__bu ------------------------------------------------VQ
MSMEG_3332|M.smegmatis_MC2_155 ----------------------MTQPPAGPSGPGDSAPSADATENGQNRP
MAV_5055|M.avium_104 ---------------------------------------------MRRAG
MAB_2957c|M.abscessus_ATCC_199 ---------------------------------------------MTDPR
MMAR_3679|M.marinum_M FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MUL_3622|M.ulcerans_Agy99 FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
Mflv_2560|M.gilvum_PYR-GCK TSVDAVVAAAVGIADTQGLSAVTIRAVAGVLGLAPMAIYTYVPGKAELLD
Mvan_4078|M.vanbaalenii_PYR-1 TTVDAVVAAAIEIADADGLGAVTIRAVATRLGIATMATYTYVPGKAELLD
TH_0654|M.thermoresistible__bu LRKSDVVDAATAILDNYGIADLTTRRLARELGVTAGALYWHFANKQELLG
MSMEG_3332|M.smegmatis_MC2_155 ITREAVLAGALDIIDRDGVDALSMRRLGEALGRDPMALYRHVPNKAAVLD
MAV_5055|M.avium_104 LKREAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPDKDALID
MAB_2957c|M.abscessus_ATCC_199 LTLESIVGKAIEIADSDGLSGVSMRKIADALGVGAMSLYRHVADKDALLV
. : * * * *: :: * :. ** . : * :. .: :
MMAR_3679|M.marinum_M LVADAVVADVKVP---APTDDWRADVHAIATAMWETMRQHPNAIPLVLTR
MUL_3622|M.ulcerans_Agy99 LVADAVVADVKVP---APIDDWRADVHAIATAMWETMRQHPNAIPLVLTR
Mflv_2560|M.gilvum_PYR-GCK LMLDSVYGQMSRGD--LSGLPWRHRVTAIADENRALLDEHPWVTQLATTR
Mvan_4078|M.vanbaalenii_PYR-1 LMLDTVYRQMPRRD--LSGMAWRDRVSAIAGENRELLEQHPWVAQLATTR
TH_0654|M.thermoresistible__bu AVADRILTPVPAG---EPEPGWAERISSTAGRLRDALLSHTDGAELVS--
MSMEG_3332|M.smegmatis_MC2_155 GVVEMIFEQLSLD---TTTPDWIAALRRLGHDFRNLARAHPNVVPLLVTR
MAV_5055|M.avium_104 VVVDESLAVVPVP---DPSGSVTAELLRCFGGLYDLLLDHPGLARAAGER
MAB_2957c|M.abscessus_ATCC_199 EMTAEVTRRFAYPDEMMGVPDWRARVRVAVEHDFDLYSTHPWVLLAYAVP
: . : *.
MMAR_3679|M.marinum_M RTVSAS------SYMVADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQ
MUL_3622|M.ulcerans_Agy99 RTVWAS------SYMVADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQ
Mflv_2560|M.gilvum_PYR-GCK PPLGPG------TAAKYDHELRAFDGLGLSDLDMDSALTYVLGFVTSVAR
Mvan_4078|M.vanbaalenii_PYR-1 PPLGPG------MIAKYEHELCAFDGLGLSDLDMDSALTYVLGFVMSVAR
TH_0654|M.thermoresistible__bu ATFAAG------QSRVLDEILARFAAA--------AAAAGLEGSRAVLAA
MSMEG_3332|M.smegmatis_MC2_155 PLATPLGMRPPGILRHLEQILALLTRCGFTGPDALHVYRTLFGFLYGHVL
MAV_5055|M.avium_104 PLEGPF------ATRLGNNVLTLLQHNKIDEADAANLLVSAFSLTLGCAL
MAB_2957c|M.abscessus_ATCC_199 RNGMQP-----ETLVCFDWLLEAFSHLGVAAPEAAELTFQVWSYSQGVGL
: : : .
MMAR_3679|M.marinum_M AELAGPLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQASQRST
MUL_3622|M.ulcerans_Agy99 AELAGPLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQASQRST
Mflv_2560|M.gilvum_PYR-GCK IADDAREARRDSGVSDQAWWDRAGPLLAEVFDDEKFPLAARIGAAAGQAF
Mvan_4078|M.vanbaalenii_PYR-1 IAIDTNAARADSGVTDDTWWEQAGPVLATVFDADEFPLAARVGEAAGRAL
TH_0654|M.thermoresistible__bu RTIVHYVLGFTGDEQSRLQWDAAG---------------AEVAEPPADDN
MSMEG_3332|M.smegmatis_MC2_155 TELQEIVERPE-ETDHVMRLGLHR------LPIGEFPHVRDLAPTWAAYD
MAV_5055|M.avium_104 YRTSR------SGRTASSRLSQVG---------DEAPAVRRLRGRLTVAS
MAB_2957c|M.abscessus_ATCC_199 GAVGGQLVSPGARTDFSGLSELIAG-------NAEVPESPRLAALLGLGD
:
MMAR_3679|M.marinum_M -----PAADFERALDILLAGIESFERRRDRR--------
MUL_3622|M.ulcerans_Agy99 -----PAADFERALDILLAGIESFERRRDRR--------
Mflv_2560|M.gilvum_PYR-GCK GSAYDADHAYRFGLARVLDGLEPVINRTAR---------
Mvan_4078|M.vanbaalenii_PYR-1 GGAYNAEHAYRFGLARVLDGLAPVIGDRARGSGRSPAN-
TH_0654|M.thermoresistible__bu -----PSARFAFGLNLLINGIAAEIDAAARKSE------
MSMEG_3332|M.smegmatis_MC2_155 G-----LAELDRGLDILLTGLATRLDMPGGMPTRAPEPG
MAV_5055|M.avium_104 ----ADDTVFRDALTRLIAGYVTTAAKTGGRRR------
MAB_2957c|M.abscessus_ATCC_199 ------LPEVTNPREVIAKGVEILCDGIARRYHKL----
: *