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M. thermoresistible (build 8) TH_1116 ()

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
coordinates: 2176086 - 2176799
length: 238

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1116-100% (238)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. thermoresistible (build 8)TH_0654-4e-0629.90% (97) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1388c-5e-8968.09% (235) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_4355-9e-9169.17% (240) TetR family transcriptional regulator
M. tuberculosis H37RvRv1353c-5e-8968.09% (235) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1508c-6e-5545.37% (227) putative HTH-type transcriptional regulator
M. marinum MMMAR_4019-5e-9470.94% (234) transcriptional regulatory protein
M. avium 104MAV_1586-3e-9371.98% (232) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_2225-3e-9067.92% (240) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_3884-4e-9470.94% (234) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_1989-3e-9371.37% (234) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4019|M.marinum_M               ---MEVPVVAKRAAAD------KRQRRERGSINPDDIISGAFELAEQVSI
MUL_3884|M.ulcerans_Agy99           ---MEVPVVAKRAAAD------KRQRRERGSINPDDIISGAFELAEQVSI
MAV_1586|M.avium_104                --------MAKQATAD------KRQRRERGSINPDDIITGAFELAEQVSI
Mb1388c|M.bovis_AF2122/97           ----------MQTTPG------KRQRRQRGSINPEDIISGAFELAQQVSI
Rv1353c|M.tuberculosis_H37Rv        ----------MQTTPG------KRQRRQRGSINPEDIISGAFELAQQVSI
Mflv_4355|M.gilvum_PYR-GCK          --------MARQATAE------KRQRRERGSINPDDIIKGAFELAEQVGI
Mvan_1989|M.vanbaalenii_PYR-1       --------MAKQATAE------KRQRRERGSINPDDIIKGAFELAEQVGI
MSMEG_2225|M.smegmatis_MC2_155      --------MAKQPAAE------KRQRRERGSINPEDIIKGAFELAEKVSI
TH_1116|M.thermoresistible__bu      --------VAKQATAD------KRRRRERGSINPDDIVAGAFELAEEVGI
MAB_1508c|M.abscessus_ATCC_199      MRHAGVGHEARTTSTQGPSHSPKRERRRRGSITAEDIIAGAFELAEEIGI
                                                .:.       **.**.****..:**: ******:::.*

MMAR_4019|M.marinum_M               DNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEA
MUL_3884|M.ulcerans_Agy99           DNLSMPMLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEG
MAV_1586|M.avium_104                DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYVEA
Mb1388c|M.bovis_AF2122/97           DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEA
Rv1353c|M.tuberculosis_H37Rv        DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEA
Mflv_4355|M.gilvum_PYR-GCK          DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALRQYAFATPYVEA
Mvan_1989|M.vanbaalenii_PYR-1       DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALRQYAFATPYVEA
MSMEG_2225|M.smegmatis_MC2_155      DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALREFVVATPYVEA
TH_1116|M.thermoresistible__bu      DNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNEMTNRALRQYVFETPYVEA
MAB_1508c|M.abscessus_ATCC_199      SGLSMPLLAKHLDVGVTSIYWYFRKKGELLDAMTDRATKQYHFAAPFVGD
                                    ..****:*.***.*************.:**: **:**  :: . :*::  

MMAR_4019|M.marinum_M               SDWRETLRNHARLMRKTFMGNPILCDLILIR-SALSPKAARLGAQEMERA
MUL_3884|M.ulcerans_Agy99           SDWRETLRNHARLMRKTFMSNPILCDLILIR-SALSPKTARLGAQKMERA
MAV_1586|M.avium_104                SDWRETLRNHARLMRKTFMGNPILCDLILIR-AALSPKAARLGAQEMEKA
Mb1388c|M.bovis_AF2122/97           GDWRETLRNHARSMRKTFADNPVLCDLILIR-AALSPKTARLGAQEMEKA
Rv1353c|M.tuberculosis_H37Rv        GDWRETLRNHARSMRKTFADNPVLCDLILIR-AALSPKTARLGAQEMEKA
Mflv_4355|M.gilvum_PYR-GCK          RDWRETLANHARTMRKTFNGNPILCDLILIR-SALSPRAAKVGVQQVEKA
Mvan_1989|M.vanbaalenii_PYR-1       KDWRETLANHARSMRQTFNGNPILCDLILIR-SALSPRAAKLGVQEVERA
MSMEG_2225|M.smegmatis_MC2_155      KDWRESLANHARTMRKAFMGNPILCDLILIR-SALSPRAARVGVQEVESA
TH_1116|M.thermoresistible__bu      GNWRESLRNHARNMRKTFLSSPILTDLVLIR-GALNTKIRKLGLQQMEAA
MAB_1508c|M.abscessus_ATCC_199      ETWQDALRSHTHRMREAFRERPVLVELILMRTSELSSEALQASIQNLESL
                                      *:::* .*:: **::*   *:* :*:*:* . *...  : . *::*  

MMAR_4019|M.marinum_M               IANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIED
MUL_3884|M.ulcerans_Agy99           IANLVEAGLSPEDAFDTYAAVSIHVRGSVVLHRLYEKTQSADSGPRAIED
MAV_1586|M.avium_104                VANLVQAGLSPEDAFDTYSAISVHVRGSVVLQRLYEKNQSSDVGPRAIED
Mb1388c|M.bovis_AF2122/97           IANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEH
Rv1353c|M.tuberculosis_H37Rv        IANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEH
Mflv_4355|M.gilvum_PYR-GCK          IGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGDDGHGDIDD
Mvan_1989|M.vanbaalenii_PYR-1       IGSLVEAGLSPEDAFDTYSAMSVHVRGSVVLQRLREKNLAGEDGHGDIDD
MSMEG_2225|M.smegmatis_MC2_155      IAGLVEAGLSVEDAFDTYSAVSVHVRGSVVLHRLYEKNRANDNAPGDFEE
TH_1116|M.thermoresistible__bu      IDSLVQAGLSPEDAFDTYSAVSVHVRGSVVLERLHEKTQDLFNGG---DE
MAB_1508c|M.abscessus_ATCC_199      VRTLIGVGFSPDNALDVYFALSLHIRGVVVLEHMDTVMPASGEAR-----
                                    :  *: .*:* ::*:* * *:*:*:** ***.::         .      

MMAR_4019|M.marinum_M               AMNIDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAK
MUL_3884|M.ulcerans_Agy99           AMNIDPLTTPLLAQVSGKGHRIATPDEANFEYGLDCILDHAGRLIDERAK
MAV_1586|M.avium_104                AVAIDPEKTPLLAQVTRIGHRIGAPDETNFEYGLTCILDHASRLIEE-GK
Mb1388c|M.bovis_AF2122/97           PVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSK
Rv1353c|M.tuberculosis_H37Rv        PVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSK
Mflv_4355|M.gilvum_PYR-GCK          TMAIDPETAPLLAAVTQKGHHLSASDDRNFEFGLDCILENAARLIEK-AK
Mvan_1989|M.vanbaalenii_PYR-1       TMTIDPESAPLLAAVTQKGHHLSASDDRNFEYGLECILDHAARLIEQNAK
MSMEG_2225|M.smegmatis_MC2_155      AMVIDPETTPLLAQVTSEGHRIGAADEQNFEYGLKCILDHAARLIEE--K
TH_1116|M.thermoresistible__bu      PSAVDPASTPIIAELLAKGHRLAEADERNFEYTLECILDHAERLIEERAA
MAB_1508c|M.abscessus_ATCC_199      SLVPSATLAPTLHELASRGHSIATISDANFDFTVEAIIERAENLLAQDIA
                                    .   ..  :* :      ** :.  .: **:: : .*::.* .*: :   

MMAR_4019|M.marinum_M               AAKSAPSR-PRKAAKPPAPRTRAKATTR-
MUL_3884|M.ulcerans_Agy99           AAKSAPSR-PRKAAKPPAPRTRAKATTR-
MAV_1586|M.avium_104                GAKAGPSR-QRKPAKSSAARGRTKAPANR
Mb1388c|M.bovis_AF2122/97           AAGEVAVRRPTATADAPTPGARAKAVAR-
Rv1353c|M.tuberculosis_H37Rv        AAGEVAVRRPTATADAPTPGARAKAVAR-
Mflv_4355|M.gilvum_PYR-GCK          TTRKAP--------------ARKR-----
Mvan_1989|M.vanbaalenii_PYR-1       PARKATPA---------KSTARKR-----
MSMEG_2225|M.smegmatis_MC2_155      PAKKTR---------------RKVTAG--
TH_1116|M.thermoresistible__bu      GGTRK------------------------
MAB_1508c|M.abscessus_ATCC_199      AREAS------------------------