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KHLLELARRVGVDHVTMRGLAAEAGTSASSVYYHVKDKAALMDLLAESVIESIEVPADGDWRRRISALYT NAWTVMYDIPGVAAMLQQRPLAGAAHAMDRTARAIMAEAGWDGEQISRAHAVLYIHLLGSIQLAHHLRDS GIDGGSDDGAHSVFQHGLRVILTGLQHTSPLP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1322 | - | - | 100% (173) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4355 | - | 1e-06 | 23.12% (160) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3625 | - | 1e-06 | 26.00% (100) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 8e-05 | 24.66% (146) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1353c | - | 9e-05 | 24.66% (146) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0856c | - | 1e-06 | 30.66% (137) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 2e-10 | 29.55% (132) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 2e-06 | 24.21% (95) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2583 | - | 5e-10 | 27.03% (185) | putative transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3622 | - | 2e-10 | 29.55% (132) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5480 | - | 4e-71 | 77.25% (167) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1322|M.gilvum_PYR-GCK ----------------------------------MKHLLELARRVGVDHV
Mvan_5480|M.vanbaalenii_PYR-1 -------------MARTRRAGAALPYGALDRDHLVKHLLELARRVGVENV
MMAR_3679|M.marinum_M --------MFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MUL_3622|M.ulcerans_Agy99 MISIRTSYVFTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGL
MSMEG_2583|M.smegmatis_MC2_155 ----------------------MPRQRSLTRPQIAAAALEVVDTDGLGSL
Mb1388c|M.bovis_AF2122/97 -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
Rv1353c|M.tuberculosis_H37Rv -------------MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNL
MAB_0856c|M.abscessus_ATCC_199 --------------------------MILNRETIARAGLALLDEKGSDGL
MAV_5055|M.avium_104 -----------------------MRRAGLKREAVVRAAVKIADAEGIEAI
. : . :
Mflv_1322|M.gilvum_PYR-GCK TMRGLAAEAGTSASSVYYHVKDKAALMDLLAESVIESIEVPA----DGDW
Mvan_5480|M.vanbaalenii_PYR-1 TMRALATEAGTSASSVYYHVKDKAALLDLLAESVIESIEVPT----EGDW
MMAR_3679|M.marinum_M SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAP---TDDW
MUL_3622|M.ulcerans_Agy99 SMRSLAAALGTGPMTLYNYVRDRRELEALVADAVVADVKVPAP---IDDW
MSMEG_2583|M.smegmatis_MC2_155 SMRTVARRLGMGTMSLYRYVADRDELEAMVVELVLESVDLRPP---AGSA
Mb1388c|M.bovis_AF2122/97 SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
Rv1353c|M.tuberculosis_H37Rv SMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDW
MAB_0856c|M.abscessus_ATCC_199 TMRALAASLGVQAPALYWHVKNRRELIDLMGEVIVQEAYESFDLS-TAPW
MAV_5055|M.avium_104 SMRRVSQALGVTPMALYRYLPDKDALIDVVVDESLAVVPVPDP---SGSV
:* :. * ::* :. .: * : : :
Mflv_1322|M.gilvum_PYR-GCK RRRISALYTNAWTVMYDIP-GVAAMLQQRPLAGAAHAMD----RTARAIM
Mvan_5480|M.vanbaalenii_PYR-1 EQRTRALYTNAWKVMIAIP-GIAAMLQQRPLTGAADAVD----RTVKAIM
MMAR_3679|M.marinum_M RADVHAIATAMWETMRQHPNAIPLVLTRRTVSASSYMVA----DRLIAAL
MUL_3622|M.ulcerans_Agy99 RADVHAIATAMWETMRQHPNAIPLVLTRRTVWASSYMVA----DRLIAAL
MSMEG_2583|M.smegmatis_MC2_155 RHRILVLAERVRDATARHPAVVPLLLAHRHRLPASLRWG----EAVLGVL
Mb1388c|M.bovis_AF2122/97 RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
Rv1353c|M.tuberculosis_H37Rv RETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANL
MAB_0856c|M.abscessus_ATCC_199 DVFLANGARAFRQAMLRYHQGARILAGTFATNAADMVEP------LLDAM
MAV_5055|M.avium_104 TAELLRCFGGLYDLLLDHPGLARAAGERPLEGPFATRLG----NNVLTLL
:
Mflv_1322|M.gilvum_PYR-GCK AEAGWDGEQISRAHAVLYIHLLGSIQLAHHLRDSGID-------------
Mvan_5480|M.vanbaalenii_PYR-1 AESGWTADEVAAAHVVLYIHLLGSVQLEHHLRHSGIE-------------
MMAR_3679|M.marinum_M GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
MUL_3622|M.ulcerans_Agy99 GRSGVGDADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIG
MSMEG_2583|M.smegmatis_MC2_155 AEAGYAGKRRVYAFRALLACTFGALEIQHHSALSGPG--------TRALA
Mb1388c|M.bovis_AF2122/97 VTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAI
Rv1353c|M.tuberculosis_H37Rv VTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAI
MAB_0856c|M.abscessus_ATCC_199 TSAGFTVREAARLSPAIYHYTIG-FTIEQQSRDGSEYPGPNPYTEENLLA
MAV_5055|M.avium_104 QHNKIDEADAANLLVSAFSLTLGCALYRTSRSGRTAS---------SRLS
*
Mflv_1322|M.gilvum_PYR-GCK ---------------GGSDDGAHSVFQHGLRVILTGLQ--HTSPLP----
Mvan_5480|M.vanbaalenii_PYR-1 ---------------IKSDDGAESVFQHGLRVILAGLRSCHTETSTPTT-
MMAR_3679|M.marinum_M GLAGAEHPHIAALAQASQRSTPAADFERALDILLAGIESFERRRDRR---
MUL_3622|M.ulcerans_Agy99 GLAGAEHPHIAALAQASQRSTPAADFERALDILLAGIESFERRRDRR---
MSMEG_2583|M.smegmatis_MC2_155 ELPADEFPRLSETAAAARGIGAGDEFRHGLEILLRGLQI-----------
Mb1388c|M.bovis_AF2122/97 DPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGE
Rv1353c|M.tuberculosis_H37Rv DPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGE
MAB_0856c|M.abscessus_ATCC_199 KLDLHKYPAVAEAFSEIYDPDFDADFEDGLTIIIDGLRARLHAKRKSAAP
MAV_5055|M.avium_104 QVGDEAPAVRRLRGRLTVASADDTVFRDALTRLIAGYVTTAAKTGGRRR-
*. .* ::
Mflv_1322|M.gilvum_PYR-GCK ------------------------
Mvan_5480|M.vanbaalenii_PYR-1 ------------------------
MMAR_3679|M.marinum_M ------------------------
MUL_3622|M.ulcerans_Agy99 ------------------------
MSMEG_2583|M.smegmatis_MC2_155 ------------------------
Mb1388c|M.bovis_AF2122/97 VAVRRPTATADAPTPGARAKAVAR
Rv1353c|M.tuberculosis_H37Rv VAVRRPTATADAPTPGARAKAVAR
MAB_0856c|M.abscessus_ATCC_199 RVTTRR------------------
MAV_5055|M.avium_104 ------------------------