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FTLRTMYLSTVWEGDVRARFTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEAL VADAVVADVKVPAPTDDWRADVHAIATAMWETMRQHPNAIPLVLTRRTVSASSYMVADRLIAALGRSGVG DADLLASFRGVLGLVMGSAQAELAGPLAGTGREKEQVAVAARIGGLAGAEHPHIAALAQASQRSTPAADF ERALDILLAGIESFERRRDRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3679 | - | - | 100% (232) | putative regulatory protein |
| M. marinum M | MMAR_4019 | - | 9e-08 | 26.85% (149) | transcriptional regulatory protein |
| M. marinum M | MMAR_1597 | - | 3e-05 | 32.18% (87) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 6e-07 | 26.17% (149) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2560 | - | 8e-15 | 29.17% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 6e-07 | 26.17% (149) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4687 | - | 6e-14 | 26.42% (212) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5055 | - | 1e-10 | 25.87% (143) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2583 | - | 2e-23 | 31.19% (202) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_0654 | - | 1e-10 | 27.09% (203) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3622 | - | 1e-125 | 99.14% (232) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4078 | - | 2e-16 | 29.73% (222) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3679|M.marinum_M ------------------------MFTLRTMYLSTVWEGDVR------AR
MUL_3622|M.ulcerans_Agy99 ----------------MISIRTSYVFTLRTMYLSTVWEGDVR------AR
MSMEG_2583|M.smegmatis_MC2_155 --------------------------------------MPRQ------RS
Mflv_2560|M.gilvum_PYR-GCK MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQR
Mvan_4078|M.vanbaalenii_PYR-1 -----------MVTRGAGPERSSAGDPVRTLKLLWRTPGEARTSRGPRQR
Mb1388c|M.bovis_AF2122/97 ---------------------------------MQTTPGKRQ--RRQRGS
Rv1353c|M.tuberculosis_H37Rv ---------------------------------MQTTPGKRQ--RRQRGS
MAB_4687|M.abscessus_ATCC_1997 --------------------------------MTDERRMRGR------PP
TH_0654|M.thermoresistible__bu ------------------------------------------------VQ
MAV_5055|M.avium_104 ---------------------------------------MRR------AG
MMAR_3679|M.marinum_M FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MUL_3622|M.ulcerans_Agy99 FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MSMEG_2583|M.smegmatis_MC2_155 LTRPQIAAAALEVVDTDGLGSLSMRTVARRLGMGTMSLYRYVADRDELEA
Mflv_2560|M.gilvum_PYR-GCK TSVDAVVAAAVGIADTQGLSAVTIRAVAGVLGLAPMAIYTYVPGKAELLD
Mvan_4078|M.vanbaalenii_PYR-1 TTVDAVVAAAIEIADADGLGAVTIRAVATRLGIATMATYTYVPGKAELLD
Mb1388c|M.bovis_AF2122/97 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
Rv1353c|M.tuberculosis_H37Rv INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
MAB_4687|M.abscessus_ATCC_1997 LPMETIVDAALQIVDEEGGEALSMRALARRLDSGTATIYRHFANRTEVVA
TH_0654|M.thermoresistible__bu LRKSDVVDAATAILDNYGIADLTTRRLARELGVTAGALYWHFANKQELLG
MAV_5055|M.avium_104 LKREAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPDKDALID
: .* : : . :: :. *. : * :. : :
MMAR_3679|M.marinum_M LVADAVVADVKVPAPTDD---WRADVHAIATAMWETMRQHPNAIPLVLTR
MUL_3622|M.ulcerans_Agy99 LVADAVVADVKVPAPIDD---WRADVHAIATAMWETMRQHPNAIPLVLTR
MSMEG_2583|M.smegmatis_MC2_155 MVVELVLESVDLRPPAGS---ARHRILVLAERVRDATARHPAVVPLLLAH
Mflv_2560|M.gilvum_PYR-GCK LMLDSVYGQMSRGDLSGLP--WRHRVTAIADENRALLDEHPWVTQLATTR
Mvan_4078|M.vanbaalenii_PYR-1 LMLDTVYRQMPRRDLSGMA--WRDRVSAIAGENRELLEQHPWVAQLATTR
Mb1388c|M.bovis_AF2122/97 AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
Rv1353c|M.tuberculosis_H37Rv AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
MAB_4687|M.abscessus_ATCC_1997 HVVDRVFGEVQLDDPALARMPWQDACIVSSRALFDALRRHPNVAMLLADQ
TH_0654|M.thermoresistible__bu AVADRILTPVPAGEPEPG---WAERISSTAGRLRDALLSHTDGAELVSAT
MAV_5055|M.avium_104 VVVDESLAVVPVPDPSGS---VTAELLRCFGGLYDLLLDHPGLARAAGER
: : :.
MMAR_3679|M.marinum_M RTVSAS-SYMVADRLIA-ALGRSGVGDADLLASFRGVLGLVMGSAQAELA
MUL_3622|M.ulcerans_Agy99 RTVWAS-SYMVADRLIA-ALGRSGVGDADLLASFRGVLGLVMGSAQAELA
MSMEG_2583|M.smegmatis_MC2_155 RHRLPA-SLRWGEAVLG-VLAEAGYAGKRRVYAFRALLACTFGALEIQHH
Mflv_2560|M.gilvum_PYR-GCK PPLGPG-TAAKYDHELR-AFDGLGLSDLDMDSALTYVLGFVTSVARIADD
Mvan_4078|M.vanbaalenii_PYR-1 PPLGPG-MIAKYEHELC-AFDGLGLSDLDMDSALTYVLGFVMSVARIAID
Mb1388c|M.bovis_AF2122/97 AALSPK-TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVL
Rv1353c|M.tuberculosis_H37Rv AALSPK-TARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVL
MAB_4687|M.abscessus_ATCC_1997 IPVGPN-VFMIREHTLT-LCLQAGFSPAEAIRIYMTLGRYVLGFANQIGA
TH_0654|M.thermoresistible__bu FAAGQSRVLDEILARFAAAAAAAGLEGSRAVLAARTIVHYVLGFTGDEQS
MAV_5055|M.avium_104 PLEGPF-ATRLGNNVLT-LLQHNKIDEADAANLLVSAFSLTLGCALYRTS
:
MMAR_3679|M.marinum_M GPLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQAS-----QRS
MUL_3622|M.ulcerans_Agy99 GPLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQAS-----QRS
MSMEG_2583|M.smegmatis_MC2_155 SALSGPG--------TRALA-----ELPADEFPRLSETAAAA-----RGI
Mflv_2560|M.gilvum_PYR-GCK AREARRDSGVSDQAWWDRAGPLLAEVFDDEKFPLAARIGAAAGQAFGSAY
Mvan_4078|M.vanbaalenii_PYR-1 TNAARADSGVTDDTWWEQAGPVLATVFDADEFPLAARVGEAAGRALGGAY
Mb1388c|M.bovis_AF2122/97 DRLSRKSQSAGSGPSAIEHP----VAIDPATTPLLAHATGRG---HRIGA
Rv1353c|M.tuberculosis_H37Rv DRLSRKSQSAGSGPSAIEHP----VAIDPATTPLLAHATGRG---HRIGA
MAB_4687|M.abscessus_ATCC_1997 EHRASEADIAMLTRLVENID--------LASYPSTLATAGVT------LV
TH_0654|M.thermoresistible__bu RLQWDAAG------------------------AEVAEPPADD--------
MAV_5055|M.avium_104 RSGRTASSRLSQVG---------------DEAPAVRRLRGRLT----VAS
.
MMAR_3679|M.marinum_M TPAADFERALDILLAGIESFERRRDRR-----------------------
MUL_3622|M.ulcerans_Agy99 TPAADFERALDILLAGIESFERRRDRR-----------------------
MSMEG_2583|M.smegmatis_MC2_155 GAGDEFRHGLEILLRGLQI-------------------------------
Mflv_2560|M.gilvum_PYR-GCK DADHAYRFGLARVLDGLEPVINRTAR------------------------
Mvan_4078|M.vanbaalenii_PYR-1 NAEHAYRFGLARVLDGLAPVIGDRARGSGRSPAN----------------
Mb1388c|M.bovis_AF2122/97 PDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAK
Rv1353c|M.tuberculosis_H37Rv PDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAK
MAB_4687|M.abscessus_ATCC_1997 PLDEEFDFGLGLIVAGLEGLRHGE--------------------------
TH_0654|M.thermoresistible__bu NPSARFAFGLNLLINGIAAEIDAAARKSE---------------------
MAV_5055|M.avium_104 ADDTVFRDALTRLIAGYVTTAAKTGGRRR---------------------
: .* ::
MMAR_3679|M.marinum_M ----
MUL_3622|M.ulcerans_Agy99 ----
MSMEG_2583|M.smegmatis_MC2_155 ----
Mflv_2560|M.gilvum_PYR-GCK ----
Mvan_4078|M.vanbaalenii_PYR-1 ----
Mb1388c|M.bovis_AF2122/97 AVAR
Rv1353c|M.tuberculosis_H37Rv AVAR
MAB_4687|M.abscessus_ATCC_1997 ----
TH_0654|M.thermoresistible__bu ----
MAV_5055|M.avium_104 ----