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MMAPQVRQTARELRRLQTRERILGAAIAEFQASGMAGADIGAIVSAAGVAHGTFFFHFPSKEHVLLELER REESRMATEFARYLDKKHDLASALAKVVELISALERRFGPLLFKELLALHFSPTRPSTDEWSDHPVIVSL VGAIERARGDGEIHPEVDAFYSAAFFLLGIYGVLTTVARGDIRDAMLANLITTARRGLETR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4973 | - | - | 100% (201) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1513 | - | 1e-54 | 54.97% (191) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0989 | - | 6e-09 | 36.17% (94) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 3e-05 | 38.33% (60) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1774 | - | 1e-94 | 84.00% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 3e-05 | 38.33% (60) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_00316 | - | 2e-05 | 41.27% (63) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1379c | - | 9e-08 | 33.67% (98) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 3e-43 | 43.88% (196) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2459 | - | 2e-58 | 57.51% (193) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 2e-57 | 56.84% (190) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1661 | - | 1e-60 | 57.00% (200) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 8e-43 | 43.37% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3605|M.bovis_AF2122/97 ---------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRA
Rv3574|M.tuberculosis_H37Rv ---------MAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRA
Mvan_4973|M.vanbaalenii_PYR-1 --------MMAPQVRQTARELRRLQTRERILGAAIAEFQASGMAGADIGA
Mflv_1774|M.gilvum_PYR-GCK ---------MTPQIKQSARELRRLQTRERILGAAIAEFQASGMAGADVGA
MAV_2459|M.avium_104 -----------MADRLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGA
MSMEG_6604|M.smegmatis_MC2_155 ---------MAGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADADVGT
TH_1661|M.thermoresistible__bu ---------MARAEKPSAREAKRLQTRERLLGAAIAEFKRTGMAEADVRA
MMAR_0249|M.marinum_M -MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAA
MUL_4864|M.ulcerans_Agy99 -MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAA
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
MAB_1379c|M.abscessus_ATCC_199 -----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIAD
. * .::..: * . :
Mb3605|M.bovis_AF2122/97 VADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAK-------TDRSAV
Rv3574|M.tuberculosis_H37Rv VADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAK-------TDRSAV
Mvan_4973|M.vanbaalenii_PYR-1 IVSAAGVAHGTFFFHFPSKEHVLLELERREESRMATE-------FARYLD
Mflv_1774|M.gilvum_PYR-GCK IVSAAGVAHGTFFFHFPSKEHVLLELERREEARMATE-------FVRYLR
MAV_2459|M.avium_104 IVAAAGVAHGTFFFHFPTKEHVLLELERREEERIAKQ-------FAQFLK
MSMEG_6604|M.smegmatis_MC2_155 IVAAAGVAHGTFFFHFPTKEHVLLELEQREEERIAKQ-------FAQFVK
TH_1661|M.thermoresistible__bu IVAAAGVAHGTFFFHFPTKEHVLLELERREEERIARQ-------FSRFLE
MMAR_0249|M.marinum_M IAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAK-------LRDPTA
MUL_4864|M.ulcerans_Agy99 IAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAK-------LRDPTA
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGY----VLLKSAG
MAB_1379c|M.abscessus_ATCC_199 IVRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAPTSLA
:. ..:. **.: :* :* : :
Mb3605|M.bovis_AF2122/97 AGATPFQRLNFMVGKLNRAMQRN-PLLTEAMTRAYVFADASAASEVDQVE
Rv3574|M.tuberculosis_H37Rv AGATPFQRLNFMVGKLNRAMQRN-PLLTEAMTRAYVFADASAASEVDQVE
Mvan_4973|M.vanbaalenii_PYR-1 KKHDLASALAKVVELISALERRFGPLLFKELLALHFSPTRPSTDEWSDHP
Mflv_1774|M.gilvum_PYR-GCK RSHDLTAALTKVVGLIAGLEQRLGPVLFRELLALHFSPTRPSDDDWSDHP
MAV_2459|M.avium_104 SEHDLASALNEAVRLVVGLERRLGDMLFNDFLALHFSQTRPQTEDGRDHP
MSMEG_6604|M.smegmatis_MC2_155 KPHDLEAALREIVRLVIGLERRLGDLLFKDFLALHFSQTRPRVDEGMEHP
TH_1661|M.thermoresistible__bu TEHDLVGTLKEAVRLVLDIEDRLGPVLFKDFLALHFSPTRPPAEEGQDHP
MMAR_0249|M.marinum_M DPTDLVSVLSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHP
MUL_4864|M.ulcerans_Agy99 DSTDLVSVLSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHP
MLBr_00316|M.leprae_Br4923 PGEALFTYLRSLVLHWGATDRGLVDALAGAG-GIDILGVAPDAED----A
MAB_1379c|M.abscessus_ATCC_199 EYRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAA
: :
Mb3605|M.bovis_AF2122/97 KLIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTR-RASATDVS
Rv3574|M.tuberculosis_H37Rv KLIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTR-RASATDVS
Mvan_4973|M.vanbaalenii_PYR-1 VIVSLVGAIERARGDGEIHPEVDAFYSAAFFLLGIYGVLTT-VARGDIRD
Mflv_1774|M.gilvum_PYR-GCK VIVSLVREIERARGDGEVHPEVDAFFSAAFFLLGVYGVLTT-VTSSDTRD
MAV_2459|M.avium_104 LIVLVANEIEGAQQRGETDPHVNPMNSAVFFLLGLYALLIT-TNHWPTGH
MSMEG_6604|M.smegmatis_MC2_155 VIARVTEEIEAARQRGDVAADVNPVNSAVFFLLGFYALLVT-TNDWPTRD
TH_1661|M.thermoresistible__bu LIVSVAEEIERAQRAGEVDAEVNPWNSAVFFLLGLYALLTT-THAWPNRA
MMAR_0249|M.marinum_M LAEFVIETIARAQRANRVPPDADAGELGVIFLTGLFALLATGATTPDART
MUL_4864|M.ulcerans_Agy99 LAEFVIETIAQAQRADRVAPDADAGELGVIFLTGLFALLATGATTPDART
MLBr_00316|M.leprae_Br4923 FLTILSDLLYAAQYAGTARTDVG--------VREVKSILVGCQAMEAYNS
MAB_1379c|M.abscessus_ATCC_199 AIQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAFE
: : .
Mb3605|M.bovis_AF2122/97 KRLDLAVRLLIGDQDSA-------
Rv3574|M.tuberculosis_H37Rv KRLDLAVRLLIGDQDSA-------
Mvan_4973|M.vanbaalenii_PYR-1 AMLANLITTARRGLETR-------
Mflv_1774|M.gilvum_PYR-GCK AMLANLITTARRGLESR-------
MAV_2459|M.avium_104 ALLEDYVARTLRSLKP--------
MSMEG_6604|M.smegmatis_MC2_155 EVLDDYVRRTLRSMRP--------
TH_1661|M.thermoresistible__bu GMVDDFVANTLRSLRPRLTRR---
MMAR_0249|M.marinum_M ALLNRFVTTVVHGMEAR-------
MUL_4864|M.ulcerans_Agy99 ALLNGFVTTVVHGMEAR-------
MLBr_00316|M.leprae_Br4923 ALAERVTDVVVDGLRAAR------
MAB_1379c|M.abscessus_ATCC_199 QLAHAVREILYYGLASDHHPQIAD
. .