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VTATPSLHEQRRRSTREALRRAALASFAARGFANVTVTELARAAGVTERTFFRHFPTKEAVLFQDYETQV EWLAAALARRPGSESVFDAVRAAIAEFPYDLEVVRQAATARSELISAERIAGHLRVVQSSFADVLTGHIR TRYAGTADIDLVADVAGAALAAALVVAVEHWGRNGCVDDLGEITSASMAVLRSGFARLT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0989 | - | - | 100% (199) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5077 | - | 6e-28 | 35.11% (188) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1927 | - | 6e-15 | 30.56% (180) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 2e-32 | 38.74% (191) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1676 | - | 2e-29 | 36.84% (190) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 2e-32 | 38.74% (191) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_02677 | - | 2e-06 | 33.33% (90) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3837 | - | 2e-12 | 25.29% (174) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_2812 | - | 2e-78 | 73.87% (199) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2788 | - | 1e-76 | 73.23% (198) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 1e-13 | 25.79% (190) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3524 | - | 4e-13 | 28.87% (194) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2933 | - | 3e-78 | 73.37% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2812|M.marinum_M MTVPTNRHELRRRSTHEALRRAALKSFACKGFAQVTVTELAREAGVTERT
MUL_2933|M.ulcerans_Agy99 MTVPTNRHELRRRSTHEALRRAALKSFARKGFAQVTVTELAREAGVTERT
MAV_2788|M.avium_104 MTGPGNRHEQRRRSTHEALRQAALKSFARKGFANVTVTELAREAGVTERT
Mvan_0989|M.vanbaalenii_PYR-1 MTATPSLHEQRRRSTREALRRAALASFAARGFANVTVTELARAAGVTERT
Mb3860c|M.bovis_AF2122/97 MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
Rv3830c|M.tuberculosis_H37Rv MVRPP--QTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
Mflv_1676|M.gilvum_PYR-GCK MVRPA--QTVRSERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRT
MAB_3837|M.abscessus_ATCC_1997 MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGIARRT
MSMEG_1420|M.smegmatis_MC2_155 -MSEGSRAGRRRSTTQDHIAGVAIDLFAARGFDAVSVDDVAAAAGISRRT
TH_3524|M.thermoresistible__bu ---------VRGHRNREALIAAAIDLFTVNGYEQTTVEQIAEAAGVAPRT
MLBr_02677|M.leprae_Br4923 MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEIAKEADTTRGA
* .:: : . : .* . . ::* *. : :
MMAR_2812|M.marinum_M FFRHFPTKEAVLFQDYENQLEWLAQALAQRPVSEPLFDAVLASVAAFP-H
MUL_2933|M.ulcerans_Agy99 FFRHFPTKEAVLFQDYENQLEWLARALAQRPVSEPLFDAVLASVAAFP-H
MAV_2788|M.avium_104 FFRHFPTKESVLFQDYETQLEWLAEALAQRPPSESLFDAVLASVAAFP-H
Mvan_0989|M.vanbaalenii_PYR-1 FFRHFPTKEAVLFQDYETQVEWLAAALARRPGSESVFDAVRAAIAEFP-Y
Mb3860c|M.bovis_AF2122/97 FYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFP-Y
Rv3830c|M.tuberculosis_H37Rv FYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFP-Y
Mflv_1676|M.gilvum_PYR-GCK FYRHFASKHDLLFADYDAGLHWFRAALATRSPEDPILDTVQAAIMAAP-Y
MAB_3837|M.abscessus_ATCC_1997 VFRYYSSKNAIVWGDFDSHLGVMRALLDETADTVDTSTALRQAVLTFNDF
MSMEG_1420|M.smegmatis_MC2_155 LFRYYASKSAIPWGDFDSHLQHLQNLLRTLSSEVSLGDALREALLTFNTY
TH_3524|M.thermoresistible__bu FFRHFAAKEDILFHGYADRLAEATRRFRAARSG-SLWKALAEASEAVATA
MLBr_02677|M.leprae_Br4923 VYHQFTDK-AALFRDVVETVEQDAMAQIASVVASSGAKTPVDAIRAKVDA
.:: : * : . : : :
MMAR_2812|M.marinum_M DLEVVRQAATARSELISADRIA--NHLRVVQSSFAQVLTAFVRDR---YA
MUL_2933|M.ulcerans_Agy99 DLEVVRQAATARSELISADRIA--NHLRVVQSSFAQVLTAFVRNR---YA
MAV_2788|M.avium_104 DLEVVRQAATARAELISAERIA--GHLRVVQSSFARVLTDFVRAR---NP
Mvan_0989|M.vanbaalenii_PYR-1 DLEVVRQAATARSELISAERIA--GHLRVVQSSFADVLTGHIRTR---YA
Mb3860c|M.bovis_AF2122/97 DVDAVTKIASLRRGELEPSRIV--RHMREVEADFADAIQAQLRRRNCDIA
Rv3830c|M.tuberculosis_H37Rv DVDAVTKIASLRRGELEPSRIV--RHMREVEADFADAIQAQLRRRNCDIA
Mflv_1676|M.gilvum_PYR-GCK DDWAVTKIAAMRSQELDAGRIV--RHIRQVEADFADAIDEHLARADGASP
MAB_3837|M.abscessus_ATCC_1997 PVDETPRHRMRMRMILEVPALQ--AYSMLMYTGWRDVIAQFVARR----S
MSMEG_1420|M.smegmatis_MC2_155 ADHEMAEHRQRMRVILETEELQ--AYSMTMYAGWRTVIAEYVADR----L
TH_3524|M.thermoresistible__bu IAENPGIFLVRARMYGELPALR--ATMLRINDDWIDQMTTEVARWLG---
MLBr_02677|M.leprae_Br4923 WLEGLADPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQLLSEASRA
: : : :
MMAR_2812|M.marinum_M DVANVDLVAEVAGATIAAALVVAVENWGR--NGCAVDLGELVAASLDLVR
MUL_2933|M.ulcerans_Agy99 DVANVDLVAEVAGATIAAALVVAVENWGR--YGCAEDLGELVAASLDLVR
MAV_2788|M.avium_104 QLANIDLFAEVAGSAVAAALVAAVENWGR--RGCSGELGDDVTASLALIR
Mvan_0989|M.vanbaalenii_PYR-1 GTADIDLVADVAGAALAAALVVAVEHWGR--NGCVDDLGEITSASMAVLR
Mb3860c|M.bovis_AF2122/97 GAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLR
Rv3830c|M.tuberculosis_H37Rv GAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLR
Mflv_1676|M.gilvum_PYR-GCK GT-DERMRTTVTARCIAAAVFGAMEVWMLGEDSSLPELDRLCRHALDLLR
MAB_3837|M.abscessus_ATCC_1997 GTDPGSLLPQTVAWTLLGVALAAYEQWLAD---ESSKLTTLLGKGFDAAE
MSMEG_1420|M.smegmatis_MC2_155 GMSTTDLMPQTVAWLMLGVALSAYENWLAD---ESVSLRGAIAAAFEVAR
TH_3524|M.thermoresistible__bu SDAAVDVRPRLAATVINGANRTAIDLWVS--ADGKGDLVELMADAVRLVR
MLBr_02677|M.leprae_Br4923 RQLAQPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGAAPTHREHVAR
: . .. . . .
MMAR_2812|M.marinum_M SGLAPLS------------------------------
MUL_2933|M.ulcerans_Agy99 SGLAPLS------------------------------
MAV_2788|M.avium_104 SGLAPLA------------------------------
Mvan_0989|M.vanbaalenii_PYR-1 SGFARLT------------------------------
Mb3860c|M.bovis_AF2122/97 VGISDTWTTLTVSS-----------------------
Rv3830c|M.tuberculosis_H37Rv VGISDTWTTLTVSS-----------------------
Mflv_1676|M.gilvum_PYR-GCK TGIADPA------------------------------
MAB_3837|M.abscessus_ATCC_1997 VGLRALR------------------------------
MSMEG_1420|M.smegmatis_MC2_155 PGLDALQPAH---------------------------
TH_3524|M.thermoresistible__bu PTLDRIERESRTVANPVRRRDVV--------------
MLBr_02677|M.leprae_Br4923 PSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL