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ADRLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGAIVAAAGVAHGTFFFHFPTKEHVLLELERREEE RIAKQFAQFLKSEHDLASALNEAVRLVVGLERRLGDMLFNDFLALHFSQTRPQTEDGRDHPLIVLVANEI EGAQQRGETDPHVNPMNSAVFFLLGLYALLITTNHWPTGHALLEDYVARTLRSLKP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2459 | - | - | 100% (197) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4190 | - | 8e-36 | 46.07% (178) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2788 | - | 2e-09 | 43.42% (76) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 2e-05 | 27.52% (149) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4907 | - | 1e-75 | 71.94% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 2e-05 | 27.52% (149) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1379c | - | 2e-07 | 32.43% (74) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 1e-39 | 46.84% (190) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 6e-84 | 76.53% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1661 | - | 1e-79 | 74.49% (196) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 2e-39 | 46.32% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1513 | - | 5e-77 | 72.96% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0068c|M.bovis_AF2122/97 ----------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-VPVDEI
Rv0067c|M.tuberculosis_H37Rv ----------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-VPVDEI
MAV_2459|M.avium_104 ----------MADRLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGAI
MSMEG_6604|M.smegmatis_MC2_155 --------MAGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADADVGTI
Mflv_4907|M.gilvum_PYR-GCK ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGMAEADVSTI
Mvan_1513|M.vanbaalenii_PYR-1 ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGKDESDVGAI
TH_1661|M.thermoresistible__bu --------MARAEKPSAREAKRLQTRERLLGAAIAEFKRTGMAEADVRAI
MMAR_0249|M.marinum_M MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MUL_4864|M.ulcerans_Agy99 MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MAB_1379c|M.abscessus_ATCC_199 ----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIADI
. . ..* .:: .* : * : *
Mb0068c|M.bovis_AF2122/97 ARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDAL
Rv0067c|M.tuberculosis_H37Rv ARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDAL
MAV_2459|M.avium_104 VAAAGVAHGTFFFHFPTKEHVLLELERREEERIAKQFAQFLKSEHD---L
MSMEG_6604|M.smegmatis_MC2_155 VAAAGVAHGTFFFHFPTKEHVLLELEQREEERIAKQFAQFVKKPHD---L
Mflv_4907|M.gilvum_PYR-GCK VGAAGVAHGTFFFHFPTKEHVLLELERREEDRIAKRFATFTKTHHD---L
Mvan_1513|M.vanbaalenii_PYR-1 VAAAGVAHGTFFFHFPTKEHVLLELERREEDRMAKRFATFTKTHHD---L
TH_1661|M.thermoresistible__bu VAAAGVAHGTFFFHFPTKEHVLLELERREEERIARQFSRFLETEHD---L
MMAR_0249|M.marinum_M AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADPTD---L
MUL_4864|M.ulcerans_Agy99 AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADSTD---L
MAB_1379c|M.abscessus_ATCC_199 VRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAPTS--L
. .*:. **.: :* :*. :. : : *
Mb0068c|M.bovis_AF2122/97 FAFLRSMVLQWGATDRGLV----EALAG--VGIEISSAAPEAEAD----F
Rv0067c|M.tuberculosis_H37Rv FAFLRSMVLQWGATDRGLV----EALAG--VGIEISSAAPEAEAD----F
MAV_2459|M.avium_104 ASALNEAVRLVVGLERRLG----DMLFNDFLALHFSQTRPQTEDGRDHPL
MSMEG_6604|M.smegmatis_MC2_155 EAALREIVRLVIGLERRLG----DLLFKDFLALHFSQTRPRVDEGMEHPV
Mflv_4907|M.gilvum_PYR-GCK SAVLREAADLVLGLERRLG----VVLFKDFLALHFSPTRPPAEHGGDHPV
Mvan_1513|M.vanbaalenii_PYR-1 ASALREAAHLVMGLERRLG----VVLFKDFLALHFSPTRPPAEHGDDHPL
TH_1661|M.thermoresistible__bu VGTLKEAVRLVLDIEDRLG----PVLFKDFLALHFSPTRPPAEEGQDHPL
MMAR_0249|M.marinum_M VSVLSSLVHQVVAVERRLG----PVVFRDMLGLHFAPTRPVEDQLGEHPL
MUL_4864|M.ulcerans_Agy99 VSVLSSLAHQVVAVERRLG----PLVFRDMLGLHFAPTRPVEDQLGEHPL
MAB_1379c|M.abscessus_ATCC_199 AEYRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAA
. * . . .
Mb0068c|M.bovis_AF2122/97 LDLLTDLLRAAQRAGTVRPDVDV-----LEVKT-LLVGCQAMQSYNAELA
Rv0067c|M.tuberculosis_H37Rv LDLLTDLLRAAQRAGTVRPDVDV-----LEVKT-LLVGCQAMQSYNAELA
MAV_2459|M.avium_104 IVLVANEIEGAQQRGETDPHVNP-----MNSAVFFLLGLYALLITTNHWP
MSMEG_6604|M.smegmatis_MC2_155 IARVTEEIEAARQRGDVAADVNP-----VNSAVFFLLGFYALLVTTNDWP
Mflv_4907|M.gilvum_PYR-GCK VVLVAAQIEHARQRGETAADVTP-----MNSAIYFLLGLYALLVTTDEST
Mvan_1513|M.vanbaalenii_PYR-1 VVLVADQIDNARQRGDTAADVTP-----MNSAIYFLLGLYALLITTDDST
TH_1661|M.thermoresistible__bu IVSVAEEIERAQRAGEVDAEVNP-----WNSAVFFLLGLYALLTTTHAWP
MMAR_0249|M.marinum_M AEFVIETIARAQRANRVPPDADA-----GELGVIFLTGLFALLATGATTP
MUL_4864|M.ulcerans_Agy99 AEFVIETIAQAQRADRVAPDADA-----GELGVIFLTGLFALLATGATTP
MAB_1379c|M.abscessus_ATCC_199 AAIQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAF
: . . .. : . ::
Mb0068c|M.bovis_AF2122/97 ----AKVTDVALDGLRANRK-----
Rv0067c|M.tuberculosis_H37Rv ----AKVTDVALDGLRANRK-----
MAV_2459|M.avium_104 -TGHALLEDYVARTLRSLKP-----
MSMEG_6604|M.smegmatis_MC2_155 -TRDEVLDDYVRRTLRSMRP-----
Mflv_4907|M.gilvum_PYR-GCK -GRSVLVTDYLTRTLRSLQ------
Mvan_1513|M.vanbaalenii_PYR-1 -GRRELVDDYLTRTLRSLQ------
TH_1661|M.thermoresistible__bu -NRAGMVDDFVANTLRSLRPRLTRR
MMAR_0249|M.marinum_M DARTALLNRFVTTVVHGMEAR----
MUL_4864|M.ulcerans_Agy99 DARTALLNGFVTTVVHGMEAR----
MAB_1379c|M.abscessus_ATCC_199 EQLAHAVREILYYGLASDHHPQIAD
: : . .