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ADGITAREAKRLQTRERLLGAAIAEFKRAGKDESDVGAIVAAAGVAHGTFFFHFPTKEHVLLELERREED RMAKRFATFTKTHHDLASALREAAHLVMGLERRLGVVLFKDFLALHFSPTRPPAEHGDDHPLVVLVADQI DNARQRGDTAADVTPMNSAIYFLLGLYALLITTDDSTGRRELVDDYLTRTLRSLQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1513 | - | - | 100% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4973 | - | 1e-54 | 54.97% (191) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0989 | - | 4e-07 | 48.21% (56) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 8e-05 | 32.88% (73) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_4907 | - | 1e-95 | 88.27% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 8e-05 | 32.88% (73) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1379c | - | 2e-06 | 27.12% (118) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 3e-38 | 44.21% (190) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2459 | - | 4e-77 | 72.96% (196) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 7e-77 | 70.77% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1661 | - | 1e-72 | 68.21% (195) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 3e-39 | 44.74% (190) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3605|M.bovis_AF2122/97 -------MAVLAESELGSEAQRER-RKRILDATMAIASKGGYEAVQMRAV
Rv3574|M.tuberculosis_H37Rv -------MAVLAESELGSEAQRER-RKRILDATMAIASKGGYEAVQMRAV
Mvan_1513|M.vanbaalenii_PYR-1 ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGKDESDVGAI
Mflv_4907|M.gilvum_PYR-GCK ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGMAEADVSTI
MAV_2459|M.avium_104 ----------MADRLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGAI
MSMEG_6604|M.smegmatis_MC2_155 --------MAGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADADVGTI
TH_1661|M.thermoresistible__bu --------MARAEKPSAREAKRLQTRERLLGAAIAEFKRTGMAEADVRAI
MMAR_0249|M.marinum_M MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MUL_4864|M.ulcerans_Agy99 MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MAB_1379c|M.abscessus_ATCC_199 ----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIADI
. * :: . * .::.*::* . * : :
Mb3605|M.bovis_AF2122/97 ADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQR
Rv3574|M.tuberculosis_H37Rv ADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQR
Mvan_1513|M.vanbaalenii_PYR-1 VAAAGVAHGTFFFHFPTKEHVLLELERREEDRMAKRFATFTKTHHDLASA
Mflv_4907|M.gilvum_PYR-GCK VGAAGVAHGTFFFHFPTKEHVLLELERREEDRIAKRFATFTKTHHDLSAV
MAV_2459|M.avium_104 VAAAGVAHGTFFFHFPTKEHVLLELERREEERIAKQFAQFLKSEHDLASA
MSMEG_6604|M.smegmatis_MC2_155 VAAAGVAHGTFFFHFPTKEHVLLELEQREEERIAKQFAQFVKKPHDLEAA
TH_1661|M.thermoresistible__bu VAAAGVAHGTFFFHFPTKEHVLLELERREEERIARQFSRFLETEHDLVGT
MMAR_0249|M.marinum_M AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADPTDLVSV
MUL_4864|M.ulcerans_Agy99 AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADSTDLVSV
MAB_1379c|M.abscessus_ATCC_199 VRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAPTSLAE
. ..:* **:: :* :* .:: . :
Mb3605|M.bovis_AF2122/97 LNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFAR
Rv3574|M.tuberculosis_H37Rv LNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFAR
Mvan_1513|M.vanbaalenii_PYR-1 LREAAHLVMGLERRLGVVLFKDFLALHFSPTRPPAEHGDDHPLVVLVADQ
Mflv_4907|M.gilvum_PYR-GCK LREAADLVLGLERRLGVVLFKDFLALHFSPTRPPAEHGGDHPVVVLVAAQ
MAV_2459|M.avium_104 LNEAVRLVVGLERRLGDMLFNDFLALHFSQTRPQTEDGRDHPLIVLVANE
MSMEG_6604|M.smegmatis_MC2_155 LREIVRLVIGLERRLGDLLFKDFLALHFSQTRPRVDEGMEHPVIARVTEE
TH_1661|M.thermoresistible__bu LKEAVRLVLDIEDRLGPVLFKDFLALHFSPTRPPAEEGQDHPLIVSVAEE
MMAR_0249|M.marinum_M LSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIET
MUL_4864|M.ulcerans_Agy99 LSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIET
MAB_1379c|M.abscessus_ATCC_199 YRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAAA
. : : : :
Mb3605|M.bovis_AF2122/97 AMANGEPTEDQY----------HIARVISDVWLSN-LLAWLTRRASAT-D
Rv3574|M.tuberculosis_H37Rv AMANGEPTEDQY----------HIARVISDVWLSN-LLAWLTRRASAT-D
Mvan_1513|M.vanbaalenii_PYR-1 IDNARQRGDTAA----------DVTPMNSAIYFLLGLYALLITTDDST-G
Mflv_4907|M.gilvum_PYR-GCK IEHARQRGETAA----------DVTPMNSAIYFLLGLYALLVTTDEST-G
MAV_2459|M.avium_104 IEGAQQRGETDP----------HVNPMNSAVFFLLGLYALLITTNHWP-T
MSMEG_6604|M.smegmatis_MC2_155 IEAARQRGDVAA----------DVNPVNSAVFFLLGFYALLVTTNDWP-T
TH_1661|M.thermoresistible__bu IERAQRAGEVDA----------EVNPWNSAVFFLLGLYALLTTTHAWP-N
MMAR_0249|M.marinum_M IARAQRANRVPP----------DADAGELGVIFLTGLFALLATGATTPDA
MUL_4864|M.ulcerans_Agy99 IAQAQRADRVAP----------DADAGELGVIFLTGLFALLATGATTPDA
MAB_1379c|M.abscessus_ATCC_199 IQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAFEQ
. : : : :
Mb3605|M.bovis_AF2122/97 VSKRLDLAVRLLIGDQDSA----
Rv3574|M.tuberculosis_H37Rv VSKRLDLAVRLLIGDQDSA----
Mvan_1513|M.vanbaalenii_PYR-1 RRELVDDYLTRTLRSLQ------
Mflv_4907|M.gilvum_PYR-GCK RSVLVTDYLTRTLRSLQ------
MAV_2459|M.avium_104 GHALLEDYVARTLRSLKP-----
MSMEG_6604|M.smegmatis_MC2_155 RDEVLDDYVRRTLRSMRP-----
TH_1661|M.thermoresistible__bu RAGMVDDFVANTLRSLRPRLTRR
MMAR_0249|M.marinum_M RTALLNRFVTTVVHGMEAR----
MUL_4864|M.ulcerans_Agy99 RTALLNGFVTTVVHGMEAR----
MAB_1379c|M.abscessus_ATCC_199 LAHAVREILYYGLASDHHPQIAD
: : : .