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PEQLSRFERRKQETRREILGAALACFAERGYHATGIADIVRRVGIAQGTFYLYFQSKREIVEQILDDLME RLSAALLDLPPSAPTSLAEYRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAAAI QATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAFEQLAHAVREILYYGLASDHHPQI AD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1379c | - | - | 100% (213) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1525c | - | 1e-41 | 40.89% (203) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4946 | - | 3e-28 | 34.36% (195) | putative transcriptional regulator, TetR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 6e-11 | 27.36% (212) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3637 | - | 2e-12 | 30.68% (176) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 7e-11 | 27.36% (212) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 7e-07 | 31.25% (80) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_5046 | - | 1e-11 | 28.93% (159) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0603 | - | 2e-11 | 27.18% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 3e-10 | 26.90% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4015 | - | 2e-10 | 28.64% (206) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4120 | - | 2e-10 | 29.86% (144) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5283 | - | 6e-10 | 25.96% (208) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3587c|M.bovis_AF2122/97 ----------------------------MDRVAGQVNSRRGELLELAAAM
Rv3557c|M.tuberculosis_H37Rv ----------------------------MDRVAGQVNSRRGELLELAAAM
MMAR_5046|M.marinum_M ----------------------------MERMTGQANSRRGELLGLAAVM
MUL_4120|M.ulcerans_Agy99 -------------------------------------------MGLAAVM
MAV_0603|M.avium_104 -------------------------------MTGPANSRRDELLELAAAM
Mvan_5283|M.vanbaalenii_PYR-1 ---------------------------MSSGQAPQANTRRDELLQLAATM
MSMEG_6009|M.smegmatis_MC2_155 ---------------------------MAPDTPSQPASRRDELLQLAATM
MAB_1379c|M.abscessus_ATCC_199 ------------------------MPEQLSRFERRKQETRREILGAALAC
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
Mflv_3637|M.gilvum_PYR-GCK --------------MENETLSVSAGRKRGRPVAADSEQTRRTVLAAARDI
MLBr_00717|M.leprae_Br4923 --------------------------MTTARRRLSPEDRRAELLALGAEV
: .
Mb3587c|M.bovis_AF2122/97 FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFAR
Rv3557c|M.tuberculosis_H37Rv FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFAR
MMAR_5046|M.marinum_M FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLDWLFAR
MUL_4120|M.ulcerans_Agy99 FAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLDWLFAR
MAV_0603|M.avium_104 FAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLDWLFAR
Mvan_5283|M.vanbaalenii_PYR-1 FAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRGFLDWLFDR
MSMEG_6009|M.smegmatis_MC2_155 FADRGLKATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLRDFLDWLFGR
MAB_1379c|M.abscessus_ATCC_199 FAERGYHATGIADIVRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAA
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQP
Mflv_3637|M.gilvum_PYR-GCK IAERGYQATTFQQIAQRAGVSRPTLHYYFATREDLYDALLADVCERLGRC
MLBr_00717|M.leprae_Br4923 FGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAA
:. . . :*. .* :: :* :. : :: : *
Mb3587c|M.bovis_AF2122/97 YRDIVDSTA-NPLERLQG---LFMASFEAIEHHHAQVVIYQDEAQR----
Rv3557c|M.tuberculosis_H37Rv YRDIVDSTA-NPLERLQG---LFMASFEAIEHHHAQVVIYQDEAQR----
MMAR_5046|M.marinum_M YLEIVDGEP-NPLERLKG---LFLASFEAIEHRHAQVVIYQDEAQR----
MUL_4120|M.ulcerans_Agy99 YLEIVDGEP-NPLERLKG---LFLASFEAIEHRHAQVVIYQDEAQR----
MAV_0603|M.avium_104 YREIIDSES-NPLERLKG---LFMASFEAIEHRHAQVVIYQDEAKR----
Mvan_5283|M.vanbaalenii_PYR-1 YQQIVATEP-NPLERLKG---LFMASFEAIETRHAEVVIYQDEAKR----
MSMEG_6009|M.smegmatis_MC2_155 YQQILDTAT-SPLEKLTG---LFMASFEAIEHRHAQVVIYQDEAKR----
MAB_1379c|M.abscessus_ATCC_199 LLDLPPSAP-TSLAEYRDQAEHISTSLTGVLSADPQAARFLLLQAA----
TH_4015|M.thermoresistible__bu VRTDAGTEPKNPYERILR---ANRTYLEAYRANRAIMIVWEQVASLNE--
Mflv_3637|M.gilvum_PYR-GCK AAAAAGQDS------LRGQLAAFMAEMNRLAVAEPAMMKLVVTARIDHHG
MLBr_00717|M.leprae_Br4923 T-NIPPPAGLTMFEEVRVG--VLAYMAYHKQNPEAAWAAYVGLGRSDPVL
.
Mb3587c|M.bovis_AF2122/97 --LASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIR
Rv3557c|M.tuberculosis_H37Rv --LASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIR
MMAR_5046|M.marinum_M --LSSQPRFSYLEDRNKEQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIR
MUL_4120|M.ulcerans_Agy99 --LSSQPRFSYLEDRNKEQRKMWLDVLNQGIEEGYFRPDLDVDLVYRFIR
MAV_0603|M.avium_104 --LLSQPRFSYIEDMNRQQRKMWLEVLNQGVDEGYFRPDLDVDLVYRFIR
Mvan_5283|M.vanbaalenii_PYR-1 --LSAQGRFAYVEERNKEQRKMWVDVLTQGIDEGYFRPDVDVDLVYRFIR
MSMEG_6009|M.smegmatis_MC2_155 --LSDLPQFDFVETRNKEQRKMWVDILQEGVADGSFRPDLDVDLVYRFIR
MAB_1379c|M.abscessus_ATCC_199 --AVDDDMAERVLAFYDAAAAIQATYLQHGISAGYFRSDLDAGHAARAVN
TH_4015|M.thermoresistible__bu --HVEQLRREYSDRFAARIERAIIRWQEAGLADPAIDPRYAAAALSGMLS
Mflv_3637|M.gilvum_PYR-GCK ARIGTGEGRGAATDIVSTVHDFYDAVVLAAAARGELPAGHDPHAVADMLA
MLBr_00717|M.leprae_Br4923 LGIDDEAKNRQMEHIMSRIGDVVSVVPESKLHP---DIERDLRVIVHGWL
Mb3587c|M.bovis_AF2122/97 DTTWVS---VRWYRPG-GPLTAQQVGQQYLAIVLGG--ITKEGV------
Rv3557c|M.tuberculosis_H37Rv DTTWVS---VRWYRPG-GPLTAQQVGQQYLAIVLGG--ITKEGV------
MMAR_5046|M.marinum_M DTTWVS---VRWYKPG-GALTAQQVGQKYLAIVLGG--IQKEGV------
MUL_4120|M.ulcerans_Agy99 DTTWVS---VRWYKPG-GALTAQQVGQKYLAIVLGG--IQKEGV------
MAV_0603|M.avium_104 DTTWVS---VRWYQPG-GPLTAEQVGQQYLAIVLGG--ITVDAKKD----
Mvan_5283|M.vanbaalenii_PYR-1 DTTWVS---VRWYQPG-GPLTAQQVGRQYLSIVLGG--ITAEPTSKESTN
MSMEG_6009|M.smegmatis_MC2_155 DTTWVS---VRWYKPG-GPLSAEQVGQQYLAIVLGG--ITQSQGDKHA--
MAB_1379c|M.abscessus_ATCC_199 GMLLAS---AFYSLRDPSPAAFEQLAHAVREILYYG--LASDHHPQIAD-
TH_4015|M.thermoresistible__bu NFAYRW---SVQDADYDLDTAAEQLSLLWANALGVR--VPAHHEPAHA--
Mflv_3637|M.gilvum_PYR-GCK AVFWGLGFHARMLTADIGVDGVPEVARQLLSVLDSG--LLDGALRAPADA
MLBr_00717|M.leprae_Br4923 AFTFEVCRQRIMDPSTDADRLADSCAHALLDAIARVPEISKELADAMAIA
. . : :
Mb3587c|M.bovis_AF2122/97 -----
Rv3557c|M.tuberculosis_H37Rv -----
MMAR_5046|M.marinum_M -----
MUL_4120|M.ulcerans_Agy99 -----
MAV_0603|M.avium_104 -----
Mvan_5283|M.vanbaalenii_PYR-1 G----
MSMEG_6009|M.smegmatis_MC2_155 -----
MAB_1379c|M.abscessus_ATCC_199 -----
TH_4015|M.thermoresistible__bu -----
Mflv_3637|M.gilvum_PYR-GCK -----
MLBr_00717|M.leprae_Br4923 RQPPQ