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MTDQPKRRRRRADGELSRRRILDAATEIAAERGYEGTSIGAVSAKCGLPASSIYWHFKDKDDLIAAVIER SFANWLTVWQLPDDVMARDRLMEVAMGTAKAVLDSPDFLRLGLMLALERRPVEPKARAMFIQVREQAFAA LATSIRDLGLDLSEEQVRHLSTYAIAGADGLFIAKEIGGDTVDLMALFALHGQALYDTALRMIEENNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0594 | - | - | 100% (208) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3432 | - | 8e-09 | 25.28% (178) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1989 | - | 2e-08 | 25.74% (136) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 2e-21 | 32.20% (205) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4599 | - | 3e-09 | 46.77% (62) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 2e-21 | 32.20% (205) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-05 | 27.14% (70) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 2e-09 | 32.43% (111) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1504 | - | 7e-73 | 67.16% (204) | transcriptional regulatory protein |
| M. avium 104 | MAV_3803 | - | 1e-10 | 43.66% (71) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1500 | - | 7e-12 | 31.69% (183) | TetR family protein transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_2719 | - | 2e-09 | 27.32% (183) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2448 | - | 2e-09 | 25.15% (163) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0594|M.vanbaalenii_PYR-1 --------------------MTDQPKR---RRRRADGELSRRRILDAATE
MMAR_1504|M.marinum_M ----------------MAKETESRPRKRAPRRGRADGELSRARILDAATE
Mb0310|M.bovis_AF2122/97 ---------------------MGVPAK----KKQQQGERSRESILDATER
Rv0302|M.tuberculosis_H37Rv ---------------------MGVPAK----KKQQQGERSRESILDATER
Mflv_4599|M.gilvum_PYR-GCK --------------------MNKVVVAG---RTRVGGER-RERILASATE
TH_2719|M.thermoresistible__bu --------------------MAS--------RRAQISEESRRLLIAAATE
MAB_1149|M.abscessus_ATCC_1997 -----------------MAVPSRPDVPGRTPRVRMAGSERRRQLIDVARS
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MUL_2448|M.ulcerans_Agy99 -------------------MPARQESR----ELSSKGRQTRQAIEQVARK
MSMEG_1500|M.smegmatis_MC2_155 --------------------MTGPG------RGRPRDAAADRAILHAALD
MAV_3803|M.avium_104 ---------------MSAPTAAPRDRVRHPRRPADSVLVRREAILDAAWA
: :
Mvan_0594|M.vanbaalenii_PYR-1 IAAERGYEGTSIGAVSAKCGLPASSIYWHFKDKDDLIAAVIERSFANWLT
MMAR_1504|M.marinum_M IAAERGYEGTSIALVSAKCGLPASSIYWHFKDKDDLIAAVIERSFGGWLT
Mb0310|M.bovis_AF2122/97 LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Rv0302|M.tuberculosis_H37Rv LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Mflv_4599|M.gilvum_PYR-GCK LIAERGYHAVSMADIGVASGVVGPAIYRHFNSKSDLLAALFERVVDKLLK
TH_2719|M.thermoresistible__bu LFAEQGFRRTTFADIAERSGISRGSIPWHFGNKDGLLRAVIEDFIAGVIE
MAB_1149|M.abscessus_ATCC_1997 LFAERGYEATSIEEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMSVLLD
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MUL_2448|M.ulcerans_Agy99 LFAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVT
MSMEG_1500|M.smegmatis_MC2_155 LFIERGVEGTSIEQIARRAGVGKPTIYRRWSTKEDLIAAAMETLVAEEVV
MAV_3803|M.avium_104 VASAQGFDGVQMRAVAAQAGIAASSLYRHFRSKSHLLVTVLAREFERLDT
: :* . : : .* . : * : .
Mvan_0594|M.vanbaalenii_PYR-1 VWQLP------DDVMARDRLMEVAMGTAKAVLDSPDFLRLGLMLALERRP
MMAR_1504|M.marinum_M AWQIPEGQSGDETIQGAEQFVGLATQTAKALLDSPDFIRLGLMLALERRP
Mb0310|M.bovis_AF2122/97 AIPTWDEAHGPVEQRSERQLTELVSLQS----QHPDFLRLFYLLSMER-S
Rv0302|M.tuberculosis_H37Rv AIPTWDEAHGPVEQRSERQLTELVSLQS----QHPDFLRLFYLLSMER-S
Mflv_4599|M.gilvum_PYR-GCK RATAIVEQSRDEAEALTLLVSDQVALVMDQRELAMVYYREVHNLSDQHQS
TH_2719|M.thermoresistible__bu LDASEQTLS-----EGLDRIRDYVRRPT---------TRLLITLVAEAVE
MAB_1149|M.abscessus_ATCC_1997 GITSSLTSY-----RSRVRLEQVALALLSYIEERTDGFRILIRDSPPGVS
MLBr_00815|M.leprae_Br4923 SVQQALRTT----TNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEP
MUL_2448|M.ulcerans_Agy99 PSGVSLQLP---DSPDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQ
MSMEG_1500|M.smegmatis_MC2_155 WASPEEIES-----RSPHVLVEAAIESAAATTASPSYRALVARVYGSAVS
MAV_3803|M.avium_104 EFDCTTGELAP-QARLGRLTTHLHMAWQANPHLTEAMVRAFVVADSEAAG
Mvan_0594|M.vanbaalenii_PYR-1 VEPKARAMFIQVREQAFAALATSIRDLG-----LDLSEEQVRHLSTYAIA
MMAR_1504|M.marinum_M AEPRARTMFLEVRAQAFGQLIGNFGRFM-----PGLTEAQIYQLATYAMA
Mb0310|M.bovis_AF2122/97 QDPVVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVA
Rv0302|M.tuberculosis_H37Rv QDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVA
Mflv_4599|M.gilvum_PYR-GCK RLRRKQRLYLEEWVHLVGELRPAVDEIELRAMVHGAIGAIQSILHYRGTG
TH_2719|M.thermoresistible__bu PDSPVHAFYAQLHDTLRKWLSDWIDDKD---IPPGVSRE---NFVTVLIG
MAB_1149|M.abscessus_ATCC_1997 SGTYS-SLLNDAVSQVSSILAGDFQRRG--------LDAEMAPLYAQALV
MLBr_00815|M.leprae_Br4923 RVAAQVRVATESCIDAVFALISADSRLD----------PHRARMVAVGLV
MUL_2448|M.ulcerans_Agy99 RFAAVQNQFRRFGMDIIAASVRHAQDQG-------YGTELNPDHTAVAIA
MSMEG_1500|M.smegmatis_MC2_155 HPGLMAVYWDRYILPRRAQARRLLERAR------ELGTVSEDTDLDVAID
MAV_3803|M.avium_104 AIEHAVAVIEDMLARALGGPTPSAHDRD--------VASLIADVWLANLI
Mvan_0594|M.vanbaalenii_PYR-1 GADGLFIAKEIGGDT-VDLMALFALHGQALYDTALRMIEENNR---
MMAR_1504|M.marinum_M GADGLFIAKEIDGDA-VNLIEMFELHGRALYDAARRFIEDGATR--
Mb0310|M.bovis_AF2122/97 LSDGVYFAGHLEPDT-TDVERMYRRLRQALEALIPVLLEET-----
Rv0302|M.tuberculosis_H37Rv LSDGVYFAGHLEPDT-TDVERMYRRLRQALEALIPVLLEET-----
Mflv_4599|M.gilvum_PYR-GCK LAPEQTSALLVAMGH-AVLGVPASSHQVRGVNTEPSCPRPGTPQH-
TH_2719|M.thermoresistible__bu AVIGVHQQWRVAPHH-VDLDACFAALKQLASGD-------------
MAB_1149|M.abscessus_ATCC_1997 GQVSMTAQWWLDARE-PKKEVVAAHIVNLCWHGLKHLEADPQLHEE
MLBr_00815|M.leprae_Br4923 GISVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----
MUL_2448|M.ulcerans_Agy99 LLFENFTSVLVGTSGSSGPGGLGVTITDEDAITTLSRIWKKTLYGF
MSMEG_1500|M.smegmatis_MC2_155 MMVGAITYRVLQPDP-PDVDGMRRYLRAVYRQIGLLS---------
MAV_3803|M.avium_104 AVIGGRIDADLARER------IDRTTRQLVHGTDTTT---------
: