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SDPALESTRRRLTARQADTVDRLGRAAVELLRRDGFAALTVRRVAAEAGVGAATAYTYFSSKEHLVAEVF WRRLAGSQRVDHGSGDPASRVVEVLGHISLLVAGEPEFAGAVTTALLGKDPDVEVLRLRIGRDIRDRLSD ALGPDTDPDVIDALEMLYSGALVRAGMGYTSYPEIAAKLEKAARLMLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5714 | - | - | 100% (189) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5158 | - | 2e-33 | 45.14% (175) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4585 | - | 3e-13 | 29.87% (154) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0790c | - | 2e-32 | 44.44% (189) | hypothetical protein Mb0790c |
| M. gilvum PYR-GCK | Mflv_1599 | - | 3e-33 | 45.14% (175) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0767c | - | 2e-32 | 44.44% (189) | hypothetical protein Rv0767c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1217c | - | 3e-33 | 43.85% (187) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4929 | - | 3e-34 | 46.52% (187) | hypothetical protein MMAR_4929 |
| M. avium 104 | MAV_0711 | - | 3e-36 | 46.03% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6479 | - | 1e-73 | 73.94% (188) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_0084 | - | 2e-79 | 79.26% (188) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3114 | - | 3e-26 | 43.04% (158) | hypothetical protein MUL_3114 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1599|M.gilvum_PYR-GCK MSSDAVAALTPESGHP------PRNRRQEETFRKVLAAGLEMLRESSYAD
MAB_1217c|M.abscessus_ATCC_199 MSSEVVVPLTEET---------PRNRRQEETIRKIVTAGREMLGETTYAD
Mb0790c|M.bovis_AF2122/97 MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
Rv0767c|M.tuberculosis_H37Rv MSSDVLVTTPAQRQTEPHAEAVSRNRRQQATFRKVLAAAMATLREKSYAD
MMAR_4929|M.marinum_M MSSDALVTVTDQQQHE--SGDRRRNRRQEETFRRVLAAGMDTLRASSYPD
MAV_0711|M.avium_104 MSSDALVTITSDAGGE--TGQPPRNRRQEETFRKVLAAGIETLREKSYSD
MUL_3114|M.ulcerans_Agy99 ---------------------------------------MDELRATSFAN
MSMEG_6479|M.smegmatis_MC2_155 MSDPAMESTRRR-----------LSARQADTVERLGRAAVELISREGYAG
TH_0084|M.thermoresistible__bu VSDPALESTRRR-----------LTAKQADTVDRLGRAAVELLQREGFAG
Mvan_5714|M.vanbaalenii_PYR-1 MSDPALESTRRR-----------LTARQADTVDRLGRAAVELLRRDGFAA
: :.
Mflv_1599|M.gilvum_PYR-GCK LTVRAVAARAKVAPATAYTYFSSKNHLIAEIYLNLMQQVDYFTDVNDSTV
MAB_1217c|M.abscessus_ATCC_199 MTIRGVAARAKVAPATAYTYFSSKSHLVAEIYLDLIHEAPYFTDVNDTQA
Mb0790c|M.bovis_AF2122/97 LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
Rv0767c|M.tuberculosis_H37Rv LTVRLVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPCVTDVNVPMP
MMAR_4929|M.marinum_M LTVRMVAARAGVSPATAYTYFSSKNHLIAEVYLDLVRKVPFFTDVNVAMR
MAV_0711|M.avium_104 LTVRAVAARAKVAPATAYTYFSSKNHLIAEVYLDLVRQVPYFTDVNDPMP
MUL_3114|M.ulcerans_Agy99 LTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLLRDLPLHTDVNDTTK
MSMEG_6479|M.smegmatis_MC2_155 LTVRRVAAEAGVGSATAYTYFSSKEHLVAEVFWRRLSAAPPAVHESPDPA
TH_0084|M.thermoresistible__bu LTIRRVAAEAGVGAATAYTYFSSKEHLVAEVFWRRLAAAPPADHKSDDPA
Mvan_5714|M.vanbaalenii_PYR-1 LTVRRVAAEAGVGAATAYTYFSSKEHLVAEVFWRRLAGSQRVDHGSGDPA
:*:* ***.* *..*:*****.**. *:* :: : . .
Mflv_1599|M.gilvum_PYR-GCK TRVEKTLRSMALMVADEPEVAAACTTALLSG-NDATVRSVRERIGGEIHR
MAB_1217c|M.abscessus_ATCC_199 ARVTKTLRSLALVVADEPEIATGCTTALLSN-NDEAVRAVRDKIGLEIHR
Mb0790c|M.bovis_AF2122/97 IRVTSSLRHLALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEIHR
Rv0767c|M.tuberculosis_H37Rv IRVTSSLRHLALVVADEPEIGAACTAALLDGGADPAVRAVRDRIGAEIHR
MMAR_4929|M.marinum_M DRVVQALRHLALVVADEPEVGAACTAALLGGGADPAVRAVRDQIGAEIHR
MAV_0711|M.avium_104 TRVEQVLRHLALVVADEPEVSAACTTALLSGGADPAVRAARDRIGVEIHR
MUL_3114|M.ulcerans_Agy99 TRVSATMRDMAMVVADEPELTAACGTALMAD--DPAVQPLRTQIGEEVAR
MSMEG_6479|M.smegmatis_MC2_155 TRVVEVLQHIASLVADEPAFAGAVTTALLGK--DPDVDALRQRIGADIRQ
TH_0084|M.thermoresistible__bu TRVIEVLRHIALLVADEPEFAGAVTTALLGR--DPDVEVLRQRIGRDIRD
Mvan_5714|M.vanbaalenii_PYR-1 SRVVEVLGHISLLVAGEPEFAGAVTTALLGK--DPDVEVLRLRIGRDIRD
** : :: :**.** . . :**: * * * :** ::
Mflv_1599|M.gilvum_PYR-GCK RIRAAVGPDPDPRTLAALEMTFFGALVNAGSGAFTYHQIADRLSYVVGLI
MAB_1217c|M.abscessus_ATCC_199 RIRSAMGPDADPRVVSALEMTFFGALMHAGSGTFTYHQIADKLTFVVDLM
Mb0790c|M.bovis_AF2122/97 RITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADRLGYVVGLI
Rv0767c|M.tuberculosis_H37Rv RITSAIGPGADPGTVFALEMAFFGALVQAGSGTFTYHEIADRLGYVVGLI
MMAR_4929|M.marinum_M RIASAIGPGAQPGTIAALEMAFFGALVHAGSGEFTYHEVADRLADVAVLI
MAV_0711|M.avium_104 RITSAMGPDADPTTVSALEMSFFGALVQAGSGEFSYREIADRLAYVVRLI
MUL_3114|M.ulcerans_Agy99 RIGAALGPGWPRSVKSTLQMTFSGALMTAR--FLSYEEIAGQLDEAVNLI
MSMEG_6479|M.smegmatis_MC2_155 RLVAALGPDVRIDVIEALELLYTGTMVWAGMGYDSYEQVVRRLEKSARLV
TH_0084|M.thermoresistible__bu RLLAALGPQTDYDVIEALELLYIGVLVWVGMGYSSQEDMTRRLEKSARLI
Mvan_5714|M.vanbaalenii_PYR-1 RLSDALGPDTDPDVIDALEMLYSGALVRAGMGYTSYPEIAAKLEKAARLM
*: *:** . :*:: : *.:: . : ::. :* . *:
Mflv_1599|M.gilvum_PYR-GCK VGDDQ-------------------
MAB_1217c|M.abscessus_ATCC_199 LGKKE-------------------
Mb0790c|M.bovis_AF2122/97 LAGANEPSTG----------GSE-
Rv0767c|M.tuberculosis_H37Rv LAGANEPSTG----------GSE-
MMAR_4929|M.marinum_M LVGAGQAAPGDDLAEPAAEAGEDA
MAV_0711|M.avium_104 LTGTTQASPET-------EAGDTR
MUL_3114|M.ulcerans_Agy99 LGAAVA------------------
MSMEG_6479|M.smegmatis_MC2_155 LS----------------------
TH_0084|M.thermoresistible__bu LR----------------------
Mvan_5714|M.vanbaalenii_PYR-1 LG----------------------
: