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MDGVTELEKGPRGRRRGRGARERILGAAQQLFRERGINNTGMDLLCAAAQVSKRTAYQHFGSKDELIAEY LRRLDVDTTSEVFERDDLTPRERLLAVFATPPAFTDEPMPLCPFIAAAVEISDPQHPARVRAREYKTSVA ARLSETAREAGAADPELLGEQLALLLDGASVRTRALGSDAFPTAAGIAAALVERAIPPTAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1243 | - | - | 100% (201) | transcriptional regulator |
| M. avium 104 | MAV_2097 | - | 7e-33 | 47.03% (185) | transcriptional regulator |
| M. avium 104 | MAV_3517 | - | 5e-17 | 31.96% (194) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3198c | - | 1e-30 | 45.36% (194) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5008 | - | 1e-08 | 32.03% (153) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3173c | - | 2e-30 | 45.36% (194) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 7e-07 | 40.98% (61) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2458c | - | 4e-13 | 33.54% (158) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2062 | - | 2e-14 | 32.04% (181) | hypothetical protein MMAR_2062 |
| M. smegmatis MC2 155 | MSMEG_6503 | - | 9e-32 | 44.94% (178) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3775 | - | 7e-17 | 35.39% (178) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_1163 | - | 3e-07 | 42.62% (61) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | 3e-20 | 35.84% (173) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3198c|M.bovis_AF2122/97 -MPPVTRTTEPPRRG--GRGARQRILKAAAELFYCEGINATGVELIANKA
Rv3173c|M.tuberculosis_H37Rv -MPPVTRTTEPPRRG--GRGARQRILKAAAELFYCEGINATGVELIANKA
MSMEG_6503|M.smegmatis_MC2_155 ----MTK----PR----GRGGRERIVAAAAALFEAQGITATTMEQIAAKA
MAV_1243|M.avium_104 -MDGVTELEKGPRGRRRGRGARERILGAAQQLFRERGINNTGMDLLCAAA
Mvan_4792|M.vanbaalenii_PYR-1 -MP--------------AEDPRQRAIDAAVELFHREGFGAVGIDRLTTSI
TH_3775|M.thermoresistible__bu ---------------MAETDDKNRVLATATTLFNERGVQAVGMDAIRDAA
MLBr_02568|M.leprae_Br4923 --------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEA
MUL_1163|M.ulcerans_Agy99 --------MAGGTKRLPRAIREQQMLDAAVQMFSANGYHETSMDTIAAAA
MAB_2458c|M.abscessus_ATCC_199 MSSATVPTAADSARTARVLGPADRLLQTATDLFATQGIRSVGIDQILREA
MMAR_2062|M.marinum_M --------MAIPEATTAAVPARERILGAAYDLFSRRGIRAVGTDEVIERA
Mflv_5008|M.gilvum_PYR-GCK -------MTAPVRGRPRDPDADRAILQAALDLFIERGVEGSSIEQIAKRA
: :* :* .* : :
Mb3198c|M.bovis_AF2122/97 SVSKRTLYQHFPSKSALVEEYLRGLRQAAGE-ADKMPKASNAT-PRERLL
Rv3173c|M.tuberculosis_H37Rv SVSKRTLYQHFPSKSALVEEYLRGLRQAAGE-ADKMPKASNAT-PRERLL
MSMEG_6503|M.smegmatis_MC2_155 PVSKRTLYAHFPTKDDLVVEFLQYVYRSGLT-VESALYDADVP-ARERIL
MAV_1243|M.avium_104 QVSKRTAYQHFGSKDELIAEYLR--RLDVDT-TSEVFERDDLT-PRERLL
Mvan_4792|M.vanbaalenii_PYR-1 GMSKRTLYKYFDSKDDLLLAVLDS-CEGMAL-RDLPDEDDDSS-PRDRIL
TH_3775|M.thermoresistible__bu GISLKRLYSCFRSKADLVAAVLEQRDADVRR-AMTEYVQSRAADPRDRIL
MLBr_02568|M.leprae_Br4923 QISKPMLYLYYGSKEDLFGACLNREMSRFIA-MVRADIDFTQS-PKDLLR
MUL_1163|M.ulcerans_Agy99 QISKPMLYLYYGSKEDLFGACLNREMSRFID-AVRADIDLSQS-PKDLLR
MAB_2458c|M.abscessus_ATCC_199 GVAKASLYSSFGSKDALVVAYLEELDQRDRN-RWNAAVAAQRD-PIAKVL
MMAR_2062|M.marinum_M GVARATLYRHFATKDDLVLAVLQRREELWTFGLIEQKSRARGNTPEEQLL
Mflv_5008|M.gilvum_PYR-GCK GVGKPTVYRRWGTKEELIAAAMETLVAEEVG--WTSPEAIETRSPHVLVE
:. * : :* *. : . :
Mb3198c|M.bovis_AF2122/97 ALFDRP-NRGDGR---MRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIKG
Rv3173c|M.tuberculosis_H37Rv ALFDRP-NRGDGR---MRGCPFHNAAVEAAGEMPGVERIVHSHKRDYIKG
MSMEG_6503|M.smegmatis_MC2_155 AMFTVP-TRGDGP---VRGCPFVAAATEFPDPDSPAHAYTRERKQAFTLR
MAV_1243|M.avium_104 AVFATPPAFTDEP---MPLCPFIAAAVEISDPQHPARVRAREYKTSVAAR
Mvan_4792|M.vanbaalenii_PYR-1 AVFDAQAKYCTDPD--FAGCFFVNIATEFRDPDHRAVRIAADHKAKLTQF
TH_3775|M.thermoresistible__bu AVFDFLAHWFAESD--FRGCMFINTIGELGGTSTDVRRIARLHKTAVRDY
MLBr_02568|M.leprae_Br4923 NTIVSFLRYIDAN---RASWIVMYIQAMSLPAFAQTVREARDQITELVAG
MUL_1163|M.ulcerans_Agy99 NAIVSFLRYIDQN---QASWIVMYTQAVSSQAFAQTVREGREQIVELVAG
MAB_2458c|M.abscessus_ATCC_199 TFFDLAATAAESRN--FRGCLYANAATEFPGLQLEPVR---THREWFRAT
MMAR_2062|M.marinum_M AIFDVLHEWFQSRDG-YEGCSFINVLLELG-ADHPAGRACIGHIDHVRGI
Mflv_5008|M.gilvum_PYR-GCK AAIDSAAAATAAPYYRALVARVYGSAVSHPELMTVYWDRYILPRRVQATR
:
Mb3198c|M.bovis_AF2122/97 LARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVL
Rv3173c|M.tuberculosis_H37Rv LARLAREAGAAHPRSLGNQLAVLFEGAAALSTSLDDAGPWAHARAAAEVL
MSMEG_6503|M.smegmatis_MC2_155 IAELLTELGADDPHGLAEQLAILTDGVASRSMVFNDARRGDVGRAAAEAL
MAV_1243|M.avium_104 LSETAREAGAADPELLGEQLALLLDGASVRTRALG-SDAFPTAAGIAAAL
Mvan_4792|M.vanbaalenii_PYR-1 LVRQARLAGVAAPDDLAEQLTVLHTGAADYALLYG--HYPDSTRTAVAAL
TH_3775|M.thermoresistible__bu LADLV--AAAELPSELAEQLAILADGAIVAATIWGDGTDAAAAARRAAAT
MLBr_02568|M.leprae_Br4923 LMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINL
MUL_1163|M.ulcerans_Agy99 MLRAGTRSPRSDAEIDMMAAALVGAGEAVANRLSAGDTDVDEAAEMMIDL
MAB_2458c|M.abscessus_ATCC_199 VAALLREAGLARPDSIARQVQLLYDGALTGSKIDKSVVPITLARRLTRQL
MMAR_2062|M.marinum_M VRERAVAAGLHDVEDFAWSWHILMKGAIILAAVGDPDSARRAQRMAQVLI
Mflv_5008|M.gilvum_PYR-GCK LLERARELGTVAADTDLDVAIDMMVGAITYRVLRPNPPDVDEMRRYLREV
: : *
Mb3198c|M.bovis_AF2122/97 IDQATARPV------------
Rv3173c|M.tuberculosis_H37Rv IDQATARPV------------
MSMEG_6503|M.smegmatis_MC2_155 LTAAGL---------------
MAV_1243|M.avium_104 VERAIPPTAR-----------
Mvan_4792|M.vanbaalenii_PYR-1 LTAAGL---------------
TH_3775|M.thermoresistible__bu LISAS----------------
MLBr_02568|M.leprae_Br4923 FWHGLKGAPADRDFGPSIVAG
MUL_1163|M.ulcerans_Agy99 LWRGLKGAPSDREIGSNFAAG
MAB_2458c|M.abscessus_ATCC_199 IG-------------------
MMAR_2062|M.marinum_M EQHRAAGAAAC----------
Mflv_5008|M.gilvum_PYR-GCK YRQAGLLPPG-----------