For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERLLARNGWRSTSLAQIAREAGVTPAGLLHHFESK EQLLNAVLDARDADDDAHADRSGDLIAELTRVPKRFERSPELVGTFMVLLAENLAPDAPLHDRLHQRYRA AADIIKDLITRGQQKGLYRKDFDAATKATEILAFINGMEIQWLLDPSIPLTEVYQGYAESLARDLAAQPS PT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | - | 100% (213) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2015 | - | 8e-10 | 23.50% (183) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5283 | - | 3e-08 | 26.15% (195) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 3e-08 | 28.82% (170) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2447 | - | 1e-101 | 86.96% (207) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 3e-08 | 28.82% (170) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 2e-06 | 42.86% (56) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3193c | - | 5e-15 | 30.37% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4739 | - | 2e-77 | 72.22% (198) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0910 | - | 3e-75 | 71.35% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4831 | - | 1e-79 | 70.87% (206) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0256 | - | 2e-85 | 77.27% (198) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 9e-11 | 28.07% (171) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0335|M.bovis_AF2122/97 ----------------------MQQQRTNRDKLLDGALACLRERGYGNTS
Rv0328|M.tuberculosis_H37Rv ----------------------MQQQRTNRDKLLDGALACLRERGYGNTS
Mvan_4204|M.vanbaalenii_PYR-1 -MSAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERLLARNGWRSTS
Mflv_2447|M.gilvum_PYR-GCK -MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTS
MSMEG_4831|M.smegmatis_MC2_155 -----MTPPQGQAEAARPYETLLAKGEDRRQRILSVAERLLARNGWRNTS
TH_0256|M.thermoresistible__bu ------------VTQTRPYETLLAKGEDRRQRILAVAERLLARNGWRNTS
MMAR_4739|M.marinum_M ------------MPEVRPYDTLLAKGEDRKQRILGVAQRLLSRNGWRNTT
MAV_0910|M.avium_104 ------------MPVARRYDTLLAKGEDRKQRILDVAQRLLTRNGWRNTT
MAB_3193c|M.abscessus_ATCC_199 ------------MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGAS
MUL_4876|M.ulcerans_Agy99 ------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQAS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
.: :: * : . :
Mb0335|M.bovis_AF2122/97 SRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRA
Rv0328|M.tuberculosis_H37Rv SRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRA
Mvan_4204|M.vanbaalenii_PYR-1 LAQIAREAGVTPAGLLHHFESKEQLLNAVLD----------ARDADDDAH
Mflv_2447|M.gilvum_PYR-GCK LAQIAREAGVTPAGLLHHFESKEQLLNAVLD----------ARDADDDAH
MSMEG_4831|M.smegmatis_MC2_155 LAQIAKEAGVTTAGLLHHFESKEHLLNAVLD----------ARDLDDDAH
TH_0256|M.thermoresistible__bu LAQIAKEAGVSPAGLLHHFESKEALLNAVLD----------ARDADDDAH
MMAR_4739|M.marinum_M LAQIAGEAGVTPAGLLHHFESKEQLLHAVLD----------ARDLDDDAH
MAV_0910|M.avium_104 LAQIAGEAGVTPAGLLHHFESKEQLLHAVLD----------ARDLDDDTH
MAB_3193c|M.abscessus_ATCC_199 MRVIAKEANISLAGLMHYFPTRDVILTEIQRG---------ADATFEERY
MUL_4876|M.ulcerans_Agy99 IREIAKAADMTSGSLYHYFPNKSELLNATAT------EIEEIVLPRLHAA
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLN-----MKSRSAVEALA
:* *.:. : .:* .:. :*
Mb0335|M.bovis_AF2122/97 AGPAGQILA---VLEATVDSFEQIRPAVYACVESYAPALRSEA-LRERLA
Rv0328|M.tuberculosis_H37Rv AGPAGQILA---VLEATVDSFEQIRPAVYACVESYAPALRSEA-LRERLA
Mvan_4204|M.vanbaalenii_PYR-1 ADRSGDLIA---ELTRVPKRFERSPELVGTFMVLLAENLAPDAPLHDRLH
Mflv_2447|M.gilvum_PYR-GCK ADRGGDLVT---ELARVPERFERSPELVGTFMVLLAENIAPDAPLHDRLH
MSMEG_4831|M.smegmatis_MC2_155 ADRSGDLAD---EIKRVAERFVRAPELVGTFTVLLVENIQPDAPLHDRLL
TH_0256|M.thermoresistible__bu ADRSGDLIA---EIARVAERFDRAPHLVGTFTVLLVENIQPEAPLHDRML
MMAR_4739|M.marinum_M ADRLGDLIG---EIAQVADRFTRAPELVGTFTVLLAENIDPDAPLHDRLV
MAV_0910|M.avium_104 ADRTGDLFD---QIAAVADRFYRAPELVGTFTVLLVENILPEAPLHDRML
MAB_3193c|M.abscessus_ATCC_199 RNSEIELDPGEVLAQAMLDKANKPGSGTVYLSLAAAAAVDPEHPAGAYLR
MUL_4876|M.ulcerans_Agy99 AASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTY
MLBr_01070|M.leprae_Br4923 EQLPADPAA---VWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWS
: . .
Mb0335|M.bovis_AF2122/97 AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWI--
Rv0328|M.tuberculosis_H37Rv AGYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWI--
Mvan_4204|M.vanbaalenii_PYR-1 QRYRAAADIIKDLITRGQQKGLYRKDFDAATKATEILAFINGMEIQWL--
Mflv_2447|M.gilvum_PYR-GCK KRYRDAVDIIEDIITRGQRKGLYRTDFDAASKATEILAFINGMETLWL--
MSMEG_4831|M.smegmatis_MC2_155 KRQQDARDIVADIIRRGQRSGRYRPDFDPVIKAVEILAFVNGMETSWL--
TH_0256|M.thermoresistible__bu ARQRAAIDIVADLIRRGQESGRYRSDFDAATKAVEIIAFVNGMETSWL--
MMAR_4739|M.marinum_M SRQRDACEIVAEAIRRGQEAGRYRADLDPTVKAVEILAFIHGMEMTWL--
MAV_0910|M.avium_104 ARHRAATDIVADLIRRGQADGRYRADIDPAVKAVEILAFVHGMETTWL--
MAB_3193c|M.abscessus_ATCC_199 DRYERMRARIAAYVRGRQVDGTVPAHVDADFAATALIAAADGIQIQWM--
MUL_4876|M.ulcerans_Agy99 PGSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAAN-
MLBr_01070|M.leprae_Br4923 TVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSD
. : :
Mb0335|M.bovis_AF2122/97 ADPSATPRSTEVIRALASIGAVVTSQLR-----
Rv0328|M.tuberculosis_H37Rv ADPSATPRSTEVIRALASIGAVVTSQLR-----
Mvan_4204|M.vanbaalenii_PYR-1 LDPSIP--LTEVYQGYAESLARDLAAQPSPT--
Mflv_2447|M.gilvum_PYR-GCK LDPSIP--LTEVFKGYAESLGRDLAL-------
MSMEG_4831|M.smegmatis_MC2_155 LDPSLP--LQDVFKGYAEMLAREIELT------
TH_0256|M.thermoresistible__bu LDPSIP--VAEVFKGYAEMLERDFAPPNPT---
MMAR_4739|M.marinum_M LDPSIP--LTEVFKEYAEALARDFSLP---STT
MAV_0910|M.avium_104 LDPSIP--LPEVFKQYAETLARDFAPPKRAETT
MAB_3193c|M.abscessus_ATCC_199 SDPSID--MGEHMRRVWELLLR-----------
MUL_4876|M.ulcerans_Agy99 LGPQSYDVTLDSAKQLLRGSLFAGAKPTATRRT
MLBr_01070|M.leprae_Br4923 EKPLIP--DKKVIDTLVHIWLASIYGS------
* .