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PEVRPYDTLLAKGEDRKQRILGVAQRLLSRNGWRNTTLAQIAGEAGVTPAGLLHHFESKEQLLHAVLDAR DLDDDAHADRLGDLIGEIAQVADRFTRAPELVGTFTVLLAENIDPDAPLHDRLVSRQRDACEIVAEAIRR GQEAGRYRADLDPTVKAVEILAFIHGMEMTWLLDPSIPLTEVFKEYAEALARDFSLPSTT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4739 | - | - | 100% (201) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3142 | - | 1e-08 | 27.16% (162) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1394 | - | 2e-07 | 28.41% (176) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2184c | - | 2e-08 | 25.43% (173) | hypothetical protein Mb2184c |
| M. gilvum PYR-GCK | Mflv_2447 | - | 8e-79 | 74.61% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 8e-08 | 28.32% (173) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 3e-05 | 28.57% (84) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3193c | - | 7e-13 | 26.06% (188) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0910 | - | 2e-90 | 81.82% (198) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4831 | - | 1e-83 | 77.20% (193) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0256 | - | 8e-85 | 74.63% (201) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 2e-07 | 25.00% (168) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 2e-77 | 72.22% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4739|M.marinum_M ------------MPEVRPYDTLLAKGEDRKQRILGVAQRLLSRNGWRNTT
MAV_0910|M.avium_104 ------------MPVARRYDTLLAKGEDRKQRILDVAQRLLTRNGWRNTT
MSMEG_4831|M.smegmatis_MC2_155 -----MTPPQGQAEAARPYETLLAKGEDRRQRILSVAERLLARNGWRNTS
TH_0256|M.thermoresistible__bu ------------VTQTRPYETLLAKGEDRRQRILAVAERLLARNGWRNTS
Mflv_2447|M.gilvum_PYR-GCK -MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTS
Mvan_4204|M.vanbaalenii_PYR-1 -MSAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERLLARNGWRSTS
MAB_3193c|M.abscessus_ATCC_199 ------------MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGAS
Mb2184c|M.bovis_AF2122/97 -------------------MPSADVGRQTRAQILRAAMDIASVKGLSGLS
MUL_4876|M.ulcerans_Agy99 ------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQAS
Rv3167c|M.tuberculosis_H37Rv -------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
. *: .: :
MMAR_4739|M.marinum_M LAQIAGEAGVTPAGLLHHFESKEQLLHAVLDARDLDDDAHADRLGDLI--
MAV_0910|M.avium_104 LAQIAGEAGVTPAGLLHHFESKEQLLHAVLDARDLDDDTHADRTGDLF--
MSMEG_4831|M.smegmatis_MC2_155 LAQIAKEAGVTTAGLLHHFESKEHLLNAVLDARDLDDDAHADRSGDLA--
TH_0256|M.thermoresistible__bu LAQIAKEAGVSPAGLLHHFESKEALLNAVLDARDADDDAHADRSGDLI--
Mflv_2447|M.gilvum_PYR-GCK LAQIAREAGVTPAGLLHHFESKEQLLNAVLDARDADDDAHADRGGDLV--
Mvan_4204|M.vanbaalenii_PYR-1 LAQIAREAGVTPAGLLHHFESKEQLLNAVLDARDADDDAHADRSGDLI--
MAB_3193c|M.abscessus_ATCC_199 MRVIAKEANISLAGLMHYFPTRDVILTEIQRGADATFEERYRNSEIEL--
Mb2184c|M.bovis_AF2122/97 IGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFEAEVVAPAMAA--
MUL_4876|M.ulcerans_Agy99 IREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAASS--
Rv3167c|M.tuberculosis_H37Rv LAAVAERAGTTKSALYRRWSSKAELVHEAAFP--AAPTALQAAAGDIA--
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :* . : : : : :
MMAR_4739|M.marinum_M GEIAQVADRFTRAPELVGTFTVLL--------AENIDP-DAPLHDRLVSR
MAV_0910|M.avium_104 DQIAAVADRFYRAPELVGTFTVLL--------VENILP-EAPLHDRMLAR
MSMEG_4831|M.smegmatis_MC2_155 DEIKRVAERFVRAPELVGTFTVLL--------VENIQP-DAPLHDRLLKR
TH_0256|M.thermoresistible__bu AEIARVAERFDRAPHLVGTFTVLL--------VENIQP-EAPLHDRMLAR
Mflv_2447|M.gilvum_PYR-GCK TELARVPERFERSPELVGTFMVLL--------AENIAP-DAPLHDRLHKR
Mvan_4204|M.vanbaalenii_PYR-1 AELTRVPKRFERSPELVGTFMVLL--------AENLAP-DAPLHDRLHQR
MAB_3193c|M.abscessus_ATCC_199 DPGEVLAQAMLDKANKPGSGTVYLS----LAAAAAVDP-EHPAGAYLRDR
Mb2184c|M.bovis_AF2122/97 PPGVDRVRALMHAWVGYLERDVFPGGCFFAAAAADVDSQPGPVRDRIAAT
MUL_4876|M.ulcerans_Agy99 DDIVDRLDAVLDESKRLMRDYPYLAG--FLRAVRAENADQTGGGRRTYPG
Rv3167c|M.tuberculosis_H37Rv ADIRMMIAATRDVFTTPVVRAALPG-------LVADMTADAELNARVLAR
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAG------AAAKATSPEVRRLWSTV
.
MMAR_4739|M.marinum_M QRDACEIVAEAIRRGQEAGRYRADLDPTVKAVEILAFIHGMEMTWLLD--
MAV_0910|M.avium_104 HRAATDIVADLIRRGQADGRYRADIDPAVKAVEILAFVHGMETTWLLD--
MSMEG_4831|M.smegmatis_MC2_155 QQDARDIVADIIRRGQRSGRYRPDFDPVIKAVEILAFVNGMETSWLLD--
TH_0256|M.thermoresistible__bu QRAAIDIVADLIRRGQESGRYRSDFDAATKAVEIIAFVNGMETSWLLD--
Mflv_2447|M.gilvum_PYR-GCK YRDAVDIIEDIITRGQRKGLYRTDFDAASKATEILAFINGMETLWLLD--
Mvan_4204|M.vanbaalenii_PYR-1 YRAAADIIKDLITRGQQKGLYRKDFDAATKATEILAFINGMEIQWLLD--
MAB_3193c|M.abscessus_ATCC_199 YERMRARIAAYVRGRQVDGTVPAHVDADFAATALIAAADGIQIQWMSD--
Mb2184c|M.bovis_AF2122/97 GRAGIAAITADVETAQRRGEIRADIEARQLAFELHAYAMEANWALLLL--
MUL_4876|M.ulcerans_Agy99 SKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAANL--
Rv3167c|M.tuberculosis_H37Rv FADLFAAVRMRLREAVDRGEAHPDVDPD-RLIELIGGATMLRMLLYPD--
MLBr_01070|M.leprae_Br4923 MQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEK
: * . . :
MMAR_4739|M.marinum_M PSIPLTEVFKEYAEALARDFSLP---STT---
MAV_0910|M.avium_104 PSIPLPEVFKQYAETLARDFAPPKRAETT---
MSMEG_4831|M.smegmatis_MC2_155 PSLPLQDVFKGYAEMLAREIELT---------
TH_0256|M.thermoresistible__bu PSIPVAEVFKGYAEMLERDFAPPNPT------
Mflv_2447|M.gilvum_PYR-GCK PSIPLTEVFKGYAESLGRDLAL----------
Mvan_4204|M.vanbaalenii_PYR-1 PSIPLTEVYQGYAESLARDLAAQPSPT-----
MAB_3193c|M.abscessus_ATCC_199 PSIDMGEHMRRVWELLLR--------------
Mb2184c|M.bovis_AF2122/97 DDDGAGERARTAIDAALARVGTTQEGVES---
MUL_4876|M.ulcerans_Agy99 GPQSYDVTLDSAKQLLRGSLFAGAKPTATRRT
Rv3167c|M.tuberculosis_H37Rv DMLDDAWVDQTTAIVVRGVHRAAPGGSVV---
MLBr_01070|M.leprae_Br4923 PLIPDKKVIDTLVHIWLASIYGS---------