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TPPQGQAEAARPYETLLAKGEDRRQRILSVAERLLARNGWRNTSLAQIAKEAGVTTAGLLHHFESKEHLL NAVLDARDLDDDAHADRSGDLADEIKRVAERFVRAPELVGTFTVLLVENIQPDAPLHDRLLKRQQDARDI VADIIRRGQRSGRYRPDFDPVIKAVEILAFVNGMETSWLLDPSLPLQDVFKGYAEMLAREIELT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4831 | - | - | 100% (205) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 7e-09 | 26.57% (143) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 1e-08 | 32.93% (164) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 2e-08 | 32.35% (136) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2447 | - | 1e-82 | 77.72% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 2e-08 | 32.35% (136) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 9e-07 | 38.81% (67) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3193c | - | 3e-15 | 28.11% (185) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4739 | - | 1e-83 | 77.20% (193) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0910 | - | 9e-83 | 78.01% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0256 | - | 2e-88 | 84.74% (190) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 2e-10 | 28.57% (168) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 1e-79 | 70.87% (206) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3192c|M.bovis_AF2122/97 -------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLS
Rv3167c|M.tuberculosis_H37Rv -------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLS
MSMEG_4831|M.smegmatis_MC2_155 -----MTPPQGQAEAARPYETLLAKGEDRRQRILSVAERLLARNGWRNTS
TH_0256|M.thermoresistible__bu ------------VTQTRPYETLLAKGEDRRQRILAVAERLLARNGWRNTS
MMAR_4739|M.marinum_M ------------MPEVRPYDTLLAKGEDRKQRILGVAQRLLSRNGWRNTT
MAV_0910|M.avium_104 ------------MPVARRYDTLLAKGEDRKQRILDVAQRLLTRNGWRNTT
Mflv_2447|M.gilvum_PYR-GCK -MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTS
Mvan_4204|M.vanbaalenii_PYR-1 -MSAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERLLARNGWRSTS
MAB_3193c|M.abscessus_ATCC_199 ------------MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGAS
MUL_4876|M.ulcerans_Agy99 ------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQAS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
. . *: .: : . :
Mb3192c|M.bovis_AF2122/97 LAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAA--D
Rv3167c|M.tuberculosis_H37Rv LAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAA--D
MSMEG_4831|M.smegmatis_MC2_155 LAQIAKEAGVTTAGLLHHFESKEHLLN--AVLDARDLDDDAHADRSG--D
TH_0256|M.thermoresistible__bu LAQIAKEAGVSPAGLLHHFESKEALLN--AVLDARDADDDAHADRSG--D
MMAR_4739|M.marinum_M LAQIAGEAGVTPAGLLHHFESKEQLLH--AVLDARDLDDDAHADRLG--D
MAV_0910|M.avium_104 LAQIAGEAGVTPAGLLHHFESKEQLLH--AVLDARDLDDDTHADRTG--D
Mflv_2447|M.gilvum_PYR-GCK LAQIAREAGVTPAGLLHHFESKEQLLN--AVLDARDADDDAHADRGG--D
Mvan_4204|M.vanbaalenii_PYR-1 LAQIAREAGVTPAGLLHHFESKEQLLN--AVLDARDADDDAHADRSG--D
MAB_3193c|M.abscessus_ATCC_199 MRVIAKEANISLAGLMHYFPTRDVILT-EIQRGADATFEERYRNSEI--E
MUL_4876|M.ulcerans_Agy99 IREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAASSDD
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLL--SLLDDLNMKSRSAVEALAEQL
: :* *. : : : .: ::
Mb3192c|M.bovis_AF2122/97 IRM---MIAATRDVFTTP--VVRAALPGLVADMTADAELNARVLARFADL
Rv3167c|M.tuberculosis_H37Rv IRM---MIAATRDVFTTP--VVRAALPGLVADMTADAELNARVLARFADL
MSMEG_4831|M.smegmatis_MC2_155 LAD---EIKRVAERFVRAPELVGTFTVLLVENIQPDAPLHDRLLKRQQDA
TH_0256|M.thermoresistible__bu LIA---EIARVAERFDRAPHLVGTFTVLLVENIQPEAPLHDRMLARQRAA
MMAR_4739|M.marinum_M LIG---EIAQVADRFTRAPELVGTFTVLLAENIDPDAPLHDRLVSRQRDA
MAV_0910|M.avium_104 LFD---QIAAVADRFYRAPELVGTFTVLLVENILPEAPLHDRMLARHRAA
Mflv_2447|M.gilvum_PYR-GCK LVT---ELARVPERFERSPELVGTFMVLLAENIAPDAPLHDRLHKRYRDA
Mvan_4204|M.vanbaalenii_PYR-1 LIA---ELTRVPKRFERSPELVGTFMVLLAENLAPDAPLHDRLHQRYRAA
MAB_3193c|M.abscessus_ATCC_199 LDPGEVLAQAMLDKANKPGSGTVYLSLAAAAAVDPEHPAGAYLRDRYERM
MUL_4876|M.ulcerans_Agy99 IVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPGSKAL
MLBr_01070|M.leprae_Br4923 PADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQW
.
Mb3192c|M.bovis_AF2122/97 FAAVRMRLREAVDRGEAHPDVDPD-RLIELIGGATMLRMLLYPD--DMLD
Rv3167c|M.tuberculosis_H37Rv FAAVRMRLREAVDRGEAHPDVDPD-RLIELIGGATMLRMLLYPD--DMLD
MSMEG_4831|M.smegmatis_MC2_155 RDIVADIIRRGQRSGRYRPDFDPVIKAVEILAFVNGMETSWLLD--PSLP
TH_0256|M.thermoresistible__bu IDIVADLIRRGQESGRYRSDFDAATKAVEIIAFVNGMETSWLLD--PSIP
MMAR_4739|M.marinum_M CEIVAEAIRRGQEAGRYRADLDPTVKAVEILAFIHGMEMTWLLD--PSIP
MAV_0910|M.avium_104 TDIVADLIRRGQADGRYRADIDPAVKAVEILAFVHGMETTWLLD--PSIP
Mflv_2447|M.gilvum_PYR-GCK VDIIEDIITRGQRKGLYRTDFDAASKATEILAFINGMETLWLLD--PSIP
Mvan_4204|M.vanbaalenii_PYR-1 ADIIKDLITRGQQKGLYRKDFDAATKATEILAFINGMEIQWLLD--PSIP
MAB_3193c|M.abscessus_ATCC_199 RARIAAYVRGRQVDGTVPAHVDADFAATALIAAADGIQIQWMSD--PSID
MUL_4876|M.ulcerans_Agy99 RDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAANL--GPQS
MLBr_01070|M.leprae_Br4923 IDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIP
: * . . : :
Mb3192c|M.bovis_AF2122/97 DAWVDQTTAIVVRGVHRAAPGGSVV---
Rv3167c|M.tuberculosis_H37Rv DAWVDQTTAIVVRGVHRAAPGGSVV---
MSMEG_4831|M.smegmatis_MC2_155 LQDVFKGYAEMLAREIELT---------
TH_0256|M.thermoresistible__bu VAEVFKGYAEMLERDFAPPNPT------
MMAR_4739|M.marinum_M LTEVFKEYAEALARDFSLP---STT---
MAV_0910|M.avium_104 LPEVFKQYAETLARDFAPPKRAETT---
Mflv_2447|M.gilvum_PYR-GCK LTEVFKGYAESLGRDLAL----------
Mvan_4204|M.vanbaalenii_PYR-1 LTEVYQGYAESLARDLAAQPSPT-----
MAB_3193c|M.abscessus_ATCC_199 MGEHMRRVWELLLR--------------
MUL_4876|M.ulcerans_Agy99 YDVTLDSAKQLLRGSLFAGAKPTATRRT
MLBr_01070|M.leprae_Br4923 DKKVIDTLVHIWLASIYGS---------