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PSPTRGLTQPQRLELSARRLLEAAVALIGEKGWDATTAAEIGQRAGYSRAMVHARYGSKDALLETLFASE YEKKLSPSPDPGSDGMTQALAHLDRIALLYAEDPDLCRAVFVLTFEAAKTTSQAHPYIRMWLERAAHAVE AGLRKGIADGSVRPEVDIARAVNDFGAAVLGTAYQWIMQAYPYDIAEELAYVRARLVCDYCA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2015 | - | - | 100% (203) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 7e-10 | 23.50% (183) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 8e-07 | 31.63% (98) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 4e-05 | 22.56% (164) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2447 | - | 5e-07 | 23.60% (161) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 3e-05 | 21.95% (164) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1576 | - | 1e-06 | 38.03% (71) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0923 | - | 9e-08 | 26.45% (155) | transcriptional regulator |
| M. avium 104 | MAV_1977 | - | 4e-07 | 34.18% (79) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0148 | - | 4e-07 | 33.33% (78) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0256 | - | 2e-08 | 25.47% (161) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0675 | - | 8e-08 | 26.45% (155) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0310|M.bovis_AF2122/97 -------------MGVPAKKKQQQGERSRESILDATERLMATKGYAATSI
Rv0302|M.tuberculosis_H37Rv -------------MGVPAKKKQQQGERSRESILDATERLMATKGYAATSI
Mflv_2447|M.gilvum_PYR-GCK MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTSL
TH_0256|M.thermoresistible__bu -----------VTQTRPYETLLAKGEDRRQRILAVAERLLARNGWRNTSL
MMAR_0923|M.marinum_M -----------------MPTAAERGAQTRAALMAAAVAVIAERGWGAATT
MUL_0675|M.ulcerans_Agy99 -----------------MPTAAERGAQTRAALMAAAVAVIAERGWGAATT
MSMEG_0148|M.smegmatis_MC2_155 ------------MVPRKRLTRAEARAQTRRRLLDAAAETFARKGYDAASV
Mvan_2015|M.vanbaalenii_PYR-1 -----------MPSPTRGLTQPQRLELSARRLLEAAVALIGEKGWDATTA
MAV_1977|M.avium_104 -------------MTRRRAGEPRKGDLREAAILDAAEELLGAIGYDAMTI
MAB_1576|M.abscessus_ATCC_1997 MTRPGAPLGKLMARAVRGLGSHPEPDDIETRLLDAAIEVLSERGTQTATI
:: .: :. * :
Mb0310|M.bovis_AF2122/97 SDIRDACGLAPSSIYWHFGSK-EGVLAAMMERGAQRFFAAIPTWDEAHGP
Rv0302|M.tuberculosis_H37Rv SDIRDACGLAPSSIYWHFGSK-EGVLAAMMERGAQRFFAAIPTWDEAHGP
Mflv_2447|M.gilvum_PYR-GCK AQIAREAGVTPAGLLHHFESK-EQLLNAVLD--------ARDADDDAHAD
TH_0256|M.thermoresistible__bu AQIAKEAGVSPAGLLHHFESK-EALLNAVLD--------ARDADDDAHAD
MMAR_0923|M.marinum_M RMVAERAGLPPGLVHYHFASLNDLLIDAALQAAR---EEAAQVLDGLAGD
MUL_0675|M.ulcerans_Agy99 RMVAERAGLPPGLVHYHFASLNDLLIDAALQAAR---EEAAQVLDGLAGD
MSMEG_0148|M.smegmatis_MC2_155 EEIAEAAGYSVGAVYSNFSSKEQLFSELRSERAALRLDEVADALRSAQGD
Mvan_2015|M.vanbaalenii_PYR-1 AEIGQRAGYSRAMVHARYGSK-DALLETLFASEY---EKKLSPSPDPGSD
MAV_1977|M.avium_104 ADIAARAGITRGALYFYFGSK-QEVITALFAR-------TVAVLHEKSRA
MAB_1576|M.abscessus_ATCC_1997 DEVARRAKVGRATVFRRFSSK-DQLFERALAQEMRKFLDELQARAGEFDD
: . . : : * : .
Mb0310|M.bovis_AF2122/97 VEQRSERQLTELVSLQSQHPDFLRLFYLLSME--RSQDPVVAAVVRRVRN
Rv0302|M.tuberculosis_H37Rv VEQRSERQLTELVSLQSQHPDFLRLFYLLSME--RSQDPAVAAVVRRVRN
Mflv_2447|M.gilvum_PYR-GCK RGGDLVTELARVPERFERSPELVGTFMVLLAENIAPDAPLHDRLHKRYR-
TH_0256|M.thermoresistible__bu RSGDLIAEIARVAERFDRAPHLVGTFTVLLVENIQPEAPLHDRMLARQR-
MMAR_0923|M.marinum_M SPSQGIDRLIDAVSSYDVD-DRNQNPAILVFG----EMLLAATRYERLRM
MUL_0675|M.ulcerans_Agy99 SSSQGIDRLIDAVSSYDVD-DRNQNPAILVFG----EMLLAATRYERLRM
MSMEG_0148|M.smegmatis_MC2_155 PGGPFAKLSRQLVEVADKNIEVAALHTEFWLH--AIRNPGAMDVLAESVG
Mvan_2015|M.vanbaalenii_PYR-1 GMTQALAHLDRIALLYAEDPDLCRAVFVLTFEA-AKTTSQAHPYIRMWLE
MAV_1977|M.avium_104 ATEDAASGAKAIDTAMRRTEDLWREHGVVMRT--AIDLAATVPQLDALWK
MAB_1576|M.abscessus_ATCC_1997 IGERVAEGFAVCIEIVNHPLLRGDSLVARMTAVEAITQGDPAPIELARNY
Mb0310|M.bovis_AF2122/97 TAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPD
Rv0302|M.tuberculosis_H37Rv TAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPD
Mflv_2447|M.gilvum_PYR-GCK DAVDIIEDIITRGQRKGL--YRTDFDAASKATEILAFINGMETLWLLDP-
TH_0256|M.thermoresistible__bu AAIDIVADLIRRGQESGR--YRSDFDAATKAVEIIAFVNGMETSWLLDP-
MMAR_0923|M.marinum_M GLAEILGDYRS-ALRQWLADQGGAIDPEATAALMFAAIDGLVLHRVIDPR
MUL_0675|M.ulcerans_Agy99 GLAEILGDYRS-TLRQWLADQGGAIDPEATAALMFAAIDGLVLHRVIDPR
MSMEG_0148|M.smegmatis_MC2_155 QTLQSLTGIAADLLAEHN-VDQSVVRPETFAVSLLALHQGLIRQRRTNP-
Mvan_2015|M.vanbaalenii_PYR-1 RAAHAVEAGLRKGIADGS--VRPEVDIARAVNDFGAAVLGTAYQWIMQAY
MAV_1977|M.avium_104 QTADIFVVAITAILEHMGVPAGKGPDKSAAIAEALCWMIERNFYQASRVS
MAB_1576|M.abscessus_ATCC_1997 LAAQIDQMREEGRIPPGDSRRQVDVLIHLVLGYLAAPATTIDLGNTEEVR
.
Mb0310|M.bovis_AF2122/97 --TTDVERMYRRLRQALEALIPVLLEET
Rv0302|M.tuberculosis_H37Rv --TTDVERMYRRLRQALEALIPVLLEET
Mflv_2447|M.gilvum_PYR-GCK --SIPLTEVFKGYAESLGRDLAL-----
TH_0256|M.thermoresistible__bu --SIPVAEVFKGYAEMLERDFAPPNPT-
MMAR_0923|M.marinum_M LRTLAIRPALRRLAGLPTAQTDERTPP-
MUL_0675|M.ulcerans_Agy99 LRTLAIRPTLRRLAGLPTAQTDERTPS-
MSMEG_0148|M.smegmatis_MC2_155 --SWVPEELFGQLLSWLLAGMPKLPAH-
Mvan_2015|M.vanbaalenii_PYR-1 --PYDIAEELAYVRARLVCDYCA-----
MAV_1977|M.avium_104 --PARLTRARQTCTEIWLRVAS------
MAB_1576|M.abscessus_ATCC_1997 ---ALARETFAPILLTPNVPLKAP----