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SAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGASMRVIAKEANISLAGLMHYFPTRDVILTEIQRGA DATFEERYRNSEIELDPGEVLAQAMLDKANKPGSGTVYLSLAAAAAVDPEHPAGAYLRDRYERMRARIAA YVRGRQVDGTVPAHVDADFAATALIAAADGIQIQWMSDPSIDMGEHMRRVWELLLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3193c | - | - | 100% (197) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2543c | - | 2e-05 | 24.19% (186) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1552 | - | 4e-05 | 33.33% (54) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 2e-09 | 28.18% (181) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2447 | - | 2e-12 | 26.84% (190) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 2e-09 | 28.18% (181) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4739 | - | 9e-13 | 26.06% (188) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0910 | - | 7e-14 | 27.03% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4831 | - | 3e-15 | 28.11% (185) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0256 | - | 2e-15 | 32.63% (190) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 4e-07 | 26.79% (168) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 6e-15 | 30.37% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0335|M.bovis_AF2122/97 ---------------------MQQQRTNRDKLLDGALACLRERGYGNTSS
Rv0328|M.tuberculosis_H37Rv ---------------------MQQQRTNRDKLLDGALACLRERGYGNTSS
MSMEG_4831|M.smegmatis_MC2_155 ----MTPPQGQAEAARPYETLLAKGEDRRQRILSVAERLLARNGWRNTSL
TH_0256|M.thermoresistible__bu -----------VTQTRPYETLLAKGEDRRQRILAVAERLLARNGWRNTSL
MMAR_4739|M.marinum_M -----------MPEVRPYDTLLAKGEDRKQRILGVAQRLLSRNGWRNTTL
MAV_0910|M.avium_104 -----------MPVARRYDTLLAKGEDRKQRILDVAQRLLTRNGWRNTTL
Mflv_2447|M.gilvum_PYR-GCK MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTSL
Mvan_4204|M.vanbaalenii_PYR-1 MSAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERLLARNGWRSTSL
MAB_3193c|M.abscessus_ATCC_199 -----------MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGASM
MUL_4876|M.ulcerans_Agy99 -----MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQASI
: . ::.:: * : . * ::
Mb0335|M.bovis_AF2122/97 RDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAA
Rv0328|M.tuberculosis_H37Rv RDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAA
MSMEG_4831|M.smegmatis_MC2_155 AQIAKEAGVTTAGLLHHFESKEHLLNAVLD----------ARDLDDDAHA
TH_0256|M.thermoresistible__bu AQIAKEAGVSPAGLLHHFESKEALLNAVLD----------ARDADDDAHA
MMAR_4739|M.marinum_M AQIAGEAGVTPAGLLHHFESKEQLLHAVLD----------ARDLDDDAHA
MAV_0910|M.avium_104 AQIAGEAGVTPAGLLHHFESKEQLLHAVLD----------ARDLDDDTHA
Mflv_2447|M.gilvum_PYR-GCK AQIAREAGVTPAGLLHHFESKEQLLNAVLD----------ARDADDDAHA
Mvan_4204|M.vanbaalenii_PYR-1 AQIAREAGVTPAGLLHHFESKEQLLNAVLD----------ARDADDDAHA
MAB_3193c|M.abscessus_ATCC_199 RVIAKEANISLAGLMHYFPTRDVILTEIQRG---------ADATFEERYR
MUL_4876|M.ulcerans_Agy99 REIAKAADMTSGSLYHYFPNKSELLNATAT------EIEEIVLPRLHAAA
** *.:. ..: ::* .:. :*
Mb0335|M.bovis_AF2122/97 GPAGQILA---VLEATVDSFEQIRPAVYACVESYAPALRSEA-LRERLAA
Rv0328|M.tuberculosis_H37Rv GPAGQILA---VLEATVDSFEQIRPAVYACVESYAPALRSEA-LRERLAA
MSMEG_4831|M.smegmatis_MC2_155 DRSGDLAD---EIKRVAERFVRAPELVGTFTVLLVENIQPDAPLHDRLLK
TH_0256|M.thermoresistible__bu DRSGDLIA---EIARVAERFDRAPHLVGTFTVLLVENIQPEAPLHDRMLA
MMAR_4739|M.marinum_M DRLGDLIG---EIAQVADRFTRAPELVGTFTVLLAENIDPDAPLHDRLVS
MAV_0910|M.avium_104 DRTGDLFD---QIAAVADRFYRAPELVGTFTVLLVENILPEAPLHDRMLA
Mflv_2447|M.gilvum_PYR-GCK DRGGDLVT---ELARVPERFERSPELVGTFMVLLAENIAPDAPLHDRLHK
Mvan_4204|M.vanbaalenii_PYR-1 DRSGDLIA---ELTRVPKRFERSPELVGTFMVLLAENLAPDAPLHDRLHQ
MAB_3193c|M.abscessus_ATCC_199 NSEIELDPGEVLAQAMLDKANKPGSGTVYLSLAAAAAVDPEHPAGAYLRD
MUL_4876|M.ulcerans_Agy99 ASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYP
:: . : :
Mb0335|M.bovis_AF2122/97 GYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWI-AD
Rv0328|M.tuberculosis_H37Rv GYADVRQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWI-AD
MSMEG_4831|M.smegmatis_MC2_155 RQQDARDIVADIIRRGQRSGRYRPDFDPVIKAVEILAFVNGMETSWL-LD
TH_0256|M.thermoresistible__bu RQRAAIDIVADLIRRGQESGRYRSDFDAATKAVEIIAFVNGMETSWL-LD
MMAR_4739|M.marinum_M RQRDACEIVAEAIRRGQEAGRYRADLDPTVKAVEILAFIHGMEMTWL-LD
MAV_0910|M.avium_104 RHRAATDIVADLIRRGQADGRYRADIDPAVKAVEILAFVHGMETTWL-LD
Mflv_2447|M.gilvum_PYR-GCK RYRDAVDIIEDIITRGQRKGLYRTDFDAASKATEILAFINGMETLWL-LD
Mvan_4204|M.vanbaalenii_PYR-1 RYRAAADIIKDLITRGQQKGLYRKDFDAATKATEILAFINGMEIQWL-LD
MAB_3193c|M.abscessus_ATCC_199 RYERMRARIAAYVRGRQVDGTVPAHVDADFAATALIAAADGIQIQWM-SD
MUL_4876|M.ulcerans_Agy99 GSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAANLG
. : * *: .
Mb0335|M.bovis_AF2122/97 PSATPRSTEVIRALASIGAVVTSQLR-----
Rv0328|M.tuberculosis_H37Rv PSATPRSTEVIRALASIGAVVTSQLR-----
MSMEG_4831|M.smegmatis_MC2_155 PSLP--LQDVFKGYAEMLAREIELT------
TH_0256|M.thermoresistible__bu PSIP--VAEVFKGYAEMLERDFAPPNPT---
MMAR_4739|M.marinum_M PSIP--LTEVFKEYAEALARDFSLP---STT
MAV_0910|M.avium_104 PSIP--LPEVFKQYAETLARDFAPPKRAETT
Mflv_2447|M.gilvum_PYR-GCK PSIP--LTEVFKGYAESLGRDLAL-------
Mvan_4204|M.vanbaalenii_PYR-1 PSIP--LTEVYQGYAESLARDLAAQPSPT--
MAB_3193c|M.abscessus_ATCC_199 PSID--MGEHMRRVWELLLR-----------
MUL_4876|M.ulcerans_Agy99 PQSYDVTLDSAKQLLRGSLFAGAKPTATRRT
*. : :