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VSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTSLAQIAREAGVTPAGLLHHFES KEQLLNAVLDARDADDDAHADRGGDLVTELARVPERFERSPELVGTFMVLLAENIAPDAPLHDRLHKRYR DAVDIIEDIITRGQRKGLYRTDFDAASKATEILAFINGMETLWLLDPSIPLTEVFKGYAESLGRDLAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2447 | - | - | 100% (208) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1947 | - | 4e-07 | 27.37% (190) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4467 | - | 7e-07 | 25.71% (175) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2184c | - | 1e-08 | 28.24% (170) | hypothetical protein Mb2184c |
| M. tuberculosis H37Rv | Rv1534 | - | 4e-08 | 27.74% (155) | transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 2e-06 | 42.86% (56) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3193c | - | 2e-12 | 26.84% (190) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4739 | - | 1e-78 | 74.61% (193) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0910 | - | 7e-76 | 72.40% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4831 | - | 2e-82 | 77.72% (193) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0256 | - | 3e-85 | 77.44% (195) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 9e-10 | 27.98% (168) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 1e-101 | 86.96% (207) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2447|M.gilvum_PYR-GCK -MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTS
Mvan_4204|M.vanbaalenii_PYR-1 -MSAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERLLARNGWRSTS
MSMEG_4831|M.smegmatis_MC2_155 -----MTPPQGQAEAARPYETLLAKGEDRRQRILSVAERLLARNGWRNTS
TH_0256|M.thermoresistible__bu ------------VTQTRPYETLLAKGEDRRQRILAVAERLLARNGWRNTS
MMAR_4739|M.marinum_M ------------MPEVRPYDTLLAKGEDRKQRILGVAQRLLSRNGWRNTT
MAV_0910|M.avium_104 ------------MPVARRYDTLLAKGEDRKQRILDVAQRLLTRNGWRNTT
MAB_3193c|M.abscessus_ATCC_199 ------------MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGAS
Mb2184c|M.bovis_AF2122/97 -------------------MPSADVGRQTRAQILRAAMDIASVKGLSGLS
MUL_4876|M.ulcerans_Agy99 ------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQAS
Rv1534|M.tuberculosis_H37Rv ---------MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATT
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
. *: .* :
Mflv_2447|M.gilvum_PYR-GCK LAQIAREAGVTPAGLLHHFESKEQLLNAVLDARDADDDAHADRGGDLV--
Mvan_4204|M.vanbaalenii_PYR-1 LAQIAREAGVTPAGLLHHFESKEQLLNAVLDARDADDDAHADRSGDLI--
MSMEG_4831|M.smegmatis_MC2_155 LAQIAKEAGVTTAGLLHHFESKEHLLNAVLDARDLDDDAHADRSGDLA--
TH_0256|M.thermoresistible__bu LAQIAKEAGVSPAGLLHHFESKEALLNAVLDARDADDDAHADRSGDLI--
MMAR_4739|M.marinum_M LAQIAGEAGVTPAGLLHHFESKEQLLHAVLDARDLDDDAHADRLGDLI--
MAV_0910|M.avium_104 LAQIAGEAGVTPAGLLHHFESKEQLLHAVLDARDLDDDTHADRTGDLF--
MAB_3193c|M.abscessus_ATCC_199 MRVIAKEANISLAGLMHYFPTRDVILTEIQRGADATFEERYRNSEIEL--
Mb2184c|M.bovis_AF2122/97 IGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFEAEVVAPAMAA--
MUL_4876|M.ulcerans_Agy99 IREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAASS--
Rv1534|M.tuberculosis_H37Rv VADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARV--
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :* .:: : :* :. :
Mflv_2447|M.gilvum_PYR-GCK TELARVPERFERSPELVGTFMVLL---------AENIAP-DAPLHDRLHK
Mvan_4204|M.vanbaalenii_PYR-1 AELTRVPKRFERSPELVGTFMVLL---------AENLAP-DAPLHDRLHQ
MSMEG_4831|M.smegmatis_MC2_155 DEIKRVAERFVRAPELVGTFTVLL---------VENIQP-DAPLHDRLLK
TH_0256|M.thermoresistible__bu AEIARVAERFDRAPHLVGTFTVLL---------VENIQP-EAPLHDRMLA
MMAR_4739|M.marinum_M GEIAQVADRFTRAPELVGTFTVLL---------AENIDP-DAPLHDRLVS
MAV_0910|M.avium_104 DQIAAVADRFYRAPELVGTFTVLL---------VENILP-EAPLHDRMLA
MAB_3193c|M.abscessus_ATCC_199 DPGEVLAQAMLDKANKPGSGTVYLS-----LAAAAAVDP-EHPAGAYLRD
Mb2184c|M.bovis_AF2122/97 PPGVDRVRALMHAWVGYLERDVFPGGCF-FAAAAADVDSQPGPVRDRIAA
MUL_4876|M.ulcerans_Agy99 DDIVDRLDAVLDESKRLMRDYPYLAG---FLRAVRAENADQTGGGRRTYP
Rv1534|M.tuberculosis_H37Rv GGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLGG
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAG-------AAAKATSPEVRRLWST
.
Mflv_2447|M.gilvum_PYR-GCK RYRDAVDIIEDIITRGQRKGLYRTDFDAASKATEILAFINGMETLWLL-D
Mvan_4204|M.vanbaalenii_PYR-1 RYRAAADIIKDLITRGQQKGLYRKDFDAATKATEILAFINGMEIQWLL-D
MSMEG_4831|M.smegmatis_MC2_155 RQQDARDIVADIIRRGQRSGRYRPDFDPVIKAVEILAFVNGMETSWLL-D
TH_0256|M.thermoresistible__bu RQRAAIDIVADLIRRGQESGRYRSDFDAATKAVEIIAFVNGMETSWLL-D
MMAR_4739|M.marinum_M RQRDACEIVAEAIRRGQEAGRYRADLDPTVKAVEILAFIHGMEMTWLL-D
MAV_0910|M.avium_104 RHRAATDIVADLIRRGQADGRYRADIDPAVKAVEILAFVHGMETTWLL-D
MAB_3193c|M.abscessus_ATCC_199 RYERMRARIAAYVRGRQVDGTVPAHVDADFAATALIAAADGIQIQWMS-D
Mb2184c|M.bovis_AF2122/97 TGRAGIAAITADVETAQRRGEIRADIEARQLAFELHAYAMEANWALLL-L
MUL_4876|M.ulcerans_Agy99 GSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAAN-L
Rv1534|M.tuberculosis_H37Rv IYERFIDDIEAVVVAAQRRG-EVVEAPSRMAAYTLAALVGQLAHRRLN-T
MLBr_01070|M.leprae_Br4923 VMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDE
. : : * . . :
Mflv_2447|M.gilvum_PYR-GCK PS-IPLTEVFKGYAESLGRDLAL---------------
Mvan_4204|M.vanbaalenii_PYR-1 PS-IPLTEVYQGYAESLARDLAAQPSPT----------
MSMEG_4831|M.smegmatis_MC2_155 PS-LPLQDVFKGYAEMLAREIELT--------------
TH_0256|M.thermoresistible__bu PS-IPVAEVFKGYAEMLERDFAPPNPT-----------
MMAR_4739|M.marinum_M PS-IPLTEVFKEYAEALARDFSLP---STT--------
MAV_0910|M.avium_104 PS-IPLPEVFKQYAETLARDFAPPKRAETT--------
MAB_3193c|M.abscessus_ATCC_199 PS-IDMGEHMRRVWELLLR-------------------
Mb2184c|M.bovis_AF2122/97 DD-DGAGERARTAIDAALARVGTTQEGVES--------
MUL_4876|M.ulcerans_Agy99 GP-QSYDVTLDSAKQLLRGSLFAGAKPTATRRT-----
Rv1534|M.tuberculosis_H37Rv DDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
MLBr_01070|M.leprae_Br4923 KPLIPDKKVIDTLVHIWLASIYGS--------------