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VQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQ EAFDHSRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHSVDLAGA ALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPRSTEVIRALASIGAVVTSQLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | - | 100% (200) | TetR/AcrR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb3587c | - | 9e-07 | 33.33% (96) | TetR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb3605 | - | 1e-05 | 35.44% (79) | transcriptional regulatory protein TetR-family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0941 | - | 1e-07 | 29.41% (153) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 1e-109 | 100.00% (200) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3193c | - | 3e-09 | 28.18% (181) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1597 | - | 3e-10 | 28.32% (173) | transcriptional regulatory protein |
| M. avium 104 | MAV_3767 | - | 3e-08 | 28.49% (172) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 1e-09 | 26.34% (186) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4317 | - | 4e-08 | 31.03% (116) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0675 | - | 5e-10 | 30.46% (197) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2569 | - | 8e-09 | 28.89% (180) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0335|M.bovis_AF2122/97 ---------------MQQQRTN----RDKLLDGALACLRERGYGNTSSRD
Rv0328|M.tuberculosis_H37Rv ---------------MQQQRTN----RDKLLDGALACLRERGYGNTSSRD
Mvan_2569|M.vanbaalenii_PYR-1 -------MSKIPPGPRDERGVL----SSRILVAARGAFADTGYAGTTIRA
MSMEG_1565|M.smegmatis_MC2_155 ----MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRCFAQFGYGPATNNQ
MUL_0675|M.ulcerans_Agy99 ------------MPTAAERGAQT---RAALMAAAVAVIAERGWGAATTRM
Mflv_0941|M.gilvum_PYR-GCK ----------------MDSGRR------RLIDAGLALLTEQADREPSTRE
MAV_3767|M.avium_104 ------------MARTQQQRREE--TVARLLDASIATIIEVGYARASAAV
MAB_3193c|M.abscessus_ATCC_199 ---------MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGASMRV
MMAR_1597|M.marinum_M MRAIAMVSNDHSGERVDGRRLRYRDRRGEILDAVMAHLLEHGISGMSFRT
TH_4317|M.thermoresistible__bu ---------------MSQQYDR-------MVDVVLSVLVSDGFEGVSVRK
:: : . :
Mb0335|M.bovis_AF2122/97 IARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRV-QEAFDHSRAAG
Rv0328|M.tuberculosis_H37Rv IARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRV-QEAFDHSRAAG
Mvan_2569|M.vanbaalenii_PYR-1 VARAADVDPALVYHYFGSKEALLDAATD-PPQRWLQNV-ARAWTTPVPQL
MSMEG_1565|M.smegmatis_MC2_155 IAEMAGVTAGSVYYHFGTKNKLFEAVCDDVYGKILTRV-MLAVSG--SHS
MUL_0675|M.ulcerans_Agy99 VAERAGLPPGLVHYHFASLNDLLIDAALQAAREEAAQV-LDGLAGDSSSQ
Mflv_0941|M.gilvum_PYR-GCK LYEAAGVAAPTLYHHFGTKEGLLEAVVTEAFSDYLERK-RAVPDSGDLVA
MAV_3767|M.avium_104 ITKRAGVSVGALFRHFDTMGDFMAATASEVLRRQLESFTKRVAEIPADQP
MAB_3193c|M.abscessus_ATCC_199 IAKEANISLAGLMHYFPTRDVILTEIQRGADATFEERYRNSEIELDPGEV
MMAR_1597|M.marinum_M LAAAAGVSHITLRHHFGTKDELLVEIFGVIGARVQIPD---HFGADDVES
TH_4317|M.thermoresistible__bu VAARANVSIGAVQHHFPTKDAMLQAAMDTAARRFRQRLAERMDPTMPAAE
: *.: : :* : ::
Mb0335|M.bovis_AF2122/97 PAGQILAVLEATVDSFEQIRPAVYACVESYAPALRS----EALRERLAAG
Rv0328|M.tuberculosis_H37Rv PAGQILAVLEATVDSFEQIRPAVYACVESYAPALRS----EALRERLAAG
Mvan_2569|M.vanbaalenii_PYR-1 GAALVRLMLDAWAD--EEIGPVLRAILQTAAHEAATR---EKLRLVVERS
MSMEG_1565|M.smegmatis_MC2_155 VVGLLRAVLTESMR-INHESPELAGFVATAPIDARRH---RELAESFATQ
MUL_0675|M.ulcerans_Agy99 GIDRLIDAVSSYDVDDRNQNPAILVFGEMLLAATRYERLRMGLAEILGDY
Mflv_0941|M.gilvum_PYR-GCK DFAAGWDMHIEFGVQNPVLYRLMFGQAEERRSSARDIAETELRRRLQLLA
MAV_3767|M.avium_104 VLEAVLGILRDLTS--GPVNAVIYELTVAARTDEKLR---ETLQHELAQY
MAB_3193c|M.abscessus_ATCC_199 LAQAMLDKANKPGSGTVYLSLAAAAAVDPEHPAGAYLR--DRYERMRARI
MMAR_1597|M.marinum_M LVRKMWQRWTEPQS-DRRSRLVFEAYAHAVRSPDEYR----AFLDRVVTG
TH_4317|M.thermoresistible__bu QLETVAVALACADPAERETAVTWLLRLARAAVNEQVAERHRSEWRALEAL
Mb0335|M.bovis_AF2122/97 YADVRQHSVDLAGAALAGTDI-----APPENLSTIVSVLMAVIDGLMIQW
Rv0328|M.tuberculosis_H37Rv YADVRQHSVDLAGAALAGTDI-----APPENLSTIVSVLMAVIDGLMIQW
Mvan_2569|M.vanbaalenii_PYR-1 LMGVSQLGVDERDRMLR---------------SGLISSQIMGLAMMRYVW
MSMEG_1565|M.smegmatis_MC2_155 GARMADALTDAVRSGQDAG----------DIAADLDPVRVARLISAVVDG
MUL_0675|M.ulcerans_Agy99 RSTLRQWLADQGGAIDP---------------EATAALMFAAIDGLVLHR
Mflv_0941|M.gilvum_PYR-GCK DEGLLRIDVDDAVSVTTGMAFGCVTQLIHSGGDATSAVAQAIRHALITEL
MAV_3767|M.avium_104 AAKIDEVSRALPGVEGFP--------------ADTFPVLVALMRNVFDGA
MAB_3193c|M.abscessus_ATCC_199 AAYVRGRQVDGTVPAHVD-------------ADFAATALIAAADGIQIQW
MMAR_1597|M.marinum_M WIEIIRYHALLAGCPSDE-------------ADTFATLLLAQLRGLQFDF
TH_4317|M.thermoresistible__bu LRDLIXXXHHARRACADR-------------GQLPHRAVLAGGQGTTAGG
:
Mb0335|M.bovis_AF2122/97 IADPSATPRSTEVIRALAS-IGAVVTSQLR--------------------
Rv0328|M.tuberculosis_H37Rv IADPSATPRSTEVIRALAS-IGAVVTSQLR--------------------
Mvan_2569|M.vanbaalenii_PYR-1 RIEPVASMDDDELVAAVAPNLQRYISDDLG--------------------
MSMEG_1565|M.smegmatis_MC2_155 FAHAAVSADPDEMDNMNELFQSLLLDTT----------------------
MUL_0675|M.ulcerans_Agy99 VIDPRLRTLAIRPTLRRLAGLPTAQTDERTPS------------------
Mflv_0941|M.gilvum_PYR-GCK TGSPVRHDDPAQAARQVLAGLGTMPALFTPAEEGLLRQWLRTVAEHLDTP
MAV_3767|M.avium_104 AVVEGVLPQP-EIAAQRIPVLTALLNAALPQ-------------------
MAB_3193c|M.abscessus_ATCC_199 MSDPSIDMGEHMRRVWELLLR-----------------------------
MMAR_1597|M.marinum_M LATGDRVRIGTALESVIDGIHHQRAQWARVASR-----------------
TH_4317|M.thermoresistible__bu AAVRRVRHLSAAADAVLPEVPVQGRQLGPAQR------------------
Mb0335|M.bovis_AF2122/97 ------------
Rv0328|M.tuberculosis_H37Rv ------------
Mvan_2569|M.vanbaalenii_PYR-1 ------------
MSMEG_1565|M.smegmatis_MC2_155 ------------
MUL_0675|M.ulcerans_Agy99 ------------
Mflv_0941|M.gilvum_PYR-GCK AAPRRTRKKGNR
MAV_3767|M.avium_104 ------------
MAB_3193c|M.abscessus_ATCC_199 ------------
MMAR_1597|M.marinum_M ------------
TH_4317|M.thermoresistible__bu ------------