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LPVARRYDTLLAKGEDRKQRILDVAQRLLTRNGWRNTTLAQIAGEAGVTPAGLLHHFESKEQLLHAVLDA RDLDDDTHADRTGDLFDQIAAVADRFYRAPELVGTFTVLLVENILPEAPLHDRMLARHRAATDIVADLIR RGQADGRYRADIDPAVKAVEILAFVHGMETTWLLDPSIPLPEVFKQYAETLARDFAPPKRAETT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0910 | - | - | 100% (204) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4026 | - | 6e-07 | 27.84% (176) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1141 | - | 2e-06 | 25.88% (170) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 3e-07 | 23.84% (172) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2447 | - | 7e-76 | 72.40% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 3e-07 | 23.84% (172) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 8e-05 | 31.88% (69) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3193c | - | 7e-14 | 27.03% (185) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4739 | - | 3e-90 | 81.82% (198) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4831 | - | 1e-82 | 78.01% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0256 | - | 1e-85 | 80.41% (194) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 7e-09 | 25.75% (167) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 4e-75 | 71.35% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3587c|M.bovis_AF2122/97 ------------------MDRVAGQVNSRRGELLELAAAMFAERGLRATT
Rv3557c|M.tuberculosis_H37Rv ------------------MDRVAGQVNSRRGELLELAAAMFAERGLRATT
MAV_0910|M.avium_104 ------------MPVARRYDTLLAKGEDRKQRILDVAQRLLTRNGWRNTT
MMAR_4739|M.marinum_M ------------MPEVRPYDTLLAKGEDRKQRILGVAQRLLSRNGWRNTT
MSMEG_4831|M.smegmatis_MC2_155 -----MTPPQGQAEAARPYETLLAKGEDRRQRILSVAERLLARNGWRNTS
TH_0256|M.thermoresistible__bu ------------VTQTRPYETLLAKGEDRRQRILAVAERLLARNGWRNTS
Mflv_2447|M.gilvum_PYR-GCK -MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAERLLARNGWRNTS
Mvan_4204|M.vanbaalenii_PYR-1 -MSAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERLLARNGWRSTS
MAB_3193c|M.abscessus_ATCC_199 ------------MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGAS
MUL_4876|M.ulcerans_Agy99 ------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQAS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
: . :: * . . :
Mb3587c|M.bovis_AF2122/97 VRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDST-A
Rv3557c|M.tuberculosis_H37Rv VRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDST-A
MAV_0910|M.avium_104 LAQIAGEAGVTPAGLLHHFESKEQLLHAVLD-ARDLDDDTHADRTGDL-F
MMAR_4739|M.marinum_M LAQIAGEAGVTPAGLLHHFESKEQLLHAVLD-ARDLDDDAHADRLGDL-I
MSMEG_4831|M.smegmatis_MC2_155 LAQIAKEAGVTTAGLLHHFESKEHLLNAVLD-ARDLDDDAHADRSGDL-A
TH_0256|M.thermoresistible__bu LAQIAKEAGVSPAGLLHHFESKEALLNAVLD-ARDADDDAHADRSGDL-I
Mflv_2447|M.gilvum_PYR-GCK LAQIAREAGVTPAGLLHHFESKEQLLNAVLD-ARDADDDAHADRGGDL-V
Mvan_4204|M.vanbaalenii_PYR-1 LAQIAREAGVTPAGLLHHFESKEQLLNAVLD-ARDADDDAHADRSGDL-I
MAB_3193c|M.abscessus_ATCC_199 MRVIAKEANISLAGLMHYFPTRDVILTEIQRGADATFEERYRNSEIEL-D
MUL_4876|M.ulcerans_Agy99 IREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAASS-D
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :* *.: : .:* .:. :: .
Mb3587c|M.bovis_AF2122/97 NPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRF-SYIEDRNKQ
Rv3557c|M.tuberculosis_H37Rv NPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRF-SYIEDRNKQ
MAV_0910|M.avium_104 DQIAAVADRFYRAPELVGTFTVLLVENILPEAPLHDR------MLARHRA
MMAR_4739|M.marinum_M GEIAQVADRFTRAPELVGTFTVLLAENIDPDAPLHDR------LVSRQRD
MSMEG_4831|M.smegmatis_MC2_155 DEIKRVAERFVRAPELVGTFTVLLVENIQPDAPLHDR------LLKRQQD
TH_0256|M.thermoresistible__bu AEIARVAERFDRAPHLVGTFTVLLVENIQPEAPLHDR------MLARQRA
Mflv_2447|M.gilvum_PYR-GCK TELARVPERFERSPELVGTFMVLLAENIAPDAPLHDR------LHKRYRD
Mvan_4204|M.vanbaalenii_PYR-1 AELTRVPKRFERSPELVGTFMVLLAENLAPDAPLHDR------LHQRYRA
MAB_3193c|M.abscessus_ATCC_199 PGEVLAQAMLDKANKPGSGTVYLSLAAAAAVDPEHPAG---AYLRDRYER
MUL_4876|M.ulcerans_Agy99 DIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPGSKA
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVR---RLWSTVMQQ
: . .
Mb3587c|M.bovis_AF2122/97 QRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRWYRPG--GPL
Rv3557c|M.tuberculosis_H37Rv QRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRWYRPG--GPL
MAV_0910|M.avium_104 ATDIVADLIRRGQADGRYRADIDPAVKAVEILAFVHGMETTWLLD--PSI
MMAR_4739|M.marinum_M ACEIVAEAIRRGQEAGRYRADLDPTVKAVEILAFIHGMEMTWLLD--PSI
MSMEG_4831|M.smegmatis_MC2_155 ARDIVADIIRRGQRSGRYRPDFDPVIKAVEILAFVNGMETSWLLD--PSL
TH_0256|M.thermoresistible__bu AIDIVADLIRRGQESGRYRSDFDAATKAVEIIAFVNGMETSWLLD--PSI
Mflv_2447|M.gilvum_PYR-GCK AVDIIEDIITRGQRKGLYRTDFDAASKATEILAFINGMETLWLLD--PSI
Mvan_4204|M.vanbaalenii_PYR-1 AADIIKDLITRGQQKGLYRKDFDAATKATEILAFINGMEIQWLLD--PSI
MAB_3193c|M.abscessus_ATCC_199 MRARIAAYVRGRQVDGTVPAHVDADFAATALIAAADGIQIQWMSD--PSI
MUL_4876|M.ulcerans_Agy99 LRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAANL--GPQ
MLBr_01070|M.leprae_Br4923 WIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLI
: * . :
Mb3587c|M.bovis_AF2122/97 TAQQVGQQYLAIVLGGITKEGV-------
Rv3557c|M.tuberculosis_H37Rv TAQQVGQQYLAIVLGGITKEGV-------
MAV_0910|M.avium_104 PLPEVFKQYAETLARDFAPPKRAETT---
MMAR_4739|M.marinum_M PLTEVFKEYAEALARDFSLP---STT---
MSMEG_4831|M.smegmatis_MC2_155 PLQDVFKGYAEMLAREIELT---------
TH_0256|M.thermoresistible__bu PVAEVFKGYAEMLERDFAPPNPT------
Mflv_2447|M.gilvum_PYR-GCK PLTEVFKGYAESLGRDLAL----------
Mvan_4204|M.vanbaalenii_PYR-1 PLTEVYQGYAESLARDLAAQPSPT-----
MAB_3193c|M.abscessus_ATCC_199 DMGEHMRRVWELLLR--------------
MUL_4876|M.ulcerans_Agy99 SYDVTLDSAKQLLRGSLFAGAKPTATRRT
MLBr_01070|M.leprae_Br4923 PDKKVIDTLVHIWLASIYGS---------