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VTAESDRRSLSFGAEAAAYERGRPSYPPEAIDWLLADSGSRRLEVLDLGAGTGKLTTRLVERGLDVVAVD PIPEMLDLLRTSLPDTPALLGTAEEIPLPDDSVDAVLVAQAWHWFDETRAVKEIARVLRPGGSLGLVWNN RDERLGWVKDLGDIIGHEGDPWSQSVELPAPFTGVERHHVEWTSYLTPQALIDLVASRSYCITSPERVRA RTLDRVRELLTTHPALANSSGLALPYVTVCVRATLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4877 | - | - | 100% (246) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_4060 | - | 3e-09 | 35.29% (119) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_1100 | - | 2e-07 | 29.66% (118) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3374 | - | 1e-107 | 77.64% (246) | methyltransferase (methylase) |
| M. tuberculosis H37Rv | Rv3342 | - | 1e-107 | 77.64% (246) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_01713 | - | 5e-08 | 35.35% (99) | hypothetical protein MLBr_01713 |
| M. abscessus ATCC 19977 | MAB_3689 | - | 1e-102 | 77.31% (238) | putative methyltransferase |
| M. marinum M | MMAR_1183 | - | 1e-107 | 78.46% (246) | methyltransferase |
| M. avium 104 | MAV_4317 | - | 1e-102 | 76.42% (246) | putative methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1650 | - | 1e-112 | 82.92% (240) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_1968 | - | 1e-111 | 82.28% (237) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_1436 | - | 1e-107 | 78.46% (246) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1552 | - | 1e-118 | 86.01% (243) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3374|M.bovis_AF2122/97 ----------MTCS---RRDMSLSFGSAVGAYERGRPSYPPE--------
Rv3342|M.tuberculosis_H37Rv ----------MTCS---RRDMSLSFGSAVGAYERGRPSYPPE--------
MMAR_1183|M.marinum_M ----------MSGS---AQDPSLSFGSAAAAYERGRPSYPPE--------
MUL_1436|M.ulcerans_Agy99 ---------MVSGS---AQDPSLSFGSAAAAYERGRPSYPPE--------
MAV_4317|M.avium_104 ----------MTRS---RHDRSLSFGSAAAAYERGRPSYPPE--------
Mflv_4877|M.gilvum_PYR-GCK ----------MTAE---SDRRSLSFGAEAAAYERGRPSYPPE--------
Mvan_1552|M.vanbaalenii_PYR-1 ----------MTER---PDR-SLSFGAEAAAYERGRPSYPPE--------
TH_1968|M.thermoresistible__bu ----------------------LSFGAEAAAYERGRPSYPPE--------
MSMEG_1650|M.smegmatis_MC2_155 ----------MTPSDPLKQQRSLSFGSEAAAYERGRPSYPPE--------
MAB_3689|M.abscessus_ATCC_1997 ----------MPDA---QAEPSLSFGSQAAAYERGRPSYPPE--------
MLBr_01713|M.leprae_Br4923 MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQ
.* . : ** *. *
Mb3374|M.bovis_AF2122/97 -AIDWLLPAAAR---RVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDV
Rv3342|M.tuberculosis_H37Rv -AIDWLLPAAAR---RVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDV
MMAR_1183|M.marinum_M -AIDWLLPAGAR---DVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLEV
MUL_1436|M.ulcerans_Agy99 -AIDWLLPAGAR---DVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLEV
MAV_4317|M.avium_104 -AIDWLLPVGAR---QVLDLGAGTGKLTTRLVERGLDVVAVDPIPDMLEV
Mflv_4877|M.gilvum_PYR-GCK -AIDWLLADSGSRRLEVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDL
Mvan_1552|M.vanbaalenii_PYR-1 -AIDWLLPEHAH---DVLDLGAGTGKLTTRLAERGLAVVAVDPIPEMLEL
TH_1968|M.thermoresistible__bu -AIDWLLPSDAR---DVLDLGAGTGKLTTRLVERGLNVTAVDPIPEMLEL
MSMEG_1650|M.smegmatis_MC2_155 -AIDWLLPDGAH---DVLDLGAGTGKLTTRLVERGLNVIAVDPLAEMLEL
MAB_3689|M.abscessus_ATCC_1997 -AIDWLLPPGAH---DVLDLGAGTGKLTTRLVERGLNVVAVDPLAEMLEV
MLBr_01713|M.leprae_Br4923 VVYQWLAQRCTG--CEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVAH
. :** **: *.* * : :.: . * *** :
Mb3374|M.bovis_AF2122/97 LRAALPQTVALLGTAEEIPLDDNSVDAVL-VAQAWHWVDPARAIPEVARV
Rv3342|M.tuberculosis_H37Rv LRAALPQTVALLGTAEEIPLDDNSVDAVL-VAQAWHWVDPARAIPEVARV
MMAR_1183|M.marinum_M LRASLPRTLALLGTAEEIPLEDNSVDAVL-VAQAWHWVDPARAIPEVARV
MUL_1436|M.ulcerans_Agy99 LRASLPRTLALLGTAEEIPLEDNSVDAVL-VAQAWHWVDPARAIPEVARV
MAV_4317|M.avium_104 LRSSLPETRALLGTAEEIPLEDNSVDVVL-VAQAWHWVDPERAIPEVARV
Mflv_4877|M.gilvum_PYR-GCK LRTSLPDTPALLGTAEEIPLPDDSVDAVL-VAQAWHWFDETRAVKEIARV
Mvan_1552|M.vanbaalenii_PYR-1 LSTSLPDTPALLGTAEEIPLPDDSVDAVL-VAQAWHWFDPERAVKEVARV
TH_1968|M.thermoresistible__bu LSKSLPDTPALLGTAEEIPLPDNSVDAVL-VAQAWHWFDVDRAVREVARV
MSMEG_1650|M.smegmatis_MC2_155 LSNSLPDTPALLGTAEEIPLPDNSVDAVL-VAQAWHWFDPELAVKEVSRV
MAB_3689|M.abscessus_ATCC_1997 LSNSLPDTPALLGTAEEIPLPDNSVDAVL-VAQAWHWVDPERAIPEVARV
MLBr_01713|M.leprae_Br4923 VRSRYPRVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECARV
: * . .: .. *:** * ***.*: . * : : * :**
Mb3374|M.bovis_AF2122/97 LRPGGRLGLVWNTRDER-LGWVRELGEIIGRDGDPVRDRV-TLPEPFTTV
Rv3342|M.tuberculosis_H37Rv LRPGGRLGLVWNTRDER-LGWVRELGEIIGRDGDPVRDRV-TLPEPFTTV
MMAR_1183|M.marinum_M LRPGGRLGLVWNTRDER-LGWVRELGRIIGRDSDPVRDKV-TLPEPFTGV
MUL_1436|M.ulcerans_Agy99 LRPGGRLGLVWNTRDER-LGWVRELGRIIGRDSDPVRDKV-TLPEPFTGV
MAV_4317|M.avium_104 LRPGGRLGLVWNTRDER-LGWVRELGRIIGSDGD-GRTHV-ALPEPFTDL
Mflv_4877|M.gilvum_PYR-GCK LRPGGSLGLVWNNRDER-LGWVKDLGDIIGHEGDPWSQSV-ELPAPFTGV
Mvan_1552|M.vanbaalenii_PYR-1 LRPGGRLGLVWNNRDER-LGWVKDLGEIIGHEVDPFAQTV-ELPGPFTDV
TH_1968|M.thermoresistible__bu LRPGGRLGLVWNTRDER-MGWVKELGRIIGDEHDPLSKTV-TLPEPFTDV
MSMEG_1650|M.smegmatis_MC2_155 LRPGGRLGLVWNVRDER-LGWVKDLGNIIGHE-DPFAHEV-TLPAPFTDL
MAB_3689|M.abscessus_ATCC_1997 LRPGGRLGLVWNVRDER-LGWVSDLGHIIGHENAADSADVGALPAPFTGQ
MLBr_01713|M.leprae_Br4923 LRPSGLLMVSTPNRITFSPGRDTSINPFHTRELNADELTQLLITADFSEV
***.* * : * * .:. : : :. *:
Mb3374|M.bovis_AF2122/97 QRH------QVEWTNYLTPQALIDLVASRSYC--------ITSPAQVRTK
Rv3342|M.tuberculosis_H37Rv QRH------QVEWTNYLTPQALIDLVASRSYC--------ITSPAQVRTK
MMAR_1183|M.marinum_M ARH------HVEWTNYLTPQALIDLVASRSYC--------ITSPAEVRTK
MUL_1436|M.ulcerans_Agy99 ARH------HVEWTNYLTPQALIDLVASRSYC--------ITSPAEVRTK
MAV_4317|M.avium_104 AHH------EVEWTNYLTPQALIDLVASRSYC--------ITSPTEVRTR
Mflv_4877|M.gilvum_PYR-GCK ERH------HVEWTSYLTPQALIDLVASRSYC--------ITSPERVRAR
Mvan_1552|M.vanbaalenii_PYR-1 EHH------RVEWTSYLTPQALIDLVASRSYC--------ITSPEQVRAR
TH_1968|M.thermoresistible__bu QRH------QVEWTNYLTPQALIDLVASRSYC--------ITSPAKVRAR
MSMEG_1650|M.smegmatis_MC2_155 ERH------HVEWTSYLTPQALIDLVASRSYC--------ITSPEQVRTR
MAB_3689|M.abscessus_ATCC_1997 ERH------QVEWTNYLTPQALLDMVASRSYC--------ITAPEAARKK
MLBr_01713|M.leprae_Br4923 AMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVADVAAVTAA
: .:: . :::* :*: . :: .
Mb3374|M.bovis_AF2122/97 TLDRVRQLLATHPALANSNGLALPYVTVCVRATLA-
Rv3342|M.tuberculosis_H37Rv TLDRVRQLLATHPALANSNGLALPYVTVCVRATLA-
MMAR_1183|M.marinum_M TLDQVRELLATHPALANSAGLALPYVTVCVSATLAA
MUL_1436|M.ulcerans_Agy99 TLDQVRELLATHPALANSAGLALPYVTVCVSATLAA
MAV_4317|M.avium_104 TLDQVRHLLATHPALANSTGLALPYVTRCTRATLAG
Mflv_4877|M.gilvum_PYR-GCK TLDRVRELLTTHPALANSSGLALPYVTVCVRATLA-
Mvan_1552|M.vanbaalenii_PYR-1 TLDRVRELLATHPALASSSGLALPYVTVCTRATLS-
TH_1968|M.thermoresistible__bu TLERVRELLATHPALANNSGLALPYITVCIRATLA-
MSMEG_1650|M.smegmatis_MC2_155 TLGQVRELLSTHPALANSNGLALPYVTVCMRATLA-
MAB_3689|M.abscessus_ATCC_1997 TLQQVRELLATHPALAQSAGLALPYVTVSIRATLNR
MLBr_01713|M.leprae_Br4923 DFDIIEASAGPEASDGRDVDESLDLIAIAVRR----
: :. ...: . . . :* :: .