For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSMDHMTENPPHPVARTWGNRHDYLPAAGRDFFLPAYDLLVRLLGTYPLYDELVTQAELAGELDVLEIGC GTGNLTARALRAAPSARITATDPDPRAVTRARRKAAGEGPVRFETAYAQELPFADASFDRVLSSLMLHHL DDGTKVSALAEAWRVLRPGGRLHIVDVGGADQPEGLMSRLTGHRHAAAGARLPQLVEAAGFDTTVVATRR LRVFGPVSFIRATRPGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5517 | - | - | 100% (228) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_4620 | - | 8e-13 | 32.99% (194) | methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_3244 | - | 1e-11 | 41.12% (107) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1440c | - | 5e-12 | 31.68% (161) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_4269 | - | 6e-10 | 37.11% (97) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1405c | - | 5e-12 | 31.68% (161) | putative methyltransferase |
| M. leprae Br4923 | MLBr_01723 | - | 3e-10 | 36.08% (97) | hypothetical protein MLBr_01723 |
| M. abscessus ATCC 19977 | MAB_4103c | - | 1e-11 | 37.01% (127) | methyltransferase |
| M. marinum M | MMAR_1062 | - | 3e-57 | 53.12% (224) | methyltransferase |
| M. avium 104 | MAV_3373 | - | 1e-14 | 34.78% (161) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_0098 | - | 4e-12 | 34.36% (163) | methyltransferase |
| M. thermoresistible (build 8) | TH_3395 | - | 2e-11 | 33.54% (158) | PUTATIVE putative ubiquinone/menaquinone biosynthesis |
| M. ulcerans Agy99 | MUL_0820 | - | 4e-57 | 54.98% (211) | methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1062|M.marinum_M -------MTNHHPRFGLQHSGESRDYLPAAGHDALLPAYDLLSRLLGMNK
MUL_0820|M.ulcerans_Agy99 -------MTNHHPRFGLQHSGESRDYLPAAGHDALLPAYDLLSRLLGMNK
Mvan_5517|M.vanbaalenii_PYR-1 -MVSMDHMTENPPHPVARTWGNRHDYLPAAGRDFFLPAYDLLVRLLGTYP
Mb1440c|M.bovis_AF2122/97 ---------------MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMA
Rv1405c|M.tuberculosis_H37Rv ---------------MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMA
MAV_3373|M.avium_104 ---------------MTLDTTT-ADASVAARHRTVWALGDYALMAEEVMA
Mflv_4269|M.gilvum_PYR-GCK MTETKEPGAYPDVAVPAPTPHATKEQVEAALHDTKLAQVLYHDWEAETYD
MLBr_01723|M.leprae_Br4923 MTRSTEISAN-----AVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYD
TH_3395|M.thermoresistible__bu ------MADVAANWAGRGGRFAGGLYDFGVEREVLARPAGLLMWGTDTRL
MSMEG_0098|M.smegmatis_MC2_155 -MDTALRRAMDLLIDPPAEPDFSKGYLDLLGRGDSTAPKNTGLIQKAWAS
MAB_4103c|M.abscessus_ATCC_199 --MQRSRDWVMFKLNAVFTQRVQKFIYRHATRKLETEDVVFLNYGYEEEP
:
MMAR_1062|M.marinum_M IHRTLITQAELAD-------------------CGRILEIGCGTGNLAIKA
MUL_0820|M.ulcerans_Agy99 IHRTLITQAELAD-------------------CGRILEIGCGTGNLAIKA
Mvan_5517|M.vanbaalenii_PYR-1 LYDELVTQAELAG-------------------ELDVLEIGCGTGNLTARA
Mb1440c|M.bovis_AF2122/97 PLGPILVAAAGIG------------------PGVRVLDVAAGSGNISLPA
Rv1405c|M.tuberculosis_H37Rv PLGPILVAAAGIG------------------PGVRVLDVAAGSGNISLPA
MAV_3373|M.avium_104 PLGPTLVEAAGIG------------------PGVRVLDVAAGSGNITLPA
Mflv_4269|M.gilvum_PYR-GCK DKWSISYDQRCVDYARGRFDAAVPEEVQRELPYDRALELGCGTGFFLLNL
MLBr_01723|M.leprae_Br4923 EKWSISYDQRCVDYVRHCFDAIVPDELFTELPYDCALELGCGTGFFLLNL
TH_3395|M.thermoresistible__bu LFDSIRRIGDLPD-------------------GTAVLDIPCGGG-LALRG
MSMEG_0098|M.smegmatis_MC2_155 PLGSKLYDRAQLLNRRLVASTRPPVEWLRIPPGGTVLDIGCGPGNITAQL
MAB_4103c|M.abscessus_ATCC_199 AMGVPLSASDEPD--RYSIQLYHSTATQADLGGQRVLEVGCGHGGGASYL
*:: .* *
MMAR_1062|M.marinum_M KRAQ-PRAEVIGSDPDPRALQRAQRKTGNV--EGVRFDQGYAQRLPYADG
MUL_0820|M.ulcerans_Agy99 KRAQ-PRAEVIGSDPDPRALQRAQRKTGNV--EEVRFDQGYAQRLPYADG
Mvan_5517|M.vanbaalenii_PYR-1 LRAA-PSARITATDPDPRAVTRARRKAAGE--GPVRFETAYAQELPFADA
Mb1440c|M.bovis_AF2122/97 AKTG-ATVIS--TDLTPELLQRSQARAAQQG-LTLQYQEANAQALPFADD
Rv1405c|M.tuberculosis_H37Rv AKTG-ATVIS--TDLTPELLQRSQARAAQQG-LTLQYQEANAQALPFADD
MAV_3373|M.avium_104 AAAG-ASVVS--TDLTPELLQRSRDRAAGMG-LTIDYREANAQALPFGDG
Mflv_4269|M.gilvum_PYR-GCK IQAG-VARRGSVTDLSPGMVKVATRNGQSLG-LDIDGRVADAEGIPYEDN
MLBr_01723|M.leprae_Br4923 IQSG-VARRGSVTDLSPGMVKIATRNGQSLG-LDINGRVADAEGIPYDDN
TH_3395|M.thermoresistible__bu LRHG-RRLRYVAADISADMLARAQRRAATLGRTDVRFVVADIERMPFGDG
MSMEG_0098|M.smegmatis_MC2_155 ARAAGLDGLALGVDISEPMLARAVAAEAGR---QVGFVRADAQQLPFRDE
MAB_4103c|M.abscessus_ATCC_199 VRAL-QPASYTGLDLNPDGISFCRRRHDLPG---LEFVQGDAEDLPFPDE
* : . : . : :*: *
MMAR_1062|M.marinum_M EFDRVLSSMMLHHLDEDAKSAAAAEAFRVLRPGGRLHLVDVGGDMSAHDG
MUL_0820|M.ulcerans_Agy99 EFDRVLSSMMLHHLDEDAKSAAAAEAFRVLRPGGRLHLVDVGGDMSAHDG
Mvan_5517|M.vanbaalenii_PYR-1 SFDRVLSSLMLHHLDDGTKVSALAEAWRVLRPGGRLHIVDVGG-ADQPEG
Mb1440c|M.bovis_AF2122/97 EFDTVISAIGVMFAPD--HQAAADELVRVCRPGGTIGVISWTCEG--FFG
Rv1405c|M.tuberculosis_H37Rv EFDTVISAIGVMFAPD--HQAAADELVRVCRPGGTIGVISWTCEG--FFG
MAV_3373|M.avium_104 EFDAVVSAIGVQFAPD--HQRAADELVRVCRPGGRIGLISWTPEG--FFG
Mflv_4269|M.gilvum_PYR-GCK TFDLVVGHAVLHHIPD--VELSLREVVRVLKPGGRFVFAGEPTTVGNRYA
MLBr_01723|M.leprae_Br4923 TFDLVVGHAVLHHIPD--VELSLREVLRVLKPGGRFVFAGEPTDVGNRYA
TH_3395|M.thermoresistible__bu EFDCCVTFNGLHCVPD--PAAAVAEIARCVKPGGRLIGDAVVRGAGRRQD
MSMEG_0098|M.smegmatis_MC2_155 VFDAATSLAVFQLIPD--PVAAVSEIVRVLKPGGRVAIMVPTAGAVKPVT
MAB_4103c|M.abscessus_ATCC_199 SFDAVINVESSHLYPH--FPVFLTEVARVLRPGGNFLYTDARSVQDVAGW
** . * * :*** .
MMAR_1062|M.marinum_M LASRFIRHN----------------------LHVAGNLGDGIRRLLDTAG
MUL_0820|M.ulcerans_Agy99 LASRFIRHN----------------------LHVAGNLGDGIRRLLDTAG
Mvan_5517|M.vanbaalenii_PYR-1 LMSRLTGHR----------------------HAAAG---ARLPQLVEAAG
Mb1440c|M.bovis_AF2122/97 RMLATIRPYRPSVSADLPPSALWGRE-----AYVTGLLGDGVTGLKTAR-
Rv1405c|M.tuberculosis_H37Rv RMLATIRPYRPSVSADLPPSALWGRE-----AYVTGLLGDGVTGLKTAR-
MAV_3373|M.avium_104 RMLATIRPYRPSLSHPVPPAALWGRP-----GYVRALLGERIGEITTAR-
Mflv_4269|M.gilvum_PYR-GCK RELSTLTWHAATNIMKLPMLSDWRRPQAELDESSRAAALEAVVDLHTFDP
MLBr_01723|M.leprae_Br4923 RVFADLTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLHTFEP
TH_3395|M.thermoresistible__bu ALIAVFRRAG---------------------VFGPGGTTDELQGWLTRAG
MSMEG_0098|M.smegmatis_MC2_155 FLAR---------------------------GGARIFGDDELGDIFENVG
MAB_4103c|M.abscessus_ATCC_199 KVALANAPLR---------------------MVSERGINAEVRRGMEKNL
:
MMAR_1062|M.marinum_M FDVAEVGAQRHPLLGRLVYYRATRPCA-----------------------
MUL_0820|M.ulcerans_Agy99 FDVAEVGAQRHPLLGRLVYYRATRPCA-----------------------
Mvan_5517|M.vanbaalenii_PYR-1 FDTTVVATRRLRVFGPVSFIRATRPGE-----------------------
Mb1440c|M.bovis_AF2122/97 -GLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIGDNAVLAAELDRQLVEL
Rv1405c|M.tuberculosis_H37Rv -GLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIGDNAVLAAELDRQLVEL
MAV_3373|M.avium_104 -GMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIGHNRVLAAELDAQLVEL
Mflv_4269|M.gilvum_PYR-GCK ADLERMAANAGAVEVRTASEEFTAAMLGWPVRTFEAAVPPGRLGWGWAKF
MLBr_01723|M.leprae_Br4923 KVLETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLGWGWARF
TH_3395|M.thermoresistible__bu FEVEDFRRSGAVAHFTAVRS------------------------------
MSMEG_0098|M.smegmatis_MC2_155 LVGVRVKTHGFIQWVRGTKL------------------------------
MAB_4103c|M.abscessus_ATCC_199 ARWRYVIDRATPAPLRGIVRRFAPAQRAYDDLRAGGSVEYRMYRFVKA--
.
MMAR_1062|M.marinum_M ------------------------------------
MUL_0820|M.ulcerans_Agy99 ------------------------------------
Mvan_5517|M.vanbaalenii_PYR-1 ------------------------------------
Mb1440c|M.bovis_AF2122/97 AAQYLSDG------------VMEWEYLLLTAEKR--
Rv1405c|M.tuberculosis_H37Rv AAQYLSDG------------VMEWEYLLLTAEKR--
MAV_3373|M.avium_104 AAQHLSDG------------TMGWEYLLVTAEKRSG
Mflv_4269|M.gilvum_PYR-GCK AFGSWTTLSWVDANVWRRIVPKGWFYNVMVTGVKPS
MLBr_01723|M.leprae_Br4923 AFTSWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
TH_3395|M.thermoresistible__bu ------------------------------------
MSMEG_0098|M.smegmatis_MC2_155 ------------------------------------
MAB_4103c|M.abscessus_ATCC_199 ------------------------------------