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LLQHLDYLLALAAERHFGRAAARCHVSQPTLSVAIRRLERDLGIVIVQRGHRFEGFTEEGRRVVTWAQRI IAERDEMLADLERMRGRLTVTARVGAIPTAVPASPFITAEFLHRNPAASVRIEALSSREIARRLADFEID AGLTYLDDEAPPGTRSVELYREQYVLVAPHDHRLMEHTEVTWTDAAAMELCVLTTTMRNRRILDANMAAE GVSYRPAVEADSVDALYAHLTHSRRATIASTAWLPQLGVPQGFAARPMVQHGPRPAIGLVVLDRAPASIV AAALVAVAADIDLGSRIDSMWSEMTAVTRGPRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4031 | - | - | 100% (314) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4734 | - | 7e-17 | 27.20% (261) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 8e-15 | 26.58% (222) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 3e-54 | 38.10% (315) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_2595 | - | 1e-147 | 85.81% (303) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 3e-54 | 38.10% (315) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02663 | oxyS | 3e-54 | 38.06% (310) | putative LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0998 | - | 2e-49 | 38.83% (291) | LysR family transcriptional regulator |
| M. marinum M | MMAR_0317 | oxyS | 1e-54 | 38.72% (297) | oxidative stress response regulatory protein OxyS |
| M. avium 104 | MAV_5191 | - | 5e-57 | 38.26% (311) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_4667 | - | 1e-146 | 84.59% (305) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 5e-06 | 23.63% (182) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4805 | oxyS | 2e-50 | 40.65% (246) | oxidative stress response regulatory protein OxyS |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2595|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4667|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4031|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0317|M.marinum_M MKLLGAPKINPELTLAQIPGSDSLVVIPIPRTSGLARRAAPAVQPRCGVT
MUL_4805|M.ulcerans_Agy99 --------------------------------------------------
Mb0121|M.bovis_AF2122/97 --------------------------------------------------
Rv0117|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02663|M.leprae_Br4923 --------------------------------------------------
MAV_5191|M.avium_104 --------------------------------------------------
MAB_0998|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3504|M.thermoresistible__bu --------------------------------------------------
Mflv_2595|M.gilvum_PYR-GCK -----------------------------------------MANDVLLQH
MSMEG_4667|M.smegmatis_MC2_155 -----------------------------------------MASDVMLQH
Mvan_4031|M.vanbaalenii_PYR-1 ---------------------------------------------MLLQH
MMAR_0317|M.marinum_M RTAQWRADLVATVQDLAAQSGTGGRQRSGGGGSLSESVPMTEEVSVLFRQ
MUL_4805|M.ulcerans_Agy99 ---------------------------------------------MLFRQ
Mb0121|M.bovis_AF2122/97 ---------------------------------------------MLFRQ
Rv0117|M.tuberculosis_H37Rv ---------------------------------------------MLFRQ
MLBr_02663|M.leprae_Br4923 ---------------------------------------------MLFRQ
MAV_5191|M.avium_104 ---------------------------------------------MLFRQ
MAB_0998|M.abscessus_ATCC_1997 ---------------------------------------------MQFRQ
TH_3504|M.thermoresistible__bu ----------------------------------------VPSPKIDLRR
: :::
Mflv_2595|M.gilvum_PYR-GCK LDYLLALAAERHFGRAAARCHVSQPTLSVAIRRLERDLGIVIVQRGHRFE
MSMEG_4667|M.smegmatis_MC2_155 LDYLLALASERHFGRAAARCHVSQPTLSVAIRRLERDLGITIVQRGQRFE
Mvan_4031|M.vanbaalenii_PYR-1 LDYLLALAAERHFGRAAARCHVSQPTLSVAIRRLERDLGIVIVQRGHRFE
MMAR_0317|M.marinum_M LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFE
MUL_4805|M.ulcerans_Agy99 LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELHVTLINRGHSFE
Mb0121|M.bovis_AF2122/97 LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFE
Rv0117|M.tuberculosis_H37Rv LEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFE
MLBr_02663|M.leprae_Br4923 LEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNVTLINRGHSFE
MAV_5191|M.avium_104 LEYFVAVASERHFARAAEKCFVSQPALSAAIAKLEKELNVTLINRGHSFE
MAB_0998|M.abscessus_ATCC_1997 LEYFVALARERHFARAASACYVSQPALSEAIRKLEHELGVPLVLRGSNFE
TH_3504|M.thermoresistible__bu LAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDVGADLFTRDGRRI
* ::*:* * *** .:** :** *: **.:: :. *.
Mflv_2595|M.gilvum_PYR-GCK GFTVEGQRVVTWAQRIVAERDEMLADLDRMQGRLTASARLGAIPTAVPVC
MSMEG_4667|M.smegmatis_MC2_155 GFTEEGRRVVTWAQRIVAERDEMLADIERMQGRLTATARIGAIPTAVPAS
Mvan_4031|M.vanbaalenii_PYR-1 GFTEEGRRVVTWAQRIIAERDEMLADLERMRGRLTVTARVGAIPTAVPAS
MMAR_0317|M.marinum_M GLTPEGERLVVWAKRIIAEHDAFKAEVDAVRSGITGTLRLGTVPSASTTA
MUL_4805|M.ulcerans_Agy99 GLTPEGERLVVWAKRIIAEHDAFKAEVDAVRSGITGTLRLGTVRSASTTA
Mb0121|M.bovis_AF2122/97 GLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLGTVPTASTTA
Rv0117|M.tuberculosis_H37Rv GLTREGERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLGTVPTASTTA
MLBr_02663|M.leprae_Br4923 GLTPEGERLVVWAKRILAEHDAFKAEVHAVRSGITGTLRLGTVPTASTTA
MAV_5191|M.avium_104 GLTPEGERLVVWARRILAEHDAFKAEVDAVRSGVTGTLRLGTVPTASTTA
MAB_0998|M.abscessus_ATCC_1997 GLTPEGDRLVLWARRILADRDALEHEVTALRSGLTGELRLGVVPGAATRV
TH_3504|M.thermoresistible__bu SLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHYVIGHTPALSGAE
.:* * :: .: ::* . .: .. :*
Mflv_2595|M.gilvum_PYR-GCK PFITDEFLRRNPAAAVRIEA-LSSREIARRLADFEIDVGLTY-LDDEAPP
MSMEG_4667|M.smegmatis_MC2_155 PFVTDEFLRRNPAASVRIEA-LSSREIARRLADFEIDGGLTY-LDEETPP
Mvan_4031|M.vanbaalenii_PYR-1 PFITAEFLHRNPAASVRIEA-LSSREIARRLADFEIDAGLTY-LDDEAPP
MMAR_0317|M.marinum_M SLVLSDFCSAHPLVKAQICSRLAVTELYRRLRDFELDAAIVY-TSSDDGH
MUL_4805|M.ulcerans_Agy99 SLVLSDFCSAHPLVKAQICSRLAVTELYRRLRDFERDAAIVY-TSSDDGH
Mb0121|M.bovis_AF2122/97 SLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELDAVIVH-PETQDSD
Rv0117|M.tuberculosis_H37Rv SLVLSAFCSAHPLAKVQVCSRLAATELYRRLREFELDAVIVH-PETQDSD
MLBr_02663|M.leprae_Br4923 SLVLSAFCSEHPLIKVQICSRLPVTELHRRLGDFELDAVIVH-SAPDDTH
MAV_5191|M.avium_104 SLLLSAFCSAHPLVKVQILSRLSAGELYRRLREFELDAAIAH-TAPDDIP
MAB_0998|M.abscessus_ATCC_1997 ALMADALCAEHPLVRVRIESSLRSVEILDRIRRFELDAGVVY-DDGLQTD
TH_3504|M.thermoresistible__bu AYALIEPAVTAYPSTSFTLRQLYPDALTDAVFDGTVQLGLRRGVVPTPEL
. * : : : :
Mflv_2595|M.gilvum_PYR-GCK GTRAVELYREQYVLVAPADNPLMGLDEVAWSDAAGLQLCVLTTSMRNRRI
MSMEG_4667|M.smegmatis_MC2_155 GTRSVELYREQYVLVAPGDDPLMGESPVSWSDAAGRPLCMLTTAMRNRRI
Mvan_4031|M.vanbaalenii_PYR-1 GTRSVELYREQYVLVAPHDHRLMEHTEVTWTDAAAMELCVLTTTMRNRRI
MMAR_0317|M.marinum_M DVDLVPLYEERYVLLAPPEMLPPGVSTLSWLDAAQLPLALLSSDMRDRQI
MUL_4805|M.ulcerans_Agy99 DVDLVPLYEERYVLLAPPEMLPPGVSTLSWLDAAQLPLALLSSDMRDRQI
Mb0121|M.bovis_AF2122/97 DVDLVPLYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMRDRQV
Rv0117|M.tuberculosis_H37Rv DVDLVPLYEEQYVLLSPADMLPPGTSTLVWRDAAQLPLALLTADMRDRQV
MLBr_02663|M.leprae_Br4923 AVDLVPLYHEHYVLVSPADMLPPGASVLAWPEASQLPLALLTPDMRDRQL
MAV_5191|M.avium_104 DVNLVPVYRERYVLLAPADLLASGAATMTWVQAAQLPLALLTPDMRDRQI
MAB_0998|M.abscessus_ATCC_1997 GLELTRLYEERYVLVAGDGLLRDAHDPIDWSEALSLPMCLLHKGMRDRDR
TH_3504|M.thermoresistible__bu ATAVIGYHRVRVAFVDSHPLAARESVDITELAREQVALWAPPGTSYYSDF
:. : .:: : :
Mflv_2595|M.gilvum_PYR-GCK LDANMAAEGIRYRPVVEADSVDALYAHLTGSHRATIASTAWLPKLG----
MSMEG_4667|M.smegmatis_MC2_155 LDANMAAEGAQYRPVVEADSVDALYAHLISSKRATIASTAWLPQLG----
Mvan_4031|M.vanbaalenii_PYR-1 LDANMAAEGVSYRPAVEADSVDALYAHLTHSRRATIASTAWLPQLG----
MMAR_0317|M.marinum_M IDAAFADHAITVSPQVETDSVASLFAQVATGNSASIVPHTWLWTT----P
MUL_4805|M.ulcerans_Agy99 IDAAFADHAITVSPQVETDSVASLFAQVATGNSASIVPHTWLWTT----P
Mb0121|M.bovis_AF2122/97 IDAAFADHAVSAIPQVETDSVASLFAQVATGNWASIVPHTWLWAMPMSGP
Rv0117|M.tuberculosis_H37Rv IDAAFADHAVSAIPQVETDSVASLFAQVATGNWASIVPHTWLWAMPMSGP
MLBr_02663|M.leprae_Br4923 IDRAFAGHAITATPQVETDSVASLFAQVATGNWACIVPHTWLWTT----P
MAV_5191|M.avium_104 IDRAFADHGITLHPQVETDSVASLFAQASAGSWASIVPHTWLWAS----P
MAB_0998|M.abscessus_ATCC_1997 IDEAAAEHGLAVSPRLEADSVATLLALVGTGRWAAIVARTWFATA----A
TH_3504|M.thermoresistible__bu LMGACRRAGFEPDYVVSRVQGAATVAAPLTTGGIAFVTAAAGPTMN----
: . :. . : * :.. :
Mflv_2595|M.gilvum_PYR-GCK LPQGFGARPMVRHGPRPPIGLVVLDRAPASIVAAALVEVAGELDLGVRID
MSMEG_4667|M.smegmatis_MC2_155 IPEGFAARPMVQHGPSPAIGLVVLDRAPASIVAAALAEVAEGIDLSTRID
Mvan_4031|M.vanbaalenii_PYR-1 VPQGFAARPMVQHGPRPAIGLVVLDRAPASIVAAALVAVAADIDLGSRID
MMAR_0317|M.marinum_M AGGEIRPVQLVSPVVKAQVALATSSTGPGSPVARALMTSAQGLALDEFFQ
MUL_4805|M.ulcerans_Agy99 GR------------------------------------------------
Mb0121|M.bovis_AF2122/97 TGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALNEFFD
Rv0117|M.tuberculosis_H37Rv TGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALNEFFD
MLBr_02663|M.leprae_Br4923 IGAEIRAVEMVDPVLKADVALATNSAGPGSPVARALVASAKQLALNEFFE
MAV_5191|M.avium_104 LGPGIRAVELVDPVLTADVVLAIKSHGPGSPIARALAASAGRLQLNDFFD
MAB_0998|M.abscessus_ATCC_1997 PPAGTRTVELQAPTLGSPVALVRAAGDPASLLARALAQVVAPPDQP----
TH_3504|M.thermoresistible__bu --GRVQVVDLTPPLLVP--VQALWQRHTLSAIRDRILEGLG---------
Mflv_2595|M.gilvum_PYR-GCK RMWSAAAL-------
MSMEG_4667|M.smegmatis_MC2_155 RMWADMRPS------
Mvan_4031|M.vanbaalenii_PYR-1 SMWSEMTAVTRGPRR
MMAR_0317|M.marinum_M TRLMEISRRR-----
MUL_4805|M.ulcerans_Agy99 ---------------
Mb0121|M.bovis_AF2122/97 TQLRGITRRR-----
Rv0117|M.tuberculosis_H37Rv TQLRGITRRR-----
MLBr_02663|M.leprae_Br4923 AQLAGITRRR-----
MAV_5191|M.avium_104 AQLLGVTRRR-----
MAB_0998|M.abscessus_ATCC_1997 ---------------
TH_3504|M.thermoresistible__bu ---------------