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VSRIEADTREHLLTVAERLFLDAGYENVSVRAVCATAGVNPAAVHYHFGSKVGLVSALLEARLGPLWEDA LTEAAGEGPAGISDAVRIVVEPLVELAGDPAGRLYLHLLSRLLLARVELSWTRRWFAVAPWVALLRRHLP ELSERDAEARWMLAFELIFTQFGDPLAGDRRLSARRVQTLQAFVAAGLSAPVESR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2880 | - | - | 100% (195) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 7e-10 | 42.62% (61) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 2e-07 | 38.03% (71) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 4e-09 | 30.62% (209) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2447 | - | 6e-08 | 44.64% (56) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 4e-09 | 30.62% (209) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-05 | 34.85% (66) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0835c | - | 2e-13 | 39.82% (113) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5193 | - | 2e-11 | 41.35% (104) | hypothetical protein MMAR_5193 |
| M. avium 104 | MAV_3088 | - | 3e-08 | 42.37% (59) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 3e-09 | 42.62% (61) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_0256 | - | 2e-08 | 39.44% (71) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4890 | - | 3e-10 | 32.76% (116) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2534|M.bovis_AF2122/97 --------------MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAER
Rv2506|M.tuberculosis_H37Rv --------------MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAER
MAV_3088|M.avium_104 --------------MTTT---GTTRR---RRGRPAGSSGSRERILASARE
MSMEG_3765|M.smegmatis_MC2_155 --------------MTATSDTGRARK---RPGRPPGASDTRDRILASARE
Mflv_2447|M.gilvum_PYR-GCK ------------MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAER
TH_0256|M.thermoresistible__bu -----------------------VTQTRPYETLLAKGEDRRQRILAVAER
MMAR_5193|M.marinum_M ------------------------MNYSRARGRRAGKPDTRAKILEVARR
MAB_0835c|M.abscessus_ATCC_199 ------------------------MTDTSAETTILTEDSTDQRLLNAAER
Mvan_2880|M.vanbaalenii_PYR-1 --------------------------------MSRIEADTREHLLTVAER
MUL_4890|M.ulcerans_Agy99 -------------------------MESKRRTQEERSAATREALITAARK
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
:: *
Mb2534|M.bovis_AF2122/97 LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL-
Rv2506|M.tuberculosis_H37Rv LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL-
MAV_3088|M.avium_104 LFARNGIRNTSIRAVAAAAGVDSALVHHYFGTKEKLFAAAVQIPIDPMQ-
MSMEG_3765|M.smegmatis_MC2_155 LFARNGFDKTSIRAVAAGADVDPALVHHYFGTKTQLFAAAIHIPIDPLE-
Mflv_2447|M.gilvum_PYR-GCK LLARNGWRNTSLAQIAREAGVTPAGLLHHFESKEQLLNAVLDARDADDD-
TH_0256|M.thermoresistible__bu LLARNGWRNTSLAQIAKEAGVSPAGLLHHFESKEALLNAVLDARDADDD-
MMAR_5193|M.marinum_M RFLEGGYQGVKLRSVAAEAGVDLALISYYFGSKRGLVGEALALSANPAD-
MAB_0835c|M.abscessus_ATCC_199 LFAERGVDAVSLRAIMAAAGTNVASVHYHFGSKERLIEALLDRYLDQIEK
Mvan_2880|M.vanbaalenii_PYR-1 LFLDAGYENVSVRAVCATAGVNPAAVHYHFGSKVGLVSALLEARLGPLWE
MUL_4890|M.ulcerans_Agy99 LWGSRGYAEVGTPEIAAEAGVTRGAMYHQFADKAALFGEVVEAVEQDVMT
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
* . : *.. : * * * :
Mb2534|M.bovis_AF2122/97 -------AGARDVT--TRSANLAAALDGLIEFHLDFALGEADLIRIQDRD
Rv2506|M.tuberculosis_H37Rv -------AGARDVT--TRSANLAAALDGLIEFHLDFALGEADLIRIQDRD
MAV_3088|M.avium_104 -------VIGPLRE--VPVDDLGYALPSMLLPLWDSEVGAAFIATLR---
MSMEG_3765|M.smegmatis_MC2_155 -------VIGPLRE--VPVEQIGHTLPRLLLPLWDSELGKGFIATLR---
Mflv_2447|M.gilvum_PYR-GCK -------AHADRGG--DLVTELARVPERFERS--PELVGTFMVLLAENIA
TH_0256|M.thermoresistible__bu -------AHADRSG--DLIAEIARVAERFDRA--PHLVGTFTVLLVENIQ
MMAR_5193|M.marinum_M -------VLDQAVAKGDPATFPQRVLAGLLALWEDPASGASLRALVAG--
MAB_0835c|M.abscessus_ATCC_199 RRFALLDVAETARTLRAIAEAIVTPLSEIAEEGSTAWLSTLGKLLISGHP
Mvan_2880|M.vanbaalenii_PYR-1 D-----ALTEAAGEGPAGISDAVRIVVEPLVELAGDPAGRLYLHLLSR--
MUL_4890|M.ulcerans_Agy99 R----MATSVTTSGAATPADAIRAAVDAWLEVSGDPEVRQLILLDAP---
MLBr_00815|M.leprae_Br4923 S------VQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDN--
Mb2534|M.bovis_AF2122/97 LAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLL
Rv2506|M.tuberculosis_H37Rv LAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLL
MAV_3088|M.avium_104 -SILAGEEISLFRTFIQDVIGVEVGPRVDNPAGSGVIRIQFVASQLVGVV
MSMEG_3765|M.smegmatis_MC2_155 -SILAGNDVSLVRSFLQEVIVGEVGSRVDNPAGSGRIRVQYVASQLVGVV
Mflv_2447|M.gilvum_PYR-GCK PDAPLHDRLHKRYRDAVDIIEDIITRGQRKGLYRTDFDAASKATEILAFI
TH_0256|M.thermoresistible__bu PEAPLHDRMLARQRAAIDIVADLIRRGQESGRYRSDFDAATKAVEIIAFV
MMAR_5193|M.marinum_M -AAHDPALANRVKEMVERELIDKIAAQLSG--TDARKRASMFCSQIAGLI
MAB_0835c|M.abscessus_ATCC_199 ALIPMSVSFQPQAARLQELILRLRPDATLPSIRFGVTHAVTLTCVVLGDI
Mvan_2880|M.vanbaalenii_PYR-1 ---LLLARVELSWTRRWFAVAPWVALLRRHLPELSERDAEARWMLAFELI
MUL_4890|M.ulcerans_Agy99 -AVLGWAGFCDVAQRYSLGMTEQLITEAIRAGQLDRHPVRPLAHVLIGAL
MLBr_00815|M.leprae_Br4923 ---ITEPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGIS
Mb2534|M.bovis_AF2122/97 NS-TPHSMKAADSKPARTVRARAVLRAMTVAALSAADRCL----------
Rv2506|M.tuberculosis_H37Rv NS-TPHSMKAADSKPARTVRARAVLRAMTVAALSAADRCL----------
MAV_3088|M.avium_104 MARYILELEPFASLPPEQIAATIAPNLQRYLTGDLPDGLAP---------
MSMEG_3765|M.smegmatis_MC2_155 MARYILELEPFKSLPVEQIAETIGPNLQRYLTGELPGFGALD--------
Mflv_2447|M.gilvum_PYR-GCK NGMETLWLLDP-SIPLTEVFKGYAESLGRDLAL-----------------
TH_0256|M.thermoresistible__bu NGMETSWLLDP-SIPVAEVFKGYAEMLERDFAPPNPT-------------
MMAR_5193|M.marinum_M VTRYILCLEPACSMTHDEIIRQYAPLLHLALRSTTATARRPAPNTLSGNT
MAB_0835c|M.abscessus_ATCC_199 AHTNRLMSLSGTYLDDGQMNAQLIDMVTAILAGPPDES------------
Mvan_2880|M.vanbaalenii_PYR-1 FTQFGDPLAGDRRLSARRVQT-LQAFVAAGLSAPVESR------------
MUL_4890|M.ulcerans_Agy99 DEAAMFIATADDPKRARRESRQVLRRLIDGMLND----------------
MLBr_00815|M.leprae_Br4923 VDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-----------
Mb2534|M.bovis_AF2122/97 ---
Rv2506|M.tuberculosis_H37Rv ---
MAV_3088|M.avium_104 ---
MSMEG_3765|M.smegmatis_MC2_155 ---
Mflv_2447|M.gilvum_PYR-GCK ---
TH_0256|M.thermoresistible__bu ---
MMAR_5193|M.marinum_M TGR
MAB_0835c|M.abscessus_ATCC_199 ---
Mvan_2880|M.vanbaalenii_PYR-1 ---
MUL_4890|M.ulcerans_Agy99 ---
MLBr_00815|M.leprae_Br4923 ---