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M. smegmatis MC2 155 MSMEG_3765 (-)

annotation: transcriptional regulator
coordinates: 3829921 - 3830556
length: 211

LTATSDTGRARKRPGRPPGASDTRDRILASARELFARNGFDKTSIRAVAAGADVDPALVHHYFGTKTQLF
AAAIHIPIDPLEVIGPLREVPVEQIGHTLPRLLLPLWDSELGKGFIATLRSILAGNDVSLVRSFLQEVIV
GEVGSRVDNPAGSGRIRVQYVASQLVGVVMARYILELEPFKSLPVEQIAETIGPNLQRYLTGELPGFGAL
D
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3765--100% (211)transcriptional regulator
M. smegmatis MC2 155MSMEG_5282-4e-2837.02% (208) transcriptional regulator
M. smegmatis MC2 155MSMEG_2182-4e-2635.03% (197) transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1711c-1e-8373.98% (196) hypothetical protein Mb1711c
M. gilvum PYR-GCKMflv_0253-3e-2433.01% (206) TetR family transcriptional regulator
M. tuberculosis H37RvRv1685c-1e-8373.98% (196) hypothetical protein Rv1685c
M. leprae Br4923MLBr_02568-8e-0636.00% (50) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_2351c-6e-6457.73% (194) TetR family transcriptional regulator
M. marinum MMMAR_3548-1e-7369.23% (195) hypothetical protein MMAR_3548
M. avium 104MAV_3088-2e-8275.38% (199) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_3542-3e-2332.61% (184) PUTATIVE transcriptional regulator, TetR family
M. ulcerans Agy99MUL_2781-7e-7268.21% (195) hypothetical protein MUL_2781
M. vanbaalenii PYR-1Mvan_3298-8e-9280.60% (201) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0253|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3542|M.thermoresistible__bu      --------------------------------------------------
Mb1711c|M.bovis_AF2122/97           --------------------------------------------------
Rv1685c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3548|M.marinum_M               MIDKAPFRGARTVLHSTTTASMQPTTTHPAQARRLRSSGELLGARDVSAH
MUL_2781|M.ulcerans_Agy99           ---------------------MQPTTTHPAQARRLRSSGKLLGARDVSAH
MSMEG_3765|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3298|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_3088|M.avium_104                --------------------------------------------------
MAB_2351c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_02568|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0253|M.gilvum_PYR-GCK          ------------MPPPAQTGRRRGRRKG-DPVSRETVLAAAKGRFARDGF
TH_3542|M.thermoresistible__bu      ------------------------------------VLAAAKRRFAQDGY
Mb1711c|M.bovis_AF2122/97           ------------MAAPDNSRRRPGRPAG-SSDTRERILSSARELFAHNGI
Rv1685c|M.tuberculosis_H37Rv        ------------MAAPDNSRRRPGRPAG-SSDTRERILSSARELFAHNGI
MMAR_3548|M.marinum_M               NKPRNVDNTRGGNAPANERRRRPGRPRGNSSDTRQRILASARELFASNGI
MUL_2781|M.ulcerans_Agy99           NKPRNVDNTRGGNAPANERRRRPGRLRGNSSDTRQRILASARELFASNGI
MSMEG_3765|M.smegmatis_MC2_155      ---------MTATSDTGRARKRPGRPPG-ASDTRDRILASARELFARNGF
Mvan_3298|M.vanbaalenii_PYR-1       ---------MTTNAD----RKRPGRPPG-TSDTRDRILECARELFARNGI
MAV_3088|M.avium_104                ---------MTTTGTT---RRRRGRPAG-SSGSRERILASARELFARNGI
MAB_2351c|M.abscessus_ATCC_199      ---------MS--------SKRPGRRPG-TSSARDDILASARKLFSLNGI
MLBr_02568|M.leprae_Br4923          --------------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGY
                                                                        :* .*   *: :* 

Mflv_0253|M.gilvum_PYR-GCK          EKTTLRAIAEDAGVDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGG
TH_3542|M.thermoresistible__bu      EKTTLRAIARDAHVDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGD
Mb1711c|M.bovis_AF2122/97           DRTSIRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREA
Rv1685c|M.tuberculosis_H37Rv        DRTSIRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREA
MMAR_3548|M.marinum_M               DRTSIRAVAAAADVDAALVHHYFGTKQQLFAAAIHLPIDPKLVLKRMQNT
MUL_2781|M.ulcerans_Agy99           DRTSIRAVAAAADVDAALVHHYFGTKQQLFAAAIHLPIDPKLVLKRMQNT
MSMEG_3765|M.smegmatis_MC2_155      DKTSIRAVAAGADVDPALVHHYFGTKTQLFAAAIHIPIDPLEVIGPLREV
Mvan_3298|M.vanbaalenii_PYR-1       TNTSIRSIAAGAGVDPALVHHYFGTKTQLFAAAIEIPIDPMSIIGPLKEV
MAV_3088|M.avium_104                RNTSIRAVAAAAGVDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREV
MAB_2351c|M.abscessus_ATCC_199      DKTSIRAIASDAGVDPALVHHYFGTKLDLFREVVQLPVDPSVVLQPLRDV
MLBr_02568|M.leprae_Br4923          HKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADID
                                     .*:: ::*  * :. .::   :*:*  **   :.  :.    :      

Mflv_0253|M.gilvum_PYR-GCK          -EADIGTRMVRAYLGVWESPESAESMRTMLASATSNPDAREAFRGFIQDY
TH_3542|M.thermoresistible__bu      -DGDVGTRMVRVYLQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREY
Mb1711c|M.bovis_AF2122/97           PVEELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEV
Rv1685c|M.tuberculosis_H37Rv        PVEELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEV
MMAR_3548|M.marinum_M               PTAELGFALPSMLLPMWDS-ELGTGLIASLRSLFGG-GDVDLARSFLQEV
MUL_2781|M.ulcerans_Agy99           PTAELGFALPSMLLPMWDS-ELGTGLIASLRSLFGG-GDVDLARSFLQEV
MSMEG_3765|M.smegmatis_MC2_155      PVEQIGHTLPRLLLPLWDS-ELGKGFIATLRSILAG-NDVSLVRSFLQEV
Mvan_3298|M.vanbaalenii_PYR-1       PVDQLGRALPSLLLPLWDS-ELGKGFIATLRSILAG-SDVSMVRSFLQDL
MAV_3088|M.avium_104                PVDDLGYALPSMLLPLWDS-EVGAAFIATLRSILAG-EEISLFRTFIQDV
MAB_2351c|M.abscessus_ATCC_199      PVDELGVTIPRLIIALWDS-ELGANMLAVFRSALTG-ADDGLVRVFFREV
MLBr_02568|M.leprae_Br4923          FTQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQ
                                       .    :    : .    :        :     .           .: 

Mflv_0253|M.gilvum_PYR-GCK          VLAAVVGTLGG-DDRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDV
TH_3542|M.thermoresistible__bu      LLTAVSGVLGG-GEQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEV
Mb1711c|M.bovis_AF2122/97           VTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQI
Rv1685c|M.tuberculosis_H37Rv        VTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQI
MMAR_3548|M.marinum_M               VTAEMASLVDNPAGTGMIRAQLVASQLLGVVMARYILQIEPFASMPAEDI
MUL_2781|M.ulcerans_Agy99           VTAEMASLVDNPAGTGMIRAQLVASQLLGVVMARYILQIGPFASMPAEDI
MSMEG_3765|M.smegmatis_MC2_155      IVGEVGSRVDNPAGSGRIRVQYVASQLVGVVMARYILELEPFKSLPVEQI
Mvan_3298|M.vanbaalenii_PYR-1       IATEVGGRVDDPPGSGRVRVQFVASQLVGIVMARYILELEPFKSLPVEQI
MAV_3088|M.avium_104                IGVEVGPRVDNPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQI
MAB_2351c|M.abscessus_ATCC_199      LVNIIAERVDSPPGSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQI
MLBr_02568|M.leprae_Br4923          ITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEA
                                    :   :   :      .                 . :    .  .:. :: 

Mflv_0253|M.gilvum_PYR-GCK          IRLVAPTVTRYLTAPADELGLPG------
TH_3542|M.thermoresistible__bu      VRMLAPTVNRYLTADADELGLPSSLTAGS
Mb1711c|M.bovis_AF2122/97           VQTIAPNLQRYLTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv        VQTIAPNLQRYLTGELPDDLAP-------
MMAR_3548|M.marinum_M               ARAIAPNLQRYLTGEI-------------
MUL_2781|M.ulcerans_Agy99           ARAIAPNLQRYLTGEI-------------
MSMEG_3765|M.smegmatis_MC2_155      AETIGPNLQRYLTGELPGFGALD------
Mvan_3298|M.vanbaalenii_PYR-1       VDTVAPNLQRYLTGELPQFSGD-------
MAV_3088|M.avium_104                AATIAPNLQRYLTGDLPDGLAP-------
MAB_2351c|M.abscessus_ATCC_199      ALTVGPNIQRYLTGALPSITP--------
MLBr_02568|M.leprae_Br4923          AELMINLFWHGLKGAPADRDFGPSIVAG-
                                       :   . : *..