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VTTTGTTRRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAAAAGVDSALVHHYFGTKEKLFAAA VQIPIDPMQVIGPLREVPVDDLGYALPSMLLPLWDSEVGAAFIATLRSILAGEEISLFRTFIQDVIGVEV GPRVDNPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQRYLTGDLPDGLAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3088 | - | - | 100% (207) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4902 | - | 5e-09 | 30.15% (136) | hypothetical protein MAV_4902 |
| M. avium 104 | MAV_1243 | - | 3e-08 | 43.75% (64) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 1e-83 | 71.01% (207) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 2e-26 | 36.87% (198) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 1e-83 | 71.01% (207) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_00717 | - | 4e-06 | 38.03% (71) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2351c | - | 1e-58 | 54.64% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2484 | - | 2e-73 | 63.59% (206) | hypothetical protein MMAR_2484 |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 3e-82 | 75.38% (199) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 9e-21 | 30.73% (179) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1664 | - | 2e-68 | 62.44% (197) | hypothetical protein MUL_1664 |
| M. vanbaalenii PYR-1 | Mvan_3298 | - | 5e-83 | 73.50% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0253|M.gilvum_PYR-GCK MPPPAQT---GRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTTLRAIAE
TH_3542|M.thermoresistible__bu --------------------------VLAAAKRRFAQDGYEKTTLRAIAR
Mb1711c|M.bovis_AF2122/97 MAAPDNS---RRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAA
Rv1685c|M.tuberculosis_H37Rv MAAPDNS---RRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAA
MMAR_2484|M.marinum_M METTNTG---RRRPGRPTGTSNTREHILTCARELFALNGLDRTSVRSVAA
MUL_1664|M.ulcerans_Agy99 METTNTG---RRRPGRPTGTSNTREHILTCARELFALNGLDRTSVRSVAA
MSMEG_3765|M.smegmatis_MC2_155 MTATSDTGRARKRPGRPPGASDTRDRILASARELFARNGFDKTSIRAVAA
Mvan_3298|M.vanbaalenii_PYR-1 MTTNAD----RKRPGRPPGTSDTRDRILECARELFARNGITNTSIRSIAA
MAV_3088|M.avium_104 MTTTGTT---RRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAA
MAB_2351c|M.abscessus_ATCC_199 MS--------SKRPGRRPGTSSARDDILASARKLFSLNGIDKTSIRAIAS
MLBr_00717|M.leprae_Br4923 ----------MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAE
:* . *. .. : :*
Mflv_0253|M.gilvum_PYR-GCK DAGVDASMVLYLFGSKEALFRESLRLILD---------PGVLIEALSGG-
TH_3542|M.thermoresistible__bu DAHVDASMVLYLFGSKAELFRESLELILD---------PEMLVAAMTGD-
Mb1711c|M.bovis_AF2122/97 KAGVDAALVHHYFGTKQQLFAAAIHIPID---------PMVIIGPIREAP
Rv1685c|M.tuberculosis_H37Rv KAGVDAALVHHYFGTKQQLFAAAIHIPID---------PMVIIGPIREAP
MMAR_2484|M.marinum_M AAGVDASLVHHYYGTKQQLFAAAIQIPID---------PTVVLEQIVETP
MUL_1664|M.ulcerans_Agy99 AAGVDASLVHHYYGTKQQLFAAAIQIPID---------PTVVLEQIVETP
MSMEG_3765|M.smegmatis_MC2_155 GADVDPALVHHYFGTKTQLFAAAIHIPID---------PLEVIGPLREVP
Mvan_3298|M.vanbaalenii_PYR-1 GAGVDPALVHHYFGTKTQLFAAAIEIPID---------PMSIIGPLKEVP
MAV_3088|M.avium_104 AAGVDSALVHHYFGTKEKLFAAAVQIPID---------PMQVIGPLREVP
MAB_2351c|M.abscessus_ATCC_199 DAGVDPALVHHYFGTKLDLFREVVQLPVD---------PSVVLQPLRDVP
MLBr_00717|M.leprae_Br4923 RAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVR
* *. ::: : : * :* :. * * : :
Mflv_0253|M.gilvum_PYR-GCK EADIGTRMVRAYLG--VWESPESAESMRTMLASATSNPDAR--EAFRGFI
TH_3542|M.thermoresistible__bu DGDVGTRMVRVYLQ--IWESPDTGPTIRAMLQSATSNTDAR--EAFRSFL
Mb1711c|M.bovis_AF2122/97 VEELGYKLPSLLLP--IWDS-ELGAGLIATLRSLISGSDV---GLARSFL
Rv1685c|M.tuberculosis_H37Rv VEELGYKLPSLLLP--IWDS-ELGAGLIATLRSLISGSDV---GLARSFL
MMAR_2484|M.marinum_M VDELGLKLPSVLLP--LWDS-ELGTGLVSTLRALMAGTES---NLARSFL
MUL_1664|M.ulcerans_Agy99 VDELGLKIPSVPLP--LWDS-ELSTGLVATLRALMAGTES---NLARSFL
MSMEG_3765|M.smegmatis_MC2_155 VEQIGHTLPRLLLP--LWDS-ELGKGFIATLRSILAGNDV---SLVRSFL
Mvan_3298|M.vanbaalenii_PYR-1 VDQLGRALPSLLLP--LWDS-ELGKGFIATLRSILAGSDV---SMVRSFL
MAV_3088|M.avium_104 VDDLGYALPSMLLP--LWDS-EVGAAFIATLRSILAGEEI---SLFRTFI
MAB_2351c|M.abscessus_ATCC_199 VDELGVTIPRLIIA--LWDS-ELGANMLAVFRSALTGADD---GLVRVFF
MLBr_00717|M.leprae_Br4923 VGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRI
:. * : . : . . :
Mflv_0253|M.gilvum_PYR-GCK QDYVLAAVVGTLGG-DDRARLRAMLAASSLVGTAMMRYLMEIPPLSELAT
TH_3542|M.thermoresistible__bu REYLLTAVSGVLGG-GEQARLRAELAATGLVGTAMLRYIMRVPPLAELST
Mb1711c|M.bovis_AF2122/97 EEVVTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPA
Rv1685c|M.tuberculosis_H37Rv EEVVTVELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPA
MMAR_2484|M.marinum_M QEVVTSEVGSRVDSPTGTGRIRAQFVASQLLGVVMARHIVKIEPFASLPA
MUL_1664|M.ulcerans_Agy99 QEVVTSEVGSRVDSPTGTGRIRAQFVTSQLLGVVMARHIVKIEPFASLPA
MSMEG_3765|M.smegmatis_MC2_155 QEVIVGEVGSRVDNPAGSGRIRVQYVASQLVGVVMARYILELEPFKSLPV
Mvan_3298|M.vanbaalenii_PYR-1 QDLIATEVGGRVDDPPGSGRVRVQFVASQLVGIVMARYILELEPFKSLPV
MAV_3088|M.avium_104 QDVIGVEVGPRVDNPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPP
MAB_2351c|M.abscessus_ATCC_199 REVLVNIIAERVDSPPGSGVLRAEFAITQMAGILVGRYIMAIEPLASLTA
MLBr_00717|M.leprae_Br4923 GDVVSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLA
: : : : : :: . .
Mflv_0253|M.gilvum_PYR-GCK EDVIRLVAPTVTRY--LTAPADELGLPG------
TH_3542|M.thermoresistible__bu EEVVRMLAPTVNRY--LTADADELGLPSSLTAGS
Mb1711c|M.bovis_AF2122/97 EQIVQTIAPNLQRY--LTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv EQIVQTIAPNLQRY--LTGELPDDLAP-------
MMAR_2484|M.marinum_M DQVAQAIAPTLQRY--LTGELPEEIAS-------
MUL_1664|M.ulcerans_Agy99 DQVAQAIAPTLQRY--LNR---------------
MSMEG_3765|M.smegmatis_MC2_155 EQIAETIGPNLQRY--LTGELPGFGALD------
Mvan_3298|M.vanbaalenii_PYR-1 EQIVDTVAPNLQRY--LTGELPQFSGD-------
MAV_3088|M.avium_104 EQIAATIAPNLQRY--LTGDLPDGLAP-------
MAB_2351c|M.abscessus_ATCC_199 EQIALTVGPNIQRY--LTGALPSITP--------
MLBr_00717|M.leprae_Br4923 DSCAHALLDAIARVPEISKELADAMAIARQPPQ-
:. : : * :.