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ISHSCRPGRLHDVKVRPFEEVVAHHGATVLRVCRAVVGAADAEDAWSETFLSALRGYPDLPEDANVEAWL VTIAHRRALDVGRARARRAVPVEAVPERADARADPAARDPDLWTALQRLPAKQRHAVAYHHIAGLPFTEI AAILGNSPDAARRAAADGIKNLRAHYREDEKP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2496 | - | - | 100% (173) | ECF subfamily RNA polymerase sigma-24 factor |
| M. vanbaalenii PYR-1 | Mvan_4710 | - | 4e-10 | 34.84% (155) | ECF subfamily RNA polymerase sigma-24 factor |
| M. vanbaalenii PYR-1 | Mvan_5003 | - | 4e-09 | 31.06% (132) | ECF subfamily RNA polymerase sigma-24 factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3448c | sigD | 4e-10 | 33.78% (148) | RNA polymerase sigma factor SigD |
| M. gilvum PYR-GCK | Mflv_3908 | - | 2e-82 | 85.96% (171) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3414c | sigD | 4e-10 | 33.78% (148) | RNA polymerase sigma factor SigD |
| M. leprae Br4923 | MLBr_01448 | - | 6e-08 | 27.61% (134) | RNA polymerase sigma factor SigC |
| M. abscessus ATCC 19977 | MAB_1248 | - | 3e-14 | 35.21% (142) | RNA polymerase sigma factor |
| M. marinum M | MMAR_1196 | sigJ | 1e-09 | 34.15% (164) | alternative RNA polymerase sigma factor SigJ |
| M. avium 104 | MAV_2475 | - | 1e-13 | 37.23% (137) | RNA polymerase sigma factor |
| M. smegmatis MC2 155 | MSMEG_4315 | - | 2e-48 | 60.00% (150) | RNA polymerase sigma factor, sigma-70 family protein |
| M. thermoresistible (build 8) | TH_1681 | sigD | 9e-10 | 31.54% (149) | PROBABLE ALTERNATIVE RNA POLYMERASE SIGMA-D FACTOR SIGD |
| M. ulcerans Agy99 | MUL_0897 | sigD | 9e-10 | 33.78% (148) | RNA polymerase sigma factor SigD |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2496|M.vanbaalenii_PYR-1 -------------------------MISHSCRPGRLHDVKVRPFEEVVAH
Mflv_3908|M.gilvum_PYR-GCK -------------------------MISHPGVPRRLHDVKVRPFEEIVAC
MSMEG_4315|M.smegmatis_MC2_155 ---------------------------------------MKAPFERVVQR
Mb3448c|M.bovis_AF2122/97 MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLET
Rv3414c|M.tuberculosis_H37Rv MVDPGVSPGCVRFVTLEISPSMTMQGERLDAVVAEAVAGDRNALREVLET
MUL_0897|M.ulcerans_Agy99 ---------------MEISPSMTIEGERLDAVVAEAVAGDRNALREVLET
TH_1681|M.thermoresistible__bu ------------------------------------VAGDRDALRHVLET
MAB_1248|M.abscessus_ATCC_1997 -----------------MVLPLLPRGELLASLSDEMLA--RRAQQGDSEA
MLBr_01448|M.leprae_Br4923 -------------------MIASSGDEAVTDLALAAARGSKRALEAFIKA
MMAR_1196|M.marinum_M ------------------------------------MAVLGAQAASTFES
MAV_2475|M.avium_104 ----------------------------------MNAPRNLAELAQRFDD
Mvan_2496|M.vanbaalenii_PYR-1 HGATVLRVCRAVVGA--------ADAEDAWSETFLSALRGYPDLPEDA-N
Mflv_3908|M.gilvum_PYR-GCK HGATVLRVCRAVVGP--------VDAEDAWSETFLSALRAYPELPEDA-N
MSMEG_4315|M.smegmatis_MC2_155 HGPAVLRVCTFVLGP--------LDAEDAWSDTFLAALRAYPDLADDA-N
Mb3448c|M.bovis_AF2122/97 IRPIVVRYCRARVGTVERSG---LSADDVAQEVCLATITALPRYRDRGRP
Rv3414c|M.tuberculosis_H37Rv IRPIVVRYCRARVGTVERSG---LSADDVAQEVCLATITALPRYRDRGRP
MUL_0897|M.ulcerans_Agy99 IRPIVVRYCRARVGTVERSG---LSADDVAQEVCLATITALPRYRDRGRP
TH_1681|M.thermoresistible__bu IRPLVLRYCRARVGAGERSG---LSADDVAQEVCLAAITALPRYKDQGRP
MAB_1248|M.abscessus_ATCC_1997 FDVLVVRHGPALLRFVARTYPERAEYDDIVQETFIAAWKGLPSFAFRS-Q
MLBr_01448|M.leprae_Br4923 TQQDVWRFVAYLSDVG--------NADDLTQETFLRAIGAIERFSGHS-S
MMAR_1196|M.marinum_M LRPHLMSVAYRLTGT-------VADAEDIVQEAWLR-WDAAPGR-DDVAD
MAV_2475|M.avium_104 DRRHLRSVAFQLLGS-------LADADDAVQSAWLKASRADFAAVDNL--
: . :* ... : .
Mvan_2496|M.vanbaalenii_PYR-1 VEAWLVTIAHRRALDVGRARARR-------AVPVEAVPERADARADP---
Mflv_3908|M.gilvum_PYR-GCK VEAWLVTIAHRRALDLGRARSRR-------AVPTDSVPERCDARADP---
MSMEG_4315|M.smegmatis_MC2_155 VEAWLVTIAHRKCVDIIRRRERE-------ALAIGDVPDRPTTIGVP---
Mb3448c|M.bovis_AF2122/97 FLAFLYGIAAHKVADAHRAAGRDR------AYPAETLPERWSADAGPEQM
Rv3414c|M.tuberculosis_H37Rv FLAFLYGIAAHKVADAHRAAGRDR------AYPAETLPERWSADAGPEQM
MUL_0897|M.ulcerans_Agy99 FLAFLYGIAAHKVADAHRAAGRDL------AYPAESVPERRSADAGPEQL
TH_1681|M.thermoresistible__bu FLAFVYGIAAHKVADAHRAAARNR------AEPTDVLPERISTENGPEQM
MAB_1248|M.abscessus_ATCC_1997 FRTWLYSLASRKTVDAMRRRRRD--------FDIDEVPEVADAGAGPSER
MLBr_01448|M.leprae_Br4923 GRTWLLAIARRVVADHIRRAQTRP------RTTFDGYPERMLNADRHARG
MMAR_1196|M.marinum_M LRAWLTTVVSRLGLDKLRSAARRRETYTGHWLPEPVVTGLGDAGGADPLS
MAV_2475|M.avium_104 -SGWFTTITAREALDQLRARKRRAELP---LAAPEELDRLAVAASSPADE
:. :. : * *
Mvan_2496|M.vanbaalenii_PYR-1 ---AARDP--DLWTALQRLPAKQRHAVAYHHIAGLPFTEIAAILGNSPDA
Mflv_3908|M.gilvum_PYR-GCK ---AARDP--DLWAALARLPDKQRHAVAYHHIAGLPFTEIAVILGNSPEA
MSMEG_4315|M.smegmatis_MC2_155 ---GAADD--QLTSAVRALPPKQRQAVAYHYFVGLPYAEIAALLGGTADA
Mb3448c|M.bovis_AF2122/97 AIEADSVT--RMNELLEILPAKQREILILRVVVGLSAEETAAAVGSTTGA
Rv3414c|M.tuberculosis_H37Rv AIEADSVT--RMNELLEILPAKQREILILRVVVGLSAEETAAAVGSTTGA
MUL_0897|M.ulcerans_Agy99 AIEADSVT--RMNELLEILPAKQREILILRVVVGLSAEETAAAVGSTTGA
TH_1681|M.thermoresistible__bu AIDAESSA--RMQKLLQVLPEKQREILILRVVVGMSAEETAEAVGSTAGA
MAB_1248|M.abscessus_ATCC_1997 ALDGDFLA--ALSRELSQLPYAARAAWWLREVYDLPLAEIATVLRTTEGS
MLBr_01448|M.leprae_Br4923 ---FEDLV--EVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVGT
MMAR_1196|M.marinum_M AVVAAEDARFAVMVVLERLSPDQRVAFVLHDGFAMPFAEVAGVIGASEAA
MAV_2475|M.avium_104 DTLLAESVSTALLVVLDRLSPAQRVAFVLHDVFAMPFETIAELLNRSPDA
: : *. * :. * . :
Mvan_2496|M.vanbaalenii_PYR-1 ARRAAADGIKNLRAHYREDEKP----------------------------
Mflv_3908|M.gilvum_PYR-GCK ARRAAADGIKALRSYYREDESA----------------------------
MSMEG_4315|M.smegmatis_MC2_155 ARKAASDGIATLRTHYPDALPKGAH------R------------------
Mb3448c|M.bovis_AF2122/97 VRVAQHRALQRLKDEIVAAGDYA---------------------------
Rv3414c|M.tuberculosis_H37Rv VRVAQHRALQRLKDEIVAAGDYA---------------------------
MUL_0897|M.ulcerans_Agy99 VRVAQHRALQRLKDEIVAAGDYA---------------------------
TH_1681|M.thermoresistible__bu VRVAQHRALARLKAEVMATGHHHG--------------------------
MAB_1248|M.abscessus_ATCC_1997 VRGNLQRTRKRLAETLKDFRP-----------------------------
MLBr_01448|M.leprae_Br4923 IRSRVARARDALLADTEHNHLTG---------------------------
MMAR_1196|M.marinum_M ARQLASRARKAVAAAPPPQPDPTHN------EVVGRLMAAMASGDLHSVV
MAV_2475|M.avium_104 AKKLASRARARLHAAPAGPPRRDGHRIERHVEVVQAFLAASRGGDIAALL
: :
Mvan_2496|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3908|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 --------------------------------------------------
Mb3448c|M.bovis_AF2122/97 --------------------------------------------------
Rv3414c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0897|M.ulcerans_Agy99 --------------------------------------------------
TH_1681|M.thermoresistible__bu --------------------------------------------------
MAB_1248|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MMAR_1196|M.marinum_M SLLHPDVTFTGDANGRAPTAARVICGADKVARFMLGLA--RRYGPAFYTA
MAV_2475|M.avium_104 QLLAADVLRTVDPVLVPADVPTALRGATRVAQETRRFAGRARAGAVMLID
Mvan_2496|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3908|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 --------------------------------------------------
Mb3448c|M.bovis_AF2122/97 --------------------------------------------------
Rv3414c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0897|M.ulcerans_Agy99 --------------------------------------------------
TH_1681|M.thermoresistible__bu --------------------------------------------------
MAB_1248|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MMAR_1196|M.marinum_M NQLALVNGELGSYTLGTAGDGGHWAMLPRITAMTVRDGKVCALWDIANPD
MAV_2475|M.avium_104 GTPGIVIAARGRAQILLMIGIGADDRIHTIDITGDPERIRRAALALPPAV
Mvan_2496|M.vanbaalenii_PYR-1 ------------
Mflv_3908|M.gilvum_PYR-GCK ------------
MSMEG_4315|M.smegmatis_MC2_155 ------------
Mb3448c|M.bovis_AF2122/97 ------------
Rv3414c|M.tuberculosis_H37Rv ------------
MUL_0897|M.ulcerans_Agy99 ------------
TH_1681|M.thermoresistible__bu ------------
MAB_1248|M.abscessus_ATCC_1997 ------------
MLBr_01448|M.leprae_Br4923 ------------
MMAR_1196|M.marinum_M KFSGSPLRDLVG
MAV_2475|M.avium_104 RFRNITT-----