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MKAPFERVVQRHGPAVLRVCTFVLGPLDAEDAWSDTFLAALRAYPDLADDANVEAWLVTIAHRKCVDIIR RREREALAIGDVPDRPTTIGVPGAADDQLTSAVRALPPKQRQAVAYHYFVGLPYAEIAALLGGTADAARK AASDGIATLRTHYPDALPKGAHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4315 | - | - | 100% (163) | RNA polymerase sigma factor, sigma-70 family protein |
| M. smegmatis MC2 155 | MSMEG_0573 | - | 2e-08 | 28.21% (156) | putative ECF sigma factor RpoE1 |
| M. smegmatis MC2 155 | MSMEG_5072 | - | 9e-08 | 29.30% (157) | RNA polymerase sigma factor SigE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1253 | sigE | 2e-08 | 29.30% (157) | RNA polymerase sigma factor SigE |
| M. gilvum PYR-GCK | Mflv_3908 | - | 5e-47 | 58.00% (150) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv1221 | sigE | 2e-08 | 29.30% (157) | RNA polymerase sigma factor SigE |
| M. leprae Br4923 | MLBr_01076 | sigE | 4e-09 | 29.88% (164) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_4733 | - | 3e-12 | 34.42% (154) | putative RNA polymerase sigma factor |
| M. marinum M | MMAR_0265 | sigC_1 | 6e-09 | 30.20% (149) | ECF subfamily RNA polymerase sigma factor |
| M. avium 104 | MAV_2018 | - | 3e-11 | 32.57% (175) | RNA polymerase ECF-subfamily protein sigma factor |
| M. thermoresistible (build 8) | TH_2414 | sigM | 2e-10 | 31.71% (164) | POSSIBLE ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGM |
| M. ulcerans Agy99 | MUL_4849 | sigC_1 | 4e-09 | 30.20% (149) | ECF subfamily RNA polymerase sigma factor |
| M. vanbaalenii PYR-1 | Mvan_2496 | - | 2e-48 | 60.00% (150) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3908|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 --------------------------------------------------
Mb1253|M.bovis_AF2122/97 ------MELLGGPRVGNTESQLCVADGDDLPTYCS-ANSEDLNITTITTL
Rv1221|M.tuberculosis_H37Rv ------MELLGGPRVGNTESQLCVADGDDLPTYCS-ANSEDLNITTITTL
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGR-WTGNTQCPLRVVPGDESPTLDGRASPEDLIITNL--L
MMAR_0265|M.marinum_M ----------------------MVTGGAD---------------------
MUL_4849|M.ulcerans_Agy99 ----------------------MVTGGAD---------------------
MAB_4733|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2018|M.avium_104 --------------------------------------------------
TH_2414|M.thermoresistible__bu --------------------------------------------------
Mflv_3908|M.gilvum_PYR-GCK ----------------------MISHPGVPRRLHDVKVRPFEEIVACHGA
Mvan_2496|M.vanbaalenii_PYR-1 ----------------------MISHSCRPGRLHDVKVRPFEEVVAHHGA
MSMEG_4315|M.smegmatis_MC2_155 ------------------------------------MKAPFERVVQRHGP
Mb1253|M.bovis_AF2122/97 SPTSMSHPQQVRDDQWVEPSDQLQGTAVFDATGDKATMPSWDELVRQHAD
Rv1221|M.tuberculosis_H37Rv SPTSMSHPQQVRDDQWVEPSDQLQGTAVFDATGDKATMPSWDELVRQHAD
MLBr_01076|M.leprae_Br4923 SPTIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAA
MMAR_0265|M.marinum_M --------------------EQITVLAMAAGRGDRAALA---EFIEATQR
MUL_4849|M.ulcerans_Agy99 --------------------EQITVLAMAAGRGDRAALA---EFIEATQR
MAB_4733|M.abscessus_ATCC_1997 --------------------------------------MDLIEKFEAERP
MAV_2018|M.avium_104 --------------------------------MTSPDAADLTARFEAARP
TH_2414|M.thermoresistible__bu -------------VKSFGDDRRSRTDAELLAAHVDGDRYAFEELFHRHHR
.
Mflv_3908|M.gilvum_PYR-GCK TVLRVCRAVV-GPVDAEDAWSETFLSALRAYPELPEDANVEAWLVTIAHR
Mvan_2496|M.vanbaalenii_PYR-1 TVLRVCRAVV-GAADAEDAWSETFLSALRGYPDLPEDANVEAWLVTIAHR
MSMEG_4315|M.smegmatis_MC2_155 AVLRVCTFVL-GPLDAEDAWSDTFLAALRAYPDLADDANVEAWLVTIAHR
Mb1253|M.bovis_AF2122/97 RVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQP-GTFEGWLHRITTN
Rv1221|M.tuberculosis_H37Rv RVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQP-GTFEGWLHRITTN
MLBr_01076|M.leprae_Br4923 RVYWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQP-GTFEGWLHRITTN
MMAR_0265|M.marinum_M DVWRLVAYLS-DPACADDLTQETFLRAIGALPRFAGRSNARTWLFSIARR
MUL_4849|M.ulcerans_Agy99 DVWRLVAYLS-DPACADDLTQETFLRAIGALPRFAGRSNARTWLFSIARR
MAB_4733|M.abscessus_ATCC_1997 RLLSVAHRILGSRHDAEDAVQSAWIRAQSAAP--NRVDNAPGWLTTVTAR
MAV_2018|M.avium_104 RLGALAYRMLGSIDDAQDAVQEAWLRLDRSGG--ADIANLDAWLTTVVAR
TH_2414|M.thermoresistible__bu QLYRLARLTSRHPEDAADALQEAMLSAHRSAPAFRYDSAVSSWLHRIVVN
: : * * ..: : . ** :. .
Mflv_3908|M.gilvum_PYR-GCK RALDLGRARSRRA------VPTDSVPERCDARADPAARD--------PDL
Mvan_2496|M.vanbaalenii_PYR-1 RALDVGRARARRA------VPVEAVPERADARADPAARD--------PDL
MSMEG_4315|M.smegmatis_MC2_155 KCVDIIRRREREA------LAIGDVPDRPTTIGVPGAAD--------DQL
Mb1253|M.bovis_AF2122/97 LFLDMVRRRARIR------MEALPEDYDRVPADEPNPEQIYHDARLGPDL
Rv1221|M.tuberculosis_H37Rv LFLDMVRRRARIR------MEALPEDYDRVPADEPNPEQIYHDARLGPDL
MLBr_01076|M.leprae_Br4923 LFLDMVRRRARIR------MDALPDDYDRVPADEPNPEQIYHDSRLGPDL
MMAR_0265|M.marinum_M VVVDQIRYKTRRP------RPAYVADLGEALG-QARRGSRFEDI---VEI
MUL_4849|M.ulcerans_Agy99 VVVDQIRYKTRRP------RPAYVADLGEALG-QARRGSRFEDI---VEI
MAB_4733|M.abscessus_ATCC_1997 LCLDQLRAR-ERHGEVPLTAEHISD------TQFAADEEFLRREEVSRAV
MAV_2018|M.avium_104 ICLNMLRDRRTRDGAEP--AAHLPDPIVEPAGEFDPEHRAMLADAVGMAL
TH_2414|M.thermoresistible__bu SCLDRLRRNKSRP------TAALRDDVAATGDPTAAVDT-------AIVV
:: * . :
Mflv_3908|M.gilvum_PYR-GCK WAALARLPDKQRHAVAYHHIAGLPFTEIAVILGNSPEAARRAAADGIKAL
Mvan_2496|M.vanbaalenii_PYR-1 WTALQRLPAKQRHAVAYHHIAGLPFTEIAAILGNSPDAARRAAADGIKNL
MSMEG_4315|M.smegmatis_MC2_155 TSAVRALPPKQRQAVAYHYFVGLPYAEIAALLGGTADAARKAASDGIATL
Mb1253|M.bovis_AF2122/97 QAALASLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQAL
Rv1221|M.tuberculosis_H37Rv QAALASLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQAL
MLBr_01076|M.leprae_Br4923 QAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQAL
MMAR_0265|M.marinum_M RLLLDGLDEKRREALIFTQVLGLSYAEAAQICGSPIGTIRSRVARAR---
MUL_4849|M.ulcerans_Agy99 RLLLDGLDEKRREALIFTQVLGLSYAEAAQICGSPIGTIRSRVARAR---
MAB_4733|M.abscessus_ATCC_1997 LVVLDELSPKQRVAYVLHDLFAVPFGDIAAVLDTTAVSAKKLASRARARL
MAV_2018|M.avium_104 FVVLDTLPPAERLAFVLHDVFAVPFAQIAAIVDGTPESARKLASRARRRI
TH_2414|M.thermoresistible__bu QRALMTLPVEQRAAVVAVDMQGYSVAETARLLGVAEGTVKSRCSRARAKL
: * * * . . . : . . : : .
Mflv_3908|M.gilvum_PYR-GCK RSYYREDESA----------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 RAHYREDEKP----------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 RTHYPDALPKGAHR------------------------------------
Mb1253|M.bovis_AF2122/97 RDY-LAAHPEHGEC--AVHVNPVR--------------------------
Rv1221|M.tuberculosis_H37Rv RDY-LAAHPEHGEC--AVHVNPVR--------------------------
MLBr_01076|M.leprae_Br4923 RDYLLTAHPRDGATTDATHVKSA---------------------------
MMAR_0265|M.marinum_M DDLLRAAREGERAG------------------------------------
MUL_4849|M.ulcerans_Agy99 DDLLRAAREGERAG------------------------------------
MAB_4733|M.abscessus_ATCC_1997 GAADPERAREVGSQLEIVEAFLSAARGGDIERLITLMAPDVIRTVDHTLI
MAV_2018|M.avium_104 ERADPVPDGDLAAQREVVDAFFAAGRSGDFDRLVSVLHPDVVLRGDFG--
TH_2414|M.thermoresistible__bu AGVLRHLDSRSPVGARSRQ-------------------------------
Mflv_3908|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 --------------------------------------------------
Mb1253|M.bovis_AF2122/97 --------------------------------------------------
Rv1221|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01076|M.leprae_Br4923 --------------------------------------------------
MMAR_0265|M.marinum_M --------------------------------------------------
MUL_4849|M.ulcerans_Agy99 --------------------------------------------------
MAB_4733|M.abscessus_ATCC_1997 PSGAATLVRGAQAVAEETRSFTDRIAVAAILLIDGRVGAVIAPGGHPFAL
MAV_2018|M.avium_104 PATATVRVQGAAAVAKLARSYAGPEREACAATVNGAAGAVIFVAGRAASV
TH_2414|M.thermoresistible__bu --------------------------------------------------
Mflv_3908|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 --------------------------------------------------
Mb1253|M.bovis_AF2122/97 --------------------------------------------------
Rv1221|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01076|M.leprae_Br4923 --------------------------------------------------
MMAR_0265|M.marinum_M --------------------------------------------------
MUL_4849|M.ulcerans_Agy99 --------------------------------------------------
MAB_4733|M.abscessus_ATCC_1997 IRMDTDGRLVTCIDIAPYTSGDAALSLIATAGSKVSYSPGESGRRIDPRG
MAV_2018|M.avium_104 MGFVVRGGRIRAIDVLADPD------------------------RIAKLE
TH_2414|M.thermoresistible__bu --------------------------------------------------
Mflv_3908|M.gilvum_PYR-GCK --------
Mvan_2496|M.vanbaalenii_PYR-1 --------
MSMEG_4315|M.smegmatis_MC2_155 --------
Mb1253|M.bovis_AF2122/97 --------
Rv1221|M.tuberculosis_H37Rv --------
MLBr_01076|M.leprae_Br4923 --------
MMAR_0265|M.marinum_M --------
MUL_4849|M.ulcerans_Agy99 --------
MAB_4733|M.abscessus_ATCC_1997 SGLPRVDH
MAV_2018|M.avium_104 LGALRADH
TH_2414|M.thermoresistible__bu --------