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VISHPGVPRRLHDVKVRPFEEIVACHGATVLRVCRAVVGPVDAEDAWSETFLSALRAYPELPEDANVEAW LVTIAHRRALDLGRARSRRAVPTDSVPERCDARADPAARDPDLWAALARLPDKQRHAVAYHHIAGLPFTE IAVILGNSPEAARRAAADGIKALRSYYREDESA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3908 | - | - | 100% (173) | ECF subfamily RNA polymerase sigma-24 factor |
| M. gilvum PYR-GCK | Mflv_4912 | - | 4e-09 | 32.21% (149) | RNA polymerase sigma factor SigD |
| M. gilvum PYR-GCK | Mflv_5063 | - | 8e-08 | 32.62% (141) | ECF subfamily RNA polymerase sigma-24 factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1253 | sigE | 8e-11 | 33.96% (159) | RNA polymerase sigma factor SigE |
| M. tuberculosis H37Rv | Rv1221 | sigE | 8e-11 | 33.96% (159) | RNA polymerase sigma factor SigE |
| M. leprae Br4923 | MLBr_01076 | sigE | 2e-10 | 33.33% (159) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_1248 | - | 6e-13 | 32.70% (159) | RNA polymerase sigma factor |
| M. marinum M | MMAR_4216 | sigE | 3e-10 | 33.33% (159) | alternative RNA polymerase sigma factor SigE |
| M. avium 104 | MAV_2475 | - | 6e-12 | 35.94% (128) | RNA polymerase sigma factor |
| M. smegmatis MC2 155 | MSMEG_4315 | - | 6e-47 | 58.00% (150) | RNA polymerase sigma factor, sigma-70 family protein |
| M. thermoresistible (build 8) | TH_0545 | sigE | 7e-10 | 33.33% (159) | ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGE |
| M. ulcerans Agy99 | MUL_4519 | sigE | 2e-10 | 33.33% (159) | RNA polymerase sigma factor SigE |
| M. vanbaalenii PYR-1 | Mvan_2496 | - | 2e-82 | 85.96% (171) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1253|M.bovis_AF2122/97 ------MELLGGPRVGNTESQLCVADGDDLPTYCSANSEDLNITTIT-TL
Rv1221|M.tuberculosis_H37Rv ------MELLGGPRVGNTESQLCVADGDDLPTYCSANSEDLNITTIT-TL
MMAR_4216|M.marinum_M ------MER-GGRGLGNTEWQLRVAAGDELP--MSDGREKPEEHTIT-TL
MUL_4519|M.ulcerans_Agy99 ------MER-GGRGLGNTAWQLRVAAGDELP--MSDGREKPEEHTIT-TL
TH_0545|M.thermoresistible__bu ------------------------------------------------MS
MLBr_01076|M.leprae_Br4923 MGDGIGMER-EGRWTGNTQCPLRVVPGDESP--TLDGRASPEDLIITNLL
Mflv_3908|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1248|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2475|M.avium_104 --------------------------------------------------
Mb1253|M.bovis_AF2122/97 SPTSMSHPQQVRDDQWVEPSDQLQGTAVFDATGDKATMPSWDELVRQHAD
Rv1221|M.tuberculosis_H37Rv SPTSMSHPQQVRDDQWVEPSDQLQGTAVFDATGDKATMPSWDELVRQHAD
MMAR_4216|M.marinum_M STTTMSHPQLVRDDEWAETSDGLLGTAVFDATGDKAAMPSWDELVRQHAD
MUL_4519|M.ulcerans_Agy99 STTTMSHPQLVRDDEWAETSDGLLGTAVFDATGDKAAMPSWDELVRQHAD
TH_0545|M.thermoresistible__bu VPASMTHFAPPQATEWAEPVEEPTGTAVFDATGDKSTMPSWDELVRQHAD
MLBr_01076|M.leprae_Br4923 SPTIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAA
Mflv_3908|M.gilvum_PYR-GCK ----------------------MISHPGVPRRLHDVKVRPFEEIVACHGA
Mvan_2496|M.vanbaalenii_PYR-1 ----------------------MISHSCRPGRLHDVKVRPFEEVVAHHGA
MSMEG_4315|M.smegmatis_MC2_155 ------------------------------------MKAPFERVVQRHGP
MAB_1248|M.abscessus_ATCC_1997 ----MVLPLLPRGE-----LLASLSDEMLARRAQQGDSEAFDVLVVRHGP
MAV_2475|M.avium_104 -------------------------------MNAPRNLAELAQRFDDDRR
. .
Mb1253|M.bovis_AF2122/97 RVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTN
Rv1221|M.tuberculosis_H37Rv RVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTN
MMAR_4216|M.marinum_M RVYRLAYRLSGNQQDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTN
MUL_4519|M.ulcerans_Agy99 RVYRLAYRLSGNQQDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTN
TH_0545|M.thermoresistible__bu RVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPGT-FEGWLHRITTN
MLBr_01076|M.leprae_Br4923 RVYWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTN
Mflv_3908|M.gilvum_PYR-GCK TVLRVCRAVVG-PVDAEDAWSETFLSALRAYPELPEDANVEAWLVTIAHR
Mvan_2496|M.vanbaalenii_PYR-1 TVLRVCRAVVG-AADAEDAWSETFLSALRGYPDLPEDANVEAWLVTIAHR
MSMEG_4315|M.smegmatis_MC2_155 AVLRVCTFVLG-PLDAEDAWSDTFLAALRAYPDLADDANVEAWLVTIAHR
MAB_1248|M.abscessus_ATCC_1997 ALLRFVARTYPERAEYDDIVQETFIAAWKGLPSFAFRSQFRTWLYSLASR
MAV_2475|M.avium_104 HLRSVAFQLLGSLADADDAVQSAWLKASR--ADFAAVDNLSGWFTTITAR
: . : :* ..::: . : . . *: :: .
Mb1253|M.bovis_AF2122/97 LFLDMVRRRARIRMEALPEDYDR----VPADEPNPEQIYHDARLGPDLQA
Rv1221|M.tuberculosis_H37Rv LFLDMVRRRARIRMEALPEDYDR----VPADEPNPEQIYHDARLGPDLQA
MMAR_4216|M.marinum_M LFLDMVRRRSRIRMEALPEDYDR----VPADDPNPEQIYHDSRLGPDLQA
MUL_4519|M.ulcerans_Agy99 LFLDMVRRRSRIRMEALPEDYDR----VPADDPNPEQIYHDSRLGPDLQA
TH_0545|M.thermoresistible__bu LFLDMVRRRGRIRMESLPEDYDR----VPGNSPNPEQIYHDARLGPDLQA
MLBr_01076|M.leprae_Br4923 LFLDMVRRRARIRMDALPDDYDR----VPADEPNPEQIYHDSRLGPDLQA
Mflv_3908|M.gilvum_PYR-GCK RALDLGRARSRR-----AVPTDS----VPE---RCDARADPAARDPDLWA
Mvan_2496|M.vanbaalenii_PYR-1 RALDVGRARARR-----AVPVEA----VPE---RADARADPAARDPDLWT
MSMEG_4315|M.smegmatis_MC2_155 KCVDIIRRRERE-----ALAIGD----VPD---RPTTIGVPGAADDQLTS
MAB_1248|M.abscessus_ATCC_1997 KTVDAMRRRRRD---FDIDEVPE----VADAGAGPSERALDGDFLAALSR
MAV_2475|M.avium_104 EALDQLRARKRRAELPLAAPEELDRLAVAASSPADEDTLLAESVSTALLV
:* * * * *. *
Mb1253|M.bovis_AF2122/97 ALASLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRD
Rv1221|M.tuberculosis_H37Rv ALASLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRD
MMAR_4216|M.marinum_M ALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRD
MUL_4519|M.ulcerans_Agy99 ALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRD
TH_0545|M.thermoresistible__bu ALDSLPPDFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRD
MLBr_01076|M.leprae_Br4923 ALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRD
Mflv_3908|M.gilvum_PYR-GCK ALARLPDKQRHAVAYHHIAGLPFTEIAVILGNSPEAARRAAADGIKALRS
Mvan_2496|M.vanbaalenii_PYR-1 ALQRLPAKQRHAVAYHHIAGLPFTEIAAILGNSPDAARRAAADGIKNLRA
MSMEG_4315|M.smegmatis_MC2_155 AVRALPPKQRQAVAYHYFVGLPYAEIAALLGGTADAARKAASDGIATLRT
MAB_1248|M.abscessus_ATCC_1997 ELSQLPYAARAAWWLREVYDLPLAEIATVLRTTEGSVRGNLQRTRKRLAE
MAV_2475|M.avium_104 VLDRLSPAQRVAFVLHDVFAMPFETIAELLNRSPDAAKKLASRARARLHA
: *. * * . :. *. * . :.: *
Mb1253|M.bovis_AF2122/97 Y-LAAHPEHGECAVHVN-PVR-----------------------------
Rv1221|M.tuberculosis_H37Rv Y-LAAHPEHGECAVHVN-PVR-----------------------------
MMAR_4216|M.marinum_M Y-LAAHPEHSELSPRLVGTAR-----------------------------
MUL_4519|M.ulcerans_Agy99 Y-LAAHPEHSELSPRLVGTAR-----------------------------
TH_0545|M.thermoresistible__bu Y-LARHSQNSGQSATTS---------------------------------
MLBr_01076|M.leprae_Br4923 YLLTAHPRDGATTDATHVKSA-----------------------------
Mflv_3908|M.gilvum_PYR-GCK YYREDESA------------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 HYREDEKP------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 HYPDALPKGAHR--------------------------------------
MAB_1248|M.abscessus_ATCC_1997 TLKDFRP-------------------------------------------
MAV_2475|M.avium_104 APAGPPRRDGHRIERHVEVVQAFLAASRGGDIAALLQLLAADVLRTVDPV
Mb1253|M.bovis_AF2122/97 --------------------------------------------------
Rv1221|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4216|M.marinum_M --------------------------------------------------
MUL_4519|M.ulcerans_Agy99 --------------------------------------------------
TH_0545|M.thermoresistible__bu --------------------------------------------------
MLBr_01076|M.leprae_Br4923 --------------------------------------------------
Mflv_3908|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1248|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2475|M.avium_104 LVPADVPTALRGATRVAQETRRFAGRARAGAVMLIDGTPGIVIAARGRAQ
Mb1253|M.bovis_AF2122/97 -------------------------------------------
Rv1221|M.tuberculosis_H37Rv -------------------------------------------
MMAR_4216|M.marinum_M -------------------------------------------
MUL_4519|M.ulcerans_Agy99 -------------------------------------------
TH_0545|M.thermoresistible__bu -------------------------------------------
MLBr_01076|M.leprae_Br4923 -------------------------------------------
Mflv_3908|M.gilvum_PYR-GCK -------------------------------------------
Mvan_2496|M.vanbaalenii_PYR-1 -------------------------------------------
MSMEG_4315|M.smegmatis_MC2_155 -------------------------------------------
MAB_1248|M.abscessus_ATCC_1997 -------------------------------------------
MAV_2475|M.avium_104 ILLMIGIGADDRIHTIDITGDPERIRRAALALPPAVRFRNITT