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VTLDSFAQSAVHSAFLEGRPRLLSLAHRLLGSAHDAEDAVQTAWLRVAATPGPRDIANPSAWLTTVVTRV CLDQLRDRSRRDVLSRRVQPVQTVAYAADEEFLHREDVARALMVLLGRLTPAQRAAYVLHDLFAVPFDRV ADILGVTPAGAKKHASRARARLRPVEPPSTGAPGDAVDREVVDAFLRAAGGGDIVRMVALMAPDAVRIVD PELLPTGTAAVVTGATAIAEETRHFADRIRASVRMRVSGREAHIIAPGGHPLGIIDIRCSGGLITGITIT PVCAADVLEPAAQPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4710 | - | - | 100% (295) | ECF subfamily RNA polymerase sigma-24 factor |
| M. vanbaalenii PYR-1 | Mvan_1575 | - | 4e-31 | 40.27% (226) | RNA polymerase sigma factor SigJ |
| M. vanbaalenii PYR-1 | Mvan_4999 | - | 2e-24 | 31.80% (283) | ECF subfamily RNA polymerase sigma-24 factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 4e-30 | 41.86% (215) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_1191 | - | 1e-74 | 55.72% (271) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 4e-30 | 41.86% (215) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | MLBr_01076 | sigE | 1e-10 | 30.06% (163) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_4733 | - | 4e-73 | 52.24% (268) | putative RNA polymerase sigma factor |
| M. marinum M | MMAR_3687 | - | 1e-40 | 38.21% (280) | alternative RNA polymerase sigma factor SigJ-like protein |
| M. avium 104 | MAV_2475 | - | 7e-49 | 46.06% (254) | RNA polymerase sigma factor |
| M. smegmatis MC2 155 | MSMEG_1666 | - | 2e-29 | 38.89% (216) | RNA polymerase sigma factor SigJ |
| M. thermoresistible (build 8) | TH_1144 | - | 5e-21 | 27.68% (271) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 1e-40 | 38.21% (280) | alternative RNA polymerase sigma factor SigJ- like |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3361c|M.bovis_AF2122/97 ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
Rv3328c|M.tuberculosis_H37Rv ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
MSMEG_1666|M.smegmatis_MC2_155 --------MTTAARTDQFEALRPHLLAVAYRLTGTYADAEDIVQEAWIRW
TH_1144|M.thermoresistible__bu VTVGSAAGAADGEHAERFTLLRPLLFTIAYEILGSATEADDVLQDGYLRW
Mvan_4710|M.vanbaalenii_PYR-1 ---MTLDSFAQSAVHSAFLEGRPRLLSLAHRLLGSAHDAEDAVQTAWLRV
Mflv_1191|M.gilvum_PYR-GCK -----------MITPSVFEATRPQLTAMAFRMLGSIHDAEDAVQSAWIKA
MAB_4733|M.abscessus_ATCC_1997 -----------MDLIEKFEAERPRLLSVAHRILGSRHDAEDAVQSAWIRA
MAV_2475|M.avium_104 ----MNAPRNLAELAQRFDDDRRHLRSVAFQLLGSLADADDAVQSAWLKA
MMAR_3687|M.marinum_M --------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRL
MUL_3630|M.ulcerans_Agy99 --------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRL
MLBr_01076|M.leprae_Br4923 -MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSP
: . ..:* : :
Mb3361c|M.bovis_AF2122/97 DSQDT------VIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
Rv3328c|M.tuberculosis_H37Rv DSPDT------VIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
MSMEG_1666|M.smegmatis_MC2_155 AGQEA------PIENLQAWLTTVVSRLGLDRLRSAAHRRESYYGEWLPEP
TH_1144|M.thermoresistible__bu SQVDLG-----TVRDTKAFLAQLITREALKVLRTRSRRREDYVGPWLPEP
Mvan_4710|M.vanbaalenii_PYR-1 AATP----GPRDIANPSAWLTTVVTRVCLDQLRDRSRRDVLSRRV-----
Mflv_1191|M.gilvum_PYR-GCK SIT-----ATDDLRNPAAYLTTVLTRECVDQLRMRQRRREEPLAA-----
MAB_4733|M.abscessus_ATCC_1997 QSA-----APNRVDNAPGWLTTVTARLCLDQLRARERHGEVPLTA-----
MAV_2475|M.avium_104 SRA-----DFAAVDNLSGWFTTITAREALDQLRARKRRAELPLAAPEELD
MMAR_3687|M.marinum_M NATTDRPQGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDP
MUL_3630|M.ulcerans_Agy99 NATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDP
MLBr_01076|M.leprae_Br4923 TIMSHP-----PPSRDDDWVEPFDALQGTAVFDATG--------------
:. . : :
Mb3361c|M.bovis_AF2122/97 VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
Rv3328c|M.tuberculosis_H37Rv VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
MSMEG_1666|M.smegmatis_MC2_155 VVTGIDGNDPLNAVVAGEDARFAAMVVLEQLSPDQRVAFVLYDGFGVPFP
TH_1144|M.thermoresistible__bu LL--LEDHDPESDVVLAESVSMAMLVLLETLSPDERAVFVLREVFDFDYD
Mvan_4710|M.vanbaalenii_PYR-1 QPVQTVAYAADEEFLHREDVARALMVLLGRLTPAQRAAYVLHDLFAVPFD
Mflv_1191|M.gilvum_PYR-GCK DMIPADTVAADEHYLRRESISRALMVVLDRLTPSQRVAYVLHDVFAVPFQ
MAB_4733|M.abscessus_ATCC_1997 EHISDTQFAADEEFLRREEVSRAVLVVLDELSPKQRVAYVLHDLFAVPFG
MAV_2475|M.avium_104 RLAVAASSPADEDTLLAESVSTALLVVLDRLSPAQRVAFVLHDVFAMPFE
MMAR_3687|M.marinum_M IVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFD
MUL_3630|M.ulcerans_Agy99 IVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFD
MLBr_01076|M.leprae_Br4923 ----DKATMPSWEELVRQHAARVYWLAYRLSGNQHDAEDLTQETFIRVFR
. : : . : . : : * :
Mb3361c|M.bovis_AF2122/97 EVAEVLGTSEAAARQLASRARKAVTAQ---PALISGDPDPAHNEVVGRLM
Rv3328c|M.tuberculosis_H37Rv EVAEVLGTSEAAARQLASRARKAVTAQ---PALISGDPDPAHNEVVGRLM
MSMEG_1666|M.smegmatis_MC2_155 DIADVLGVSAASARQLASRARRAVADA---PPPVD---DNTHNEIAGALM
TH_1144|M.thermoresistible__bu EIAGAVGKSVPAVRQVAHRSREHVRAR---RKRFDPVPAAQTTELAEEFI
Mvan_4710|M.vanbaalenii_PYR-1 RVADILGVTPAGAKKHASRARARLRPVEPPSTGAPGD--AVDREVVDAFL
Mflv_1191|M.gilvum_PYR-GCK EIAETLGTSPASAKKHASRARERIHRTVQIPAAAT-----IDSAVVEAFL
MAB_4733|M.abscessus_ATCC_1997 DIAAVLDTTAVSAKKLASRARARLGAADPERAREVG----SQLEIVEAFL
MAV_2475|M.avium_104 TIAELLNRSPDAAKKLASRARARLHAAPAGPPRRDGHRIERHVEVVQAFL
MMAR_3687|M.marinum_M QIAPILERTPEATRKLASRARRRIERAEPFPDRDLC----AQREVVDAFF
MUL_3630|M.ulcerans_Agy99 QIAPILERTPEATRKLASRARRRIERAEPFPDRDLC----AQREVVDAFF
MLBr_01076|M.leprae_Br4923 SVQNYQPGTFEG----------------------------WLHRITTNLF
: : . :. ::
Mb3361c|M.bovis_AF2122/97 AAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLV
Rv3328c|M.tuberculosis_H37Rv AAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLV
MSMEG_1666|M.smegmatis_MC2_155 AALAAGDMDGVVRLLHPDVTFTGDSNRKAPTAPRVIHGPEKVARFLFGLA
TH_1144|M.thermoresistible__bu HAATTGDLDRLLSLLAPGATFTTDHGGKAPAVARPVEGAKKVANLVMGFF
Mvan_4710|M.vanbaalenii_PYR-1 RAAGGGDIVRMVALMAPDAVRIVDPELLPTGTAAVVTGATAIAEETRHFA
Mflv_1191|M.gilvum_PYR-GCK AAAAGGDTATMVALMADDCVRVADPTLLPAHTPAVVIGDSAVADETSLFI
MAB_4733|M.abscessus_ATCC_1997 SAARGGDIERLITLMAPDVIRTVDHTLIPSGAATLVRGAQAVAEETRSFT
MAV_2475|M.avium_104 AASRGGDIAALLQLLAADVLRTVDPVLVPADVPTALRGATRVAQETRRFA
MMAR_3687|M.marinum_M AAGRSGNFERLVSVLHPDVVLRGD--FGPNTPRFRAQGAATVAKLARSYA
MUL_3630|M.ulcerans_Agy99 AAGRSGNFERLVSVLHPDVVLRGD--FGPNTPRFRAQGAATVAKLARSYA
MLBr_01076|M.leprae_Br4923 LDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDSLP
: : . . :
Mb3361c|M.bovis_AF2122/97 QRYGPGLFGANQLALVNGELGAYTAGLPGVDGYR-AMAPRITAITVRDGK
Rv3328c|M.tuberculosis_H37Rv QRYGPGLFGANQLALVNGELGAYTAGLPGVDGYR-AMAPRITAITVRDGK
MSMEG_1666|M.smegmatis_MC2_155 RRYGPNWLAGAQLALINGELGTYTPGAPAGDGYP-ELLPRITAMTVRDGK
TH_1144|M.thermoresistible__bu RNR--HRVPDLRLEATN------CNHAPAVLVYTGDHLEAVVLLEIVDGA
Mvan_4710|M.vanbaalenii_PYR-1 DRI-----RASVRMRVSG-------REAHIIAPGGHPLGIIDIRC-SGGL
Mflv_1191|M.gilvum_PYR-GCK DRI-----RVSAPMLVDG-------RTVHVIAPGGHELAVIDITV-TDGR
MAB_4733|M.abscessus_ATCC_1997 DRI-----AVAAILLIDG-------RVGAVIAPGGHPFALIRMDT-DGRL
MAV_2475|M.avium_104 GRA-----RAGAVMLIDG-------TPGIVIAARGRAQILLMIGIGADDR
MMAR_3687|M.marinum_M GPE-----RTVLNALVNG-------AAGAVISISEQASAVMGFLV-RNGR
MUL_3630|M.ulcerans_Agy99 GPE-----RTVLNTLVNG-------AAGAVISISEQASAVMRFLV-RNGR
MLBr_01076|M.leprae_Br4923 PEFR----AAVVLCDIEG------LSYEEIGATLGVKLGTVRSRIHRGRQ
. : .
Mb3361c|M.bovis_AF2122/97 VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN---------------
Rv3328c|M.tuberculosis_H37Rv VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN---------------
MSMEG_1666|M.smegmatis_MC2_155 VCAVWDVANPDKFTGSPLGTAVRRP------------------------
TH_1144|M.thermoresistible__bu ITNLYATRNPDKLAAVAAPRTITR-------------------------
Mvan_4710|M.vanbaalenii_PYR-1 ITGITITPVCAADVLEPAAQPA---------------------------
Mflv_1191|M.gilvum_PYR-GCK IARIEITRTHPSGRR----------------------------------
MAB_4733|M.abscessus_ATCC_1997 VTCIDIAPYTSGDAALSLIATAGSKVSYSPGESGRRIDPRGSGLPRVDH
MAV_2475|M.avium_104 IHTIDITGDPERIRRAALALPPAVRFRNITT------------------
MMAR_3687|M.marinum_M IAAIDVLADPQRIATLDISGLSGPGG-----------------------
MUL_3630|M.ulcerans_Agy99 IAAIDVLADPQRIATLDISGLSGPGG-----------------------
MLBr_01076|M.leprae_Br4923 ALRDYLLTAHPRDGATTDATHVKSA------------------------