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MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNADDLTQETFLRAIGAIERFSGH SSGRTWLLAIARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDLVEVTTMIANLATEQREALLL TQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADTEHNHLTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01448 | - | - | 100% (184) | RNA polymerase sigma factor SigC |
| M. leprae Br4923 | MLBr_01076 | sigE | 4e-11 | 28.09% (178) | RNA polymerase sigma factor SigE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2095 | sigC | 2e-78 | 81.22% (181) | RNA polymerase sigma factor SigC |
| M. gilvum PYR-GCK | Mflv_2200 | - | 6e-12 | 29.78% (178) | RNA polymerase sigma factor SigE |
| M. tuberculosis H37Rv | Rv2069 | sigC | 2e-78 | 81.22% (181) | RNA polymerase sigma factor SigC |
| M. abscessus ATCC 19977 | MAB_3428c | - | 6e-53 | 58.43% (178) | RNA polymerase sigma-C factor |
| M. marinum M | MMAR_3051 | sigC | 1e-74 | 78.26% (184) | RNA polymerase sigma factor, SigC |
| M. avium 104 | MAV_2426 | - | 3e-81 | 83.15% (184) | RNA polymerase sigma factor SigC |
| M. smegmatis MC2 155 | MSMEG_3296 | - | 8e-11 | 30.19% (159) | ECF-family protein sigma factor H |
| M. thermoresistible (build 8) | TH_1729 | sigC | 8e-54 | 60.67% (178) | PROBABLE RNA POLYMERASE SIGMA FACTOR, ECF SUBFAMILY, SIGC |
| M. ulcerans Agy99 | MUL_2295 | sigC | 9e-75 | 78.26% (184) | RNA polymerase sigma factor SigC |
| M. vanbaalenii PYR-1 | Mvan_2297 | - | 3e-12 | 32.41% (145) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 MTPGEGPDLVDKIMASIGEQPTGRPAWMRWLRSHYRRWGLIGVGLFQVAI
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_3296|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 AAAQISGIDFGMVAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPAS
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_3296|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 ASGVAAITGVYSVALLGYVIVDAFDGEVTATRIASHMPLLLGLAFALLVA
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_3296|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK ---------------------------------------MTEGARTDTVR
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
MAV_2426|M.avium_104 RERVGSRRPGSSDATADAGFAAWAADAPAGRRRGHLRPINRAAPDPTASS
Mb2095|M.bovis_AF2122/97 --------------------------------------------------
Rv2069|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3051|M.marinum_M --------------------------------------------------
MUL_2295|M.ulcerans_Agy99 --------------------------------------------------
MAB_3428c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1729|M.thermoresistible__bu --------------------------------------------------
MSMEG_3296|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2297|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2200|M.gilvum_PYR-GCK TARIDSARSRNENASARVAEHDGSPQGGPHHHLEDPTTTTQAPTSSVSAA
MLBr_01448|M.leprae_Br4923 -----------------MIASSGDEAVTDLALAAARGSK-------RALE
MAV_2426|M.avium_104 TTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNA-------RALE
Mb2095|M.bovis_AF2122/97 ----------------MTATASDDEAVTALALSAAKGNG-------RALE
Rv2069|M.tuberculosis_H37Rv ----------------MTATASDDEAVTALALSAAKGNG-------RALE
MMAR_3051|M.marinum_M -----------------MTTSPDDEAVTALALAAADGDA-------RAFE
MUL_2295|M.ulcerans_Agy99 ---------------MPMTTSPDDEAVTALALAAADGDA-------RAFE
MAB_3428c|M.abscessus_ATCC_199 -----------------MATGTDDEQLLELALSAGRGDQ-------SALE
TH_1729|M.thermoresistible__bu ------------------VGLRDDDRVTRLALAAGRGDP-------AALE
MSMEG_3296|M.smegmatis_MC2_155 ----------------MIREEFPGERRPD-------------------FQ
Mvan_2297|M.vanbaalenii_PYR-1 ----------------MRRSSIQWNQQPDNLFGGPVMDSPPEDTVLQRFE
Mflv_2200|M.gilvum_PYR-GCK APVAAPVAAPVSMAHREQFTEAEWVEPTDELTGTAVFDATGDKAAMPSWD
:
MLBr_01448|M.leprae_Br4923 AFIKATQQDVWR-FVAYLSDVGNADDLTQETFLRAIGAIERFSGHSSGRT
MAV_2426|M.avium_104 AFIKATQQDVWR-FVAYLCDAGSADDLTQETFLRAIGAIERFSGRSSART
Mb2095|M.bovis_AF2122/97 AFIKATQQDVWR-FVAYLSDVGSADDLTQETFLRAIGAIPRFSARSSART
Rv2069|M.tuberculosis_H37Rv AFIKATQQDVWR-FVAYLSDVGSADDLTQETFLRAIGAIPRFSARSSART
MMAR_3051|M.marinum_M AFIKATQQDVWR-FVAYLSDAGSADDLTQETFLRAIGAIRRFGGRSSART
MUL_2295|M.ulcerans_Agy99 AFIKATQQDVWR-FVAYLSDAGSADDLTQETFLRAIGAIRRFGGRSSART
MAB_3428c|M.abscessus_ATCC_199 SLVKATQGDVWR-FVAYLADSGVADDLTQETYLRALGALPRFAGRSTVRT
TH_1729|M.thermoresistible__bu QFIRATQRDVWR-TVAYLADPGSADDLTQETFLRAIRSLPKFNGRSSART
MSMEG_3296|M.smegmatis_MC2_155 DEVKPLLGDLHRRAYAYVRDTSDAEDLVQETLLRAYRAFDRLGDDYQLMP
Mvan_2297|M.vanbaalenii_PYR-1 RDVLPLLDQLYRAARRYTGSVADAEDLVQETMVKAYGGFHRFEDGTNVRA
Mflv_2200|M.gilvum_PYR-GCK ELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPG-TFEG
: : * . *:**.*** ::. .. .
MLBr_01448|M.leprae_Br4923 WLLAIARRVVADHIRRAQTRPRTTFDGYPERMLNADRHARGFEDLV----
MAV_2426|M.avium_104 WLLSIARRVVADHIRHLQSRPRAAVGADPEHVLRTDRHARGFEDLV----
Mb2095|M.bovis_AF2122/97 WLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARGFEDLV----
Rv2069|M.tuberculosis_H37Rv WLLAIARHVVADHIRHVRSRPRTTRGARPEHLIDGDRHARGFEDLV----
MMAR_3051|M.marinum_M WLLAIARRVVADHIRHLQARPRAAHGVDPELLLDRGRRARGFEDLV----
MUL_2295|M.ulcerans_Agy99 WLLAIARRVVADHIRHLQARPRAAHGVDPELLLDRGRRARGFEDLV----
MAB_3428c|M.abscessus_ATCC_199 WLLSIARRVVADHIRHLKSRPRIAHGADLEEASLR-RPTHRFEELV----
TH_1729|M.thermoresistible__bu WLLSIARRVVVDQIRHNQSRPRTSYAVDVHTVLDKRRPDGRFEDIV----
MSMEG_3296|M.smegmatis_MC2_155 WLLAIMRNTWISRYRAAQRRPAEALVGEFLDTYAETASRGASGETWSAED
Mvan_2297|M.vanbaalenii_PYR-1 WLLRIMTNTWIKSYRRAQCRPEEVLSEDITDAQLAGHGRHSSTGLPSAEL
Mflv_2200|M.gilvum_PYR-GCK WLHRITTNLFLDMVRRRGRIRMEALPEDYDRVPADEPNPEQIYHDSRLG-
** * . . *
MLBr_01448|M.leprae_Br4923 ---------EVTTMIANLATEQREALLLTQLLGLPYADAAAVCGCPVGTI
MAV_2426|M.avium_104 ---------EVTTMIAGLNPEQREALLLTQLLGLPYADAAAVCGCPVGTI
Mb2095|M.bovis_AF2122/97 ---------EVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTI
Rv2069|M.tuberculosis_H37Rv ---------EVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTI
MMAR_3051|M.marinum_M ---------EVTTMIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTI
MUL_2295|M.ulcerans_Agy99 ---------EVTTMIAQLTSDQREALLLTQLLGLSYTDAAAVCGCPVGTI
MAB_3428c|M.abscessus_ATCC_199 ---------ELKSLLAALDDDRREALVLTQVVGLSYAETADVCGCAIGTI
TH_1729|M.thermoresistible__bu ---------EIKLLLDGLDTDRRHALLLTQVLGLSYAEAAEVCGCAVGTI
MSMEG_3296|M.smegmatis_MC2_155 VAMRNMSDPAVVAALSKLPESLRLTMYYTAIVGMSCREVSTLMDIPKGTV
Mvan_2297|M.vanbaalenii_PYR-1 AALEALGDDEVRDALGRLREDQRLVVYYADVEGLRYKEIALILDIPVGTV
Mflv_2200|M.gilvum_PYR-GCK --------ADLQAALDSLAPEFRAAVVLCDIEGLSYEEIGATLGVKLGTV
: : * . * .: : *: : . . **:
MLBr_01448|M.leprae_Br4923 RSRVARARDALLADTEHNHLTG---------
MAV_2426|M.avium_104 RSRVARARDALLADGERNDLTG---------
Mb2095|M.bovis_AF2122/97 RSRVARARDALLADAEPDDLTG---------
Rv2069|M.tuberculosis_H37Rv RSRVARARDALLADAEPDDLTG---------
MMAR_3051|M.marinum_M RSRVARARDALLADNERDDLTG---------
MUL_2295|M.ulcerans_Agy99 RSRVARARDALLADNERDDLTG---------
MAB_3428c|M.abscessus_ATCC_199 RSRVARARDELIGWAEPENLTG---------
TH_1729|M.thermoresistible__bu RSRVARARDDLLQQARPVDRTG---------
MSMEG_3296|M.smegmatis_MC2_155 MSRLHRGRHQMRRALSHHRS-----------
Mvan_2297|M.vanbaalenii_PYR-1 MSRLHRGRRALRSLLVDVATARGYLRDAAAA
Mflv_2200|M.gilvum_PYR-GCK RSRIHRGRQALRDHLARHSDVGAGRDTAKSA
**: *.* :