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MAVLGAQAASTFESLRPHLMSVAYRLTGTVADAEDIVQEAWLRWDAAPGRDDVADLRAWLTTVVSRLGLD KLRSAARRRETYTGHWLPEPVVTGLGDAGGADPLSAVVAAEDARFAVMVVLERLSPDQRVAFVLHDGFAM PFAEVAGVIGASEAAARQLASRARKAVAAAPPPQPDPTHNEVVGRLMAAMASGDLHSVVSLLHPDVTFTG DANGRAPTAARVICGADKVARFMLGLARRYGPAFYTANQLALVNGELGSYTLGTAGDGGHWAMLPRITAM TVRDGKVCALWDIANPDKFSGSPLRDLVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1196 | sigJ | - | 100% (309) | alternative RNA polymerase sigma factor SigJ |
| M. marinum M | MMAR_3687 | - | 3e-42 | 38.89% (306) | alternative RNA polymerase sigma factor SigJ-like protein |
| M. marinum M | MMAR_4487 | - | 3e-41 | 33.22% (295) | alternative RNA polymerase sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 1e-127 | 77.67% (300) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_4852 | - | 1e-109 | 69.73% (294) | RNA polymerase sigma factor SigJ |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 1e-127 | 77.67% (300) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | MLBr_01448 | - | 6e-09 | 29.30% (157) | RNA polymerase sigma factor SigC |
| M. abscessus ATCC 19977 | MAB_3678c | - | 1e-106 | 63.07% (306) | RNA polymerase sigma factor SigJ |
| M. avium 104 | MAV_4301 | - | 1e-133 | 78.60% (299) | RNA polymerase sigma factor SigJ |
| M. smegmatis MC2 155 | MSMEG_1666 | - | 1e-116 | 69.21% (302) | RNA polymerase sigma factor SigJ |
| M. thermoresistible (build 8) | TH_1142 | - | 1e-45 | 36.67% (300) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 7e-42 | 38.56% (306) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_1575 | - | 1e-110 | 69.15% (295) | RNA polymerase sigma factor SigJ |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3361c|M.bovis_AF2122/97 --------------------MEVSEFEALRQHLMSVAYRLTG---TVADA
Rv3328c|M.tuberculosis_H37Rv --------------------MEVSEFEALRQHLMSVAYRLTG---TVADA
MAV_4301|M.avium_104 MSLVSLTPGPMAYARFMTSAQQVSEFESLRPHLMSVAYRLTG---TVADA
MMAR_1196|M.marinum_M --------------MAVLGAQAASTFESLRPHLMSVAYRLTG---TVADA
Mflv_4852|M.gilvum_PYR-GCK ------MPHGGIYTRRMTASARVAEFEQMRPHLLSVAYRLTG---TVADA
Mvan_1575|M.vanbaalenii_PYR-1 ----------------MTTSARVGEFEQLRPHLLSVAYRLTG---TLADA
MSMEG_1666|M.smegmatis_MC2_155 ----------------MTTAARTDQFEALRPHLLAVAYRLTG---TYADA
MAB_3678c|M.abscessus_ATCC_199 --------------MVVRAGDRTDEFEALRPRLQAVAYRLTG---SVADA
MUL_3630|M.ulcerans_Agy99 ----------------MTDPALLARFQAARPRLGALAYRMLG---SLADA
TH_1142|M.thermoresistible__bu --------MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILG---SATEA
MLBr_01448|M.leprae_Br4923 -MIASSGDEAVTDLALAAARGSKRALEAFIKATQQDVWRFVAYLSDVGNA
: .:.: . :*
Mb3361c|M.bovis_AF2122/97 EDIVQEAWLRWDSQDT------VIADPRAWLTTVVSRLGLDKLRSAAHRR
Rv3328c|M.tuberculosis_H37Rv EDIVQEAWLRWDSPDT------VIADPRAWLTTVVSRLGLDKLRSAAHRR
MAV_4301|M.avium_104 EDIVQDAWLRWHGQDG------AITDLRAWLTTVVSRLGLDRLRSATHRR
MMAR_1196|M.marinum_M EDIVQEAWLRWDAAPGRD----DVADLRAWLTTVVSRLGLDKLRSAARRR
Mflv_4852|M.gilvum_PYR-GCK EDIVQDAWLRWSTHRGA-----AVEDLKAWLTTVVSRLALDKLRSAAHRR
Mvan_1575|M.vanbaalenii_PYR-1 EDIVQDAWLRWEANSAT-----VIEDLKAWLTTVVSRLALDRLRSAAHRR
MSMEG_1666|M.smegmatis_MC2_155 EDIVQEAWIRWAG-QEA-----PIENLQAWLTTVVSRLGLDRLRSAAHRR
MAB_3678c|M.abscessus_ATCC_199 EDIVQDAWLRLYSTTA------EIEDLAAWLTTVVSRLGLDRLRSAVYRR
MUL_3630|M.ulcerans_Agy99 EDVVQEAWLRLNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRG
TH_1142|M.thermoresistible__bu DDVLQESYLRWAEVDLA-----AVRDTKSYLAKLVSRQALNALRAGARRR
MLBr_01448|M.leprae_Br4923 DDLTQETFLRAIGAIERFS---GHSSGRTWLLAIARRVVADHIRRAQTRP
:*: *::::* . ::* :. * : :* *
Mb3361c|M.bovis_AF2122/97 ETYTGTWLPEPVVTGLD---ATDPLAAVVAAEDARFAAMVVLERLRPDQR
Rv3328c|M.tuberculosis_H37Rv ETYTGTWLPEPVVTGLD---ATDPLAAVVAAEDARFAAMVVLERLRPDQR
MAV_4301|M.avium_104 ETYTGNWLPEPVVTGLGPHSGADPLAAVVAGEDARFAAMVVLERLSPDQR
MMAR_1196|M.marinum_M ETYTGHWLPEPVVTGLGDAGGADPLSAVVAAEDARFAVMVVLERLSPDQR
Mflv_4852|M.gilvum_PYR-GCK ETYVGEWLPEPVVTGLD---GRDPLSALVADEDARFAAMVVLENLTPDQR
Mvan_1575|M.vanbaalenii_PYR-1 ETYVGEWLPEPVVTGFD---GVDPLASVVAGEDARFAAMVVLENLTPDQR
MSMEG_1666|M.smegmatis_MC2_155 ESYYGEWLPEPVVTGID---GNDPLNAVVAGEDARFAAMVVLEQLSPDQR
MAB_3678c|M.abscessus_ATCC_199 ETYVGEWLPEPVVTGLD---GDDPLAALVASEDARFAAMVVLDRLAPDQR
MUL_3630|M.ulcerans_Agy99 REELVGQLPDPIVDGVA---AFDPEHHAMLADAVGLALFVVLDTLAPAER
TH_1142|M.thermoresistible__bu EDYVGPWLPEPLLLEER-----DASADVVLAESVSMAMMVVLESLTPDER
MLBr_01448|M.leprae_Br4923 RTTFDG-YPERMLNADR----------HARGFEDLVEVTTMIANLATEQR
. *: :: . .:: * . :*
Mb3361c|M.bovis_AF2122/97 VAFVLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPD
Rv3328c|M.tuberculosis_H37Rv VAFVLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPD
MAV_4301|M.avium_104 VAFVLHDGFAVPFSEVAEVLGTSEAAARQLASRARKVVSAQP---PPEPD
MMAR_1196|M.marinum_M VAFVLHDGFAMPFAEVAGVIGASEAAARQLASRARKAVAAAP---PPQPD
Mflv_4852|M.gilvum_PYR-GCK VAFVLHDGFAVPFSAIAEVLGTSTQAARQLASRARRAVSSAP---PPAAD
Mvan_1575|M.vanbaalenii_PYR-1 VAFVLHDGFAVPFAEIAEVLGSSPESARQLASRARRAASAAP---PPADE
MSMEG_1666|M.smegmatis_MC2_155 VAFVLYDGFGVPFPDIADVLGVSAASARQLASRARRAVADAP---PPVDD
MAB_3678c|M.abscessus_ATCC_199 VAFVLHDGFSVPFKQIADILGISDAAARQLASRARRMVTATP---EPVAD
MUL_3630|M.ulcerans_Agy99 LAFVLHDVFAVPFDQIAPILERTPEATRKLASRARRRIERAEP-FPDRDL
TH_1142|M.thermoresistible__bu AVFVLREVFGFEYGEIATTVGKSVTAVRQIAHRARSHVHARRKRFEPVDP
MLBr_01448|M.leprae_Br4923 EALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADT--------
.::* : :.. : * . : *. . ***
Mb3361c|M.bovis_AF2122/97 PAHNEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGS
Rv3328c|M.tuberculosis_H37Rv PAHNEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGS
MAV_4301|M.avium_104 PSHDEVVGQLMAAMAAGNLEAVVALLHPDVMFTGDSNGKAPTAVQVIHGA
MMAR_1196|M.marinum_M PTHNEVVGRLMAAMASGDLHSVVSLLHPDVTFTGDANGRAPTAARVICGA
Mflv_4852|M.gilvum_PYR-GCK --HAEVVGKLLAAMASGDLTAVVSLLHPDVTFTGDSNRRAPTAARVIRGS
Mvan_1575|M.vanbaalenii_PYR-1 --HAEVVGKLLAAMASGDLTEVVAVLHPDVTFTGDSNRRAPTAARVIHGS
MSMEG_1666|M.smegmatis_MC2_155 NTHNEIAGALMAALAAGDMDGVVRLLHPDVTFTGDSNRKAPTAPRVIHGP
MAB_3678c|M.abscessus_ATCC_199 AEHNEVVGELLEALMSGSVEAVVRLLHPDVTMTGDSDGKAPTAVRVIHGP
MUL_3630|M.ulcerans_Agy99 CAQREVVDAFFAAGRSGNFERLVSVLHPDVVLRGDFGPNTPRFR--AQGA
TH_1142|M.thermoresistible__bu EVSMEITERFLTAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGA
MLBr_01448|M.leprae_Br4923 -EHNHLTG------------------------------------------
.:.
Mb3361c|M.bovis_AF2122/97 DKVVRFILGLVQRYGPG-LFGANQLALVNGELGAYTAGLPGVDGYRAMAP
Rv3328c|M.tuberculosis_H37Rv DKVVRFILGLVQRYGPG-LFGANQLALVNGELGAYTAGLPGVDGYRAMAP
MAV_4301|M.avium_104 DKVVRFMLGLARRYGPG-FYSAYQLGLVNGELGIYTAGLPGGDGYREMCP
MMAR_1196|M.marinum_M DKVARFMLGLARRYGPA-FYTANQLALVNGELGSYTLGTAGDGGHWAMLP
Mflv_4852|M.gilvum_PYR-GCK DKVARFLLGLGAKYGPERLLAGSELGLVNGELGVYSPGADATPDAPRIMP
Mvan_1575|M.vanbaalenii_PYR-1 DKVARFLLGLARRYGEQRFFGSGVLGMVNGELGVYTMGAPATEDAPAIAP
MSMEG_1666|M.smegmatis_MC2_155 EKVARFLFGLARRYGPN-WLAGAQLALINGELGTYTPGAPAGDGYPELLP
MAB_3678c|M.abscessus_ATCC_199 DKVARFLLGLMERYGPQ-MTQAINPALVNGQFGMYLTETDTDPNFRPVLP
MUL_3630|M.ulcerans_Agy99 ATVAKLAR---SYAGPE---RTVLNTLVNGAAGAVIS-------ISEQAS
TH_1142|M.thermoresistible__bu EKVAAVILG--------IFRAGQRLPDVRIETAIYNCAPAVVVYSRDNLE
MLBr_01448|M.leprae_Br4923 --------------------------------------------------
Mb3361c|M.bovis_AF2122/97 RITAITVRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
Rv3328c|M.tuberculosis_H37Rv RITAITVRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
MAV_4301|M.avium_104 RIMAMTVREGKVCALWDIANPDKFTGSPL--------GR------
MMAR_1196|M.marinum_M RITAMTVRDGKVCALWDIANPDKFSGSPLRDLVG-----------
Mflv_4852|M.gilvum_PYR-GCK RIQALAVRDGLVVAIYDVANPDKFTASPLAR--------------
Mvan_1575|M.vanbaalenii_PYR-1 RIQALTVHRGQVVAIYDIANPDKFTASPLR---------------
MSMEG_1666|M.smegmatis_MC2_155 RITAMTVRDGKVCAVWDVANPDKFTGSPLGTAVRRP---------
MAB_3678c|M.abscessus_ATCC_199 RVSAFTVRDGRVLAVWDVSNPDKFSGTPLREA-------------
MUL_3630|M.ulcerans_Agy99 AVMRFLVRNGRIAAIDVLADPQRIATLDISGLSGPGG--------
TH_1142|M.thermoresistible__bu GVFTVEVVDGRITHFYAVRNPEKLAAVDTPRQISR----------
MLBr_01448|M.leprae_Br4923 ---------------------------------------------