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MNAPRNLAELAQRFDDDRRHLRSVAFQLLGSLADADDAVQSAWLKASRADFAAVDNLSGWFTTITAREAL DQLRARKRRAELPLAAPEELDRLAVAASSPADEDTLLAESVSTALLVVLDRLSPAQRVAFVLHDVFAMPF ETIAELLNRSPDAAKKLASRARARLHAAPAGPPRRDGHRIERHVEVVQAFLAASRGGDIAALLQLLAADV LRTVDPVLVPADVPTALRGATRVAQETRRFAGRARAGAVMLIDGTPGIVIAARGRAQILLMIGIGADDRI HTIDITGDPERIRRAALALPPAVRFRNITT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2475 | - | - | 100% (310) | RNA polymerase sigma factor |
| M. avium 104 | MAV_2018 | - | 2e-48 | 40.07% (297) | RNA polymerase ECF-subfamily protein sigma factor |
| M. avium 104 | MAV_0164 | sigI | 1e-33 | 35.34% (283) | RNA polymerase sigma factor SigI |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 6e-32 | 41.20% (233) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_1191 | - | 8e-56 | 47.25% (273) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 7e-32 | 41.20% (233) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4733 | - | 1e-63 | 50.00% (292) | putative RNA polymerase sigma factor |
| M. marinum M | MMAR_3687 | - | 9e-43 | 40.00% (290) | alternative RNA polymerase sigma factor SigJ-like protein |
| M. smegmatis MC2 155 | MSMEG_6817 | - | 5e-33 | 33.00% (300) | RNA polymerase sigma factor, sigma-70 family protein |
| M. thermoresistible (build 8) | TH_1142 | - | 9e-29 | 31.10% (299) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 3e-43 | 40.69% (290) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_4710 | - | 9e-49 | 46.06% (254) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1191|M.gilvum_PYR-GCK -----------MITPSVFEATRPQLTAMAFRMLGSIHDAEDAVQSAWIKA
Mvan_4710|M.vanbaalenii_PYR-1 ---MTLDSFAQSAVHSAFLEGRPRLLSLAHRLLGSAHDAEDAVQTAWLRV
MAB_4733|M.abscessus_ATCC_1997 -----------MDLIEKFEAERPRLLSVAHRILGSRHDAEDAVQSAWIRA
MAV_2475|M.avium_104 ----MNAPRNLAELAQRFDDDRRHLRSVAFQLLGSLADADDAVQSAWLKA
MMAR_3687|M.marinum_M --------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRL
MUL_3630|M.ulcerans_Agy99 --------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRL
Mb3361c|M.bovis_AF2122/97 ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
Rv3328c|M.tuberculosis_H37Rv ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
MSMEG_6817|M.smegmatis_MC2_155 MT------ARLDDHTERFTMLRPLLFTIAYEILGSVTEADDVLQDSYLNW
TH_1142|M.thermoresistible__bu MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILGSATEADDVLQESYLRW
* * * ::*..: *: :*:* :* :::.
Mflv_1191|M.gilvum_PYR-GCK SIT-----ATDDLRNPAAYLTTVLTRECVDQLRMRQRRREEPLAA-----
Mvan_4710|M.vanbaalenii_PYR-1 AATP----GPRDIANPSAWLTTVVTRVCLDQLRDRSRRDVLSRRV-----
MAB_4733|M.abscessus_ATCC_1997 QSA-----APNRVDNAPGWLTTVTARLCLDQLRARERHGEVPLTA-----
MAV_2475|M.avium_104 SRA-----DFAAVDNLSGWFTTITAREALDQLRARKRRAELPLAAPEELD
MMAR_3687|M.marinum_M NATTDRPQGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDP
MUL_3630|M.ulcerans_Agy99 NATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDP
Mb3361c|M.bovis_AF2122/97 DSQD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
Rv3328c|M.tuberculosis_H37Rv DSPD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
MSMEG_6817|M.smegmatis_MC2_155 AKVDL-----AAVRDTKSYLAQLVTRQALKAQRTSARRRESYVGPWLPEP
TH_1142|M.thermoresistible__bu AEVDL-----AAVRDTKSYLAKLVSRQALNALRAGARRREDYVGPWLPEP
: : .::: : :* :. * :
Mflv_1191|M.gilvum_PYR-GCK DMIPADTVAADEHYLRRESISRALMVVLDRLTPSQRVAYVLHDVFAVPFQ
Mvan_4710|M.vanbaalenii_PYR-1 QPVQTVAYAADEEFLHREDVARALMVLLGRLTPAQRAAYVLHDLFAVPFD
MAB_4733|M.abscessus_ATCC_1997 EHISDTQFAADEEFLRREEVSRAVLVVLDELSPKQRVAYVLHDLFAVPFG
MAV_2475|M.avium_104 RLAVAASSPADEDTLLAESVSTALLVVLDRLSPAQRVAFVLHDVFAMPFE
MMAR_3687|M.marinum_M IVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFD
MUL_3630|M.ulcerans_Agy99 IVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFD
Mb3361c|M.bovis_AF2122/97 VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
Rv3328c|M.tuberculosis_H37Rv VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
MSMEG_6817|M.smegmatis_MC2_155 LL--LDDRDASADVVLAESVSMAMLVVLETLTPDERAVFVLHDVFGFDYA
TH_1142|M.thermoresistible__bu LL--LEERDASADVVLAESVSMAMMVVLESLTPDERAVFVLREVFGFEYG
. : : * :*:* * * :* .:**:: *.. :
Mflv_1191|M.gilvum_PYR-GCK EIAETLGTSPASAKKHASRARERIHRTVQIPAAAT-----IDSAVVEAFL
Mvan_4710|M.vanbaalenii_PYR-1 RVADILGVTPAGAKKHASRARARLRPVEPPSTGAPGD--AVDREVVDAFL
MAB_4733|M.abscessus_ATCC_1997 DIAAVLDTTAVSAKKLASRARARLGAADPERAREVG----SQLEIVEAFL
MAV_2475|M.avium_104 TIAELLNRSPDAAKKLASRARARLHAAPAGPPRRDGHRIERHVEVVQAFL
MMAR_3687|M.marinum_M QIAPILERTPEATRKLASRARRRIERAEPFPDRDLC----AQREVVDAFF
MUL_3630|M.ulcerans_Agy99 QIAPILERTPEATRKLASRARRRIERAEPFPDRDLC----AQREVVDAFF
Mb3361c|M.bovis_AF2122/97 EVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDP---AHNEVVGRLM
Rv3328c|M.tuberculosis_H37Rv EVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDP---AHNEVVGRLM
MSMEG_6817|M.smegmatis_MC2_155 EISEAVGKSTAAVRQIAHRAREHVHARRKRFDPVDSD---QAAEITQQFL
TH_1142|M.thermoresistible__bu EIATTVGKSVTAVRQIAHRARSHVHARRKRFEPVDPE---VSMEITERFL
:: : : ..:: * *** : :. ::
Mflv_1191|M.gilvum_PYR-GCK AAAAGGDTATMVALMADDCVRVADPTLLPAHTPAVVIGDSAVADETSLFI
Mvan_4710|M.vanbaalenii_PYR-1 RAAGGGDIVRMVALMAPDAVRIVDPELLPTGTAAVVTGATAIAEETRHFA
MAB_4733|M.abscessus_ATCC_1997 SAARGGDIERLITLMAPDVIRTVDHTLIPSGAATLVRGAQAVAEETRSFT
MAV_2475|M.avium_104 AASRGGDIAALLQLLAADVLRTVDPVLVPADVPTALRGATRVAQETRRFA
MMAR_3687|M.marinum_M AAGRSGNFERLVSVLHPDVVLRGD--FGPNTPRFRAQGAATVAKLARSYA
MUL_3630|M.ulcerans_Agy99 AAGRSGNFERLVSVLHPDVVLRGD--FGPNTPRFRAQGAATVAKLARSYA
Mb3361c|M.bovis_AF2122/97 AAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLV
Rv3328c|M.tuberculosis_H37Rv AAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLV
MSMEG_6817|M.smegmatis_MC2_155 TAASTGDMAGLVALLAPDVVTITDGGGLPGAARRPLVGAERVAGAIVRGM
TH_1142|M.thermoresistible__bu TAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGAEKVAAVILGIF
* *: :: :: * * . * :.
Mflv_1191|M.gilvum_PYR-GCK DRIRVSAPMLVD-----------GRTVHVIAPGGHELAVIDITV-TDGRI
Mvan_4710|M.vanbaalenii_PYR-1 DRIRASVRMRVS-----------GREAHIIAPGGHPLGIIDIRC-SGGLI
MAB_4733|M.abscessus_ATCC_1997 DRIAVAAILLID-----------GRVGAVIAPGGHPFALIRMDT-DGRLV
MAV_2475|M.avium_104 GRARAGAVMLID-----------GTPGIVIAARGRAQILLMIGIGADDRI
MMAR_3687|M.marinum_M GPERTVLNALVN-----------GAAGAVISISEQASAVMGFLV-RNGRI
MUL_3630|M.ulcerans_Agy99 GPERTVLNTLVN-----------GAAGAVISISEQASAVMRFLV-RNGRI
Mb3361c|M.bovis_AF2122/97 QRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGKV
Rv3328c|M.tuberculosis_H37Rv QRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGKV
MSMEG_6817|M.smegmatis_MC2_155 RR-----DLRFEIVTAN------GAPAVALRTDEDQLLGLVTLEIHDGRI
TH_1142|M.thermoresistible__bu RAGQRLPDVRIETAIYN------CAPAVVVYS-RDNLEGVFTVEVVDGRI
. : : . :
Mflv_1191|M.gilvum_PYR-GCK ARIEITRTHPSGRR----------------------------------
Mvan_4710|M.vanbaalenii_PYR-1 TGITITPVCAADVLEPAAQPA---------------------------
MAB_4733|M.abscessus_ATCC_1997 TCIDIAPYTSGDAALSLIATAGSKVSYSPGESGRRIDPRGSGLPRVDH
MAV_2475|M.avium_104 HTIDITGDPERIRRAALALPPAVRFRNITT------------------
MMAR_3687|M.marinum_M AAIDVLADPQRIATLDISGLSGPGG-----------------------
MUL_3630|M.ulcerans_Agy99 AAIDVLADPQRIATLDISGLSGPGG-----------------------
Mb3361c|M.bovis_AF2122/97 CALWDIANPDKFTGSPLKERRAQPTGRGRHHRN---------------
Rv3328c|M.tuberculosis_H37Rv CALWDIANPDKFTGSPLKERRAQPTGRGRHHRN---------------
MSMEG_6817|M.smegmatis_MC2_155 TSLYAIANPDKLAALDGPRVITR-------------------------
TH_1142|M.thermoresistible__bu THFYAVRNPEKLAAVDTPRQISR-------------------------
: