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M. vanbaalenii PYR-1 Mvan_2419 (-)

annotation: alpha/beta hydrolase fold
coordinates: 2573293 - 2574180
length: 295

TRQEVQIPADGGQIAAYVYRPQVTGGGTACIVMAHGFTGTRDDGLPDYAEAFCAAGHTVVLFDYRHFGAS
TGEPRQLLDIAEQRRDYHTVIAWARHLDGVDPNRIVVWGSSFSGGHVLAVAAEDPRIAAVIAQAPFTDAL
ATLREIPPGNIPLLLIAAVRDQVGAWRGRPPHTVAAVGSPGTVAALTSPDAKPGFEAIIGPNSLWRNEFA
ARLMFTFAFNRPGRKAAKLRMPVLLCVCDDDVVTPPGPSVEAAHRAPRGELCRYPYGHFDIYHDPKVKAD
QLEFLARVVGDRTA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2419--100% (295)alpha/beta hydrolase fold
M. vanbaalenii PYR-1Mvan_1417-2e-4437.62% (303) peptidase S15
M. vanbaalenii PYR-1Mvan_1972-5e-4438.38% (297) alpha/beta hydrolase fold

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2330c-6e-0927.89% (190) hypothetical protein Mb2330c
M. gilvum PYR-GCKMflv_3976-1e-13578.55% (289) dienelactone hydrolase
M. tuberculosis H37RvRv2307c-6e-0927.89% (190) hypothetical protein Rv2307c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2608-6e-4938.70% (292) putative hydrolase, alpha/beta fold
M. marinum MMMAR_0385-8e-6846.74% (291) hypothetical protein MMAR_0385
M. avium 104MAV_2688-1e-0742.62% (61) alpha/beta hydrolase
M. smegmatis MC2 155MSMEG_4450-3e-5840.79% (304) alpha/beta hydrolase
M. thermoresistible (build 8)TH_2570-1e-12269.90% (289) PUTATIVE alpha/beta hydrolase fold
M. ulcerans Agy99MUL_1035-1e-6546.10% (295) hypothetical protein MUL_1035

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_2419|M.vanbaalenii_PYR-1       ------MTRQEVQIPADGGQIAAYVYRPQVTGGG--TACIVMAHGFTGTR
Mflv_3976|M.gilvum_PYR-GCK          -----MPTRDDVRIPAHGDEIAAYVYRPPAGVGA--TACVVMAHGFTGTR
TH_2570|M.thermoresistible__bu      ---MATTDRRDLRIPAHGEQLAAYFYPPAGAGPT--TPCIVMAHGFTATR
MMAR_0385|M.marinum_M               -----MTQRQDVRFPCGEAMISAWLYRPAGADPARPVPMLVMAHGLGAVR
MUL_1035|M.ulcerans_Agy99           -----MTQRQDVRFPCGEALISAWLYRPAGADPARPVPMLVMAHGLGAVR
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      ------MNRQSIRFNSHGIDCEAWLYRAQTVEDT--APIVVMAHGVGGTK
MSMEG_4450|M.smegmatis_MC2_155      MAQPLSYTRDDVTFMSDGTSCAAWLYRPDGVNNP---PIVVLAHGFAAFR
Mb2330c|M.bovis_AF2122/97           ---MSLKRCRALPVVAIVALVASGVITFIWSQQR--RLIYFPSAGPVPSA
Rv2307c|M.tuberculosis_H37Rv        ---MSLKRCRALPVVAIVALVASGVIMFIWSQQR--RLIYFPSAGPVPSA
                                                                                      

Mvan_2419|M.vanbaalenii_PYR-1       DDGLPDYAEAFCAAGHTVVLFDYRHFGASTGEPRQLLDIAEQRRDYHTVI
Mflv_3976|M.gilvum_PYR-GCK          DDGLPDYAEAFRDAGYVVVLFDYRHFGASSGQPRQLLDMARQREDFHTVI
TH_2570|M.thermoresistible__bu      DDGLPAYAEAFHAAGYAVVLFDYRHFGASTGEPRQLLDITRQHDDYRAVV
MMAR_0385|M.marinum_M               TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MUL_1035|M.ulcerans_Agy99           TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      DSGLEPFAVRLAEAGMHALAFDYRGFGASDGFPRQHVSFTHQIGDYHAAV
MSMEG_4450|M.smegmatis_MC2_155      ELRLDAYAARFAQAGYAALVFDYRHWGASDGQPRRILDIPKQQTDWRAAI
Mb2330c|M.bovis_AF2122/97           SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
Rv2307c|M.tuberculosis_H37Rv        SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
                                                                                      

Mvan_2419|M.vanbaalenii_PYR-1       AWARHLDGVDPNRIVVWGSSFSGGHVLAVAAEDPRIAAVIAQAPFTDALA
Mflv_3976|M.gilvum_PYR-GCK          EWARRLDGVDPNRIVAWGSSFSGGHVLAVAAEDPRLAAVIAQAPFTDALA
TH_2570|M.thermoresistible__bu      AWARTQPGVDPDRIVLWGSSFSGGHVLVVAADDPRIAAVISQAPFTDAVP
MMAR_0385|M.marinum_M               AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MUL_1035|M.ulcerans_Agy99           AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      NMARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIA
MSMEG_4450|M.smegmatis_MC2_155      AYARSLDNVDTTRLVGWGSSFGGGHVLTLAARDHEFAAAIVQVPHVSGPA
Mb2330c|M.bovis_AF2122/97           ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS
Rv2307c|M.tuberculosis_H37Rv        ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS
                                                                                      

Mvan_2419|M.vanbaalenii_PYR-1       TLREIPPGNIPLLLIAAVRDQVGAWRGRPPHTVAAVGSPGTVAALTSPDA
Mflv_3976|M.gilvum_PYR-GCK          TLRNAPLRNIPPMVVAALRDQLGAWRNRPPRMLAAVGPPGDLAALTSPDA
TH_2570|M.thermoresistible__bu      TLRKVPPATIARLAVAGLRDQIGSWRGRPPRTASAVGAPGAVAAMTTPDA
MMAR_0385|M.marinum_M               SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA
MUL_1035|M.ulcerans_Agy99           SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      AARSAMTEHSAGTLLRSAVTGLRSRLGRQQRTIPIVGRAGELAALTSDGY
MSMEG_4450|M.smegmatis_MC2_155      SAFSQSPKLVARLIAAGLRDQIGAWFGGAPHRVTSIGRPGEFAMMTSPGA
Mb2330c|M.bovis_AF2122/97           DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG----
Rv2307c|M.tuberculosis_H37Rv        DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG----
                                                                                      

Mvan_2419|M.vanbaalenii_PYR-1       KPGFEAIIGPNS--------LWRNEFAARLMFTFAFNRPGRKAAKLRMPV
Mflv_3976|M.gilvum_PYR-GCK          EPGFGAILGPES--------LWRNEFAARLMLRFAFERPGRKAATLQMPV
TH_2570|M.thermoresistible__bu      EPGFRAIVEPDS--------LWRNEFAARLMLRFPFYRPVRVAGRINAPL
MMAR_0385|M.marinum_M               YPGYLGLMPQGT--------QVPNEVAARIGIKVLGYRPGRSARKIACPI
MUL_1035|M.ulcerans_Agy99           YPGYLGLMPQGT--------QVPNEVAARIGIKVLGYRPGRSARKIACPI
MAV_2688|M.avium_104                ---------------------------------------------MSCPI
MAB_2608|M.abscessus_ATCC_1997      YEAHLAIAGP----------AWRNEIDATVGTQLVSYRPTRCASRIGCPI
MSMEG_4450|M.smegmatis_MC2_155      YELVEEMAGGEAAEHMRAQLEAENDVAARIALRVPLYSPGRHAAKITAPT
Mb2330c|M.bovis_AF2122/97           --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV
Rv2307c|M.tuberculosis_H37Rv        --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV
                                                                                 :  * 

Mvan_2419|M.vanbaalenii_PYR-1       LLCVCDDDVVTPPGPSVEAAHRAPRG----ELCRYPYGHFDIYHD----P
Mflv_3976|M.gilvum_PYR-GCK          LFCVCDDDVVTPPGPTIEAARRAPCG----ELRRYPYGHFDIYHD----P
TH_2570|M.thermoresistible__bu      LVCVCDDDAVTPPEPAIEAARRAPRG----QLRRYPYGHFDIYHD----P
MMAR_0385|M.marinum_M               LFCVCETDSVAPAGPTLRYAARAPRG----EVIRYPEGHFAIYLG-DAFE
MUL_1035|M.ulcerans_Agy99           LFCVCETDSVAPAGPTLRYAARAPRGEVSGEVIRYPEGHFAIYLG-DAFE
MAV_2688|M.avium_104                LFAICENDTVAPAKATQKYAAQAPRG----EIKLYDAGHFDIYVG-ADFE
MAB_2608|M.abscessus_ATCC_1997      LVQIADFDRAAPPHAAAK-AAFKARA----EVRHYPCDHFGVYHGQECHE
MSMEG_4450|M.smegmatis_MC2_155      LVQLATKDDVTPYAKARKIVARIPNG----EVRSYDITHFEPYVD-PHFE
Mb2330c|M.bovis_AF2122/97           LVIAGGSDDIVPATLSEWLVAAAAEPKRYVVVPGVGHNDPELLDG----R
Rv2307c|M.tuberculosis_H37Rv        LVIAGGSDDIVPATLSERLVAAAAEPKRYVVVPGVGHNDPELLDG----R
                                    *.     *  .*   :   .   .       :      .     .     

Mvan_2419|M.vanbaalenii_PYR-1       KVKADQLEFLARVVGDRTA--------
Mflv_3976|M.gilvum_PYR-GCK          QVKADQLEFLHRALARGGR--------
TH_2570|M.thermoresistible__bu      QVKSDQLDFLRQVLGTG----------
MMAR_0385|M.marinum_M               RVVADQLGFLDKHLKPAGQP-------
MUL_1035|M.ulcerans_Agy99           HVVADQLGFLDKHLKPAGQP-------
MAV_2688|M.avium_104                RNVTDQLNFLSRHVPVS----------
MAB_2608|M.abscessus_ATCC_1997      LVIGHQISFLSRHLSIEAVSHTEALHG
MSMEG_4450|M.smegmatis_MC2_155      QIVTDQIDFLNRHVGAGTR--------
Mb2330c|M.bovis_AF2122/97           VMLDAIRRFLTETAVLGQ---------
Rv2307c|M.tuberculosis_H37Rv        VMLDAIRRFLTETAVLGQ---------
                                            ** .