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TRQEVQIPADGGQIAAYVYRPQVTGGGTACIVMAHGFTGTRDDGLPDYAEAFCAAGHTVVLFDYRHFGAS TGEPRQLLDIAEQRRDYHTVIAWARHLDGVDPNRIVVWGSSFSGGHVLAVAAEDPRIAAVIAQAPFTDAL ATLREIPPGNIPLLLIAAVRDQVGAWRGRPPHTVAAVGSPGTVAALTSPDAKPGFEAIIGPNSLWRNEFA ARLMFTFAFNRPGRKAAKLRMPVLLCVCDDDVVTPPGPSVEAAHRAPRGELCRYPYGHFDIYHDPKVKAD QLEFLARVVGDRTA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2419 | - | - | 100% (295) | alpha/beta hydrolase fold |
M. vanbaalenii PYR-1 | Mvan_1417 | - | 2e-44 | 37.62% (303) | peptidase S15 |
M. vanbaalenii PYR-1 | Mvan_1972 | - | 5e-44 | 38.38% (297) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2330c | - | 6e-09 | 27.89% (190) | hypothetical protein Mb2330c |
M. gilvum PYR-GCK | Mflv_3976 | - | 1e-135 | 78.55% (289) | dienelactone hydrolase |
M. tuberculosis H37Rv | Rv2307c | - | 6e-09 | 27.89% (190) | hypothetical protein Rv2307c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2608 | - | 6e-49 | 38.70% (292) | putative hydrolase, alpha/beta fold |
M. marinum M | MMAR_0385 | - | 8e-68 | 46.74% (291) | hypothetical protein MMAR_0385 |
M. avium 104 | MAV_2688 | - | 1e-07 | 42.62% (61) | alpha/beta hydrolase |
M. smegmatis MC2 155 | MSMEG_4450 | - | 3e-58 | 40.79% (304) | alpha/beta hydrolase |
M. thermoresistible (build 8) | TH_2570 | - | 1e-122 | 69.90% (289) | PUTATIVE alpha/beta hydrolase fold |
M. ulcerans Agy99 | MUL_1035 | - | 1e-65 | 46.10% (295) | hypothetical protein MUL_1035 |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_2419|M.vanbaalenii_PYR-1 ------MTRQEVQIPADGGQIAAYVYRPQVTGGG--TACIVMAHGFTGTR Mflv_3976|M.gilvum_PYR-GCK -----MPTRDDVRIPAHGDEIAAYVYRPPAGVGA--TACVVMAHGFTGTR TH_2570|M.thermoresistible__bu ---MATTDRRDLRIPAHGEQLAAYFYPPAGAGPT--TPCIVMAHGFTATR MMAR_0385|M.marinum_M -----MTQRQDVRFPCGEAMISAWLYRPAGADPARPVPMLVMAHGLGAVR MUL_1035|M.ulcerans_Agy99 -----MTQRQDVRFPCGEALISAWLYRPAGADPARPVPMLVMAHGLGAVR MAV_2688|M.avium_104 -------------------------------------------------- MAB_2608|M.abscessus_ATCC_1997 ------MNRQSIRFNSHGIDCEAWLYRAQTVEDT--APIVVMAHGVGGTK MSMEG_4450|M.smegmatis_MC2_155 MAQPLSYTRDDVTFMSDGTSCAAWLYRPDGVNNP---PIVVLAHGFAAFR Mb2330c|M.bovis_AF2122/97 ---MSLKRCRALPVVAIVALVASGVITFIWSQQR--RLIYFPSAGPVPSA Rv2307c|M.tuberculosis_H37Rv ---MSLKRCRALPVVAIVALVASGVIMFIWSQQR--RLIYFPSAGPVPSA Mvan_2419|M.vanbaalenii_PYR-1 DDGLPDYAEAFCAAGHTVVLFDYRHFGASTGEPRQLLDIAEQRRDYHTVI Mflv_3976|M.gilvum_PYR-GCK DDGLPDYAEAFRDAGYVVVLFDYRHFGASSGQPRQLLDMARQREDFHTVI TH_2570|M.thermoresistible__bu DDGLPAYAEAFHAAGYAVVLFDYRHFGASTGEPRQLLDITRQHDDYRAVV MMAR_0385|M.marinum_M TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV MUL_1035|M.ulcerans_Agy99 TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV MAV_2688|M.avium_104 -------------------------------------------------- MAB_2608|M.abscessus_ATCC_1997 DSGLEPFAVRLAEAGMHALAFDYRGFGASDGFPRQHVSFTHQIGDYHAAV MSMEG_4450|M.smegmatis_MC2_155 ELRLDAYAARFAQAGYAALVFDYRHWGASDGQPRRILDIPKQQTDWRAAI Mb2330c|M.bovis_AF2122/97 SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA Rv2307c|M.tuberculosis_H37Rv SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA Mvan_2419|M.vanbaalenii_PYR-1 AWARHLDGVDPNRIVVWGSSFSGGHVLAVAAEDPRIAAVIAQAPFTDALA Mflv_3976|M.gilvum_PYR-GCK EWARRLDGVDPNRIVAWGSSFSGGHVLAVAAEDPRLAAVIAQAPFTDALA TH_2570|M.thermoresistible__bu AWARTQPGVDPDRIVLWGSSFSGGHVLVVAADDPRIAAVISQAPFTDAVP MMAR_0385|M.marinum_M AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA MUL_1035|M.ulcerans_Agy99 AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA MAV_2688|M.avium_104 -------------------------------------------------- MAB_2608|M.abscessus_ATCC_1997 NMARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIA MSMEG_4450|M.smegmatis_MC2_155 AYARSLDNVDTTRLVGWGSSFGGGHVLTLAARDHEFAAAIVQVPHVSGPA Mb2330c|M.bovis_AF2122/97 ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS Rv2307c|M.tuberculosis_H37Rv ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS Mvan_2419|M.vanbaalenii_PYR-1 TLREIPPGNIPLLLIAAVRDQVGAWRGRPPHTVAAVGSPGTVAALTSPDA Mflv_3976|M.gilvum_PYR-GCK TLRNAPLRNIPPMVVAALRDQLGAWRNRPPRMLAAVGPPGDLAALTSPDA TH_2570|M.thermoresistible__bu TLRKVPPATIARLAVAGLRDQIGSWRGRPPRTASAVGAPGAVAAMTTPDA MMAR_0385|M.marinum_M SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA MUL_1035|M.ulcerans_Agy99 SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA MAV_2688|M.avium_104 -------------------------------------------------- MAB_2608|M.abscessus_ATCC_1997 AARSAMTEHSAGTLLRSAVTGLRSRLGRQQRTIPIVGRAGELAALTSDGY MSMEG_4450|M.smegmatis_MC2_155 SAFSQSPKLVARLIAAGLRDQIGAWFGGAPHRVTSIGRPGEFAMMTSPGA Mb2330c|M.bovis_AF2122/97 DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG---- Rv2307c|M.tuberculosis_H37Rv DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG---- Mvan_2419|M.vanbaalenii_PYR-1 KPGFEAIIGPNS--------LWRNEFAARLMFTFAFNRPGRKAAKLRMPV Mflv_3976|M.gilvum_PYR-GCK EPGFGAILGPES--------LWRNEFAARLMLRFAFERPGRKAATLQMPV TH_2570|M.thermoresistible__bu EPGFRAIVEPDS--------LWRNEFAARLMLRFPFYRPVRVAGRINAPL MMAR_0385|M.marinum_M YPGYLGLMPQGT--------QVPNEVAARIGIKVLGYRPGRSARKIACPI MUL_1035|M.ulcerans_Agy99 YPGYLGLMPQGT--------QVPNEVAARIGIKVLGYRPGRSARKIACPI MAV_2688|M.avium_104 ---------------------------------------------MSCPI MAB_2608|M.abscessus_ATCC_1997 YEAHLAIAGP----------AWRNEIDATVGTQLVSYRPTRCASRIGCPI MSMEG_4450|M.smegmatis_MC2_155 YELVEEMAGGEAAEHMRAQLEAENDVAARIALRVPLYSPGRHAAKITAPT Mb2330c|M.bovis_AF2122/97 --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV Rv2307c|M.tuberculosis_H37Rv --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV : * Mvan_2419|M.vanbaalenii_PYR-1 LLCVCDDDVVTPPGPSVEAAHRAPRG----ELCRYPYGHFDIYHD----P Mflv_3976|M.gilvum_PYR-GCK LFCVCDDDVVTPPGPTIEAARRAPCG----ELRRYPYGHFDIYHD----P TH_2570|M.thermoresistible__bu LVCVCDDDAVTPPEPAIEAARRAPRG----QLRRYPYGHFDIYHD----P MMAR_0385|M.marinum_M LFCVCETDSVAPAGPTLRYAARAPRG----EVIRYPEGHFAIYLG-DAFE MUL_1035|M.ulcerans_Agy99 LFCVCETDSVAPAGPTLRYAARAPRGEVSGEVIRYPEGHFAIYLG-DAFE MAV_2688|M.avium_104 LFAICENDTVAPAKATQKYAAQAPRG----EIKLYDAGHFDIYVG-ADFE MAB_2608|M.abscessus_ATCC_1997 LVQIADFDRAAPPHAAAK-AAFKARA----EVRHYPCDHFGVYHGQECHE MSMEG_4450|M.smegmatis_MC2_155 LVQLATKDDVTPYAKARKIVARIPNG----EVRSYDITHFEPYVD-PHFE Mb2330c|M.bovis_AF2122/97 LVIAGGSDDIVPATLSEWLVAAAAEPKRYVVVPGVGHNDPELLDG----R Rv2307c|M.tuberculosis_H37Rv LVIAGGSDDIVPATLSERLVAAAAEPKRYVVVPGVGHNDPELLDG----R *. * .* : . . : . . Mvan_2419|M.vanbaalenii_PYR-1 KVKADQLEFLARVVGDRTA-------- Mflv_3976|M.gilvum_PYR-GCK QVKADQLEFLHRALARGGR-------- TH_2570|M.thermoresistible__bu QVKSDQLDFLRQVLGTG---------- MMAR_0385|M.marinum_M RVVADQLGFLDKHLKPAGQP------- MUL_1035|M.ulcerans_Agy99 HVVADQLGFLDKHLKPAGQP------- MAV_2688|M.avium_104 RNVTDQLNFLSRHVPVS---------- MAB_2608|M.abscessus_ATCC_1997 LVIGHQISFLSRHLSIEAVSHTEALHG MSMEG_4450|M.smegmatis_MC2_155 QIVTDQIDFLNRHVGAGTR-------- Mb2330c|M.bovis_AF2122/97 VMLDAIRRFLTETAVLGQ--------- Rv2307c|M.tuberculosis_H37Rv VMLDAIRRFLTETAVLGQ--------- ** .