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MAQPLSYTRDDVTFMSDGTSCAAWLYRPDGVNNPPIVVLAHGFAAFRELRLDAYAARFAQAGYAALVFDY RHWGASDGQPRRILDIPKQQTDWRAAIAYARSLDNVDTTRLVGWGSSFGGGHVLTLAARDHEFAAAIVQV PHVSGPASAFSQSPKLVARLIAAGLRDQIGAWFGGAPHRVTSIGRPGEFAMMTSPGAYELVEEMAGGEAA EHMRAQLEAENDVAARIALRVPLYSPGRHAAKITAPTLVQLATKDDVTPYAKARKIVARIPNGEVRSYDI THFEPYVDPHFEQIVTDQIDFLNRHVGAGTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4450 | - | - | 100% (311) | alpha/beta hydrolase |
| M. smegmatis MC2 155 | MSMEG_2203 | - | 3e-40 | 34.65% (303) | alpha/beta hydrolase |
| M. smegmatis MC2 155 | MSMEG_0220 | - | 3e-10 | 27.12% (306) | monoglyceride lipase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2330c | - | 2e-07 | 27.94% (136) | hypothetical protein Mb2330c |
| M. gilvum PYR-GCK | Mflv_3976 | - | 4e-60 | 41.31% (305) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2307c | - | 2e-07 | 27.94% (136) | hypothetical protein Rv2307c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2608 | - | 4e-44 | 37.50% (304) | putative hydrolase, alpha/beta fold |
| M. marinum M | MMAR_0385 | - | 2e-66 | 44.52% (301) | hypothetical protein MMAR_0385 |
| M. avium 104 | MAV_2688 | - | 1e-10 | 42.19% (64) | alpha/beta hydrolase |
| M. thermoresistible (build 8) | TH_1408 | - | 1e-127 | 71.52% (302) | alpha/beta hydrolase |
| M. ulcerans Agy99 | MUL_1035 | - | 5e-65 | 43.93% (305) | hypothetical protein MUL_1035 |
| M. vanbaalenii PYR-1 | Mvan_2419 | - | 3e-58 | 40.79% (304) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4450|M.smegmatis_MC2_155 MAQPLSYTRDDVTFMSDGTSCAAWLYRP---DGVNNPPIVVLAHGFAAFR
TH_1408|M.thermoresistible__bu MAEHT-YVRHDTTFISEGDRCAAWLYRP---DGVQNPPLVVMAHGFAAFR
Mflv_3976|M.gilvum_PYR-GCK -----MPTRDDVRIPAHGDEIAAYVYRPP--AGVGATACVVMAHGFTGTR
Mvan_2419|M.vanbaalenii_PYR-1 ------MTRQEVQIPADGGQIAAYVYRPQ--VTGGGTACIVMAHGFTGTR
MMAR_0385|M.marinum_M -----MTQRQDVRFPCGEAMISAWLYRPAGADPARPVPMLVMAHGLGAVR
MUL_1035|M.ulcerans_Agy99 -----MTQRQDVRFPCGEALISAWLYRPAGADPARPVPMLVMAHGLGAVR
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 ------MNRQSIRFNSHGIDCEAWLYRAQ--TVEDTAPIVVMAHGVGGTK
Mb2330c|M.bovis_AF2122/97 -----MSLKRCRALPVVAIVALVASGVITFIWSQQRRLIYFPSAGPVPSA
Rv2307c|M.tuberculosis_H37Rv -----MSLKRCRALPVVAIVALVASGVIMFIWSQQRRLIYFPSAGPVPSA
MSMEG_4450|M.smegmatis_MC2_155 ELRLDAYAARFAQAGYAALVFDYRHWGASDGQPRRILDIPKQQTDWRAAI
TH_1408|M.thermoresistible__bu ELRLDAYADRFARAGYAVLVFDYRFWGASDGEPRRILDIKAQQADWRAAV
Mflv_3976|M.gilvum_PYR-GCK DDGLPDYAEAFRDAGYVVVLFDYRHFGASSGQPRQLLDMARQREDFHTVI
Mvan_2419|M.vanbaalenii_PYR-1 DDGLPDYAEAFCAAGHTVVLFDYRHFGASTGEPRQLLDIAEQRRDYHTVI
MMAR_0385|M.marinum_M TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MUL_1035|M.ulcerans_Agy99 TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 DSGLEPFAVRLAEAGMHALAFDYRGFGASDGFPRQHVSFTHQIGDYHAAV
Mb2330c|M.bovis_AF2122/97 SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
Rv2307c|M.tuberculosis_H37Rv SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
MSMEG_4450|M.smegmatis_MC2_155 AYARSLDNVDTTRLVGWGSSFGGGHVLTLAARDHEFAAAIVQVPHVSGPA
TH_1408|M.thermoresistible__bu SYARSLDSVDTTRLVAWGSSFGGGHVLHLLAHDHELAAGIAQVPHVDGPA
Mflv_3976|M.gilvum_PYR-GCK EWARRLDGVDPNRIVAWGSSFSGGHVLAVAAEDPRLAAVIAQAPFTDALA
Mvan_2419|M.vanbaalenii_PYR-1 AWARHLDGVDPNRIVVWGSSFSGGHVLAVAAEDPRIAAVIAQAPFTDALA
MMAR_0385|M.marinum_M AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MUL_1035|M.ulcerans_Agy99 AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 NMARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIA
Mb2330c|M.bovis_AF2122/97 ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS
Rv2307c|M.tuberculosis_H37Rv ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS
MSMEG_4450|M.smegmatis_MC2_155 SAFSQSPKLVARLIAAGLRDQIGAWFGGAPHRVTSIGRPGEFAMMTSPGA
TH_1408|M.thermoresistible__bu SAFAQPIGLVSRLFLAGVRDQVGAWFGAEPHRTAAVGRPGELAMMTSPGA
Mflv_3976|M.gilvum_PYR-GCK TLRNAPLRNIPPMVVAALRDQLGAWRNRPPRMLAAVGPPGDLAALTSPDA
Mvan_2419|M.vanbaalenii_PYR-1 TLREIPPGNIPLLLIAAVRDQVGAWRGRPPHTVAAVGSPGTVAALTSPDA
MMAR_0385|M.marinum_M SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA
MUL_1035|M.ulcerans_Agy99 SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA
MAV_2688|M.avium_104 --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997 AARSAMTEHSAGTLLRSAVTGLRSRLGRQQRTIPIVGRAGELAALTSDGY
Mb2330c|M.bovis_AF2122/97 DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG----
Rv2307c|M.tuberculosis_H37Rv DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG----
MSMEG_4450|M.smegmatis_MC2_155 YELVEEMAGGEAAEHMRAQLEAENDVAARIALRVPLYSPGRHAAKITAPT
TH_1408|M.thermoresistible__bu MDLVEQMAA-----DHREKLFTENNVAARIALRVPFYSPGRYASRITAPT
Mflv_3976|M.gilvum_PYR-GCK EPGFGAILG--------PESLWRNEFAARLMLRFAFERPGRKAATLQMPV
Mvan_2419|M.vanbaalenii_PYR-1 KPGFEAIIG--------PNSLWRNEFAARLMFTFAFNRPGRKAAKLRMPV
MMAR_0385|M.marinum_M YPGYLGLMP--------QGTQVPNEVAARIGIKVLGYRPGRSARKIACPI
MUL_1035|M.ulcerans_Agy99 YPGYLGLMP--------QGTQVPNEVAARIGIKVLGYRPGRSARKIACPI
MAV_2688|M.avium_104 ---------------------------------------------MSCPI
MAB_2608|M.abscessus_ATCC_1997 YEAHLAIAG----------PAWRNEIDATVGTQLVSYRPTRCASRIGCPI
Mb2330c|M.bovis_AF2122/97 --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV
Rv2307c|M.tuberculosis_H37Rv --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV
: *
MSMEG_4450|M.smegmatis_MC2_155 LVQLATKDDVTPYAKARKIVARIPNG----EVRSYDITHFEPYVDPHF-E
TH_1408|M.thermoresistible__bu LIQVARYDDVTPMDKALRVARRIPRG----EALVYDCRHFEPYLEPHF-E
Mflv_3976|M.gilvum_PYR-GCK LFCVCDDDVVTPPGPTIEAARRAPCG----ELRRYPYGHFDIYHDP----
Mvan_2419|M.vanbaalenii_PYR-1 LLCVCDDDVVTPPGPSVEAAHRAPRG----ELCRYPYGHFDIYHDP----
MMAR_0385|M.marinum_M LFCVCETDSVAPAGPTLRYAARAPRG----EVIRYPEGHFAIYLGDAF-E
MUL_1035|M.ulcerans_Agy99 LFCVCETDSVAPAGPTLRYAARAPRGEVSGEVIRYPEGHFAIYLGDAF-E
MAV_2688|M.avium_104 LFAICENDTVAPAKATQKYAAQAPRG----EIKLYDAGHFDIYVGADF-E
MAB_2608|M.abscessus_ATCC_1997 LVQIADFDRAAPPHAAAKAAFKARAE-----VRHYPCDHFGVYHGQECHE
Mb2330c|M.bovis_AF2122/97 LVIAGGSDDIVPATLSEWLVAAAAEPK--RYVVVPGVGHNDPELLDGR--
Rv2307c|M.tuberculosis_H37Rv LVIAGGSDDIVPATLSERLVAAAAEPK--RYVVVPGVGHNDPELLDGR--
*. * .* : . *
MSMEG_4450|M.smegmatis_MC2_155 QIVTDQIDFLNRHVGAGTR--------
TH_1408|M.thermoresistible__bu KIVSDQIDFLHRHVGQR----------
Mflv_3976|M.gilvum_PYR-GCK QVKADQLEFLHRALARGGR--------
Mvan_2419|M.vanbaalenii_PYR-1 KVKADQLEFLARVVGDRTA--------
MMAR_0385|M.marinum_M RVVADQLGFLDKHLKPAGQP-------
MUL_1035|M.ulcerans_Agy99 HVVADQLGFLDKHLKPAGQP-------
MAV_2688|M.avium_104 RNVTDQLNFLSRHVPVS----------
MAB_2608|M.abscessus_ATCC_1997 LVIGHQISFLSRHLSIEAVSHTEALHG
Mb2330c|M.bovis_AF2122/97 VMLDAIRRFLTETAVLGQ---------
Rv2307c|M.tuberculosis_H37Rv VMLDAIRRFLTETAVLGQ---------
** .