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MNRQSIRFNSHGIDCEAWLYRAQTVEDTAPIVVMAHGVGGTKDSGLEPFAVRLAEAGMHALAFDYRGFGA SDGFPRQHVSFTHQIGDYHAAVNMARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDG IAAARSAMTEHSAGTLLRSAVTGLRSRLGRQQRTIPIVGRAGELAALTSDGYYEAHLAIAGPAWRNEIDA TVGTQLVSYRPTRCASRIGCPILVQIADFDRAAPPHAAAKAAFKARAEVRHYPCDHFGVYHGQECHELVI GHQISFLSRHLSIEAVSHTEALHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2608 | - | - | 100% (304) | putative hydrolase, alpha/beta fold |
| M. abscessus ATCC 19977 | MAB_3704 | - | 5e-09 | 31.06% (132) | hypothetical protein MAB_3704 |
| M. abscessus ATCC 19977 | MAB_0923c | - | 4e-06 | 31.30% (131) | hypothetical protein MAB_0923c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0189 | - | 4e-07 | 28.08% (260) | lysophospholipase |
| M. gilvum PYR-GCK | Mflv_4372 | - | 1e-84 | 52.36% (296) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0183 | - | 4e-07 | 28.08% (260) | lysophospholipase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0385 | - | 1e-51 | 39.46% (294) | hypothetical protein MMAR_0385 |
| M. avium 104 | MAV_2688 | - | 1e-06 | 38.81% (67) | alpha/beta hydrolase |
| M. smegmatis MC2 155 | MSMEG_2203 | - | 1e-81 | 49.49% (297) | alpha/beta hydrolase |
| M. thermoresistible (build 8) | TH_2707 | - | 1e-70 | 51.69% (267) | PUTATIVE putative alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_1035 | - | 2e-50 | 38.59% (298) | hypothetical protein MUL_1035 |
| M. vanbaalenii PYR-1 | Mvan_1972 | - | 4e-78 | 49.16% (297) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4372|M.gilvum_PYR-GCK --MSRTEVAFPSGGDTCSAWHFAAD------GVRRPVVVMAHGFGGTKDS
Mvan_1972|M.vanbaalenii_PYR-1 --MTRSEISFRSGQDACSGWHFTSG------GALRRVVVMAHGFGGTKDS
MSMEG_2203|M.smegmatis_MC2_155 --MTYTEFTFHSGGQRCSAWHFPAGS----GGSGNPVVVMAHGFGGTKDS
MAB_2608|M.abscessus_ATCC_1997 --MNRQSIRFNSHGIDCEAWLYRAQT----VEDTAPIVVMAHGVGGTKDS
TH_2707|M.thermoresistible__bu --MSNPLRIPAEGGAMLAASHFPATSDALRGPNGRPGVVMAHGLGATRDS
MMAR_0385|M.marinum_M -MTQRQDVRFPCGEAMISAWLYRPAG--ADPARPVPMLVMAHGLGAVRTM
MUL_1035|M.ulcerans_Agy99 -MTQRQDVRFPCGEALISAWLYRPAG--ADPARPVPMLVMAHGLGAVRTM
MAV_2688|M.avium_104 --------------------------------------------------
Mb0189|M.bovis_AF2122/97 MTTTRTERNFAGIGDVRIVYDVWTPD-----TAPQAVVVLAHGLG-EHAR
Rv0183|M.tuberculosis_H37Rv MTTTRTERNFAGIGDVRIVYDVWTPD-----TAPQAVVVLAHGLG-EHAR
Mflv_4372|M.gilvum_PYR-GCK GLEPFALRFAEAGFDVFAFDYRGFGASEGTPRQSLSVRRQIDDYHAAIHA
Mvan_1972|M.vanbaalenii_PYR-1 GLEPFAQRFAAAGIDVLAFDYRGFGASGGVPRQSLSVRRQIDDYNAAVEA
MSMEG_2203|M.smegmatis_MC2_155 GLQPFAERFSAAGLDAVAFDYRGFGASEGEPRQSISVERQLADYDAAIRA
MAB_2608|M.abscessus_ATCC_1997 GLEPFAVRLAEAGMHALAFDYRGFGASDGFPRQHVSFTHQIGDYHAAVNM
TH_2707|M.thermoresistible__bu GLAGFAAALADAGADVITFDYRNFAESDGTPRQLVSLRGQIRDYHAALRY
MMAR_0385|M.marinum_M RLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAVAY
MUL_1035|M.ulcerans_Agy99 RLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAVAY
MAV_2688|M.avium_104 --------------------------------------------------
Mb0189|M.bovis_AF2122/97 RYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVGI
Rv0183|M.tuberculosis_H37Rv RYDHVAQRLGAAGLVTYALDHRGHGRSGGKRVLVRDISEYTADFDTLVGI
Mflv_4372|M.gilvum_PYR-GCK ARQLDGVDPDRVALWGASFSGGHVVRVAAERADVAAVIALTPLTSGVAVS
Mvan_1972|M.vanbaalenii_PYR-1 AKTLDGVDPSRVGLWGASFSGGHVLRVAAERDDIGAVISLTPLTSGLAVS
MSMEG_2203|M.smegmatis_MC2_155 AQAMPGVDPRKVVLWGSSFSGSHVLRAAARNTDVAAVIAMTPLTSGLAAS
MAB_2608|M.abscessus_ATCC_1997 ARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIAAA
TH_2707|M.thermoresistible__bu LRSMPDVDARRVAVWGVSLSGGHVLKVAAEDPAVAAVISVTPAVDGLAAV
MMAR_0385|M.marinum_M ARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIASV
MUL_1035|M.ulcerans_Agy99 ARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIASV
MAV_2688|M.avium_104 --------------------------------------------------
Mb0189|M.bovis_AF2122/97 ATR--EYPGCKRIVLGHSMGGGIVFAYGVERPDNYDLMVLS---------
Rv0183|M.tuberculosis_H37Rv ATR--EYPGCKRIVLGHSMGGGIVFAYGVERPDNYDLMVLS---------
Mflv_4372|M.gilvum_PYR-GCK RSAMASRDTVTSLKWTLTGLKSRIAVGRGGSPTLMPLVSPVGQPGALALE
Mvan_1972|M.vanbaalenii_PYR-1 RAAAASRDMVTSLRWTLTGVRSRFAVRRGGRPTMMPLVAPVGEPGALALD
MSMEG_2203|M.smegmatis_MC2_155 RAAVTQRDVATALRWTLKGVKSRVAAAVGGAPTMMPLTAKPGEPGALALD
MAB_2608|M.abscessus_ATCC_1997 RSAMTEHSAGTLLRSAVTGLRSRLGRQQ----RTIPIVGRAGELAALTSD
TH_2707|M.thermoresistible__bu ATLARANGPVHLAKLVGRGLSDVLAAALGRPPVPAPIVGHPGELAALTAP
MMAR_0385|M.marinum_M LAIAPT----TAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAP
MUL_1035|M.ulcerans_Agy99 LAIAPT----TAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAP
MAV_2688|M.avium_104 --------------------------------------------------
Mb0189|M.bovis_AF2122/97 APAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
Rv0183|M.tuberculosis_H37Rv APAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNT
Mflv_4372|M.gilvum_PYR-GCK GAYESYTALA--GPTWRNEIDSSIGLQVVGVRTTAAAKKLRCPLLVQIAD
Mvan_1972|M.vanbaalenii_PYR-1 GAYESYTALA--GPTWRNEIDSSVGLEVVGVRTNAAAKKMRCPLLVQIAD
MSMEG_2203|M.smegmatis_MC2_155 GAYESYLSIA--GPTWRNEVDAGVGMELARVRTAAAAKALKCPVLVQIAD
MAB_2608|M.abscessus_ATCC_1997 GYYEAHLAIA--GPAWRNEIDATVGTQLVSYRPTRCASRIGCPILVQIAD
TH_2707|M.thermoresistible__bu GAVEGMLTTA--GPSWRNAIAARLFLQMGTYRPIADVSRVQCPVLMQIAD
MMAR_0385|M.marinum_M DAYPGYLGLMPQGTQVPNEVAARIGIKVLGYRPGRSARKIACPILFCVCE
MUL_1035|M.ulcerans_Agy99 DAYPGYLGLMPQGTQVPNEVAARIGIKVLGYRPGRSARKIACPILFCVCE
MAV_2688|M.avium_104 ---------------------------------------MSCPILFAICE
Mb0189|M.bovis_AF2122/97 DPLVHHGRVP---------AGIGRALLQVGETMPRRAPALTAPLLVLHGT
Rv0183|M.tuberculosis_H37Rv DPLVHHGRVP---------AGIGRALLQVGETMPRRAPALTAPLLVLHGT
: .*:*.
Mflv_4372|M.gilvum_PYR-GCK FDQYVPADAVAKTAAHGRAQ-----VHHYACDHFDVWPGNDWFDKTVTDQ
Mvan_1972|M.vanbaalenii_PYR-1 FDQYVPAAAVATTAAHGRAQ-----VHHYPCDHFDVWPGHDWFDKTVSDQ
MSMEG_2203|M.smegmatis_MC2_155 FDRFVPADSVAKTAVQARAQ-----VHHYACDHFDVWPGHDWFDTAVTDQ
MAB_2608|M.abscessus_ATCC_1997 FDRAAPPHAAAKAAFKARAE-----VRHYPCDHFGVYHGQECHELVIGHQ
TH_2707|M.thermoresistible__bu HDQSAPPAAATRAATRLGAT-----VHRYPCDHFDVYPGTSCHDRAVAHQ
MMAR_0385|M.marinum_M TDSVAPAGPTLRYAARAPRG----EVIRYPEGHFAIYLG-DAFERVVADQ
MUL_1035|M.ulcerans_Agy99 TDSVAPAGPTLRYAARAPRGEVSGEVIRYPEGHFAIYLG-DAFEHVVADQ
MAV_2688|M.avium_104 NDTVAPAKATQKYAAQAPRG----EIKLYDAGHFDIYVG-ADFERNVTDQ
Mb0189|M.bovis_AF2122/97 DDRLIPIEGSRRLVECVGSAD--VQLKEYPGLYHEVFNE-PERNQVLDDV
Rv0183|M.tuberculosis_H37Rv DDRLIPIEGSRRLVECVGSAD--VQLKEYPGLYHEVFNE-PERNQVLDDV
* * . : * :. :: : : .
Mflv_4372|M.gilvum_PYR-GCK IAFLRRTLTRQ----------
Mvan_1972|M.vanbaalenii_PYR-1 VAFLTRTFSVVRGTLID----
MSMEG_2203|M.smegmatis_MC2_155 IAFLRRTLSLR----------
MAB_2608|M.abscessus_ATCC_1997 ISFLSRHLSIEAVSHTEALHG
TH_2707|M.thermoresistible__bu VAFLRRVLAPAEVAS------
MMAR_0385|M.marinum_M LGFLDKHLKPAGQP-------
MUL_1035|M.ulcerans_Agy99 LGFLDKHLKPAGQP-------
MAV_2688|M.avium_104 LNFLSRHVPVS----------
Mb0189|M.bovis_AF2122/97 VAWLTERL-------------
Rv0183|M.tuberculosis_H37Rv VAWLTERL-------------
: :* . .