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M. thermoresistible (build 8) TH_2570 (-)

annotation: alpha/beta hydrolase fold
coordinates: 3796530 - 3797420
length: 297

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2570--100% (297)alpha/beta hydrolase fold
M. thermoresistible (build 8)TH_1408-9e-6545.42% (295) alpha/beta hydrolase
M. thermoresistible (build 8)TH_2707-5e-5744.82% (299) PUTATIVE putative alpha/beta hydrolase fold

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2330c-7e-1030.71% (127) hypothetical protein Mb2330c
M. gilvum PYR-GCKMflv_3976-1e-12170.21% (292) dienelactone hydrolase
M. tuberculosis H37RvRv2307c-7e-1030.71% (127) hypothetical protein Rv2307c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2608-2e-5240.74% (297) putative hydrolase, alpha/beta fold
M. marinum MMMAR_0385-6e-7349.14% (291) hypothetical protein MMAR_0385
M. avium 104MAV_2688-7e-0838.33% (60) alpha/beta hydrolase
M. smegmatis MC2 155MSMEG_4450-4e-6343.46% (306) alpha/beta hydrolase
M. ulcerans Agy99MUL_1035-3e-7148.47% (295) hypothetical protein MUL_1035
M. vanbaalenii PYR-1Mvan_2419-1e-12269.90% (289) alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3976|M.gilvum_PYR-GCK          -----MPTRDDVRIPAHGDEIAAYVYRPPAGVGA--TACVVMAHGFTGTR
Mvan_2419|M.vanbaalenii_PYR-1       ------MTRQEVQIPADGGQIAAYVYRPQVTGGG--TACIVMAHGFTGTR
TH_2570|M.thermoresistible__bu      ---MATTDRRDLRIPAHGEQLAAYFYPPAGAGPT--TPCIVMAHGFTATR
MMAR_0385|M.marinum_M               -----MTQRQDVRFPCGEAMISAWLYRPAGADPARPVPMLVMAHGLGAVR
MUL_1035|M.ulcerans_Agy99           -----MTQRQDVRFPCGEALISAWLYRPAGADPARPVPMLVMAHGLGAVR
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      ------MNRQSIRFNSHGIDCEAWLYRAQTVEDT--APIVVMAHGVGGTK
MSMEG_4450|M.smegmatis_MC2_155      MAQPLSYTRDDVTFMSDGTSCAAWLYRPDGVNNP---PIVVLAHGFAAFR
Mb2330c|M.bovis_AF2122/97           ---MSLKRCRALPVVAIVALVASGVITFIWSQQR--RLIYFPSAGPVPSA
Rv2307c|M.tuberculosis_H37Rv        ---MSLKRCRALPVVAIVALVASGVIMFIWSQQR--RLIYFPSAGPVPSA
                                                                                      

Mflv_3976|M.gilvum_PYR-GCK          DDGLPDYAEAFRDAGYVVVLFDYRHFGASSGQPRQLLDMARQREDFHTVI
Mvan_2419|M.vanbaalenii_PYR-1       DDGLPDYAEAFCAAGHTVVLFDYRHFGASTGEPRQLLDIAEQRRDYHTVI
TH_2570|M.thermoresistible__bu      DDGLPAYAEAFHAAGYAVVLFDYRHFGASTGEPRQLLDITRQHDDYRAVV
MMAR_0385|M.marinum_M               TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MUL_1035|M.ulcerans_Agy99           TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      DSGLEPFAVRLAEAGMHALAFDYRGFGASDGFPRQHVSFTHQIGDYHAAV
MSMEG_4450|M.smegmatis_MC2_155      ELRLDAYAARFAQAGYAALVFDYRHWGASDGQPRRILDIPKQQTDWRAAI
Mb2330c|M.bovis_AF2122/97           SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
Rv2307c|M.tuberculosis_H37Rv        SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
                                                                                      

Mflv_3976|M.gilvum_PYR-GCK          EWARRLDGVDPNRIVAWGSSFSGGHVLAVAAEDPRLAAVIAQAPFTDALA
Mvan_2419|M.vanbaalenii_PYR-1       AWARHLDGVDPNRIVVWGSSFSGGHVLAVAAEDPRIAAVIAQAPFTDALA
TH_2570|M.thermoresistible__bu      AWARTQPGVDPDRIVLWGSSFSGGHVLVVAADDPRIAAVISQAPFTDAVP
MMAR_0385|M.marinum_M               AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MUL_1035|M.ulcerans_Agy99           AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      NMARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIA
MSMEG_4450|M.smegmatis_MC2_155      AYARSLDNVDTTRLVGWGSSFGGGHVLTLAARDHEFAAAIVQVPHVSGPA
Mb2330c|M.bovis_AF2122/97           ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS
Rv2307c|M.tuberculosis_H37Rv        ELAVALHGLGLSVLLFDYRGYGG--NPGRPSEQGLAADARAAQEWLSGQS
                                                                                      

Mflv_3976|M.gilvum_PYR-GCK          TLRNAPLRNIPPMVVAALRDQLGAWRNRPPRMLAAVGPPGDLAALTSPDA
Mvan_2419|M.vanbaalenii_PYR-1       TLREIPPGNIPLLLIAAVRDQVGAWRGRPPHTVAAVGSPGTVAALTSPDA
TH_2570|M.thermoresistible__bu      TLRKVPPATIARLAVAGLRDQIGSWRGRPPRTASAVGAPGAVAAMTTPDA
MMAR_0385|M.marinum_M               SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA
MUL_1035|M.ulcerans_Agy99           SVLAIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGKPGEVALMTAPDA
MAV_2688|M.avium_104                --------------------------------------------------
MAB_2608|M.abscessus_ATCC_1997      AARSAMTEHSAGTLLRSAVTGLRSRLGRQQRTIPIVGRAGELAALTSDGY
MSMEG_4450|M.smegmatis_MC2_155      SAFSQSPKLVARLIAAGLRDQIGAWFGGAPHRVTSIGRPGEFAMMTSPGA
Mb2330c|M.bovis_AF2122/97           DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG----
Rv2307c|M.tuberculosis_H37Rv        DVDPARIAYFGESLGAAVAVGLAVQ--RPPAALVLRSPFTSLAEVG----
                                                                                      

Mflv_3976|M.gilvum_PYR-GCK          EPGFGAILGPES--------LWRNEFAARLMLRFAFERPGRKAATLQMPV
Mvan_2419|M.vanbaalenii_PYR-1       KPGFEAIIGPNS--------LWRNEFAARLMFTFAFNRPGRKAAKLRMPV
TH_2570|M.thermoresistible__bu      EPGFRAIVEPDS--------LWRNEFAARLMLRFPFYRPVRVAGRINAPL
MMAR_0385|M.marinum_M               YPGYLGLMPQGT--------QVPNEVAARIGIKVLGYRPGRSARKIACPI
MUL_1035|M.ulcerans_Agy99           YPGYLGLMPQGT--------QVPNEVAARIGIKVLGYRPGRSARKIACPI
MAV_2688|M.avium_104                ---------------------------------------------MSCPI
MAB_2608|M.abscessus_ATCC_1997      YEAHLAIAGP----------AWRNEIDATVGTQLVSYRPTRCASRIGCPI
MSMEG_4450|M.smegmatis_MC2_155      YELVEEMAGGEAAEHMRAQLEAENDVAARIALRVPLYSPGRHAAKITAPT
Mb2330c|M.bovis_AF2122/97           --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV
Rv2307c|M.tuberculosis_H37Rv        --------------------AVHYPWLPLRRLLLDHYPSIERIASVHAPV
                                                                                 :  * 

Mflv_3976|M.gilvum_PYR-GCK          LFCVCDDDVVTPPGPTIEAARRAPCG----ELRRYPYGHFDIYHD----P
Mvan_2419|M.vanbaalenii_PYR-1       LLCVCDDDVVTPPGPSVEAAHRAPRG----ELCRYPYGHFDIYHD----P
TH_2570|M.thermoresistible__bu      LVCVCDDDAVTPPEPAIEAARRAPRG----QLRRYPYGHFDIYHD----P
MMAR_0385|M.marinum_M               LFCVCETDSVAPAGPTLRYAARAPRG----EVIRYPEGHFAIYLG-DAFE
MUL_1035|M.ulcerans_Agy99           LFCVCETDSVAPAGPTLRYAARAPRGEVSGEVIRYPEGHFAIYLG-DAFE
MAV_2688|M.avium_104                LFAICENDTVAPAKATQKYAAQAPRG----EIKLYDAGHFDIYVG-ADFE
MAB_2608|M.abscessus_ATCC_1997      LVQIADFDRAAPPHAAAK-AAFKARA----EVRHYPCDHFGVYHGQECHE
MSMEG_4450|M.smegmatis_MC2_155      LVQLATKDDVTPYAKARKIVARIPNG----EVRSYDITHFEPYVD-PHFE
Mb2330c|M.bovis_AF2122/97           LVIAGGSDDIVPATLSEWLVAAAAEPKRYVVVPGVGHNDPELLDG----R
Rv2307c|M.tuberculosis_H37Rv        LVIAGGSDDIVPATLSERLVAAAAEPKRYVVVPGVGHNDPELLDG----R
                                    *.     *  .*   :   .   .       :      .     .     

Mflv_3976|M.gilvum_PYR-GCK          QVKADQLEFLHRALARGGR--------
Mvan_2419|M.vanbaalenii_PYR-1       KVKADQLEFLARVVGDRTA--------
TH_2570|M.thermoresistible__bu      QVKSDQLDFLRQVLGTG----------
MMAR_0385|M.marinum_M               RVVADQLGFLDKHLKPAGQP-------
MUL_1035|M.ulcerans_Agy99           HVVADQLGFLDKHLKPAGQP-------
MAV_2688|M.avium_104                RNVTDQLNFLSRHVPVS----------
MAB_2608|M.abscessus_ATCC_1997      LVIGHQISFLSRHLSIEAVSHTEALHG
MSMEG_4450|M.smegmatis_MC2_155      QIVTDQIDFLNRHVGAGTR--------
Mb2330c|M.bovis_AF2122/97           VMLDAIRRFLTETAVLGQ---------
Rv2307c|M.tuberculosis_H37Rv        VMLDAIRRFLTETAVLGQ---------
                                            ** .